iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116535

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01124185

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000004217.1	ENSTGUT00000004412.1	ENSTGUP00000004366.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.00e-68	228.9	404	783

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l+++  +   ++++++ +++++l+s+ +l++e++      k k+              a++p+
   Q: 404  GLINKGNWCYINATLQALVACPPMYHLMKS-IPMY-SKSQRPCTSTPMLDSFVRLMNEFTnmpvppKAKQAlgdkivrdirpgaAFEPT 490
           9*****************************.3333.33455799***************7777664333337888888999999***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk...................eknkpkeeeeeedkselsde.......aeek 133
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+                      ++ pkeee+ee+ + ++de       +   
   Q: 491  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLTlkkllsphnekvsvsngpeAQSVPKEEEQEEQGEGSEDEweqvgprN--- 576
           *9999999999966599********************4455688888888988888854445555554444444444466665552... PP
   S: 134  kkkknk...........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekc 211
                k           ++i+d+F+g+++ +++ ++  ++s + + f++l+l++++++ +   ++qd+Les +++e+++g    y++k 
   Q: 577  -----KssvtrqadfvqTPITDIFGGHIR-SVVYQQSSKESATLQLFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKT 652
           .....334444445666***********9.688999999*******************99...****************8....99999 PP
   S: 212  kkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYv 296
           k+++e +++l+l+klP+vL+lhLkRf ++++++++ k+ k++e+   L++s+ + sp  k+k    +++Y+L+avv+H+G s+ +GHY+
   Q: 653  KQEVEISRRLTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYTVDLEISKELLSPGVKSKIskgQRTYRLFAVVYHHGnSATGGHYT 740
           ****************************9998886.***************9888877666546669********************** PP
   S: 297  ayvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
           ++v +   + Wl++dD+ V++++ ++v++    +taY+l+Y++
   Q: 741  TDVFQIGLNgWLRIDDQAVRVIHHSQVVKAALeRTAYLLYYRQ 783
           *****87777*****************996658********97 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

YIFGEFSPDE FNQFFVTPRC SVELPPYNET VSCGIKSTGK FHDGEEYQRI EFGVNEVIET 60
QSSVLNNTDY SISSTLNPQA PEFILSCAPA QKTPDDALSD TNYNSIDCQF SDPTLALDSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATATTTTTG GGGAGTTCAG CCCTGATGAA TTTAATCAGT TCTTTGTGAC TCCACGATGC 60
TCTGTTGAGG TAAGATCTAC TTTAAACTTG TTTTAGAAAT AACATTTGAA AGCTCCATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	32.22	3.00e-47	182.00
IUUC-Aml-001584	Ailuropoda melanoleuca	76.67	0.00e+00	1117.00
IUUC-Atr-002927	Amborella trichopoda	34.70	3.00e-57	216.00
IUUC-Apl-003988	Anas platyrhynchos	90.23	0.00e+00	1368.00
IUUC-Aca-004461	Anolis carolinensis	93.41	4.00e-165	573.00
IUUC-Aly-006038	Arabidopsis lyrata	35.55	2.00e-54	206.00
IUUC-Ath-007328	Arabidopsis thaliana	35.29	1.00e-53	203.00
IUUC-Ago-007717	Ashbya gossypii	27.42	3.00e-43	169.00
IUUC-Acl-008188	Aspergillus clavatus	35.68	7.00e-62	231.00
IUUC-Afl-008456	Aspergillus flavus	36.72	2.00e-47	182.00
IUUC-Afu-009067	Aspergillus fumigatus	37.18	8.00e-65	241.00
IUUC-Ani-009483	Aspergillus nidulans	35.31	5.00e-61	229.00
IUUC-Ang-009639	Aspergillus niger	35.64	1.00e-61	231.00
IUUC-Aor-010040	Aspergillus oryzae	33.79	4.00e-60	226.00
IUUC-Ate-010310	Aspergillus terreus	34.35	2.00e-60	227.00
IUUC-Ame-011012	Astyanax mexicanus	74.20	2.00e-168	585.00
IUUC-Bgr-012311	Blumeria graminis	34.82	1.00e-45	177.00
IUUC-Bta-013299	Bos taurus	77.08	0.00e+00	1098.00
IUUC-Bci-013783	Botrytis cinerea	35.46	5.00e-58	219.00
IUUC-Bdi-015039	Brachypodium distachyon	31.15	1.00e-50	193.00
IUUC-Bol-015806	Brassica oleracea	36.46	7.00e-63	234.00
IUUC-Bra-017076	Brassica rapa	36.08	1.00e-63	236.00
IUUC-Cja-018715	Callithrix jacchus	76.17	0.00e+00	1134.00
IUUC-Cfa-020194	Canis familiaris	77.18	0.00e+00	1140.00
IUUC-Cpo-022272	Cavia porcellus	66.62	0.00e+00	902.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.00	8.00e-34	138.00
IUUC-Csa-023310	Chlorocebus sabaeus	77.30	0.00e+00	1152.00
IUUC-Cho-024966	Choloepus hoffmanni	72.84	0.00e+00	777.00
IUUC-Cin-025616	Ciona intestinalis	48.92	8.00e-110	390.00
IUUC-Csv-026043	Ciona savignyi	47.12	2.00e-100	358.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	32.84	1.00e-46	181.00
IUUC-Cne-026962	Cryptococcus neoformans	35.29	2.00e-50	194.00
IUUC-Cme-027113	Cyanidioschyzon merolae	30.91	1.00e-34	140.00
IUUC-Dre-028072	Danio rerio	77.04	0.00e+00	722.00
IUUC-Dno-029489	Dasypus novemcinctus	76.94	0.00e+00	1168.00
IUUC-Dor-031068	Dipodomys ordii	68.82	9.00e-132	463.00
IUUC-Dse-031553	Dothistroma septosporum	36.39	2.00e-57	216.00
IUUC-Dme-031759	Drosophila melanogaster	41.20	6.00e-83	302.00
IUUC-Ete-032549	Echinops telfairi	70.39	0.00e+00	754.00
IUUC-Eca-033380	Equus caballus	76.82	0.00e+00	1155.00
IUUC-Eeu-034818	Erinaceus europaeus	75.06	0.00e+00	1102.00
IUUC-Fca-035535	Felis catus	75.71	0.00e+00	1021.00
IUUC-Fal-036627	Ficedula albicollis	96.32	0.00e+00	1409.00
IUUC-Fox-037904	Fusarium oxysporum	35.64	8.00e-53	201.00
IUUC-Fso-038170	Fusarium solani	32.95	1.00e-51	198.00
IUUC-Gmo-039499	Gadus morhua	69.49	0.00e+00	663.00
IUUC-Ggr-040042	Gaeumannomyces graminis	34.26	2.00e-60	227.00
IUUC-Gga-040571	Gallus gallus	89.71	0.00e+00	1333.00
IUUC-Gac-041345	Gasterosteus aculeatus	76.08	0.00e+00	679.00
IUUC-Gma-044407	Glycine max	35.04	5.00e-58	218.00
IUUC-Ggo-044652	Gorilla gorilla	77.05	0.00e+00	1154.00
IUUC-Hsa-045864	Homo sapiens	76.92	0.00e+00	1152.00
IUUC-Hvu-047071	Hordeum vulgare	33.50	1.00e-54	207.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	81.03	0.00e+00	909.00
IUUC-Kpa-049132	Komagataella pastoris	31.10	2.00e-45	176.00
IUUC-Lch-050040	Latimeria chalumnae	72.44	0.00e+00	980.00
IUUC-Lpe-050772	Leersia perrieri	30.28	5.00e-17	82.00
IUUC-Loc-052449	Lepisosteus oculatus	75.29	0.00e+00	729.00
IUUC-Lma-053248	Leptosphaeria maculans	34.77	3.00e-56	213.00
IUUC-Laf-054121	Loxodonta africana	77.05	0.00e+00	1152.00
IUUC-Mcc-055514	Macaca mulatta	77.18	0.00e+00	1148.00
IUUC-Meu-056873	Macropus eugenii	72.21	0.00e+00	832.00
IUUC-Mor-057243	Magnaporthe oryzae	32.10	2.00e-57	217.00
IUUC-Mpo-057439	Magnaporthe poae	34.10	3.00e-60	226.00
IUUC-Mtr-058457	Medicago truncatula	34.02	6.00e-56	211.00
IUUC-Mla-058929	Melampsora laricipopulina	30.91	7.00e-55	208.00
IUUC-Mga-060157	Meleagris gallopavo	88.17	0.00e+00	1343.00
IUUC-Mvi-060442	Microbotryum violaceum	32.63	1.00e-54	208.00
IUUC-Mmr-061062	Microcebus murinus	75.66	0.00e+00	1148.00
IUUC-Mdo-062798	Monodelphis domestica	79.92	0.00e+00	1192.00
IUUC-Mmu-064050	Mus musculus	72.60	0.00e+00	1105.00
IUUC-Mac-065202	Musa acuminata	33.65	1.00e-51	196.00
IUUC-Mpu-066554	Mustela putorius furo	76.57	0.00e+00	1101.00
IUUC-Mlu-068003	Myotis lucifugus	76.82	0.00e+00	1145.00
IUUC-Nfi-068612	Neosartorya fischeri	36.39	4.00e-62	232.00
IUUC-Ncr-068878	Neurospora crassa	34.35	4.00e-50	193.00
IUUC-Nle-069661	Nomascus leucogenys	76.80	0.00e+00	1144.00
IUUC-Opr-070944	Ochotona princeps	76.33	1.00e-162	566.00
IUUC-Ont-071266	Oreochromis niloticus	59.07	0.00e+00	835.00
IUUC-Oan-073442	Ornithorhynchus anatinus	79.71	0.00e+00	1149.00
IUUC-Ocu-073788	Oryctolagus cuniculus	72.48	0.00e+00	998.00
IUUC-Oba-075085	Oryza barthii	34.05	3.00e-35	141.00
IUUC-Obr-076663	Oryza brachyantha	30.09	2.00e-45	176.00
IUUC-Ogl-076937	Oryza glaberrima	29.93	3.00e-48	185.00
IUUC-Ogu-078909	Oryza glumaepatula	30.72	3.00e-46	179.00
IUUC-Oin-079617	Oryza indica	30.96	4.00e-47	182.00
IUUC-Olo-081043	Oryza longistaminata	26.52	5.00e-24	105.00
IUUC-Ome-081646	Oryza meridionalis	25.71	4.00e-23	102.00
IUUC-Oni-082914	Oryza nivara	30.72	2.00e-46	180.00
IUUC-Oru-084878	Oryza rufipogon	30.72	2.00e-46	180.00
IUUC-Osa-085822	Oryza sativa	30.72	3.00e-50	192.00
IUUC-Ola-086931	Oryzias latipes	57.98	0.00e+00	800.00
IUUC-Oga-088443	Otolemur garnettii	75.54	0.00e+00	1138.00
IUUC-Oar-089325	Ovis aries	75.03	0.00e+00	1020.00
IUUC-Ptr-091584	Pan troglodytes	74.53	0.00e+00	1076.00
IUUC-Pan-092551	Papio anubis	75.16	0.00e+00	1108.00
IUUC-Psi-093366	Pelodiscus sinensis	83.94	0.00e+00	827.00
IUUC-Pno-095136	Phaeosphaeria nodorum	33.78	1.00e-48	187.00
IUUC-Ppa-095574	Physcomitrella patens	38.11	2.00e-61	229.00
IUUC-Pfo-097462	Poecilia formosa	57.18	0.00e+00	814.00
IUUC-Pab-098547	Pongo abelii	76.80	0.00e+00	1141.00
IUUC-Pop-099529	Populus trichocarpa	38.52	2.00e-62	233.00
IUUC-Pca-101066	Procavia capensis	68.85	0.00e+00	986.00
IUUC-Ppe-102110	Prunus persica	36.87	9.00e-60	223.00
IUUC-Pva-103015	Pteropus vampyrus	72.54	0.00e+00	1057.00
IUUC-Ptt-103998	Puccinia triticina	33.00	9.00e-54	204.00
IUUC-Pte-104417	Pyrenophora teres	32.93	1.00e-54	207.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	33.94	5.00e-53	202.00
IUUC-Rno-105533	Rattus norvegicus	72.76	0.00e+00	1097.00
IUUC-Sce-106160	Saccharomyces cerevisiae	26.11	5.00e-40	159.00
IUUC-Sha-106590	Sarcophilus harrisii	78.41	0.00e+00	1177.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	35.52	2.00e-55	209.00
IUUC-Spo-108353	Schizosaccharomyces pombe	35.73	2.00e-60	226.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	34.69	2.00e-57	217.00
IUUC-Smo-108842	Selaginella moellendorffii	35.36	3.00e-37	148.00
IUUC-Sit-110781	Setaria italica	32.94	2.00e-55	210.00
IUUC-Sly-111797	Solanum lycopersicum	35.20	1.00e-55	210.00
IUUC-Stu-112188	Solanum tuberosum	34.86	5.00e-56	211.00
IUUC-Sbi-114862	Sorghum bicolor	32.86	1.00e-42	167.00
IUUC-Sre-115162	Sporisorium reilianum	41.96	9.00e-46	178.00
IUUC-Ssc-115505	Sus scrofa	86.13	2.00e-150	524.00
IUUC-Tru-117542	Takifugu rubripes	58.47	0.00e+00	840.00
IUUC-Tni-120200	Tetraodon nigroviridis	58.19	0.00e+00	827.00
IUUC-Tca-121548	Theobroma cacao	33.23	3.00e-43	169.00
IUUC-Tre-122124	Trichoderma reesei	35.86	8.00e-62	231.00
IUUC-Tvi-122457	Trichoderma virens	34.02	2.00e-54	207.00
IUUC-Tae-125646	Triticum aestivum	34.68	3.00e-56	213.00
IUUC-Tme-127180	Tuber melanosporum	38.71	2.00e-68	253.00
IUUC-Tbe-127530	Tupaia belangeri	65.94	0.00e+00	894.00
IUUC-Ttr-128549	Tursiops truncatus	69.71	0.00e+00	1017.00
IUUC-Uma-129381	Ustilago maydis	31.75	3.00e-62	233.00
IUUC-Vda-129889	Verticillium dahliae	33.51	6.00e-53	202.00
IUUC-Vpa-130100	Vicugna pacos	71.57	0.00e+00	1016.00
IUUC-Vvi-131366	Vitis vinifera	36.29	6.00e-63	234.00
IUUC-Xtr-132048	Xenopus tropicalis	65.59	0.00e+00	961.00
IUUC-Xma-133593	Xiphophorus maculatus	77.04	0.00e+00	701.00
IUUC-Yli-134338	Yarrowia lipolytica	28.50	6.00e-33	135.00
IUUC-Zma-135255	Zea mays	31.32	2.00e-55	210.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence