iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pop-099651

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

WD-40 repeat family protein

Genbank Nucleotide ID

CM000355

Gene Name

POPTRDRAFT_738273; POPTR_0019s03850g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0019s03850	POPTR_0019s03850.1	POPTR_0019s03850.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-26	92.6	257	287
E3 adaptor/Cullin RING/APC_C/CDC20	6.20e-124	414.3	122	426
UBD/Beta-Prp	7.60e-41	141.3	152	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gHt +v++l++  s+  l+sG++D+ i++WD
   Q: 257  GHTQEVCGLKWsaSGQQLASGGNDNLIHIWD 287
           8***********87799************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrt 91
           e+ ldap+l ddfylnLldW+s+nvla+aLgs+vylw+a++g+ s+l  + +e+  vtsv+w ++g ++a+G ++++++++D ++++++rt
   Q: 122  ERTLDAPDLVDDFYLNLLDWGSSNVLAIALGSTVYLWDASDGSTSELVTVdDEDGPVTSVNWAPDGRHIAIGLNNSHIQLWDSASNRQLRT 212
           689***********************************************667778*********************************** PP
   S: 92   l.tghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse......Plkkf 175
           l  gh +rvg+++Wn+++l++G+ dg+i  +dvr++ + ++t+++h+qevCGlkw+ ++++LasGGnDn +++wd s+         l++ 
   Q: 213  LkGGHRSRVGSMAWNNHILTTGGMDGQIINNDVRIRSHIVETYRGHTQEVCGLKWSASGQQLASGGNDNLIHIWDRSTALsnsatqWLHRL 303
           *778***********************************************************************9876555666688999 PP
   S: 176  kehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           ++h++avka+aw+P+q +lLasGGG  D+ ikfwnt tga+l++idtgsqvcsllw k+++el+s+hGf++n++t+wkyps+ k+ael+gh
   Q: 304  EDHTSAVKALAWCPFQGNLLASGGGGGDKSIKFWNTHTGACLNSIDTGSQVCSLLWNKNERELLSSHGFTQNQLTVWKYPSMVKMAELTGH 394
           9****************************************************************************************** PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfd 298
           ++Rvl++a spdg +++taagDetlrfw++f 
   Q: 395  TSRVLYMAQSPDGCTVATAAGDETLRFWNVFG 426
           ******************************96 PP

UBD/Beta-Prp

   S: 112  Gshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsld 201
           Gs   t+ +wd + g+ +e  t + +dg v++v++ pdg+ ++ G +++ ++lWd+++++ lrtl+ggh ++v s++++     l +g++d
   Q: 152  GS---TVYLWDASDGSTSELvTVDDEDGPVTSVNWAPDGRHIAIGLNNSHIQLWDSASNRQLRTLKGGHRSRVGSMAWNN--HILTTGGMD 237
           44...999*****9988876699999****************************************************99..89******* PP
   S: 202  gtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsg 254
           g+++  d++ ++++v+t++ght+ v+ ++ s  ++ l+sg+ D+ i iWd  + 
   Q: 238  GQIINNDVRiRSHIVETYRGHTQEVCGLKWSASGQQLASGGNDNLIHIWDRSTA 291
           *************************************************97665 PP

Organism

Populus trichocarpa

Protein Sequence
(Fasta)

MNTSSSLKAQ SRFPLQQQFL PRTNSKENLD RFIPNRSAMD MDYARFMLTE GRKGKENPTV 60
NSPSREAYRK QLADSLNMNR TRILAFKNKP PAPVELMPQD HSHHHHQPKT AKPRRHIPQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATCAAATC AAATACTCTG TAAAGATCAA GAACACATCG CCTAGACCCC CTCTTCCTCC 60
TTCTCTTTCT CTGACTTTCT CTCCTTCTGT CTTTTTTCCT TCTTTCTTAT TAATTGCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

pop:POPTR_0019s03850g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002628	Amborella trichopoda	69.80	2.00e-179	621.00
IUUC-Dre-028026	Danio rerio	43.02	2.00e-102	365.00
IUUC-Fso-038375	Fusarium solani	47.98	3.00e-96	345.00
IUUC-Pte-104142	Pyrenophora teres	46.88	7.00e-95	340.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	47.17	6.00e-95	341.00
IUUC-Sha-107472	Sarcophilus harrisii	45.56	2.00e-99	355.00
IUUC-Tru-118184	Takifugu rubripes	43.35	2.00e-92	332.00
IUUC-Tre-122211	Trichoderma reesei	42.07	8.00e-97	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence