iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068623

Ensembl Protein ID

EAA32114

UniProt Accession

Q1K7R0; Q1K7R0_NEUCR

Genbank Protein ID

EAA32114.1

Protein Name

Ubiquitin-conjugating enzyme E

Genbank Nucleotide ID

CM002240

Gene Name

NCU03623

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU03623	EAA32114	EAA32114

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.00e-50	170.2	9	157

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........eee 90
           Rl +e+ +l+++ppegi+a+p +e+dl +we+li Gpe+tp+eggvF +e++fp+dYP  PP++kfl  ifhPnvy++G vC+sil+            +e
   Q: 9    RLLQEYRALTNNPPEGITAGPISEDDLLHWECLIQGPEGTPFEGGVFPAELKFPNDYPHMPPTMKFLGDIFHPNVYPSGLVCISILHppgddpnhyetASE 109
           899***********************************************************************************88889999999999* PP
   S: 91   kWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +Wsp +sve++lls++s+laepn esp+n+eaa++++++r+ey+ +v+
   Q: 110  RWSPIQSVEKILLSVMSMLAEPNDESPANVEAAKMWREKRSEYEARVK 157
           *********************************************997 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MSLNVAQRRL LQEYRALTNN PPEGITAGPI SEDDLLHWEC LIQGPEGTPF EGGVFPAELK 60
FPNDYPHMPP TMKFLGDIFH PNVYPSGLVC ISILHPPGDD PNHYETASER WSPIQSVEKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATCAATC CCCGCCGAGC GGACCGACGT CAGACGTGTC AAGCAACTGC GCCGCTGACA 60
ACCCCCGCTG CAGCCCAGTG TGTCCTCCGC GCTTCTCCTG CATGCATCGA TTCAGTTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0000837--C:Doa10p ubiquitin ligase complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006333--P:chromatin assembly or disassembly
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0031505--P:fungal-type cell wall organization
GO:0010620--P:negative regulation of transcription by transcription factor catabolism
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ncr:NCU03623

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000411	Aegilops tauschii	40.91	1.00e-35	140.00
IUUC-Aml-002172	Ailuropoda melanoleuca	62.42	3.00e-55	205.00
IUUC-Atr-003150	Amborella trichopoda	55.10	4.00e-38	148.00
IUUC-Apl-003761	Anas platyrhynchos	65.19	6.00e-58	214.00
IUUC-Aca-005062	Anolis carolinensis	63.58	9.00e-58	213.00
IUUC-Aly-005673	Arabidopsis lyrata	58.33	9.00e-44	167.00
IUUC-Ath-007644	Arabidopsis thaliana	58.33	9.00e-44	167.00
IUUC-Ago-007853	Ashbya gossypii	62.35	7.00e-60	220.00
IUUC-Acl-008080	Aspergillus clavatus	79.27	1.00e-76	276.00
IUUC-Afl-008478	Aspergillus flavus	76.83	3.00e-75	271.00
IUUC-Afu-009051	Aspergillus fumigatus	79.27	9.00e-77	276.00
IUUC-Ani-009271	Aspergillus nidulans	76.83	2.00e-67	246.00
IUUC-Ang-009748	Aspergillus niger	78.66	3.00e-76	275.00
IUUC-Aor-010228	Aspergillus oryzae	77.44	2.00e-75	272.00
IUUC-Ate-010293	Aspergillus terreus	78.05	6.00e-76	274.00
IUUC-Ame-011698	Astyanax mexicanus	66.67	7.00e-63	230.00
IUUC-Bgr-012226	Blumeria graminis	79.52	2.00e-77	279.00
IUUC-Bta-013324	Bos taurus	57.14	2.00e-44	169.00
IUUC-Bci-013676	Botrytis cinerea	79.52	1.00e-77	280.00
IUUC-Bdi-014838	Brachypodium distachyon	53.25	1.00e-44	170.00
IUUC-Bol-016383	Brassica oleracea	57.34	2.00e-48	182.00
IUUC-Bra-017903	Brassica rapa	53.37	7.00e-44	167.00
IUUC-Cel-018676	Caenorhabditis elegans	63.98	1.00e-60	223.00
IUUC-Cja-019767	Callithrix jacchus	63.19	4.00e-59	218.00
IUUC-Cfa-020047	Canis familiaris	61.96	2.00e-58	216.00
IUUC-Cpo-021507	Cavia porcellus	63.19	3.00e-59	218.00
IUUC-Cre-022895	Chlamydomonas reinhardtii	53.37	3.00e-46	175.00
IUUC-Csa-023745	Chlorocebus sabaeus	61.96	3.00e-57	211.00
IUUC-Cho-024667	Choloepus hoffmanni	39.49	3.00e-27	112.00
IUUC-Cin-025310	Ciona intestinalis	65.22	2.00e-61	226.00
IUUC-Csv-025961	Ciona savignyi	62.73	2.00e-59	219.00
IUUC-Cgl-026553	Colletotrichum gloeosporioides	84.94	7.00e-83	297.00
IUUC-Cne-026903	Cryptococcus neoformans	61.59	3.00e-53	198.00
IUUC-Cme-027321	Cyanidioschyzon merolae	56.89	2.00e-44	169.00
IUUC-Dre-027900	Danio rerio	66.67	9.00e-63	230.00
IUUC-Dno-029688	Dasypus novemcinctus	64.05	1.00e-55	206.00
IUUC-Dor-030686	Dipodomys ordii	47.90	2.00e-41	160.00
IUUC-Dse-031253	Dothistroma septosporum	79.14	2.00e-77	278.00
IUUC-Dme-031849	Drosophila melanogaster	68.32	3.00e-63	231.00
IUUC-Ete-033010	Echinops telfairi	63.19	8.00e-58	214.00
IUUC-Eca-033294	Equus caballus	63.69	1.00e-56	209.00
IUUC-Eeu-034947	Erinaceus europaeus	51.97	2.00e-30	122.00
IUUC-Fca-036442	Felis catus	62.04	2.00e-48	182.00
IUUC-Fal-037188	Ficedula albicollis	64.71	3.00e-56	209.00
IUUC-Fox-037762	Fusarium oxysporum	87.12	5.00e-84	301.00
IUUC-Fso-038181	Fusarium solani	86.50	3.00e-83	298.00
IUUC-Gmo-038663	Gadus morhua	65.43	6.00e-62	227.00
IUUC-Ggr-039808	Gaeumannomyces graminis	84.94	3.00e-83	298.00
IUUC-Gga-040355	Gallus gallus	64.20	9.00e-60	220.00
IUUC-Gac-041847	Gasterosteus aculeatus	63.80	3.00e-61	225.00
IUUC-Gma-044131	Glycine max	55.78	1.00e-37	146.00
IUUC-Ggo-045202	Gorilla gorilla	63.19	2.00e-59	219.00
IUUC-Hsa-046369	Homo sapiens	63.19	2.00e-59	219.00
IUUC-Hvu-047065	Hordeum vulgare	54.36	2.00e-43	167.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	62.58	7.00e-59	217.00
IUUC-Kpa-049317	Komagataella pastoris	61.35	1.00e-58	216.00
IUUC-Lch-049596	Latimeria chalumnae	61.31	2.00e-57	213.00
IUUC-Lpe-051124	Leersia perrieri	54.17	2.00e-42	163.00
IUUC-Loc-052346	Lepisosteus oculatus	68.29	2.00e-47	178.00
IUUC-Lma-053126	Leptosphaeria maculans	76.52	1.00e-58	216.00
IUUC-Laf-054560	Loxodonta africana	61.64	1.00e-55	206.00
IUUC-Mcc-055172	Macaca mulatta	63.19	2.00e-59	219.00
IUUC-Meu-056891	Macropus eugenii	63.06	4.00e-56	208.00
IUUC-Mor-057260	Magnaporthe oryzae	84.34	1.00e-83	299.00
IUUC-Mpo-057468	Magnaporthe poae	84.34	9.00e-83	296.00
IUUC-Mtr-058406	Medicago truncatula	57.14	1.00e-44	169.00
IUUC-Mla-059084	Melampsora laricipopulina	58.48	2.00e-54	202.00
IUUC-Mga-059939	Meleagris gallopavo	63.29	6.00e-57	211.00
IUUC-Mvi-060514	Microbotryum violaceum	61.08	4.00e-57	211.00
IUUC-Mmr-061029	Microcebus murinus	59.04	7.00e-53	197.00
IUUC-Mdo-061820	Monodelphis domestica	63.19	1.00e-59	219.00
IUUC-Mmu-063123	Mus musculus	63.19	2.00e-59	219.00
IUUC-Mac-065294	Musa acuminata	55.03	6.00e-43	164.00
IUUC-Mpu-065866	Mustela putorius furo	60.49	3.00e-55	205.00
IUUC-Mlu-067220	Myotis lucifugus	63.69	2.00e-56	209.00
IUUC-Nfi-068395	Neosartorya fischeri	79.27	9.00e-77	276.00
IUUC-Nle-070007	Nomascus leucogenys	63.19	2.00e-59	219.00
IUUC-Opr-070958	Ochotona princeps	57.43	6.00e-45	171.00
IUUC-Ont-071736	Oreochromis niloticus	64.81	6.00e-62	227.00
IUUC-Oan-073475	Ornithorhynchus anatinus	63.06	5.00e-56	207.00
IUUC-Ocu-074820	Oryctolagus cuniculus	65.13	2.00e-56	209.00
IUUC-Oba-075915	Oryza barthii	54.86	7.00e-48	181.00
IUUC-Obr-076863	Oryza brachyantha	52.78	7.00e-41	157.00
IUUC-Ogl-076981	Oryza glaberrima	54.86	7.00e-48	181.00
IUUC-Ogu-078183	Oryza glumaepatula	54.86	7.00e-48	181.00
IUUC-Oin-079755	Oryza indica	54.86	7.00e-48	181.00
IUUC-Olo-080576	Oryza longistaminata	54.86	7.00e-48	181.00
IUUC-Ome-081190	Oryza meridionalis	51.63	2.00e-45	172.00
IUUC-Oni-083010	Oryza nivara	54.86	7.00e-48	181.00
IUUC-Opu-083784	Oryza punctata	54.17	2.00e-42	162.00
IUUC-Oru-084817	Oryza rufipogon	54.86	7.00e-48	181.00
IUUC-Osa-085291	Oryza sativa	54.86	7.00e-48	181.00
IUUC-Ola-087571	Oryzias latipes	65.43	1.00e-61	226.00
IUUC-Olu-087887	Ostreococcus lucimarinus	53.25	1.00e-48	183.00
IUUC-Oga-088473	Otolemur garnettii	55.48	4.00e-45	172.00
IUUC-Oar-089706	Ovis aries	63.19	2.00e-59	219.00
IUUC-Ptr-090798	Pan troglodytes	63.19	2.00e-59	219.00
IUUC-Pan-091967	Papio anubis	63.19	2.00e-59	219.00
IUUC-Psi-093524	Pelodiscus sinensis	66.00	4.00e-56	208.00
IUUC-Pma-094602	Petromyzon marinus	66.19	6.00e-53	197.00
IUUC-Pno-094979	Phaeosphaeria nodorum	76.40	7.00e-74	267.00
IUUC-Ppa-095611	Physcomitrella patens	52.76	3.00e-50	189.00
IUUC-Pfo-097330	Poecilia formosa	65.03	1.00e-61	226.00
IUUC-Pab-098225	Pongo abelii	62.58	9.00e-59	217.00
IUUC-Pop-099940	Populus trichocarpa	57.05	2.00e-44	169.00
IUUC-Pca-101040	Procavia capensis	64.05	1.00e-55	206.00
IUUC-Ppe-101778	Prunus persica	57.82	2.00e-45	172.00
IUUC-Pva-103074	Pteropus vampyrus	57.14	4.00e-44	169.00
IUUC-Pgr-103674	Puccinia graminis	58.24	2.00e-53	199.00
IUUC-Ptt-103840	Puccinia triticina	57.06	1.00e-52	197.00
IUUC-Pte-104389	Pyrenophora teres	76.40	7.00e-74	267.00
IUUC-Pyt-104703	Pyrenophora triticirepentis	77.64	2.00e-74	269.00
IUUC-Rno-105228	Rattus norvegicus	63.19	2.00e-59	219.00
IUUC-Sce-106233	Saccharomyces cerevisiae	60.49	2.00e-56	209.00
IUUC-Sha-107274	Sarcophilus harrisii	64.05	7.00e-56	207.00
IUUC-Sja-107937	Schizosaccharomyces japonicus	67.47	6.00e-67	244.00
IUUC-Spo-108269	Schizosaccharomyces pombe	68.67	3.00e-67	245.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	81.93	7.00e-80	287.00
IUUC-Smo-109401	Selaginella moellendorffii	52.44	1.00e-36	143.00
IUUC-Sit-110784	Setaria italica	54.86	1.00e-42	164.00
IUUC-Sly-111177	Solanum lycopersicum	57.82	6.00e-45	171.00
IUUC-Stu-112865	Solanum tuberosum	58.67	3.00e-45	172.00
IUUC-Sbi-113787	Sorghum bicolor	50.30	3.00e-44	168.00
IUUC-Sre-114952	Sporisorium reilianum	62.05	3.00e-56	208.00
IUUC-Ssc-115365	Sus scrofa	63.23	5.00e-56	207.00
IUUC-Tgu-116816	Taeniopygia guttata	64.20	9.00e-60	220.00
IUUC-Tru-118443	Takifugu rubripes	53.25	2.00e-45	172.00
IUUC-Tsy-119168	Tarsius syrichta	57.14	7.00e-44	168.00
IUUC-Tni-120278	Tetraodon nigroviridis	62.80	2.00e-58	216.00
IUUC-Tca-121649	Theobroma cacao	54.42	7.00e-41	157.00
IUUC-Tre-122131	Trichoderma reesei	86.14	5.00e-84	301.00
IUUC-Tvi-122669	Trichoderma virens	86.14	5.00e-84	301.00
IUUC-Tae-123772	Triticum aestivum	54.55	7.00e-46	174.00
IUUC-Tur-126873	Triticum urartu	54.73	2.00e-44	170.00
IUUC-Tme-127052	Tuber melanosporum	70.48	5.00e-69	251.00
IUUC-Tbe-127792	Tupaia belangeri	63.19	2.00e-59	219.00
IUUC-Ttr-128609	Tursiops truncatus	57.14	5.00e-44	169.00
IUUC-Uma-129587	Ustilago maydis	62.05	2.00e-56	209.00
IUUC-Vda-129914	Verticillium dahliae	82.53	6.00e-82	294.00
IUUC-Vpa-130208	Vicugna pacos	57.43	6.00e-45	171.00
IUUC-Vvi-131387	Vitis vinifera	57.14	1.00e-43	167.00
IUUC-Xtr-132450	Xenopus tropicalis	64.20	2.00e-60	222.00
IUUC-Xma-133016	Xiphophorus maculatus	65.03	1.00e-61	226.00
IUUC-Yli-134379	Yarrowia lipolytica	65.03	1.00e-65	239.00
IUUC-Zma-135764	Zea mays	52.35	2.00e-42	163.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence