iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-064756

Ensembl Protein ID

GSMUA_Achr8P14580_001

UniProt Accession

M0TQG1; M0TQG1_MUSAM

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr8G14580_001	GSMUA_Achr8T14580_001	GSMUA_Achr8P14580_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	7.40e-123	410.5	150	460
E3 adaptor/Cullin RING/DCX/DWD	1.20e-24	86.2	285	316
UBD/Beta-Prp	3.00e-40	139.1	286	455

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           ++ ldap++ dd+ylnLldW++ nvl++aLg++vylw+a++g+ s+l  + ++   vtsvsw ++g ++avG +++ v+++D ++++ 
   Q: 150  DRTLDAPDIVDDYYLNLLDWGTGNVLSIALGNTVYLWDASDGSTSELVTVdDDAGPVTSVSWAPDGRHIAVGLNSSDVQLWDSASNRL 237
           689**********************************************9778889******************************** PP
   S: 89   vrtl.tghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse..... 170
           +rtl   h +rvg+L+Wn+++ls+G+ dg+i+ +dvrv+ + ++t+++h+qevCGlkw+ ++++LasGGnDn v++wd s  +     
   Q: 238  LRTLrGVHGSRVGSLAWNNNILSTGGMDGKIVNNDVRVRSHVVQTYRGHQQEVCGLKWSGSGQQLASGGNDNLVHIWDVSMASanppr 325
           ****55599*********************************************************************9987777755 PP
   S: 171  ....PlkkfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwky 254
                 ++ ++h aavka+aw+P+q++lLasGGG  Drcikfwnt tga+l+++dtgsqvcsllw kk++el+s+hGf++n++tlwky
   Q: 326  gqnqWFHRLDDHMAAVKALAWCPFQSNLLASGGGGGDRCIKFWNTHTGACLNSVDTGSQVCSLLWNKKERELLSSHGFTQNQLTLWKY 413
           44333566779***************************************************************************** PP
   S: 255  pslskvaelkgheaRvlslalspdgeaivtaagDetlrfwklfdkkk 301
           ps+ ++ael+gh++Rvl +a spdg ++++aagDetlrfw++f + +
   Q: 414  PSMVRIAELTGHTSRVLFMAQSPDGCTVASAAGDETLRFWNVFGTPE 460
           *******************************************8765 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH+ +v++l++  s+  l+sG++D+ +++WD+
   Q: 285  GHQQEVCGLKWsgSGQQLASGGNDNLVHIWDV 316
           8**********976699**************7 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdls.........tgkcvhtlkghedsvlslsfsp.sgdklvsG..shdrtirvwdletg 126
           h++ev  +k+s +g+ l++g++D+++++wd+s         +++ +h l  h + v +l+++p +++ l+sG  + dr i+ w+++tg
   Q: 286  HQQEVCGLKWSGSGQQLASGGNDNLVHIWDVSmasanpprgQNQWFHRLDDHMAAVKALAWCPfQSNLLASGggGGDRCIKFWNTHTG 373
           8999***********************************************************8889***972257************ PP
   S: 127  qcleetlsghdgvvncvvvhpdg.nllvs.GslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
            cl+++++g +  v+++ +++++  ll s G++ +++ lW+ +++  + +ltg ht++v  ++ +++g  ++s++ d t+++w++
   Q: 374  ACLNSVDTGSQ--VCSLLWNKKErELLSShGFTQNQLTLWKYPSMVRIAELTG-HTSRVLFMAQSPDGCTVASAAGDETLRFWNV 455
           ****9999998..9*******99666655699********************9.*****************************97 PP

Organism

Musa acuminata

Protein Sequence
(Fasta)

MDAGSSSSSI SSEKRRMSSR RPLQDVPSRP FLPSMHTTSR NPSWRQSVSH VLLLFGDRFI 60
PDRSAMDMDV AYYLLTQTRK EKENAVPASP SKEAYRKLLA ENLLKNRTRI LAFHSKPPEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGCAG GGAGCTCCTC TTCTTCTATT TCTTCAGAGA AGCGTCGAAT GTCATCTCGT 60
CGCCCTCTCC AAGACGTCCC ATCCAGGCCT TTCCTGCCTT CGATGCACAC CACCTCCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cne-026872	Cryptococcus neoformans	43.16	8.00e-86	310.00
IUUC-Dse-031391	Dothistroma septosporum	47.85	3.00e-95	342.00
IUUC-Fox-037850	Fusarium oxysporum	46.05	2.00e-91	329.00
IUUC-Lma-052998	Leptosphaeria maculans	45.48	6.00e-93	334.00
IUUC-Pno-094809	Phaeosphaeria nodorum	44.84	8.00e-94	337.00
IUUC-Pte-104142	Pyrenophora teres	45.18	3.00e-93	335.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	45.18	3.00e-93	335.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	47.54	1.00e-89	322.00
IUUC-Tme-126905	Tuber melanosporum	47.29	6.00e-94	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence