iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048233

Ensembl Protein ID

ENSSTOP00000010729.2

UniProt Accession

I3MIA4; I3MIA4_ICTTR

Genbank Protein ID

ENSSTOP00000010729

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01114452

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000011958.2	ENSSTOT00000011959.2	ENSSTOP00000010729.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	78.66	8.00e-179	624.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MDRSKENCVS GPVKATVPHG EGPKRVLVTQ HIPSQNPLST SSGQAQRILC PSNSSQRVPL 60
HAQKLVSSQK LGQKQLQAAS IPRPVSRPVN NTQKSEQSQP SGPGNNPERE LASKQKNEDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGAT CTAAAGAAAA CTGTGTTTCA GGGCCCGTTA AGGTAAATTG AATAGTTTGC 60
AATCATATTT ATAAAACTCA CATGGAGATC AGGCTGGCAT CTGAAATTTT TCTCAACTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	53.09	4.00e-78	284.00
IUUC-Aml-001426	Ailuropoda melanoleuca	78.04	2.00e-175	607.00
IUUC-Atr-002453	Amborella trichopoda	54.17	3.00e-82	298.00
IUUC-Apl-003626	Anas platyrhynchos	59.07	5.00e-121	427.00
IUUC-Aca-004602	Anolis carolinensis	57.48	4.00e-114	404.00
IUUC-Aly-005878	Arabidopsis lyrata	54.28	3.00e-80	291.00
IUUC-Ath-007117	Arabidopsis thaliana	55.02	6.00e-81	293.00
IUUC-Acl-008199	Aspergillus clavatus	45.62	1.00e-63	236.00
IUUC-Afl-008419	Aspergillus flavus	44.89	7.00e-63	233.00
IUUC-Afu-008751	Aspergillus fumigatus	41.90	9.00e-64	236.00
IUUC-Ani-009181	Aspergillus nidulans	43.43	1.00e-66	246.00
IUUC-Ang-009787	Aspergillus niger	47.06	3.00e-63	235.00
IUUC-Aor-009980	Aspergillus oryzae	44.89	7.00e-63	233.00
IUUC-Ate-010286	Aspergillus terreus	44.06	6.00e-63	234.00
IUUC-Ame-010849	Astyanax mexicanus	59.67	1.00e-98	353.00
IUUC-Bgr-012110	Blumeria graminis	46.62	4.00e-64	238.00
IUUC-Bta-013474	Bos taurus	75.68	2.00e-171	595.00
IUUC-Bci-013756	Botrytis cinerea	44.34	3.00e-71	261.00
IUUC-Bdi-014257	Brachypodium distachyon	52.13	2.00e-78	285.00
IUUC-Bol-016310	Brassica oleracea	53.28	3.00e-78	284.00
IUUC-Bra-017438	Brassica rapa	53.65	3.00e-80	291.00
IUUC-Cel-018157	Caenorhabditis elegans	50.35	1.00e-77	282.00
IUUC-Cja-019282	Callithrix jacchus	77.56	2.00e-169	588.00
IUUC-Cfa-020162	Canis familiaris	75.71	2.00e-171	594.00
IUUC-Cpo-021764	Cavia porcellus	75.31	4.00e-167	580.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	51.35	4.00e-81	294.00
IUUC-Csa-023694	Chlorocebus sabaeus	77.17	1.00e-159	555.00
IUUC-Cho-024350	Choloepus hoffmanni	72.96	1.00e-77	281.00
IUUC-Cin-025542	Ciona intestinalis	58.80	3.00e-89	321.00
IUUC-Csv-025873	Ciona savignyi	57.84	3.00e-91	327.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	41.74	5.00e-66	244.00
IUUC-Cne-026928	Cryptococcus neoformans	50.19	7.00e-71	260.00
IUUC-Cme-027336	Cyanidioschyzon merolae	60.23	1.00e-90	326.00
IUUC-Dre-028198	Danio rerio	53.08	6.00e-102	363.00
IUUC-Dno-029928	Dasypus novemcinctus	73.64	1.00e-154	538.00
IUUC-Dor-030238	Dipodomys ordii	70.18	5.00e-157	546.00
IUUC-Dse-031266	Dothistroma septosporum	41.85	2.00e-69	255.00
IUUC-Dme-032007	Drosophila melanogaster	52.29	2.00e-76	279.00
IUUC-Ete-032911	Echinops telfairi	55.12	2.00e-99	355.00
IUUC-Eca-033749	Equus caballus	77.42	2.00e-171	594.00
IUUC-Eeu-035170	Erinaceus europaeus	75.00	2.00e-169	588.00
IUUC-Fca-035498	Felis catus	76.03	8.00e-169	585.00
IUUC-Fal-037397	Ficedula albicollis	54.48	2.00e-116	412.00
IUUC-Fox-037747	Fusarium oxysporum	45.20	2.00e-67	248.00
IUUC-Fso-038429	Fusarium solani	45.10	4.00e-67	248.00
IUUC-Gmo-039378	Gadus morhua	50.76	4.00e-96	344.00
IUUC-Ggr-039939	Gaeumannomyces graminis	46.90	6.00e-72	264.00
IUUC-Gga-040187	Gallus gallus	58.51	1.00e-119	422.00
IUUC-Gac-042223	Gasterosteus aculeatus	51.28	1.00e-99	355.00
IUUC-Gma-042870	Glycine max	54.91	3.00e-75	274.00
IUUC-Ggo-045617	Gorilla gorilla	78.66	3.00e-180	624.00
IUUC-Hsa-046968	Homo sapiens	78.66	3.00e-180	624.00
IUUC-Hvu-047072	Hordeum vulgare	43.17	9.00e-57	213.00
IUUC-Kpa-049093	Komagataella pastoris	43.64	6.00e-49	187.00
IUUC-Lch-050346	Latimeria chalumnae	56.63	6.00e-115	406.00
IUUC-Lpe-051466	Leersia perrieri	53.66	1.00e-80	292.00
IUUC-Lma-053006	Leptosphaeria maculans	46.77	1.00e-64	239.00
IUUC-Laf-053422	Loxodonta africana	72.95	6.00e-166	576.00
IUUC-Mcc-055245	Macaca mulatta	77.22	6.00e-158	550.00
IUUC-Mor-056952	Magnaporthe oryzae	44.29	8.00e-68	250.00
IUUC-Mpo-057605	Magnaporthe poae	46.23	1.00e-72	266.00
IUUC-Mtr-057726	Medicago truncatula	55.85	7.00e-81	293.00
IUUC-Mla-059174	Melampsora laricipopulina	48.94	2.00e-73	269.00
IUUC-Mga-059562	Meleagris gallopavo	50.13	1.00e-86	313.00
IUUC-Mvi-060305	Microbotryum violaceum	48.11	2.00e-66	246.00
IUUC-Mmr-061588	Microcebus murinus	74.19	3.00e-171	593.00
IUUC-Mdo-061914	Monodelphis domestica	67.27	2.00e-142	498.00
IUUC-Mmu-063288	Mus musculus	74.19	3.00e-163	567.00
IUUC-Mac-064969	Musa acuminata	56.39	6.00e-81	293.00
IUUC-Mpu-066855	Mustela putorius furo	75.97	2.00e-170	590.00
IUUC-Mlu-068046	Myotis lucifugus	76.23	8.00e-169	586.00
IUUC-Nfi-068527	Neosartorya fischeri	45.26	2.00e-63	236.00
IUUC-Ncr-068678	Neurospora crassa	46.45	1.00e-69	256.00
IUUC-Nle-069848	Nomascus leucogenys	78.16	6.00e-179	619.00
IUUC-Opr-070589	Ochotona princeps	70.81	5.00e-148	516.00
IUUC-Ont-071733	Oreochromis niloticus	51.47	4.00e-90	324.00
IUUC-Oan-073399	Ornithorhynchus anatinus	72.95	4.00e-121	427.00
IUUC-Ocu-074063	Oryctolagus cuniculus	74.81	1.00e-172	598.00
IUUC-Oba-075264	Oryza barthii	55.47	2.00e-79	288.00
IUUC-Obr-076048	Oryza brachyantha	54.68	4.00e-79	287.00
IUUC-Ogl-077637	Oryza glaberrima	55.47	3.00e-79	288.00
IUUC-Ogu-078830	Oryza glumaepatula	55.47	2.00e-79	288.00
IUUC-Oin-079150	Oryza indica	55.47	1.00e-79	289.00
IUUC-Olo-080398	Oryza longistaminata	45.42	4.00e-58	217.00
IUUC-Ome-081544	Oryza meridionalis	43.54	4.00e-66	244.00
IUUC-Oni-082250	Oryza nivara	55.47	1.00e-79	289.00
IUUC-Opu-083638	Oryza punctata	54.29	7.00e-80	290.00
IUUC-Oru-084981	Oryza rufipogon	55.47	9.00e-80	289.00
IUUC-Osa-085961	Oryza sativa	55.47	9.00e-80	289.00
IUUC-Olu-087880	Ostreococcus lucimarinus	57.79	8.00e-85	306.00
IUUC-Oga-088891	Otolemur garnettii	74.61	3.00e-164	570.00
IUUC-Oar-090021	Ovis aries	75.68	9.00e-164	569.00
IUUC-Ptr-091458	Pan troglodytes	78.91	2.00e-180	624.00
IUUC-Pan-092546	Papio anubis	76.67	1.00e-158	552.00
IUUC-Psi-093280	Pelodiscus sinensis	62.67	5.00e-127	447.00
IUUC-Pma-094298	Petromyzon marinus	62.64	6.00e-91	326.00
IUUC-Pno-094847	Phaeosphaeria nodorum	47.35	4.00e-66	244.00
IUUC-Ppa-095855	Physcomitrella patens	52.82	2.00e-81	295.00
IUUC-Pfo-096428	Poecilia formosa	50.99	3.00e-97	348.00
IUUC-Pab-098696	Pongo abelii	78.47	4.00e-176	610.00
IUUC-Pop-099405	Populus trichocarpa	54.48	3.00e-81	294.00
IUUC-Pca-100740	Procavia capensis	68.98	2.00e-154	538.00
IUUC-Ppe-101854	Prunus persica	54.42	9.00e-82	296.00
IUUC-Pva-103212	Pteropus vampyrus	75.45	4.00e-168	583.00
IUUC-Pgr-103474	Puccinia graminis	48.14	1.00e-74	273.00
IUUC-Ptt-103933	Puccinia triticina	37.07	8.00e-39	154.00
IUUC-Pte-104089	Pyrenophora teres	39.01	2.00e-65	242.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	40.17	2.00e-65	242.00
IUUC-Rno-105057	Rattus norvegicus	75.19	7.00e-166	576.00
IUUC-Sha-107137	Sarcophilus harrisii	69.25	2.00e-146	511.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	47.43	2.00e-71	262.00
IUUC-Spo-108078	Schizosaccharomyces pombe	50.00	5.00e-74	270.00
IUUC-Smo-109288	Selaginella moellendorffii	55.26	5.00e-81	293.00
IUUC-Sit-110246	Setaria italica	52.82	1.00e-78	286.00
IUUC-Sly-111379	Solanum lycopersicum	54.77	8.00e-82	296.00
IUUC-Stu-112777	Solanum tuberosum	52.10	4.00e-81	294.00
IUUC-Sbi-114325	Sorghum bicolor	52.46	7.00e-79	286.00
IUUC-Sre-115203	Sporisorium reilianum	47.37	1.00e-56	213.00
IUUC-Ssc-115361	Sus scrofa	75.68	2.00e-171	594.00
IUUC-Tgu-116967	Taeniopygia guttata	60.53	5.00e-117	413.00
IUUC-Tru-117570	Takifugu rubripes	53.44	3.00e-102	364.00
IUUC-Tsy-119280	Tarsius syrichta	73.24	5.00e-84	304.00
IUUC-Tni-120721	Tetraodon nigroviridis	52.39	2.00e-102	365.00
IUUC-Tca-121494	Theobroma cacao	53.00	4.00e-81	294.00
IUUC-Tre-121869	Trichoderma reesei	44.34	2.00e-70	259.00
IUUC-Tvi-122510	Trichoderma virens	47.16	1.00e-68	253.00
IUUC-Tae-123071	Triticum aestivum	53.09	4.00e-78	284.00
IUUC-Tur-126240	Triticum urartu	53.09	1.00e-77	282.00
IUUC-Tme-126921	Tuber melanosporum	49.81	3.00e-70	258.00
IUUC-Tbe-127872	Tupaia belangeri	71.47	1.00e-151	529.00
IUUC-Ttr-129134	Tursiops truncatus	76.74	6.00e-164	569.00
IUUC-Uma-129412	Ustilago maydis	40.06	4.00e-56	211.00
IUUC-Vda-130003	Verticillium dahliae	44.76	2.00e-67	249.00
IUUC-Vvi-131272	Vitis vinifera	56.18	9.00e-82	296.00
IUUC-Xtr-132019	Xenopus tropicalis	54.57	2.00e-114	405.00
IUUC-Xma-134203	Xiphophorus maculatus	51.03	4.00e-101	361.00
IUUC-Yli-134503	Yarrowia lipolytica	43.63	3.00e-60	225.00
IUUC-Zma-135232	Zea mays	52.92	9.00e-79	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence