iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068892

Ensembl Protein ID

EAA28645

UniProt Accession

Q7S028; Q7S028_NEUCR

Genbank Protein ID

EAA28645.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM002242

Gene Name

NCU10066

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU10066	EAA28645	EAA28645

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-36	122.4	56	92
UBD/Beta-Prp	5.60e-80	267.7	9	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+l t ++l
   Q: 56   HDGPVRGVDFhKTqPLFVSGGDDYKIKVWSLQTRRCL 92
           99*********4459****************999997 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++s+ + ++f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ v+f+++++++v+g++D+ ikvw+l+t+ c+ tl+gh d+++++ f+ 
   Q: 9    TKFESKSSRAKGIAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEEHDGPVRGVDFHKTQPLFVSGGDDYKIKVWSLQTRRCLFTLNGHLDYIRTVFFHH 109
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...............................ktgkllrt 174
           +  ++vs+s+d+tir+w++++++ l  t +gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                               +t+ +++ 
   Q: 110  ELPWIVSASDDQTIRIWNWQNRSLLC-TMTGHNHYVMCAQFHPKEDLIVSASLDQTVRVWDIsglrkkhsaptsmsfedqvarananqtdmfgNTDAVVKF 209
           *************************9.**********************************************************9999999777777776 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavl 273
             +gh++ v++++f+++++ +vs+++d+ +klw +++++   v+t++gh +n +   f+p++++++s+++D++ir+Wdl ++++++t++++n++++ +a+ 
   Q: 210  VLEGHDRGVNWVAFHPTMPLIVSAGDDRLIKLWRMSETKAweVDTCRGHFQNASGCLFHPHQDLILSAGEDKTIRVWDLNKRTVVNTFKRENDRIWVIAA- 309
           6777********************************888778**********************************************************. PP
   S: 274  sfgdnvlvlgsedskvniwklkknep 299
           +++ n +++g  d+ v+++kl++++p
   Q: 310  HPEINLFAAG-HDNGVMVFKLERERP 334
           6666555555.478*******98775 PP

Organism

Neurospora crassa

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MQASSGMLTK FESKSSRAKG IAFHPKRPWI LVSLHSSTIQ LWDYRMGTLI DRFEEHDGPV 60
RGVDFHKTQP LFVSGGDDYK IKVWSLQTRR CLFTLNGHLD YIRTVFFHHE LPWIVSASDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACAGGTAAG GGTAGTATGG ATCCTAACAA GTGGAATTGA AGCCGCCGCC CGAGACCGTC 60
CTGTCCACTC CAGCACCTCA GCTCCGTTAG TTGATTGTGA GTGCCTGGCA TCCATCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

ncr:NCU10066

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	56.05	0.00e+00	981.00
IUUC-Aml-001758	Ailuropoda melanoleuca	49.20	0.00e+00	1216.00
IUUC-Atr-002493	Amborella trichopoda	55.84	0.00e+00	964.00
IUUC-Apl-003385	Anas platyrhynchos	43.72	0.00e+00	897.00
IUUC-Aca-005154	Anolis carolinensis	72.82	1.00e-93	333.00
IUUC-Aly-006020	Arabidopsis lyrata	55.82	0.00e+00	967.00
IUUC-Ath-007360	Arabidopsis thaliana	55.82	0.00e+00	971.00
IUUC-Ago-007992	Ashbya gossypii	50.61	0.00e+00	1216.00
IUUC-Acl-008027	Aspergillus clavatus	76.53	0.00e+00	1919.00
IUUC-Afl-008644	Aspergillus flavus	76.76	0.00e+00	1917.00
IUUC-Afu-008964	Aspergillus fumigatus	77.25	0.00e+00	1954.00
IUUC-Ani-009379	Aspergillus nidulans	83.69	0.00e+00	1520.00
IUUC-Ang-009756	Aspergillus niger	77.34	0.00e+00	1932.00
IUUC-Aor-010174	Aspergillus oryzae	76.68	0.00e+00	1913.00
IUUC-Ate-010302	Aspergillus terreus	77.50	0.00e+00	1967.00
IUUC-Ame-011229	Astyanax mexicanus	56.36	0.00e+00	1009.00
IUUC-Bgr-012300	Blumeria graminis	76.59	0.00e+00	1919.00
IUUC-Bta-012524	Bos taurus	49.56	0.00e+00	1208.00
IUUC-Bci-013781	Botrytis cinerea	83.14	0.00e+00	2101.00
IUUC-Bdi-014549	Brachypodium distachyon	46.21	0.00e+00	1111.00
IUUC-Bol-015925	Brassica oleracea	56.42	0.00e+00	972.00
IUUC-Bra-016978	Brassica rapa	55.93	0.00e+00	965.00
IUUC-Cel-018115	Caenorhabditis elegans	51.65	0.00e+00	896.00
IUUC-Cja-019107	Callithrix jacchus	48.36	0.00e+00	1191.00
IUUC-Cfa-020675	Canis familiaris	48.82	0.00e+00	1186.00
IUUC-Cpo-021813	Cavia porcellus	49.56	0.00e+00	1222.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	56.97	0.00e+00	999.00
IUUC-Csa-023523	Chlorocebus sabaeus	49.48	0.00e+00	1229.00
IUUC-Cho-024704	Choloepus hoffmanni	37.63	3.00e-146	511.00
IUUC-Cin-025572	Ciona intestinalis	47.36	0.00e+00	1158.00
IUUC-Csv-025864	Ciona savignyi	54.89	0.00e+00	951.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	87.25	0.00e+00	2170.00
IUUC-Cne-027053	Cryptococcus neoformans	54.77	0.00e+00	1327.00
IUUC-Cme-027222	Cyanidioschyzon merolae	40.49	2.00e-142	499.00
IUUC-Dre-027421	Danio rerio	49.64	0.00e+00	1205.00
IUUC-Dno-029303	Dasypus novemcinctus	49.56	0.00e+00	1223.00
IUUC-Dor-030290	Dipodomys ordii	46.50	1.00e-146	512.00
IUUC-Dse-031543	Dothistroma septosporum	74.73	0.00e+00	1806.00
IUUC-Dme-031945	Drosophila melanogaster	56.01	0.00e+00	955.00
IUUC-Ete-032873	Echinops telfairi	47.01	0.00e+00	1061.00
IUUC-Eca-033773	Equus caballus	48.28	0.00e+00	1169.00
IUUC-Eeu-034874	Erinaceus europaeus	38.02	7.00e-164	569.00
IUUC-Fca-035739	Felis catus	49.12	0.00e+00	1195.00
IUUC-Fal-037263	Ficedula albicollis	46.36	0.00e+00	1072.00
IUUC-Fox-037738	Fusarium oxysporum	86.10	0.00e+00	2211.00
IUUC-Fso-038153	Fusarium solani	86.75	0.00e+00	2211.00
IUUC-Gmo-039602	Gadus morhua	46.88	0.00e+00	1100.00
IUUC-Ggr-039931	Gaeumannomyces graminis	86.24	0.00e+00	2111.00
IUUC-Gga-040590	Gallus gallus	49.48	0.00e+00	1214.00
IUUC-Gac-041318	Gasterosteus aculeatus	47.58	0.00e+00	1172.00
IUUC-Gma-043894	Glycine max	55.89	0.00e+00	981.00
IUUC-Ggo-045029	Gorilla gorilla	49.12	0.00e+00	1219.00
IUUC-Hsa-046078	Homo sapiens	49.12	0.00e+00	1220.00
IUUC-Hvu-047556	Hordeum vulgare	46.65	0.00e+00	1122.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	41.09	0.00e+00	660.00
IUUC-Kpa-049256	Komagataella pastoris	53.73	0.00e+00	1350.00
IUUC-Lch-049706	Latimeria chalumnae	49.36	0.00e+00	1185.00
IUUC-Lpe-051316	Leersia perrieri	55.81	0.00e+00	975.00
IUUC-Loc-051867	Lepisosteus oculatus	38.54	0.00e+00	793.00
IUUC-Lma-053138	Leptosphaeria maculans	75.31	0.00e+00	1906.00
IUUC-Laf-053510	Loxodonta africana	49.48	0.00e+00	1216.00
IUUC-Mcc-055836	Macaca mulatta	49.20	0.00e+00	1218.00
IUUC-Meu-056238	Macropus eugenii	51.91	0.00e+00	710.00
IUUC-Mor-057172	Magnaporthe oryzae	86.27	0.00e+00	2195.00
IUUC-Mpo-057300	Magnaporthe poae	85.67	0.00e+00	2137.00
IUUC-Mtr-058248	Medicago truncatula	47.93	0.00e+00	1139.00
IUUC-Mla-059019	Melampsora laricipopulina	56.45	0.00e+00	1410.00
IUUC-Mga-059499	Meleagris gallopavo	49.48	0.00e+00	1209.00
IUUC-Mvi-060336	Microbotryum violaceum	55.05	0.00e+00	1389.00
IUUC-Mmr-061102	Microcebus murinus	49.20	0.00e+00	1208.00
IUUC-Mdo-062594	Monodelphis domestica	49.56	0.00e+00	1228.00
IUUC-Mmu-063736	Mus musculus	48.64	0.00e+00	1209.00
IUUC-Mac-065398	Musa acuminata	44.65	0.00e+00	1016.00
IUUC-Mpu-066701	Mustela putorius furo	48.56	0.00e+00	1206.00
IUUC-Mlu-067392	Myotis lucifugus	49.12	0.00e+00	1208.00
IUUC-Nfi-068270	Neosartorya fischeri	77.00	0.00e+00	1932.00
IUUC-Nle-069634	Nomascus leucogenys	60.12	0.00e+00	869.00
IUUC-Opr-070952	Ochotona princeps	37.64	1.00e-165	575.00
IUUC-Ont-072488	Oreochromis niloticus	47.66	0.00e+00	1179.00
IUUC-Ocu-074211	Oryctolagus cuniculus	49.40	0.00e+00	1219.00
IUUC-Oba-075761	Oryza barthii	55.93	0.00e+00	976.00
IUUC-Obr-076429	Oryza brachyantha	55.70	0.00e+00	975.00
IUUC-Ogl-077364	Oryza glaberrima	55.93	0.00e+00	976.00
IUUC-Ogu-078257	Oryza glumaepatula	55.93	0.00e+00	975.00
IUUC-Oin-079274	Oryza indica	55.81	0.00e+00	975.00
IUUC-Olo-080466	Oryza longistaminata	56.08	0.00e+00	967.00
IUUC-Ome-081993	Oryza meridionalis	55.94	0.00e+00	936.00
IUUC-Oni-082874	Oryza nivara	55.93	0.00e+00	975.00
IUUC-Opu-083885	Oryza punctata	55.93	0.00e+00	976.00
IUUC-Oru-084274	Oryza rufipogon	55.81	0.00e+00	974.00
IUUC-Osa-085565	Oryza sativa	55.81	0.00e+00	974.00
IUUC-Ola-086921	Oryzias latipes	48.16	0.00e+00	1177.00
IUUC-Olu-087639	Ostreococcus lucimarinus	48.91	0.00e+00	1165.00
IUUC-Oga-087991	Otolemur garnettii	47.25	0.00e+00	1152.00
IUUC-Oar-089590	Ovis aries	49.64	0.00e+00	1224.00
IUUC-Ptr-090808	Pan troglodytes	49.12	0.00e+00	1219.00
IUUC-Pan-092475	Papio anubis	49.12	0.00e+00	1215.00
IUUC-Psi-093044	Pelodiscus sinensis	51.75	0.00e+00	850.00
IUUC-Pno-094839	Phaeosphaeria nodorum	74.83	0.00e+00	1824.00
IUUC-Ppa-095254	Physcomitrella patens	49.84	0.00e+00	1192.00
IUUC-Pfo-097493	Poecilia formosa	48.59	0.00e+00	1175.00
IUUC-Pab-098497	Pongo abelii	49.40	0.00e+00	1228.00
IUUC-Pop-100086	Populus trichocarpa	49.11	0.00e+00	1142.00
IUUC-Pca-100413	Procavia capensis	53.23	2.00e-178	617.00
IUUC-Ppe-101899	Prunus persica	56.24	0.00e+00	975.00
IUUC-Pva-102126	Pteropus vampyrus	47.76	0.00e+00	1155.00
IUUC-Pgr-103376	Puccinia graminis	56.07	0.00e+00	1417.00
IUUC-Ptt-103978	Puccinia triticina	50.92	0.00e+00	1203.00
IUUC-Pte-104126	Pyrenophora teres	73.24	0.00e+00	1805.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	66.91	0.00e+00	1398.00
IUUC-Rno-105428	Rattus norvegicus	49.56	0.00e+00	1222.00
IUUC-Sce-106464	Saccharomyces cerevisiae	49.88	0.00e+00	1193.00
IUUC-Sha-107301	Sarcophilus harrisii	49.15	0.00e+00	1200.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	52.95	0.00e+00	1347.00
IUUC-Spo-108217	Schizosaccharomyces pombe	54.84	0.00e+00	1413.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	82.80	0.00e+00	2098.00
IUUC-Smo-109582	Selaginella moellendorffii	56.19	0.00e+00	1000.00
IUUC-Sit-109697	Setaria italica	55.74	0.00e+00	974.00
IUUC-Sly-111447	Solanum lycopersicum	46.64	0.00e+00	1115.00
IUUC-Stu-112564	Solanum tuberosum	46.84	0.00e+00	1130.00
IUUC-Sar-113313	Sorex araneus	37.88	1.00e-161	561.00
IUUC-Sbi-114388	Sorghum bicolor	55.74	0.00e+00	974.00
IUUC-Sre-115209	Sporisorium reilianum	62.51	0.00e+00	1132.00
IUUC-Ssc-115933	Sus scrofa	49.56	0.00e+00	1222.00
IUUC-Tgu-117109	Taeniopygia guttata	42.78	6.00e-90	322.00
IUUC-Tru-117772	Takifugu rubripes	47.27	0.00e+00	1161.00
IUUC-Tsy-119105	Tarsius syrichta	47.62	0.00e+00	930.00
IUUC-Tni-120556	Tetraodon nigroviridis	35.41	0.00e+00	672.00
IUUC-Tca-120918	Theobroma cacao	56.66	0.00e+00	983.00
IUUC-Tre-121951	Trichoderma reesei	84.38	0.00e+00	2113.00
IUUC-Tvi-122359	Trichoderma virens	84.06	0.00e+00	2146.00
IUUC-Tae-125527	Triticum aestivum	56.05	0.00e+00	981.00
IUUC-Tur-126754	Triticum urartu	55.93	0.00e+00	981.00
IUUC-Tme-127170	Tuber melanosporum	73.71	0.00e+00	1929.00
IUUC-Tbe-127882	Tupaia belangeri	62.82	2.00e-120	425.00
IUUC-Ttr-128217	Tursiops truncatus	47.68	0.00e+00	1152.00
IUUC-Uma-129337	Ustilago maydis	62.28	0.00e+00	1125.00
IUUC-Vda-129828	Verticillium dahliae	83.74	0.00e+00	2111.00
IUUC-Vpa-130537	Vicugna pacos	49.08	0.00e+00	1202.00
IUUC-Vvi-130958	Vitis vinifera	56.71	0.00e+00	985.00
IUUC-Xtr-132857	Xenopus tropicalis	47.00	0.00e+00	1122.00
IUUC-Xma-133138	Xiphophorus maculatus	48.75	0.00e+00	1180.00
IUUC-Yli-134399	Yarrowia lipolytica	60.90	0.00e+00	1088.00
IUUC-Zma-135612	Zea mays	46.24	0.00e+00	1112.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence