iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044580

UUCD1 version

UUC-GoG-01003

Ensembl Protein ID

ENSGGOP00000012762.2

UniProt Accession

G3RBC1; G3RBC1_GORGO

Protein Name

Uncharacterized protein

Gene Name

UBE2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000013085.2	ENSGGOT00000013129.2	ENSGGOP00000012762.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.50e-52	176.3	6	135

Active Site

Position(s)	Description	Evidence
81	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 6    lkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWsp 94
           +++l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g+Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G++Cl+il+  ++Wsp
   Q: 6    ISRLQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQ--NRWSP 91
           6789**************9.9************************************************************9..***** PP
   S: 95   alsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 92   TYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 135
           *****************************************996 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

KLPRWISRLQ EDPPVGVSGA PSENNIMQWN AVIFGPEGTP FEDGTFKLVI EFSEEYPNKP 60
PTVRFLSKMF HPNVYADGSI CLDILQNRWS PTYDVSSILT SIQSLLDEPN PNSPANSQAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATTACCGC GCTGGATTTC CAGGTTACAA GAGGACCCAC CTGTGGGTGT CAGTGGCGCA 60
CCATCTGAAA ACAACATCAT GCAGTGGAAT GCAGTTATAT TTGGGTGAGT TGAAAGGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005657--C:replication fork
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0060070--P:canonical Wnt signaling pathway
GO:0051026--P:chiasma assembly
GO:0033522--P:histone H2A ubiquitination
GO:0070076--P:histone lysine demethylation
GO:0001701--P:in utero embryonic development
GO:0006344--P:maintenance of chromatin silencing
GO:0045141--P:meiotic telomere clustering
GO:0043066--P:negative regulation of apoptotic process
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0033128--P:negative regulation of histone phosphorylation
GO:0010845--P:positive regulation of reciprocal meiotic recombination
GO:0006301--P:postreplication repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0050821--P:protein stabilization
GO:0042493--P:response to drug
GO:0009411--P:response to UV
GO:0007288--P:sperm axoneme assembly
GO:0070193--P:synaptonemal complex organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004063	Anas platyrhynchos	92.62	5.00e-76	275.00
IUUC-Dor-030452	Dipodomys ordii	100.00	6.00e-78	281.00
IUUC-Meu-056103	Macropus eugenii	100.00	6.00e-78	281.00
IUUC-Mga-059863	Meleagris gallopavo	100.00	1.00e-79	288.00
IUUC-Oan-072706	Ornithorhynchus anatinus	97.89	4.00e-79	286.00
IUUC-Ptt-103971	Puccinia triticina	72.88	3.00e-44	169.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence