iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061911

UUCD1 version

UUC-MoD-00737

Ensembl Protein ID

ENSMODP00000001321.2

UniProt Accession

F7DPG2; F7DPG2_MONDO

Protein Name

Uncharacterized protein

Gene Name

UHRF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001108.2	ENSMODT00000001349.2	ENSMODP00000001321.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.60e-09	35.8	323	371
ULD/UDP/UBQ/UBQ_PIM	2.60e-14	53.1	1	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
            C+vCg +++ +k  ++C++C+ +fH  Cl+++  +  p++e+w+Cp+Cr+
   Q: 323  ACHVCGGKQDPDK-QLMCDECDMAFHIYCLSPP-LSRIPDDEDWYCPECRN 371
           59*****999997.566****************.***************85 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgke.fel.evseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           m+++v+t++gke  ++ ++s+ ++veel+ ki++++ v+p +q+L y Gk+++D  +L ++++  +++v l+v++s+
   Q: 1    MWIQVRTMDGKEtHRVdSLSKLTKVEELRLKIQEVFRVEPGRQRLFYRGKQMEDGHSLFDYNVGLNDIVQLLVRQSP 77
           89**********7667789999****************************************************987 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MWIQVRTMDG KETHRVDSLS KLTKVEELRL KIQEVFRVEP GRQRLFYRGK QMEDGHSLFD 60
YNVGLNDIVQ LLVRQSPAVL SVPSKEKDSE LSDTDSGCCS GQSESDKSSN HGEGALEIDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTACCAAG ATGTGGATCC AGGTTCGTAC CATGGATGGC AAGGAGACCC ACAGGGTAGA 60
CTCCCTCTCT AAACTCACCA AAGTGGAGGA GCTGAGATTG AAAATCCAGG AAGTGTTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015947--PUA-like_domain
IPR014722--Rib_L2_dom2
IPR003105--SRA_YDG
IPR021991--TTD_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS51015--YDG
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00628--PHD
PF02182--SAD_SRA
PF12148--TTD
PF00240--ubiquitin

SMART

SM00249--PHD
SM00184--RING
SM00466--SRA
SM00213--UBQ

Gene Ontology

GO:0005720--C:nuclear heterochromatin
GO:0016363--C:nuclear matrix
GO:0005657--C:replication fork
GO:0044729--F:hemi-methylated DNA-binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0010390--P:histone monoubiquitination
GO:0010216--P:maintenance of DNA methylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0051865--P:protein autoubiquitination
GO:0090308--P:regulation of methylation-dependent chromatin silencing

KEGG

mdo:100018911

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001285	Ailuropoda melanoleuca	81.55	0.00e+00	1019.00
IUUC-Apl-003819	Anas platyrhynchos	83.67	0.00e+00	1259.00
IUUC-Aca-004970	Anolis carolinensis	66.01	0.00e+00	1030.00
IUUC-Aly-006276	Arabidopsis lyrata	35.66	4.00e-51	196.00
IUUC-Ame-011845	Astyanax mexicanus	74.49	0.00e+00	1105.00
IUUC-Bta-012600	Bos taurus	74.06	0.00e+00	1140.00
IUUC-Bci-013703	Botrytis cinerea	31.03	3.00e-11	63.50
IUUC-Bol-015235	Brassica oleracea	33.10	8.00e-48	185.00
IUUC-Bra-017592	Brassica rapa	34.95	6.00e-46	179.00
IUUC-Cja-018864	Callithrix jacchus	76.82	0.00e+00	1186.00
IUUC-Cfa-020558	Canis familiaris	81.88	0.00e+00	1019.00
IUUC-Cpo-022125	Cavia porcellus	73.64	0.00e+00	1161.00
IUUC-Cre-022645	Chlamydomonas reinhardtii	30.13	9.00e-22	98.60
IUUC-Csa-023649	Chlorocebus sabaeus	74.19	0.00e+00	1145.00
IUUC-Cin-025454	Ciona intestinalis	53.41	0.00e+00	764.00
IUUC-Cgl-026498	Colletotrichum gloeosporioides	32.64	9.00e-12	65.10
IUUC-Cne-026942	Cryptococcus neoformans	46.67	2.00e-29	121.00
IUUC-Dre-028200	Danio rerio	73.04	0.00e+00	1149.00
IUUC-Dno-029523	Dasypus novemcinctus	78.92	0.00e+00	923.00
IUUC-Dor-031084	Dipodomys ordii	73.68	0.00e+00	1147.00
IUUC-Eca-033266	Equus caballus	76.65	0.00e+00	1148.00
IUUC-Eeu-035077	Erinaceus europaeus	81.27	9.00e-142	496.00
IUUC-Fca-035685	Felis catus	69.98	0.00e+00	1051.00
IUUC-Fal-037550	Ficedula albicollis	81.49	0.00e+00	1162.00
IUUC-Gmo-039452	Gadus morhua	70.82	0.00e+00	1108.00
IUUC-Gga-040484	Gallus gallus	83.40	0.00e+00	1333.00
IUUC-Gac-042196	Gasterosteus aculeatus	71.14	0.00e+00	1117.00
IUUC-Ggo-045414	Gorilla gorilla	77.72	0.00e+00	1206.00
IUUC-Hsa-046236	Homo sapiens	77.72	0.00e+00	1206.00
IUUC-Itr-047867	Ictidomys tridecemlineatus	73.47	0.00e+00	1142.00
IUUC-Lch-050162	Latimeria chalumnae	72.14	0.00e+00	1117.00
IUUC-Loc-051806	Lepisosteus oculatus	76.05	0.00e+00	1183.00
IUUC-Lma-052953	Leptosphaeria maculans	25.35	9.00e-11	61.60
IUUC-Laf-053671	Loxodonta africana	76.37	0.00e+00	1200.00
IUUC-Mcc-055513	Macaca mulatta	77.15	0.00e+00	1201.00
IUUC-Mpo-057318	Magnaporthe poae	30.39	2.00e-09	57.00
IUUC-Mla-058836	Melampsora laricipopulina	42.16	1.00e-33	137.00
IUUC-Mga-059759	Meleagris gallopavo	83.00	0.00e+00	1217.00
IUUC-Mvi-060378	Microbotryum violaceum	47.28	2.00e-33	136.00
IUUC-Mmr-060600	Microcebus murinus	67.25	0.00e+00	994.00
IUUC-Mmu-063738	Mus musculus	68.13	0.00e+00	1052.00
IUUC-Mpu-065696	Mustela putorius furo	77.39	0.00e+00	1186.00
IUUC-Mlu-067538	Myotis lucifugus	70.74	0.00e+00	1097.00
IUUC-Opr-070813	Ochotona princeps	61.00	4.00e-154	538.00
IUUC-Ont-072292	Oreochromis niloticus	72.41	0.00e+00	1131.00
IUUC-Oni-082510	Oryza nivara	33.17	4.00e-45	176.00
IUUC-Oru-084985	Oryza rufipogon	33.17	3.00e-45	177.00
IUUC-Ola-086416	Oryzias latipes	70.34	0.00e+00	1118.00
IUUC-Oga-088221	Otolemur garnettii	75.84	0.00e+00	1186.00
IUUC-Oar-089604	Ovis aries	70.03	0.00e+00	1045.00
IUUC-Ptr-090559	Pan troglodytes	77.69	0.00e+00	1204.00
IUUC-Pan-092855	Papio anubis	77.15	0.00e+00	1203.00
IUUC-Psi-093763	Pelodiscus sinensis	86.90	0.00e+00	986.00
IUUC-Pma-094339	Petromyzon marinus	66.75	0.00e+00	979.00
IUUC-Ppa-095940	Physcomitrella patens	34.91	1.00e-49	191.00
IUUC-Pfo-096243	Poecilia formosa	69.70	0.00e+00	1107.00
IUUC-Pab-098243	Pongo abelii	77.35	0.00e+00	1185.00
IUUC-Pca-100503	Procavia capensis	72.94	0.00e+00	1118.00
IUUC-Pva-102240	Pteropus vampyrus	76.36	0.00e+00	962.00
IUUC-Pgr-103644	Puccinia graminis	49.06	3.00e-33	136.00
IUUC-Ptt-103867	Puccinia triticina	45.00	2.00e-33	137.00
IUUC-Rno-105345	Rattus norvegicus	68.35	0.00e+00	1050.00
IUUC-Sha-106618	Sarcophilus harrisii	95.35	0.00e+00	1458.00
IUUC-Sly-111415	Solanum lycopersicum	46.19	3.00e-45	176.00
IUUC-Sar-113651	Sorex araneus	72.18	7.00e-88	317.00
IUUC-Sbi-114726	Sorghum bicolor	47.42	2.00e-41	164.00
IUUC-Sre-115182	Sporisorium reilianum	43.62	4.00e-34	139.00
IUUC-Ssc-116081	Sus scrofa	74.66	0.00e+00	1159.00
IUUC-Tgu-116538	Taeniopygia guttata	84.50	0.00e+00	1071.00
IUUC-Tru-117599	Takifugu rubripes	69.88	0.00e+00	1092.00
IUUC-Tca-121614	Theobroma cacao	46.49	2.00e-46	180.00
IUUC-Tme-127149	Tuber melanosporum	48.55	1.00e-27	117.00
IUUC-Ttr-128522	Tursiops truncatus	74.43	0.00e+00	1154.00
IUUC-Vda-129727	Verticillium dahliae	27.78	1.00e-07	50.40
IUUC-Xtr-132432	Xenopus tropicalis	73.43	0.00e+00	1149.00
IUUC-Xma-133516	Xiphophorus maculatus	70.50	0.00e+00	1125.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence