iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092212

Ensembl Protein ID

ENSPANP00000017416.1

UniProt Accession

A9X1C6; WDR76_PAPAN

Genbank Protein ID

ABY40821.1

Protein Name

WD repeat-containing protein 76

Genbank Nucleotide ID

DP000543

Gene Name

WDR76

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000018062.1	ENSPANT00000007579.1	ENSPANP00000017416.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-12	47.3	359	389

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWD 29
           H+ +v+cl f   +  +++s s+Dgt+++ D
   Q: 359  HSQPVSCLYFspaNPAHILSLSYDGTLRCGD 389
           9**********963399**********9855 PP

Organism

Papio anubis

Functional Description
(View)

Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

Protein Sequence
(Fasta)

MSRSGAAAEK ADSRQRPQMK VNEYKENQNI AYVSLRPVQT TVLIKTAKVY LAPFSLSNYQ 60
LDQLMCPKSL LEKNSNNEVA CKKTKIKKTC RRIIPPKMKT TSSKSESTLQ NSASAVHTES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAGGT CGGGCGCGGC GGCTGAGAAG GCGGACTCCA GACAGCGACC CCAGATGAAG 60
GTGAGAAACG GATCGGTGCT TCCAGGTGTG CGCCTGCTTC GGTTTTTGTG AGGGTTATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR033052--Cmr1/WDR76
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0006974--P:cellular response to DNA damage stimulus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002605	Amborella trichopoda	26.88	6.00e-25	108.00
IUUC-Apl-003441	Anas platyrhynchos	52.88	1.00e-139	489.00
IUUC-Aca-004241	Anolis carolinensis	57.97	7.00e-144	503.00
IUUC-Aly-005444	Arabidopsis lyrata	26.65	4.00e-26	112.00
IUUC-Ath-007550	Arabidopsis thaliana	26.27	2.00e-25	110.00
IUUC-Ago-007715	Ashbya gossypii	23.26	1.00e-14	74.30
IUUC-Acl-008370	Aspergillus clavatus	24.21	6.00e-29	122.00
IUUC-Afl-008586	Aspergillus flavus	26.53	4.00e-32	132.00
IUUC-Afu-008907	Aspergillus fumigatus	26.26	1.00e-30	127.00
IUUC-Ani-009415	Aspergillus nidulans	25.54	1.00e-27	117.00
IUUC-Ang-009597	Aspergillus niger	25.00	7.00e-10	58.50
IUUC-Aor-010197	Aspergillus oryzae	26.53	2.00e-32	133.00
IUUC-Ate-010280	Aspergillus terreus	25.46	3.00e-31	129.00
IUUC-Bgr-012236	Blumeria graminis	25.34	9.00e-24	104.00
IUUC-Bta-013059	Bos taurus	78.22	0.00e+00	920.00
IUUC-Bci-013796	Botrytis cinerea	26.60	1.00e-27	117.00
IUUC-Bdi-015040	Brachypodium distachyon	28.74	2.00e-19	90.50
IUUC-Bol-015202	Brassica oleracea	26.40	1.00e-22	101.00
IUUC-Bra-018032	Brassica rapa	25.31	5.00e-22	99.40
IUUC-Cja-019043	Callithrix jacchus	92.19	0.00e+00	1078.00
IUUC-Cfa-021103	Canis familiaris	80.89	0.00e+00	961.00
IUUC-Cpo-021508	Cavia porcellus	73.61	0.00e+00	870.00
IUUC-Cre-022967	Chlamydomonas reinhardtii	35.35	3.00e-10	60.10
IUUC-Csa-023555	Chlorocebus sabaeus	98.87	0.00e+00	1010.00
IUUC-Cho-024931	Choloepus hoffmanni	64.12	2.00e-145	508.00
IUUC-Cin-025651	Ciona intestinalis	33.63	2.00e-59	223.00
IUUC-Cgl-026604	Colletotrichum gloeosporioides	24.93	6.00e-28	119.00
IUUC-Cne-027093	Cryptococcus neoformans	26.88	2.00e-20	94.40
IUUC-Cme-027238	Cyanidioschyzon merolae	26.36	9.00e-20	91.70
IUUC-Dre-027441	Danio rerio	36.70	2.00e-88	319.00
IUUC-Dno-029575	Dasypus novemcinctus	79.01	0.00e+00	931.00
IUUC-Dor-030554	Dipodomys ordii	72.09	0.00e+00	644.00
IUUC-Dse-031299	Dothistroma septosporum	25.85	1.00e-29	124.00
IUUC-Ete-032716	Echinops telfairi	62.32	0.00e+00	644.00
IUUC-Eca-034027	Equus caballus	79.67	0.00e+00	801.00
IUUC-Eeu-035234	Erinaceus europaeus	84.71	1.00e-79	290.00
IUUC-Fca-035892	Felis catus	81.46	0.00e+00	954.00
IUUC-Fal-036986	Ficedula albicollis	50.32	3.00e-121	428.00
IUUC-Fox-037750	Fusarium oxysporum	25.07	4.00e-27	115.00
IUUC-Fso-038198	Fusarium solani	23.53	5.00e-20	92.40
IUUC-Gga-040479	Gallus gallus	51.21	5.00e-100	358.00
IUUC-Gac-042043	Gasterosteus aculeatus	43.83	3.00e-91	328.00
IUUC-Gma-042915	Glycine max	25.21	4.00e-28	119.00
IUUC-Ggo-045290	Gorilla gorilla	96.49	0.00e+00	1140.00
IUUC-Hsa-047021	Homo sapiens	96.65	0.00e+00	1140.00
IUUC-Hvu-047193	Hordeum vulgare	28.27	3.00e-17	82.80
IUUC-Itr-047914	Ictidomys tridecemlineatus	79.97	0.00e+00	959.00
IUUC-Kpa-049275	Komagataella pastoris	22.76	3.00e-17	83.20
IUUC-Lch-049718	Latimeria chalumnae	55.16	7.00e-146	510.00
IUUC-Lpe-051708	Leersia perrieri	27.73	9.00e-16	78.20
IUUC-Loc-052565	Lepisosteus oculatus	46.23	1.00e-111	396.00
IUUC-Lma-053276	Leptosphaeria maculans	26.65	1.00e-31	131.00
IUUC-Laf-053970	Loxodonta africana	76.07	0.00e+00	890.00
IUUC-Mcc-054740	Macaca mulatta	98.40	0.00e+00	1032.00
IUUC-Meu-056546	Macropus eugenii	62.92	9.00e-73	268.00
IUUC-Mtr-058451	Medicago truncatula	26.58	8.00e-33	134.00
IUUC-Mla-059117	Melampsora laricipopulina	25.26	2.00e-19	90.50
IUUC-Mga-059328	Meleagris gallopavo	48.31	6.00e-102	363.00
IUUC-Mvi-060555	Microbotryum violaceum	26.78	1.00e-20	95.10
IUUC-Mmr-061520	Microcebus murinus	80.85	0.00e+00	981.00
IUUC-Mdo-062812	Monodelphis domestica	58.72	0.00e+00	667.00
IUUC-Mmu-064011	Mus musculus	68.84	0.00e+00	711.00
IUUC-Mpu-066486	Mustela putorius furo	79.65	0.00e+00	940.00
IUUC-Mlu-067721	Myotis lucifugus	76.75	0.00e+00	746.00
IUUC-Nfi-068314	Neosartorya fischeri	26.65	5.00e-30	125.00
IUUC-Ncr-068896	Neurospora crassa	27.15	1.00e-27	117.00
IUUC-Nle-069369	Nomascus leucogenys	96.33	0.00e+00	1167.00
IUUC-Opr-070975	Ochotona princeps	75.12	0.00e+00	826.00
IUUC-Ont-072528	Oreochromis niloticus	42.86	7.00e-98	350.00
IUUC-Oan-072955	Ornithorhynchus anatinus	60.73	2.00e-142	498.00
IUUC-Ocu-074561	Oryctolagus cuniculus	80.65	0.00e+00	908.00
IUUC-Oba-074982	Oryza barthii	28.12	4.00e-21	96.70
IUUC-Ogl-077685	Oryza glaberrima	27.58	2.00e-21	97.10
IUUC-Ogu-078331	Oryza glumaepatula	27.58	2.00e-21	97.10
IUUC-Oin-079507	Oryza indica	29.89	6.00e-21	95.90
IUUC-Olo-080604	Oryza longistaminata	29.65	5.00e-17	82.00
IUUC-Ome-081816	Oryza meridionalis	26.41	3.00e-19	89.70
IUUC-Oni-082051	Oryza nivara	27.58	3.00e-21	95.90
IUUC-Opu-083372	Oryza punctata	28.67	2.00e-19	90.10
IUUC-Oru-084578	Oryza rufipogon	27.58	2.00e-21	97.10
IUUC-Osa-086177	Oryza sativa	27.58	2.00e-21	97.10
IUUC-Ola-087208	Oryzias latipes	42.83	7.00e-93	334.00
IUUC-Olu-087680	Ostreococcus lucimarinus	29.52	2.00e-29	123.00
IUUC-Oga-088104	Otolemur garnettii	81.39	0.00e+00	964.00
IUUC-Oar-090157	Ovis aries	79.84	0.00e+00	934.00
IUUC-Ptr-091615	Pan troglodytes	96.01	0.00e+00	1137.00
IUUC-Psi-092950	Pelodiscus sinensis	52.83	3.00e-161	561.00
IUUC-Pma-094625	Petromyzon marinus	31.97	1.00e-26	113.00
IUUC-Pno-094824	Phaeosphaeria nodorum	27.60	6.00e-36	145.00
IUUC-Pfo-096922	Poecilia formosa	42.02	2.00e-101	363.00
IUUC-Pab-097591	Pongo abelii	96.49	0.00e+00	1145.00
IUUC-Pop-099337	Populus trichocarpa	24.52	1.00e-24	107.00
IUUC-Pca-101025	Procavia capensis	64.14	0.00e+00	708.00
IUUC-Ppe-101256	Prunus persica	26.61	4.00e-17	82.80
IUUC-Pva-102453	Pteropus vampyrus	73.84	0.00e+00	818.00
IUUC-Pgr-103436	Puccinia graminis	24.88	9.00e-15	75.10
IUUC-Ptt-103899	Puccinia triticina	27.03	3.00e-16	79.70
IUUC-Pte-104258	Pyrenophora teres	27.99	1.00e-35	144.00
IUUC-Pyt-104625	Pyrenophora triticirepentis	28.53	2.00e-36	146.00
IUUC-Rno-104843	Rattus norvegicus	69.39	0.00e+00	812.00
IUUC-Sce-106189	Saccharomyces cerevisiae	25.54	1.00e-18	87.80
IUUC-Sha-106672	Sarcophilus harrisii	60.20	0.00e+00	681.00
IUUC-Smo-109660	Selaginella moellendorffii	29.29	2.00e-23	102.00
IUUC-Sit-109704	Setaria italica	27.00	5.00e-20	92.40
IUUC-Sly-111853	Solanum lycopersicum	24.85	3.00e-26	112.00
IUUC-Stu-112482	Solanum tuberosum	23.33	6.00e-23	102.00
IUUC-Sar-113537	Sorex araneus	55.61	3.00e-99	355.00
IUUC-Sbi-114517	Sorghum bicolor	29.61	1.00e-16	81.30
IUUC-Sre-114960	Sporisorium reilianum	28.03	9.00e-09	55.50
IUUC-Ssc-115568	Sus scrofa	82.21	0.00e+00	972.00
IUUC-Tgu-117276	Taeniopygia guttata	48.32	3.00e-115	408.00
IUUC-Tru-117559	Takifugu rubripes	51.20	1.00e-35	141.00
IUUC-Tsy-119234	Tarsius syrichta	64.08	0.00e+00	682.00
IUUC-Tni-120358	Tetraodon nigroviridis	42.74	2.00e-95	342.00
IUUC-Tca-121273	Theobroma cacao	24.70	1.00e-24	108.00
IUUC-Tre-121932	Trichoderma reesei	26.45	1.00e-31	130.00
IUUC-Tvi-122567	Trichoderma virens	27.50	2.00e-34	140.00
IUUC-Tae-123506	Triticum aestivum	27.64	2.00e-13	70.50
IUUC-Tme-126958	Tuber melanosporum	25.35	4.00e-16	79.00
IUUC-Tbe-127425	Tupaia belangeri	84.96	0.00e+00	743.00
IUUC-Ttr-129123	Tursiops truncatus	71.90	0.00e+00	803.00
IUUC-Uma-129495	Ustilago maydis	32.03	8.00e-11	62.40
IUUC-Vda-129981	Verticillium dahliae	26.16	1.00e-29	124.00
IUUC-Vpa-130437	Vicugna pacos	74.44	0.00e+00	837.00
IUUC-Vvi-131430	Vitis vinifera	23.28	1.00e-22	100.00
IUUC-Xtr-132670	Xenopus tropicalis	52.75	5.00e-128	451.00
IUUC-Xma-133375	Xiphophorus maculatus	41.91	1.00e-99	357.00
IUUC-Yli-134341	Yarrowia lipolytica	25.13	4.00e-19	89.40
IUUC-Zma-135413	Zea mays	28.77	6.00e-21	95.50

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence