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Tag Content
iUUCD ID IUUC-Vvi-131174
Ensembl Protein ID VIT_15s0048g01110.t01
UniProt Accession D7U7Q9; D7U7Q9_VITVI
Genbank Protein ID CBI38838.3
Protein Name Ubiquitin-related modifier 1 homolog
Genbank Nucleotide ID FN596739
Gene Name VIT_15s0048g01110
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
VIT_15s0048g01110 VIT_15s0048g01110.t01 VIT_15s0048g01110.t01
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 39.76 4.00e-14 70.50 IUUC-Sce-106366
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Vitis vinifera
Functional Description
(View)

Functional Description



     Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Protein Sequence
(Fasta)
MQLTLEFGGG LELLCESVKI HSVNVDPQVG EEKLTMKDLL SWVRANLIKE RPEMFMKGDS 60
VRPGVLVLVN DCDWELSGQL DTTLEEKDVI VFISTLHGG 99
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Protein Fasta Sequence



>IUUC-Vvi-131174|ULD,UBQ_Other|Vitis vinifera
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Nucleotide Sequence
(Fasta)
GGGCTTTGGT TGGACCGAAA AGAAAAGCCC ATCTCTGTTT CTGCTTTTGC TTTCTACCTA 60
GGGTTTAGAA ATTTTCTCTC GTCTTCGGTT CGGAATTTTC TTTTTGGGGA TGCAACTGAC 120
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Nucleotide Fasta Sequence



>IUUC-Vvi-131174|ULD,UBQ_Other|Vitis vinifera
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1185--Reference proteome
KW-0819--tRNA processing
KW-0833--Ubl conjugation pathway

Interpro

IPR012675--Beta-grasp_dom
IPR016155--Mopterin_synth/thiamin_S_b
IPR015221--Urm1

Pfam

PF09138--Urm1

Gene Ontology

GO:0005829--C:cytosol
GO:0032447--P:protein urmylation
GO:0034227--P:tRNA thio-modification
GO:0002098--P:tRNA wobble uridine modification

KEGG vvi:100257432
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002254 Ailuropoda melanoleuca 55.56 4.00e-29 118.00
IUUC-Atr-003089 Amborella trichopoda 72.73 2.00e-39 152.00
IUUC-Apl-003382 Anas platyrhynchos 55.91 2.00e-27 112.00
IUUC-Aca-004981 Anolis carolinensis 56.70 1.00e-28 116.00
IUUC-Aly-005517 Arabidopsis lyrata 82.61 2.00e-40 155.00
IUUC-Ath-006718 Arabidopsis thaliana 84.85 1.00e-38 149.00
IUUC-Ago-007917 Ashbya gossypii 37.62 2.00e-18 83.20
IUUC-Acl-008054 Aspergillus clavatus 56.00 7.00e-13 63.90
IUUC-Afl-008704 Aspergillus flavus 43.82 6.00e-16 73.90
IUUC-Aor-009890 Aspergillus oryzae 45.54 4.00e-20 89.00
IUUC-Bta-012448 Bos taurus 56.57 4.00e-29 118.00
IUUC-Bci-013865 Botrytis cinerea 39.22 3.00e-16 75.90
IUUC-Bdi-014980 Brachypodium distachyon 71.26 5.00e-31 124.00
IUUC-Bol-016055 Brassica oleracea 82.35 3.00e-37 145.00
IUUC-Bra-016845 Brassica rapa 82.35 3.00e-37 145.00
IUUC-Cel-018485 Caenorhabditis elegans 36.89 2.00e-12 62.40
IUUC-Cja-019587 Callithrix jacchus 55.56 4.00e-29 118.00
IUUC-Cfa-020653 Canis familiaris 57.58 3.00e-29 119.00
IUUC-Cpo-021622 Cavia porcellus 55.56 4.00e-29 118.00
IUUC-Cre-023015 Chlamydomonas reinhardtii 54.55 1.00e-28 116.00
IUUC-Csa-023756 Chlorocebus sabaeus 53.95 1.00e-20 90.90
IUUC-Cgl-026518 Colletotrichum gloeosporioides 38.24 3.00e-15 72.40
IUUC-Cne-026953 Cryptococcus neoformans 50.49 1.00e-24 104.00
IUUC-Cme-027314 Cyanidioschyzon merolae 50.00 3.00e-21 91.70
IUUC-Dre-027884 Danio rerio 60.82 7.00e-31 124.00
IUUC-Dno-029262 Dasypus novemcinctus 53.16 6.00e-20 89.40
IUUC-Dor-030601 Dipodomys ordii 54.69 1.00e-15 73.60
IUUC-Dme-031893 Drosophila melanogaster 51.52 3.00e-27 112.00
IUUC-Ete-032773 Echinops telfairi 53.61 3.00e-27 112.00
IUUC-Eca-034187 Equus caballus 56.57 2.00e-29 119.00
IUUC-Eeu-034808 Erinaceus europaeus 54.55 2.00e-28 115.00
IUUC-Fca-036107 Felis catus 56.57 3.00e-29 118.00
IUUC-Fal-036607 Ficedula albicollis 54.84 2.00e-26 108.00
IUUC-Fox-037698 Fusarium oxysporum 34.31 3.00e-14 69.30
IUUC-Gmo-039492 Gadus morhua 60.82 3.00e-29 119.00
IUUC-Ggr-039965 Gaeumannomyces graminis 37.62 2.00e-13 67.00
IUUC-Gga-041268 Gallus gallus 56.70 3.00e-29 118.00
IUUC-Gac-042111 Gasterosteus aculeatus 56.57 6.00e-29 117.00
IUUC-Gma-043240 Glycine max 80.00 1.00e-37 146.00
IUUC-Ggo-045176 Gorilla gorilla 53.95 1.00e-14 70.90
IUUC-Hsa-046077 Homo sapiens 54.55 5.00e-23 98.20
IUUC-Itr-048111 Ictidomys tridecemlineatus 57.14 3.00e-21 91.70
IUUC-Kpa-049157 Komagataella pastoris 39.60 1.00e-16 77.00
IUUC-Lch-049889 Latimeria chalumnae 53.54 3.00e-27 112.00
IUUC-Lpe-050783 Leersia perrieri 74.70 3.00e-33 132.00
IUUC-Loc-052400 Lepisosteus oculatus 57.58 8.00e-30 120.00
IUUC-Lma-053259 Leptosphaeria maculans 39.60 2.00e-14 69.70
IUUC-Laf-053596 Loxodonta africana 54.46 8.00e-28 114.00
IUUC-Mcc-054845 Macaca mulatta 55.56 3.00e-26 108.00
IUUC-Meu-055968 Macropus eugenii 57.58 4.00e-30 121.00
IUUC-Mor-057126 Magnaporthe oryzae 34.31 7.00e-12 61.60
IUUC-Mpo-057311 Magnaporthe poae 34.95 2.00e-13 67.00
IUUC-Mtr-058266 Medicago truncatula 82.76 4.00e-37 144.00
IUUC-Mla-058847 Melampsora laricipopulina 33.33 2.00e-07 47.00
IUUC-Mga-059468 Meleagris gallopavo 55.91 2.00e-27 112.00
IUUC-Mvi-060235 Microbotryum violaceum 32.43 4.00e-16 76.30
IUUC-Mdo-061948 Monodelphis domestica 56.57 8.00e-30 120.00
IUUC-Mmu-063946 Mus musculus 57.73 6.00e-29 117.00
IUUC-Mac-064812 Musa acuminata 80.00 5.00e-37 144.00
IUUC-Mpu-066763 Mustela putorius furo 57.58 5.00e-30 121.00
IUUC-Mlu-066970 Myotis lucifugus 55.26 8.00e-21 90.50
IUUC-Ncr-068824 Neurospora crassa 39.60 2.00e-16 76.30
IUUC-Nle-069849 Nomascus leucogenys 53.95 2.00e-20 90.50
IUUC-Opr-070227 Ochotona princeps 55.56 4.00e-29 118.00
IUUC-Ont-072530 Oreochromis niloticus 58.59 1.00e-29 120.00
IUUC-Oan-073191 Ornithorhynchus anatinus 57.14 4.00e-26 108.00
IUUC-Ocu-074460 Oryctolagus cuniculus 57.58 3.00e-29 118.00
IUUC-Oba-075499 Oryza barthii 71.43 2.00e-32 130.00
IUUC-Obr-076896 Oryza brachyantha 72.62 2.00e-32 131.00
IUUC-Ogl-077834 Oryza glaberrima 71.43 1.00e-32 130.00
IUUC-Ogu-078622 Oryza glumaepatula 71.43 1.00e-32 130.00
IUUC-Oin-079358 Oryza indica 71.43 2.00e-32 130.00
IUUC-Olo-081035 Oryza longistaminata 71.88 3.00e-35 140.00
IUUC-Oni-082425 Oryza nivara 71.43 1.00e-32 130.00
IUUC-Opu-083461 Oryza punctata 72.29 4.00e-32 129.00
IUUC-Oru-084875 Oryza rufipogon 74.65 4.00e-26 107.00
IUUC-Oga-089128 Otolemur garnettii 56.57 1.00e-29 119.00
IUUC-Oar-089896 Ovis aries 56.57 4.00e-29 118.00
IUUC-Ptr-091618 Pan troglodytes 53.95 1.00e-14 71.20
IUUC-Pan-092238 Papio anubis 53.95 1.00e-20 90.90
IUUC-Psi-093879 Pelodiscus sinensis 55.56 4.00e-29 118.00
IUUC-Pma-094484 Petromyzon marinus 56.79 2.00e-23 99.00
IUUC-Ppa-095801 Physcomitrella patens 65.66 1.00e-25 107.00
IUUC-Pfo-097192 Poecilia formosa 61.05 7.00e-29 117.00
IUUC-Pab-098203 Pongo abelii 54.55 5.00e-23 98.20
IUUC-Pop-099614 Populus trichocarpa 83.53 8.00e-38 147.00
IUUC-Pca-100507 Procavia capensis 56.58 6.00e-21 90.90
IUUC-Ppe-101174 Prunus persica 86.87 1.00e-47 179.00
IUUC-Pva-102735 Pteropus vampyrus 54.55 3.00e-26 108.00
IUUC-Pgr-103510 Puccinia graminis 35.19 2.00e-08 49.70
IUUC-Ptt-103918 Puccinia triticina 35.24 2.00e-09 53.50
IUUC-Pte-104173 Pyrenophora teres 40.20 2.00e-16 76.30
IUUC-Pyt-104806 Pyrenophora triticirepentis 40.20 2.00e-16 76.60
IUUC-Rno-105820 Rattus norvegicus 58.95 4.00e-29 118.00
IUUC-Sce-106366 Saccharomyces cerevisiae 37.62 2.00e-17 79.30
IUUC-Sja-107727 Schizosaccharomyces japonicus 40.82 2.00e-13 66.20
IUUC-Spo-108074 Schizosaccharomyces pombe 40.78 9.00e-10 53.90
IUUC-Smo-108944 Selaginella moellendorffii 60.44 1.00e-26 109.00
IUUC-Sit-110277 Setaria italica 75.90 1.00e-32 129.00
IUUC-Sly-111505 Solanum lycopersicum 82.35 2.00e-38 149.00
IUUC-Stu-112076 Solanum tuberosum 83.53 8.00e-39 150.00
IUUC-Sbi-114274 Sorghum bicolor 67.02 2.00e-31 125.00
IUUC-Sre-114953 Sporisorium reilianum 46.08 2.00e-20 89.70
IUUC-Ssc-115418 Sus scrofa 55.56 7.00e-29 117.00
IUUC-Tgu-117311 Taeniopygia guttata 53.76 5.00e-26 107.00
IUUC-Tru-118598 Takifugu rubripes 57.14 1.00e-25 106.00
IUUC-Tni-120109 Tetraodon nigroviridis 57.29 1.00e-25 106.00
IUUC-Tca-120942 Theobroma cacao 81.93 1.00e-36 143.00
IUUC-Tre-122099 Trichoderma reesei 40.86 4.00e-11 58.50
IUUC-Tvi-122285 Trichoderma virens 40.59 1.00e-13 67.00
IUUC-Tae-125193 Triticum aestivum 72.62 3.00e-33 131.00
IUUC-Tur-126677 Triticum urartu 64.58 8.00e-31 124.00
IUUC-Tme-127120 Tuber melanosporum 40.20 7.00e-17 78.20
IUUC-Tbe-128050 Tupaia belangeri 40.40 4.00e-15 71.60
IUUC-Ttr-129019 Tursiops truncatus 54.55 6.00e-29 117.00
IUUC-Uma-129483 Ustilago maydis 47.12 1.00e-20 90.50
IUUC-Vda-129690 Verticillium dahliae 32.74 8.00e-10 54.70
IUUC-Xma-133862 Xiphophorus maculatus 61.05 7.00e-29 117.00
IUUC-Yli-134398 Yarrowia lipolytica 42.00 5.00e-17 77.80
IUUC-Zma-134964 Zea mays 73.81 2.00e-31 125.00
Created Date 25-Jun-2017

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