iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007475

UUCD1 version

UUC-ArT-01001

Ensembl Protein ID

AT4G03190.1

UniProt Accession

Q9ZR12; Q94AU0; Q9C5Y7; GRH1_ARATH

Genbank Protein ID

AAK01147.1; AAD14447.1; CAB77804.1; AEE82287.1; AAK76473.1; AAN12969.1

Protein Name

GRR1-like protein 1; Protein AUXIN SIGNALING F-BOX 1

Genbank Nucleotide ID

AF291816; AC005275; AL161496; CP002687; AY045799; AY150427

Gene Name

GRH1; AFB1; FBL18; GER1; LRF1; At4g03190; F4C21.11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G03190	AT4G03190.1	AT4G03190.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	15992545

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.24	12.3	3	38

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 104  drlpeeilveilklldkee.llraarvcrrwqelas 138
            r+p ++l +il+++d++e   ++++vc++w e+ +
   Q: 3    LRFPPKVLEHILSFIDSNEdRNSVSLVCKSWFETER 38
           6899***********66555***********99877 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. Involved in embryogenesis regulation by auxin. Confers sensitivity to the virulent bacterial pathogen P.syringae. Mediates glucose repression in yeast.

Protein Sequence
(Fasta)

MGLRFPPKVL EHILSFIDSN EDRNSVSLVC KSWFETERKT RKRVFVGNCY AVSPAAVTRR 60
FPEMRSLTLK GKPHFADYNL VPDGWGGYAW PWIEAMAAKS SSLEEIRMKR MVVTDECLEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGAACTGG GTAATACCAT AAATGATTAG ATCCACGAGT TCTCACACAG ACTTACATGT 60
GATGGATCAC AGAGTAAACT AATTATGATT AAGGAAACTA ATTATATTAG TGAGCTATAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0927--Auxin signaling pathway
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0539--Nucleus
KW-0611--Plant defense
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0010011--F:auxin binding
GO:0000822--F:inositol hexakisphosphate binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0009734--P:auxin-activated signaling pathway
GO:0006952--P:defense response
GO:0045014--P:negative regulation of transcription by glucose
GO:0010152--P:pollen maturation
GO:0009733--P:response to auxin

KEGG

ath:AT4G03190

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005750	Arabidopsis lyrata	96.41	0.00e+00	1153.00
IUUC-Bol-016366	Brassica oleracea	84.10	0.00e+00	1005.00
IUUC-Bra-016668	Brassica rapa	84.64	0.00e+00	1016.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence