iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 3    vtnedlkcLeegeflnDviidfylkylvlekl.kkekverihifssffykklkq.kerr.........rvktwtrkvdlfekdlifvpineaaHWsla 89
           v  +dl+cL+++e+l+  +++fy+ +l ++   +++    +h+f+++fykkl+    ++         r ++w + +dlf k +if+pi+e+ HWsl+
   Q: 345  VCLKDLECLAPREYLTSPVMNFYMRFLQQQISsSNQISADCHFFNTYFYKKLSDaVTYKgndkdaffvRFRRWWKGIDLFRKAYIFIPIHEDLHWSLV 442
           6679*********************888877734445568*************955577999************************************ PP
   S: 90   vvcf......kkksilllDSlrgasksnvvkklreylev....evkkkskre..fskeklkg.......snpkvpqQkNssDCGvyvlqyvesl 164
           +vc+      +  +il+lDSl  +s++++v++++++l++      ++ ++ +  +s++++k+       ++++vpqQkN++DCG +vl +++ +
   Q: 443  IVCIpdkkdeSGLTILHLDSLGLHSRKSIVENVKRFLKDewnyLNQDDYSLDlpISEKVWKNlprriseAVVQVPQQKNDFDCGPFVLFFIKRF 536
           ****5544433447*******999***************5532112222222225677777522211114566*****************9876 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins. Cleaves precursors of SUM1 and SUM2, but not of SUM3 or SUM5. Able to release SUM1 and SUM2 from conjugates, but unable to cleave SUM3. Protease activity mainly directed at deconjugating SUM1 and SUM2 from their target proteins. Regulates salt stress responses and flowering time. Redundant with ULP1C.

Protein Sequence
(Fasta)

MTKRKKEVID VDCSEKKDFV IDWSSAMDKE DEVPELEIVN TTKPTPPPPP TFFSDDQTDS 60
PKLLTDRDLD EQLERKKAIL TLGPGLPDKG EKIRLKIADL EEEKQRRVLE GSKMEVDRSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAAAATCT CTTTCTTTTG TGGATTGCGA AAAAGAGTCA AACATTTTCA CAAGCAAATA 60
ATTGCTCAAG TTACAAAATT ACCAAACTTT ACGAAAACAA AAAATAGAAA AAAATCCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0016607--C:nuclear speck
GO:0005634--C:nucleus
GO:0004175--F:endopeptidase activity
GO:0016929--F:SUMO-specific protease activity
GO:0016926--P:protein desumoylation
GO:0009651--P:response to salt stress
GO:0010228--P:vegetative to reproductive phase transition of meristem

KEGG

ath:AT1G60220

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006464	Arabidopsis lyrata	85.43	0.00e+00	860.00
IUUC-Ago-007729	Ashbya gossypii	25.09	4.00e-17	83.20
IUUC-Ate-010553	Aspergillus terreus	30.93	4.00e-12	67.00
IUUC-Bdi-014070	Brachypodium distachyon	52.03	5.00e-80	291.00
IUUC-Bol-015752	Brassica oleracea	65.43	0.00e+00	704.00
IUUC-Bra-017215	Brassica rapa	66.55	0.00e+00	719.00
IUUC-Cgl-026623	Colletotrichum gloeosporioides	27.27	5.00e-15	76.60
IUUC-Gma-043594	Glycine max	39.54	3.00e-99	355.00
IUUC-Mtr-057643	Medicago truncatula	56.09	2.00e-96	346.00
IUUC-Mvi-060469	Microbotryum violaceum	28.36	9.00e-11	62.80
IUUC-Mac-064836	Musa acuminata	53.09	3.00e-91	328.00
IUUC-Nfi-068345	Neosartorya fischeri	30.67	3.00e-17	84.00
IUUC-Obr-076911	Oryza brachyantha	47.52	2.00e-74	272.00
IUUC-Ogl-077206	Oryza glaberrima	47.18	8.00e-76	277.00
IUUC-Oin-080139	Oryza indica	47.18	8.00e-76	277.00
IUUC-Ome-081672	Oryza meridionalis	51.87	8.00e-73	267.00
IUUC-Opu-083969	Oryza punctata	46.08	8.00e-74	270.00
IUUC-Osa-086048	Oryza sativa	47.18	1.00e-75	276.00
IUUC-Olu-087762	Ostreococcus lucimarinus	33.33	1.00e-39	157.00
IUUC-Ppa-095571	Physcomitrella patens	36.81	2.00e-43	169.00
IUUC-Pgr-103328	Puccinia graminis	31.53	3.00e-12	67.80
IUUC-Pte-104039	Pyrenophora teres	37.86	1.00e-12	68.60
IUUC-Pyt-104790	Pyrenophora triticirepentis	36.89	7.00e-12	65.10
IUUC-Sce-106359	Saccharomyces cerevisiae	26.39	4.00e-16	80.10
IUUC-Sit-110110	Setaria italica	47.41	8.00e-73	267.00
IUUC-Sly-111546	Solanum lycopersicum	53.06	4.00e-91	327.00
IUUC-Tca-121259	Theobroma cacao	45.56	8.00e-115	406.00
IUUC-Tae-123912	Triticum aestivum	47.39	2.00e-78	286.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence