iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091584

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03102669

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000008421.5	ENSPTRT00000015524.5	ENSPTRP00000014368.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.90e-60	203.2	416	772

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 416  GLINKGNWCYINATLQALVACPPMYHLMKF-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 502
           9***************************99.333333.334799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsdeaeekkkkknk... 139
            +++ l   ++++s + +q+Da+E+l f+l++l+ee+ +                  kn++++eee+e++ e s++++e+   +nk   
   Q: 503  YIYRLLTVNKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkkllspssekltisngPKNHSVNEEEQEEQGEGSEDEWEQVGPRNKtsv 591
           ******99999866599********************5566799999999999999888888888888888888887777777777777 PP
   S: 140  ........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekk 220
                   ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k k+++e +++
   Q: 592  trqadfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKTKQEVEISRR 672
           77787888***********9.688999999*******************99...****************8....99999********* PP
   S: 221  lklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.Wl 307
           ++l+klP+vL+lhLkRf ++++++++ k+ k++e+p  L++s    +               vv+H+G s+ +GHY+++v +   + Wl
   Q: 673  VTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYPVDLEIS----K---------------VVYHHGnSATGGHYTTDVFQIGLNgWL 741
           *******************9998886.*********888877....4...............999*****************87777** PP
   S: 308  lfdDskVtevkeeevleetg.staYvlfYkr 337
           ++dD++V+++++ +v++ t+ +taY+l+Y+r
   Q: 742  RIDDQTVKVINQYQVVKPTAeRTAYLLYYRR 772
           *****************9889********98 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MALHSPQYIF GDFSPDEFNQ FFVTPRSSVE LPPYSGTVLC GTQAVDKLPD GQEYQRIEFG 60
VGEVIEPSDT SPRTPSYSIS STLNPQAPEF ILGCTASKIT PDGITKEASY GSIDCQYPGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCTCC ACAGCCCGCA GGTAGCCGCC GGTATGCGCC TTCGGCCGGA AGGGGCCCGA 60
GCCCGGGGCG GGCGGACGCC GCGGCGGGCG GGCGTCCGCG CCCTGCCCGG AGCGAGCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	29.58	3.00e-41	163.00
IUUC-Aml-001584	Ailuropoda melanoleuca	85.48	0.00e+00	1267.00
IUUC-Atr-002927	Amborella trichopoda	33.94	6.00e-54	205.00
IUUC-Apl-003988	Anas platyrhynchos	76.35	0.00e+00	1098.00
IUUC-Aca-004461	Anolis carolinensis	84.13	2.00e-150	524.00
IUUC-Aly-006038	Arabidopsis lyrata	35.06	4.00e-52	199.00
IUUC-Ath-007328	Arabidopsis thaliana	34.81	6.00e-51	195.00
IUUC-Ago-007717	Ashbya gossypii	27.93	3.00e-38	153.00
IUUC-Acl-008188	Aspergillus clavatus	31.85	4.00e-57	216.00
IUUC-Afl-008456	Aspergillus flavus	35.76	8.00e-42	164.00
IUUC-Afu-009067	Aspergillus fumigatus	34.44	3.00e-59	223.00
IUUC-Ani-009483	Aspergillus nidulans	32.10	3.00e-57	216.00
IUUC-Ang-009639	Aspergillus niger	33.08	2.00e-54	207.00
IUUC-Aor-010040	Aspergillus oryzae	34.15	5.00e-54	206.00
IUUC-Ate-010310	Aspergillus terreus	32.08	1.00e-55	211.00
IUUC-Ame-011012	Astyanax mexicanus	74.29	4.00e-153	535.00
IUUC-Bgr-012311	Blumeria graminis	29.59	4.00e-41	163.00
IUUC-Bta-013299	Bos taurus	83.75	0.00e+00	1201.00
IUUC-Bci-013783	Botrytis cinerea	35.57	5.00e-54	206.00
IUUC-Bdi-015039	Brachypodium distachyon	30.83	8.00e-46	178.00
IUUC-Bol-015806	Brassica oleracea	35.75	1.00e-59	223.00
IUUC-Bra-017076	Brassica rapa	35.75	7.00e-60	224.00
IUUC-Cja-018715	Callithrix jacchus	92.68	0.00e+00	1412.00
IUUC-Cfa-020194	Canis familiaris	86.36	0.00e+00	1283.00
IUUC-Cpo-022272	Cavia porcellus	73.92	0.00e+00	1021.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	33.45	4.00e-29	122.00
IUUC-Csa-023310	Chlorocebus sabaeus	94.70	0.00e+00	1436.00
IUUC-Cho-024966	Choloepus hoffmanni	78.25	0.00e+00	953.00
IUUC-Cin-025616	Ciona intestinalis	44.84	8.00e-97	347.00
IUUC-Csv-026043	Ciona savignyi	44.08	2.00e-92	332.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	32.00	2.00e-41	164.00
IUUC-Cne-026962	Cryptococcus neoformans	33.61	1.00e-44	175.00
IUUC-Cme-027113	Cyanidioschyzon merolae	28.18	3.00e-30	126.00
IUUC-Dre-028072	Danio rerio	75.27	0.00e+00	674.00
IUUC-Dno-029489	Dasypus novemcinctus	85.50	0.00e+00	1299.00
IUUC-Dor-031068	Dipodomys ordii	74.19	1.00e-138	486.00
IUUC-Dse-031553	Dothistroma septosporum	34.88	2.00e-50	194.00
IUUC-Dme-031759	Drosophila melanogaster	39.18	3.00e-76	281.00
IUUC-Ete-032549	Echinops telfairi	77.93	0.00e+00	883.00
IUUC-Eca-033380	Equus caballus	84.49	0.00e+00	1286.00
IUUC-Eeu-034818	Erinaceus europaeus	80.98	0.00e+00	1189.00
IUUC-Fca-035535	Felis catus	84.36	0.00e+00	1138.00
IUUC-Fal-036627	Ficedula albicollis	73.80	0.00e+00	1050.00
IUUC-Fox-037904	Fusarium oxysporum	34.64	2.00e-48	187.00
IUUC-Fso-038170	Fusarium solani	32.88	1.00e-48	188.00
IUUC-Gmo-039499	Gadus morhua	68.12	0.00e+00	631.00
IUUC-Ggr-040042	Gaeumannomyces graminis	34.13	1.00e-55	211.00
IUUC-Gga-040571	Gallus gallus	75.88	0.00e+00	1091.00
IUUC-Gac-041345	Gasterosteus aculeatus	73.49	7.00e-180	624.00
IUUC-Gma-043436	Glycine max	33.59	1.00e-54	207.00
IUUC-Ggo-044652	Gorilla gorilla	96.62	0.00e+00	1504.00
IUUC-Hsa-045864	Homo sapiens	96.62	0.00e+00	1506.00
IUUC-Hvu-047071	Hordeum vulgare	31.47	2.00e-48	186.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	86.11	0.00e+00	951.00
IUUC-Kpa-049132	Komagataella pastoris	29.28	6.00e-42	165.00
IUUC-Lch-050040	Latimeria chalumnae	67.02	0.00e+00	876.00
IUUC-Loc-052449	Lepisosteus oculatus	71.73	0.00e+00	669.00
IUUC-Lma-053248	Leptosphaeria maculans	34.31	5.00e-53	202.00
IUUC-Laf-054121	Loxodonta africana	85.12	0.00e+00	1259.00
IUUC-Mcc-055514	Macaca mulatta	94.95	0.00e+00	1439.00
IUUC-Meu-056873	Macropus eugenii	72.21	0.00e+00	819.00
IUUC-Mor-057243	Magnaporthe oryzae	32.81	8.00e-54	205.00
IUUC-Mpo-057439	Magnaporthe poae	34.13	2.00e-55	210.00
IUUC-Mtr-058457	Medicago truncatula	32.03	2.00e-52	200.00
IUUC-Mla-058929	Melampsora laricipopulina	30.39	2.00e-51	196.00
IUUC-Mga-060157	Meleagris gallopavo	74.32	0.00e+00	1091.00
IUUC-Mvi-060442	Microbotryum violaceum	32.76	5.00e-52	199.00
IUUC-Mmr-061062	Microcebus murinus	89.14	0.00e+00	1388.00
IUUC-Mdo-062798	Monodelphis domestica	77.58	0.00e+00	1150.00
IUUC-Mmu-064050	Mus musculus	80.35	0.00e+00	1215.00
IUUC-Mac-065619	Musa acuminata	32.99	7.00e-50	191.00
IUUC-Mpu-066554	Mustela putorius furo	84.99	0.00e+00	1240.00
IUUC-Mlu-068003	Myotis lucifugus	83.33	0.00e+00	1250.00
IUUC-Nfi-068612	Neosartorya fischeri	33.05	2.00e-57	217.00
IUUC-Ncr-068878	Neurospora crassa	33.59	3.00e-47	184.00
IUUC-Nle-069661	Nomascus leucogenys	95.74	0.00e+00	1464.00
IUUC-Opr-070944	Ochotona princeps	76.51	4.00e-170	591.00
IUUC-Ont-071266	Oreochromis niloticus	57.09	0.00e+00	762.00
IUUC-Oan-073442	Ornithorhynchus anatinus	77.33	0.00e+00	1075.00
IUUC-Ocu-073788	Oryctolagus cuniculus	77.69	0.00e+00	1065.00
IUUC-Oba-075085	Oryza barthii	32.23	4.00e-37	147.00
IUUC-Obr-076663	Oryza brachyantha	31.27	3.00e-46	179.00
IUUC-Ogl-076937	Oryza glaberrima	28.12	3.00e-43	169.00
IUUC-Ogu-078909	Oryza glumaepatula	29.74	1.00e-45	177.00
IUUC-Oin-079617	Oryza indica	29.03	6.00e-43	169.00
IUUC-Ome-081646	Oryza meridionalis	23.75	4.00e-23	102.00
IUUC-Oni-082914	Oryza nivara	29.15	2.00e-45	177.00
IUUC-Oru-084878	Oryza rufipogon	28.68	1.00e-45	177.00
IUUC-Osa-085822	Oryza sativa	28.46	2.00e-45	176.00
IUUC-Ola-086931	Oryzias latipes	67.44	0.00e+00	628.00
IUUC-Oga-088443	Otolemur garnettii	89.14	0.00e+00	1372.00
IUUC-Oar-089325	Ovis aries	81.46	0.00e+00	1117.00
IUUC-Pan-092551	Papio anubis	92.86	0.00e+00	1412.00
IUUC-Psi-093366	Pelodiscus sinensis	74.24	0.00e+00	690.00
IUUC-Pno-095136	Phaeosphaeria nodorum	33.42	2.00e-45	177.00
IUUC-Ppa-095574	Physcomitrella patens	34.78	3.00e-54	206.00
IUUC-Pfo-097462	Poecilia formosa	74.25	0.00e+00	655.00
IUUC-Pab-098547	Pongo abelii	95.86	0.00e+00	1462.00
IUUC-Pop-099529	Populus trichocarpa	34.54	5.00e-56	212.00
IUUC-Pca-101066	Procavia capensis	75.84	0.00e+00	1108.00
IUUC-Ppe-102110	Prunus persica	34.88	6.00e-54	204.00
IUUC-Pva-103015	Pteropus vampyrus	80.35	0.00e+00	1192.00
IUUC-Ptt-103998	Puccinia triticina	31.11	3.00e-47	183.00
IUUC-Pte-104417	Pyrenophora teres	32.58	4.00e-50	193.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	33.76	3.00e-50	193.00
IUUC-Rno-105533	Rattus norvegicus	81.00	0.00e+00	1214.00
IUUC-Sce-106160	Saccharomyces cerevisiae	26.34	3.00e-32	134.00
IUUC-Sha-106590	Sarcophilus harrisii	77.97	0.00e+00	1150.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	34.15	2.00e-53	203.00
IUUC-Spo-108353	Schizosaccharomyces pombe	35.97	2.00e-58	219.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	34.78	3.00e-53	203.00
IUUC-Smo-108842	Selaginella moellendorffii	33.21	4.00e-31	127.00
IUUC-Sit-110781	Setaria italica	30.57	1.00e-51	198.00
IUUC-Sly-111797	Solanum lycopersicum	32.90	1.00e-50	194.00
IUUC-Stu-112188	Solanum tuberosum	33.76	1.00e-51	197.00
IUUC-Sbi-114862	Sorghum bicolor	32.31	2.00e-43	170.00
IUUC-Sre-115162	Sporisorium reilianum	33.26	1.00e-59	224.00
IUUC-Ssc-115505	Sus scrofa	88.35	7.00e-147	513.00
IUUC-Tgu-116535	Taeniopygia guttata	73.77	0.00e+00	1054.00
IUUC-Tru-117542	Takifugu rubripes	55.08	0.00e+00	771.00
IUUC-Tni-120200	Tetraodon nigroviridis	56.08	0.00e+00	761.00
IUUC-Tca-121548	Theobroma cacao	33.97	8.00e-42	164.00
IUUC-Tre-122124	Trichoderma reesei	32.05	4.00e-56	213.00
IUUC-Tvi-122457	Trichoderma virens	33.24	3.00e-49	190.00
IUUC-Tae-125646	Triticum aestivum	32.90	2.00e-51	197.00
IUUC-Tme-127180	Tuber melanosporum	38.32	4.00e-65	242.00
IUUC-Tbe-127530	Tupaia belangeri	79.09	0.00e+00	933.00
IUUC-Ttr-128549	Tursiops truncatus	76.82	0.00e+00	1120.00
IUUC-Uma-129381	Ustilago maydis	32.32	1.00e-58	221.00
IUUC-Vda-129889	Verticillium dahliae	30.79	3.00e-48	187.00
IUUC-Vpa-130100	Vicugna pacos	78.46	0.00e+00	1144.00
IUUC-Vvi-131366	Vitis vinifera	33.59	4.00e-58	219.00
IUUC-Xtr-132048	Xenopus tropicalis	61.04	0.00e+00	855.00
IUUC-Xma-133593	Xiphophorus maculatus	74.73	0.00e+00	652.00
IUUC-Yli-134338	Yarrowia lipolytica	27.32	3.00e-31	130.00
IUUC-Zma-135586	Zea mays	29.72	7.00e-47	181.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence