iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090139

Ensembl Protein ID

ENSOARP00000004794.1

UniProt Accession

W5P2Z4; W5P2Z4_SHEEP

Genbank Protein ID

ENSOARP00000004794

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01060516

Gene Name

EED

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000004477.1	ENSOART00000004875.1	ENSOARP00000004794.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-15	55.6	150	187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
           gH + ++ l+f   d +ll+s s D+ +++W++ t++l
   Q: 150  GHGNAINELKFhpRDpNLLLSVSKDHALRLWNIQTDTL 187
           899*********9888****************999876 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

DDAVSIESGT NTERPDTPTN TPNAPGRKSW GKGKWKSKKC KYSFKCVNSL KEDHNQPLFG 60
VQFNWHSKEG DPLVFATVGS NRVTLYECHS QGEIRLLQSY VDADADENFY TCAWTYDSNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGATGCTG TCAGTATAGA AAGCGGTACC AACACAGAAC GCCCTGATAC ACCTACAAAT 60
ACGCCAAATG CACCTGGAAG GAAGAGTTGG GGGAAGGGAA AATGGAAATC AAAGAAATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0035098--C:ESC/E(Z) complex
GO:0045120--C:pronucleus
GO:0001739--C:sex chromatin
GO:0003682--F:chromatin binding
GO:0042054--F:histone methyltransferase activity
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0061087--P:positive regulation of histone H3-K27 methylation
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0006349--P:regulation of gene expression by genetic imprinting

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000689	Aegilops tauschii	41.01	2.00e-75	276.00
IUUC-Aml-001510	Ailuropoda melanoleuca	99.01	0.00e+00	786.00
IUUC-Atr-002496	Amborella trichopoda	40.40	6.00e-69	254.00
IUUC-Apl-003768	Anas platyrhynchos	98.26	0.00e+00	783.00
IUUC-Aca-004382	Anolis carolinensis	98.26	0.00e+00	786.00
IUUC-Aly-005980	Arabidopsis lyrata	40.71	3.00e-76	278.00
IUUC-Ath-006579	Arabidopsis thaliana	40.71	3.00e-76	278.00
IUUC-Ame-010987	Astyanax mexicanus	94.04	0.00e+00	752.00
IUUC-Bta-013432	Bos taurus	99.75	0.00e+00	799.00
IUUC-Bci-013970	Botrytis cinerea	33.33	4.00e-30	126.00
IUUC-Bdi-014553	Brachypodium distachyon	43.14	2.00e-77	282.00
IUUC-Bol-016522	Brassica oleracea	40.22	2.00e-75	276.00
IUUC-Bra-017137	Brassica rapa	40.22	1.00e-75	276.00
IUUC-Cel-018494	Caenorhabditis elegans	24.36	2.00e-29	123.00
IUUC-Cja-019066	Callithrix jacchus	99.75	0.00e+00	800.00
IUUC-Cfa-021261	Canis familiaris	99.75	0.00e+00	799.00
IUUC-Cpo-022375	Cavia porcellus	93.55	0.00e+00	734.00
IUUC-Csa-024005	Chlorocebus sabaeus	99.75	0.00e+00	799.00
IUUC-Cho-024881	Choloepus hoffmanni	85.26	3.00e-142	498.00
IUUC-Cin-025697	Ciona intestinalis	61.06	4.00e-141	494.00
IUUC-Csv-026221	Ciona savignyi	63.31	2.00e-144	505.00
IUUC-Cgl-026519	Colletotrichum gloeosporioides	26.24	2.00e-24	106.00
IUUC-Cne-026877	Cryptococcus neoformans	30.20	2.00e-27	117.00
IUUC-Cme-027353	Cyanidioschyzon merolae	44.83	8.00e-33	135.00
IUUC-Dre-028346	Danio rerio	92.06	0.00e+00	741.00
IUUC-Dno-029319	Dasypus novemcinctus	98.76	0.00e+00	791.00
IUUC-Dor-030746	Dipodomys ordii	80.82	6.00e-171	593.00
IUUC-Dse-031324	Dothistroma septosporum	26.55	3.00e-27	116.00
IUUC-Dme-032029	Drosophila melanogaster	60.82	4.00e-137	481.00
IUUC-Ete-032880	Echinops telfairi	78.60	4.00e-112	397.00
IUUC-Eca-034272	Equus caballus	99.75	0.00e+00	795.00
IUUC-Eeu-035303	Erinaceus europaeus	92.52	0.00e+00	767.00
IUUC-Fca-036008	Felis catus	99.75	0.00e+00	797.00
IUUC-Fal-037577	Ficedula albicollis	98.26	0.00e+00	783.00
IUUC-Fso-038294	Fusarium solani	24.66	8.00e-27	114.00
IUUC-Gmo-039008	Gadus morhua	90.84	0.00e+00	712.00
IUUC-Ggr-039894	Gaeumannomyces graminis	30.83	9.00e-25	108.00
IUUC-Gga-040859	Gallus gallus	98.26	0.00e+00	784.00
IUUC-Gac-041667	Gasterosteus aculeatus	88.61	0.00e+00	708.00
IUUC-Gma-043832	Glycine max	39.89	9.00e-75	273.00
IUUC-Ggo-045624	Gorilla gorilla	93.93	0.00e+00	785.00
IUUC-Hsa-046505	Homo sapiens	99.75	0.00e+00	799.00
IUUC-Hvu-047228	Hordeum vulgare	37.77	7.00e-33	132.00
IUUC-Itr-048381	Ictidomys tridecemlineatus	99.75	0.00e+00	799.00
IUUC-Lch-050492	Latimeria chalumnae	96.77	0.00e+00	773.00
IUUC-Lpe-050807	Leersia perrieri	37.78	3.00e-72	265.00
IUUC-Loc-052361	Lepisosteus oculatus	94.32	0.00e+00	759.00
IUUC-Lma-053058	Leptosphaeria maculans	28.15	3.00e-21	96.30
IUUC-Laf-053941	Loxodonta africana	91.56	0.00e+00	748.00
IUUC-Mcc-055518	Macaca mulatta	93.93	0.00e+00	785.00
IUUC-Mor-056944	Magnaporthe oryzae	26.87	3.00e-27	116.00
IUUC-Mtr-058716	Medicago truncatula	42.08	4.00e-71	261.00
IUUC-Mga-059469	Meleagris gallopavo	98.26	0.00e+00	784.00
IUUC-Mmr-061026	Microcebus murinus	93.69	0.00e+00	784.00
IUUC-Mdo-062346	Monodelphis domestica	98.51	0.00e+00	789.00
IUUC-Mmu-063785	Mus musculus	99.75	0.00e+00	799.00
IUUC-Mac-064681	Musa acuminata	41.03	2.00e-79	289.00
IUUC-Mpu-066862	Mustela putorius furo	99.75	0.00e+00	799.00
IUUC-Mlu-067103	Myotis lucifugus	92.80	0.00e+00	725.00
IUUC-Ncr-068782	Neurospora crassa	30.89	7.00e-26	112.00
IUUC-Nle-069472	Nomascus leucogenys	99.75	0.00e+00	799.00
IUUC-Opr-070376	Ochotona princeps	96.51	5.00e-125	441.00
IUUC-Ont-071513	Oreochromis niloticus	93.55	0.00e+00	770.00
IUUC-Oan-073202	Ornithorhynchus anatinus	99.01	0.00e+00	788.00
IUUC-Ocu-074012	Oryctolagus cuniculus	99.50	0.00e+00	798.00
IUUC-Oba-075030	Oryza barthii	42.51	5.00e-80	291.00
IUUC-Obr-076895	Oryza brachyantha	41.98	7.00e-78	284.00
IUUC-Ogl-077522	Oryza glaberrima	42.78	4.00e-79	288.00
IUUC-Ogu-078250	Oryza glumaepatula	38.84	8.00e-68	251.00
IUUC-Oin-079886	Oryza indica	42.23	2.00e-79	288.00
IUUC-Olo-080238	Oryza longistaminata	42.51	6.00e-80	290.00
IUUC-Ome-081204	Oryza meridionalis	39.37	1.00e-66	246.00
IUUC-Oni-082388	Oryza nivara	38.63	4.00e-70	259.00
IUUC-Opu-083537	Oryza punctata	42.09	3.00e-78	285.00
IUUC-Oru-084863	Oryza rufipogon	39.12	2.00e-68	253.00
IUUC-Osa-085622	Oryza sativa	42.43	4.00e-80	291.00
IUUC-Ola-087426	Oryzias latipes	91.23	0.00e+00	751.00
IUUC-Olu-087788	Ostreococcus lucimarinus	29.89	4.00e-44	171.00
IUUC-Oga-088228	Otolemur garnettii	99.75	0.00e+00	799.00
IUUC-Pan-092874	Papio anubis	99.62	1.00e-157	548.00
IUUC-Psi-093927	Pelodiscus sinensis	98.26	0.00e+00	784.00
IUUC-Pma-094740	Petromyzon marinus	87.27	1.00e-135	475.00
IUUC-Pno-095072	Phaeosphaeria nodorum	27.43	3.00e-20	92.40
IUUC-Ppa-095871	Physcomitrella patens	39.02	2.00e-72	265.00
IUUC-Pfo-097208	Poecilia formosa	93.80	0.00e+00	773.00
IUUC-Pab-097658	Pongo abelii	99.75	0.00e+00	799.00
IUUC-Pop-098930	Populus trichocarpa	41.30	4.00e-78	284.00
IUUC-Ppe-101807	Prunus persica	40.65	5.00e-76	277.00
IUUC-Pva-103191	Pteropus vampyrus	83.64	0.00e+00	679.00
IUUC-Pgr-103619	Puccinia graminis	25.87	1.00e-18	87.40
IUUC-Pte-104406	Pyrenophora teres	29.19	2.00e-28	120.00
IUUC-Pyt-104821	Pyrenophora triticirepentis	27.27	3.00e-23	102.00
IUUC-Rno-105854	Rattus norvegicus	99.75	0.00e+00	799.00
IUUC-Sha-107426	Sarcophilus harrisii	98.51	0.00e+00	788.00
IUUC-Smo-109638	Selaginella moellendorffii	40.17	4.00e-75	274.00
IUUC-Sit-110481	Setaria italica	41.85	3.00e-78	285.00
IUUC-Sly-111464	Solanum lycopersicum	39.89	3.00e-75	275.00
IUUC-Stu-112910	Solanum tuberosum	39.89	4.00e-75	275.00
IUUC-Sar-113754	Sorex araneus	91.91	0.00e+00	654.00
IUUC-Sbi-114023	Sorghum bicolor	42.13	2.00e-79	289.00
IUUC-Ssc-115386	Sus scrofa	99.75	0.00e+00	799.00
IUUC-Tgu-117123	Taeniopygia guttata	98.01	0.00e+00	785.00
IUUC-Tru-117720	Takifugu rubripes	89.88	0.00e+00	753.00
IUUC-Tsy-119584	Tarsius syrichta	93.93	0.00e+00	784.00
IUUC-Tni-119695	Tetraodon nigroviridis	93.55	0.00e+00	771.00
IUUC-Tca-121787	Theobroma cacao	41.58	1.00e-77	283.00
IUUC-Tvi-122409	Trichoderma virens	25.13	2.00e-22	100.00
IUUC-Tae-124454	Triticum aestivum	41.01	2.00e-75	276.00
IUUC-Tme-126906	Tuber melanosporum	30.00	9.00e-35	141.00
IUUC-Tbe-127557	Tupaia belangeri	92.46	0.00e+00	678.00
IUUC-Vda-129774	Verticillium dahliae	25.15	5.00e-21	95.50
IUUC-Vpa-130256	Vicugna pacos	84.81	0.00e+00	684.00
IUUC-Vvi-131201	Vitis vinifera	41.58	2.00e-76	279.00
IUUC-Xtr-132206	Xenopus tropicalis	95.29	0.00e+00	768.00
IUUC-Xma-134102	Xiphophorus maculatus	93.80	0.00e+00	773.00
IUUC-Zma-135593	Zea mays	42.70	7.00e-80	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence