iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134510

Ensembl Protein ID

CAG83255

UniProt Accession

Q6CEB0; Q6CEB0_YARLI

Genbank Protein ID

CAG83255.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CR382128

Gene Name

YALI0_B17072g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_B17072g	CAG83255	CAG83255

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.10e-55	185.1	299	756
UBD/Alpha-Helix/UBA	1.90e-20	70.8	632	669

Active Site

Position(s)	Description	Evidence
308	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
718	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel..........w....kskkkavsprellkalkkeaeefsgy 87
           tG++NlgN+CY+NS++Q+++++p ++++++   ++++ ++    p ++ +++++kl   l          +     s ++ + p +l++ l+k ++efs++
   Q: 299  TGMNNLGNSCYLNSAMQVIFSLPAFQKQFNV--PQQFIAD----PINSHVTQFRKLADGLlsgryavpdvYddseVSYQRGIRPFALKTLLGKGHPEFSTN 393
           7*****************************9..7777654....5667777777777777444444444414344666669******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke... 185
           +qqDa Ef+a++ d +++++                             ++   ++d+F++q++++++cl+c++v  ++e    ls+pvp +e+ ++    
   Q: 394  RQQDAFEFWAHVTDIIDNKI-----------------------------EGGRALTDIFRFQTEKRLQCLSCNKVRYTKEAQENLSVPVPIREKGEQDgkt 465
           ********************.............................567889***********************************99888777899 PP
   S: 186  .....slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke....... 274
                +l++cL ++t +++ +    y+c kc +k  a+ + k+ +lP+vL+l+  Rf  + +++++ k++ ++++ ++L+l+ + +  +++++e       
   Q: 466  vyedvELSECLIKYTGAQTTD----YSC-KCGGKE-ASVSNKFASLPDVLVLNSTRF--QIKNWVPMKVDVNLNVDENLNLDDYISPGKQDNEEelpedea 558
           99999***************9....777.788876.99999****************..5577**********************9944444446667777 PP
   S: 275  ..................................................................................................... 274
                                                                                                                
   Q: 559  gegnssgwtanetaveilsamgfptvrcekalyhtgnsdpdaamnwlfshmedadideplvidssvpssgstdnsaaiaqvaemgftpnqarkalrecsgn 659
           77777777777777777777777777777777777777777777777777777777777777777777777778888888888888888888888888888 PP
   S: 275  ......................................kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
                                                 +++YeL+++++H+G s++ GHYvayvk+ +gkW+lf+D+kV +++ e++++     aYv++++
   Q: 660  vemavawlfenpadegeeesaavatevassgpvgytekPHNYELTGIICHKGtSVHAGHYVAYVKK-DGKWILFNDEKVVSSSVEDMKK----LAYVYVFQ 755
           88888888888888888899999999999999999999****************************.9*******************99....89999998 PP
   S: 337  r 337
           r
   Q: 756  R 756
           7 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLld 40
           ++ +++q  eMGF++++a++aLr++++n+e+Av++L++
   Q: 632  NSAAIAQVAEMGFTPNQARKALRECSGNVEMAVAWLFE 669
           56789999****************************97 PP

Organism

Yarrowia lipolytica

Protein Sequence
(Fasta)

MDPYTEAAIN LQPPNGRPVH KDDCAYSFDT PDLQGGLDVC LSCFQASSAH ANQDYTKLHF 60
DNTGHSYFAT VHKKRKAKAR SDENAPKRLA IEAHKEEDDW DTQWGVKLVT AVGSEKLDET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCCAT ACACCGAAGC CGCCATCAAT TTACAGCCTC CCAACGGCAG ACCCGTGCAC 60
AAGGACGATT GTGCATACTC CTTCGACACT CCCGATCTTC AAGGCGGACT CGATGTCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

yli:YALI0B17072g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	31.22	3.00e-95	340.00
IUUC-Aml-002104	Ailuropoda melanoleuca	35.53	5.00e-138	483.00
IUUC-Atr-002580	Amborella trichopoda	33.22	1.00e-112	398.00
IUUC-Apl-003774	Anas platyrhynchos	35.83	2.00e-133	467.00
IUUC-Aca-005368	Anolis carolinensis	36.70	3.00e-140	490.00
IUUC-Aly-005727	Arabidopsis lyrata	34.49	5.00e-114	403.00
IUUC-Ath-006974	Arabidopsis thaliana	33.95	1.00e-112	398.00
IUUC-Ago-007890	Ashbya gossypii	31.95	1.00e-103	369.00
IUUC-Acl-008057	Aspergillus clavatus	43.45	1.00e-180	624.00
IUUC-Afl-008547	Aspergillus flavus	47.12	3.00e-168	582.00
IUUC-Afu-008805	Aspergillus fumigatus	42.41	3.00e-161	560.00
IUUC-Ani-009441	Aspergillus nidulans	42.53	4.00e-146	509.00
IUUC-Ang-009720	Aspergillus niger	45.68	2.00e-178	617.00
IUUC-Aor-010111	Aspergillus oryzae	44.83	0.00e+00	642.00
IUUC-Ate-010531	Aspergillus terreus	41.09	8.00e-150	521.00
IUUC-Ame-011470	Astyanax mexicanus	33.02	6.00e-120	423.00
IUUC-Bgr-012183	Blumeria graminis	43.62	5.00e-171	592.00
IUUC-Bta-013179	Bos taurus	35.38	3.00e-137	480.00
IUUC-Bci-013858	Botrytis cinerea	46.42	0.00e+00	677.00
IUUC-Bdi-014904	Brachypodium distachyon	34.82	7.00e-107	379.00
IUUC-Bol-015536	Brassica oleracea	34.78	2.00e-112	397.00
IUUC-Bra-017939	Brassica rapa	34.49	1.00e-112	398.00
IUUC-Cel-018625	Caenorhabditis elegans	30.26	5.00e-83	300.00
IUUC-Cja-019063	Callithrix jacchus	35.53	4.00e-137	479.00
IUUC-Cfa-020976	Canis familiaris	36.13	3.00e-140	490.00
IUUC-Cpo-022265	Cavia porcellus	36.36	5.00e-140	489.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	32.35	3.00e-77	281.00
IUUC-Csa-024177	Chlorocebus sabaeus	35.68	1.00e-122	431.00
IUUC-Cho-024702	Choloepus hoffmanni	34.21	4.00e-81	293.00
IUUC-Cin-025411	Ciona intestinalis	33.25	2.00e-111	394.00
IUUC-Csv-026347	Ciona savignyi	32.15	2.00e-109	387.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	45.43	9.00e-172	595.00
IUUC-Cne-026831	Cryptococcus neoformans	43.09	2.00e-165	573.00
IUUC-Cme-027335	Cyanidioschyzon merolae	33.03	2.00e-53	202.00
IUUC-Dre-027982	Danio rerio	34.08	1.00e-113	401.00
IUUC-Dno-029034	Dasypus novemcinctus	35.66	4.00e-138	483.00
IUUC-Dor-030479	Dipodomys ordii	37.88	3.00e-61	228.00
IUUC-Dse-031467	Dothistroma septosporum	43.66	4.00e-177	612.00
IUUC-Dme-032075	Drosophila melanogaster	34.28	4.00e-117	413.00
IUUC-Ete-032865	Echinops telfairi	32.90	1.00e-115	409.00
IUUC-Eca-034059	Equus caballus	35.38	5.00e-136	476.00
IUUC-Eeu-035304	Erinaceus europaeus	34.36	2.00e-124	437.00
IUUC-Fca-035515	Felis catus	35.50	5.00e-138	483.00
IUUC-Fal-037271	Ficedula albicollis	36.34	9.00e-129	452.00
IUUC-Fox-037745	Fusarium oxysporum	46.25	0.00e+00	654.00
IUUC-Fso-038158	Fusarium solani	45.21	0.00e+00	638.00
IUUC-Gmo-039071	Gadus morhua	35.62	1.00e-122	432.00
IUUC-Ggr-040098	Gaeumannomyces graminis	45.49	3.00e-172	597.00
IUUC-Gga-040635	Gallus gallus	36.15	2.00e-140	491.00
IUUC-Gac-042528	Gasterosteus aculeatus	34.75	2.00e-117	414.00
IUUC-Gma-043614	Glycine max	33.62	1.00e-111	395.00
IUUC-Ggo-044602	Gorilla gorilla	35.66	2.00e-138	484.00
IUUC-Hsa-045959	Homo sapiens	35.66	2.00e-138	484.00
IUUC-Hvu-047563	Hordeum vulgare	36.96	2.00e-102	364.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	35.61	2.00e-138	484.00
IUUC-Kpa-049156	Komagataella pastoris	40.00	5.00e-163	566.00
IUUC-Lch-049648	Latimeria chalumnae	35.91	6.00e-129	452.00
IUUC-Lpe-051523	Leersia perrieri	33.78	3.00e-108	384.00
IUUC-Loc-052072	Lepisosteus oculatus	33.49	4.00e-119	420.00
IUUC-Lma-053216	Leptosphaeria maculans	45.96	3.00e-176	611.00
IUUC-Laf-054327	Loxodonta africana	35.06	7.00e-136	476.00
IUUC-Mcc-055443	Macaca mulatta	35.66	2.00e-138	484.00
IUUC-Meu-056298	Macropus eugenii	35.25	5.00e-89	320.00
IUUC-Mor-057106	Magnaporthe oryzae	46.12	0.00e+00	638.00
IUUC-Mpo-057589	Magnaporthe poae	45.51	2.00e-176	610.00
IUUC-Mtr-058680	Medicago truncatula	35.23	9.00e-114	402.00
IUUC-Mla-058903	Melampsora laricipopulina	38.94	1.00e-145	508.00
IUUC-Mga-059669	Meleagris gallopavo	35.25	1.00e-129	455.00
IUUC-Mvi-060476	Microbotryum violaceum	42.57	5.00e-149	519.00
IUUC-Mmr-060575	Microcebus murinus	35.76	3.00e-139	487.00
IUUC-Mdo-062183	Monodelphis domestica	35.77	4.00e-135	473.00
IUUC-Mmu-063592	Mus musculus	35.86	1.00e-138	485.00
IUUC-Mac-065634	Musa acuminata	31.47	2.00e-99	354.00
IUUC-Mpu-066082	Mustela putorius furo	36.12	2.00e-140	491.00
IUUC-Mlu-067345	Myotis lucifugus	35.80	2.00e-136	478.00
IUUC-Nfi-068558	Neosartorya fischeri	43.95	4.00e-175	606.00
IUUC-Ncr-068960	Neurospora crassa	43.09	7.00e-170	588.00
IUUC-Nle-070173	Nomascus leucogenys	36.13	4.00e-140	489.00
IUUC-Opr-070556	Ochotona princeps	35.69	1.00e-138	485.00
IUUC-Ont-071502	Oreochromis niloticus	36.15	3.00e-122	430.00
IUUC-Oan-072959	Ornithorhynchus anatinus	43.56	3.00e-47	179.00
IUUC-Ocu-074861	Oryctolagus cuniculus	36.04	2.00e-139	487.00
IUUC-Oba-075109	Oryza barthii	33.88	2.00e-110	391.00
IUUC-Obr-076292	Oryza brachyantha	34.57	9.00e-107	379.00
IUUC-Ogl-077065	Oryza glaberrima	34.57	1.00e-114	405.00
IUUC-Ogu-078776	Oryza glumaepatula	33.54	1.00e-110	392.00
IUUC-Oin-080048	Oryza indica	34.25	6.00e-114	402.00
IUUC-Olo-080711	Oryza longistaminata	32.47	5.00e-99	353.00
IUUC-Ome-081506	Oryza meridionalis	33.20	7.00e-102	362.00
IUUC-Oni-082320	Oryza nivara	33.05	2.00e-108	385.00
IUUC-Opu-083801	Oryza punctata	33.80	3.00e-105	374.00
IUUC-Oru-085139	Oryza rufipogon	32.93	5.00e-108	383.00
IUUC-Osa-085713	Oryza sativa	34.70	5.00e-116	409.00
IUUC-Ola-086951	Oryzias latipes	35.14	2.00e-116	411.00
IUUC-Olu-087822	Ostreococcus lucimarinus	32.56	5.00e-97	347.00
IUUC-Oga-088625	Otolemur garnettii	35.50	2.00e-138	484.00
IUUC-Oar-089995	Ovis aries	35.26	1.00e-136	478.00
IUUC-Ptr-090640	Pan troglodytes	36.71	2.00e-142	498.00
IUUC-Pan-091974	Papio anubis	35.65	1.00e-138	484.00
IUUC-Psi-093957	Pelodiscus sinensis	35.50	5.00e-139	486.00
IUUC-Pma-094242	Petromyzon marinus	38.26	3.00e-69	253.00
IUUC-Pno-094835	Phaeosphaeria nodorum	45.29	5.00e-162	562.00
IUUC-Ppa-095901	Physcomitrella patens	34.34	2.00e-116	410.00
IUUC-Pfo-097148	Poecilia formosa	36.15	1.00e-120	425.00
IUUC-Pab-098068	Pongo abelii	33.29	2.00e-119	421.00
IUUC-Pop-098943	Populus trichocarpa	34.53	2.00e-107	381.00
IUUC-Pca-100738	Procavia capensis	36.59	2.00e-101	361.00
IUUC-Ppe-101315	Prunus persica	33.82	1.00e-102	365.00
IUUC-Pva-102154	Pteropus vampyrus	35.18	7.00e-134	469.00
IUUC-Pgr-103343	Puccinia graminis	38.74	9.00e-123	432.00
IUUC-Ptt-103928	Puccinia triticina	35.31	4.00e-117	413.00
IUUC-Pte-104306	Pyrenophora teres	45.02	1.00e-162	564.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	44.79	6.00e-165	572.00
IUUC-Rno-105801	Rattus norvegicus	36.09	2.00e-139	487.00
IUUC-Sce-106304	Saccharomyces cerevisiae	34.08	1.00e-112	399.00
IUUC-Sha-107635	Sarcophilus harrisii	35.71	1.00e-135	475.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	40.91	1.00e-158	551.00
IUUC-Spo-108144	Schizosaccharomyces pombe	39.01	4.00e-157	546.00
IUUC-Smo-108703	Selaginella moellendorffii	34.63	2.00e-107	381.00
IUUC-Sit-110728	Setaria italica	35.11	6.00e-115	406.00
IUUC-Sly-111523	Solanum lycopersicum	34.80	8.00e-118	416.00
IUUC-Sar-113733	Sorex araneus	36.34	1.00e-60	225.00
IUUC-Sbi-114419	Sorghum bicolor	34.91	7.00e-114	402.00
IUUC-Sre-115225	Sporisorium reilianum	42.06	1.00e-160	558.00
IUUC-Ssc-115686	Sus scrofa	35.73	4.00e-138	483.00
IUUC-Tgu-117346	Taeniopygia guttata	36.34	4.00e-136	476.00
IUUC-Tru-118350	Takifugu rubripes	33.53	2.00e-119	421.00
IUUC-Tsy-119278	Tarsius syrichta	30.14	2.00e-93	335.00
IUUC-Tni-120658	Tetraodon nigroviridis	34.08	2.00e-114	404.00
IUUC-Tca-121585	Theobroma cacao	33.29	2.00e-105	374.00
IUUC-Tre-122043	Trichoderma reesei	44.80	1.00e-178	617.00
IUUC-Tvi-122303	Trichoderma virens	44.40	0.00e+00	627.00
IUUC-Tae-123798	Triticum aestivum	34.41	2.00e-113	401.00
IUUC-Tur-126732	Triticum urartu	31.74	5.00e-100	356.00
IUUC-Tme-126909	Tuber melanosporum	45.63	6.00e-180	622.00
IUUC-Tbe-127261	Tupaia belangeri	31.51	9.00e-52	196.00
IUUC-Ttr-129119	Tursiops truncatus	38.46	3.00e-63	234.00
IUUC-Uma-129599	Ustilago maydis	41.46	3.00e-166	577.00
IUUC-Vda-129688	Verticillium dahliae	46.03	0.00e+00	629.00
IUUC-Vpa-130170	Vicugna pacos	36.47	6.00e-50	190.00
IUUC-Vvi-131116	Vitis vinifera	33.13	9.00e-107	379.00
IUUC-Xtr-131953	Xenopus tropicalis	35.38	4.00e-128	450.00
IUUC-Xma-133837	Xiphophorus maculatus	36.03	2.00e-120	424.00
IUUC-Zma-135786	Zea mays	33.90	6.00e-108	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence