iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115809

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU466375

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000011732.3	ENSSSCT00000033919.1	ENSSSCP00000029454.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.10e-09	36.6	10	60
E3 activity/RING/U-box	4.80e-06	26.8	6	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+ +     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLEDI----LQASGNFYiwrplriplkCPNCR 60
           **********.**************9777....455666655556666666****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           +e+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    DELTCPICYSIFEDPRVLPCSHTFCRNCLEDILQASGNfyiwrplriplKCPNCRSIIeiaptGIESLPVNFALRAIIEKYQQE 89
           7899*****************************999999**********99999986533321456777799999999999776 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MHNFEDELTC PICYSIFEDP RVLPCSHTFC RNCLEDILQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIAPTGI ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGGCACCT GAAGGCCCTC AGGGCGGAGG AGGGCGGGTA CGCTGCGCAG GTCTTAGCTT 60
CACACTGCAG GTTGTGGAGC TGTTTCAGCC GGTGGAGGTA CCTGGTTCGC TCGTCTCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0030992--C:intraciliary transport particle B
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0060271--P:cilium assembly
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

ssc:100152755

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	90.80	0.00e+00	755.00
IUUC-Apl-003996	Anas platyrhynchos	54.57	1.00e-121	429.00
IUUC-Aca-005141	Anolis carolinensis	57.28	3.00e-131	461.00
IUUC-Ame-011353	Astyanax mexicanus	51.13	7.00e-98	350.00
IUUC-Bta-013440	Bos taurus	90.86	0.00e+00	681.00
IUUC-Cja-019076	Callithrix jacchus	87.12	3.00e-175	608.00
IUUC-Cfa-021168	Canis familiaris	91.02	0.00e+00	756.00
IUUC-Cpo-021702	Cavia porcellus	76.62	2.00e-180	624.00
IUUC-Csa-024141	Chlorocebus sabaeus	88.83	0.00e+00	678.00
IUUC-Dre-028408	Danio rerio	46.47	8.00e-88	317.00
IUUC-Dno-029180	Dasypus novemcinctus	87.59	0.00e+00	729.00
IUUC-Ete-033028	Echinops telfairi	85.02	6.00e-169	587.00
IUUC-Eca-034357	Equus caballus	90.07	0.00e+00	721.00
IUUC-Eeu-034909	Erinaceus europaeus	81.27	7.00e-156	544.00
IUUC-Fca-036287	Felis catus	91.32	0.00e+00	759.00
IUUC-Gmo-038657	Gadus morhua	42.77	8.00e-64	238.00
IUUC-Gga-040739	Gallus gallus	55.67	1.00e-132	465.00
IUUC-Gac-041586	Gasterosteus aculeatus	46.06	4.00e-91	329.00
IUUC-Ggo-045307	Gorilla gorilla	86.10	0.00e+00	700.00
IUUC-Hsa-045690	Homo sapiens	86.85	0.00e+00	702.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	90.57	0.00e+00	763.00
IUUC-Loc-052774	Lepisosteus oculatus	51.42	2.00e-100	360.00
IUUC-Laf-054522	Loxodonta africana	87.06	0.00e+00	721.00
IUUC-Mcc-055145	Macaca mulatta	88.59	0.00e+00	714.00
IUUC-Meu-056214	Macropus eugenii	45.40	4.00e-58	218.00
IUUC-Mmr-061197	Microcebus murinus	92.31	0.00e+00	773.00
IUUC-Mdo-062631	Monodelphis domestica	59.75	3.00e-133	468.00
IUUC-Mmu-064217	Mus musculus	83.83	0.00e+00	677.00
IUUC-Mpu-065691	Mustela putorius furo	92.56	0.00e+00	772.00
IUUC-Mlu-067742	Myotis lucifugus	88.28	0.00e+00	706.00
IUUC-Nle-069722	Nomascus leucogenys	86.60	0.00e+00	731.00
IUUC-Oan-073382	Ornithorhynchus anatinus	58.60	1.00e-132	465.00
IUUC-Ocu-073896	Oryctolagus cuniculus	87.42	2.00e-170	592.00
IUUC-Ola-086767	Oryzias latipes	43.60	1.00e-78	288.00
IUUC-Oar-089206	Ovis aries	89.08	0.00e+00	749.00
IUUC-Pan-092189	Papio anubis	88.83	0.00e+00	716.00
IUUC-Psi-093523	Pelodiscus sinensis	61.33	2.00e-141	495.00
IUUC-Pma-094162	Petromyzon marinus	35.53	5.00e-46	177.00
IUUC-Pfo-096032	Poecilia formosa	45.02	2.00e-86	312.00
IUUC-Pva-103089	Pteropus vampyrus	89.53	0.00e+00	720.00
IUUC-Pgr-103338	Puccinia graminis	40.32	5.00e-07	47.40
IUUC-Ptt-103920	Puccinia triticina	41.94	7.00e-06	43.90
IUUC-Rno-105440	Rattus norvegicus	85.82	0.00e+00	692.00
IUUC-Sar-113301	Sorex araneus	88.12	5.00e-51	195.00
IUUC-Tru-118402	Takifugu rubripes	44.07	8.00e-92	330.00
IUUC-Tni-119737	Tetraodon nigroviridis	44.05	7.00e-83	300.00
IUUC-Tbe-127434	Tupaia belangeri	86.11	4.00e-164	571.00
IUUC-Ttr-128921	Tursiops truncatus	89.53	0.00e+00	723.00
IUUC-Vpa-130397	Vicugna pacos	92.04	0.00e+00	763.00
IUUC-Xtr-132752	Xenopus tropicalis	41.73	3.00e-83	301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence