iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090553

Ensembl Protein ID

ENSPTRP00000018646.4

UniProt Accession

H2QG55; H2QG55_PANTR

Genbank Protein ID

ENSPTRP00000018646

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03117159

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000010882.5	ENSPTRT00000020162.4	ENSPTRP00000018646.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-27	93.4	153	190
UBD/Beta-Prp	4.70e-55	186.8	495	752

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 583
           67899*******************************************99887899**************9997888999********* PP
   S: 98   lslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgg 178
           ++++f  ++   ++s ++d+ i     ++g+   +        ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +g 
   Q: 584  TAIKFAGNRdIQMISCGADKSIYFRSAQQGSDGLHfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGSQG- 671
           *******885789********998666666555544332112222233445677778****************988888888888888. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlr 252
           +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ ++s++f+ + ++l+++s D  ++iW       ++ 
   Q: 672  DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWhlgpeitNCM 752
           999999999**************************************************************6644444443 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAAVGSGGYA RNDAGEKLPS VMAGVPARRG QSSPPPAPPI CLRRRTRLST ASEETVQNRV 60
SLEKVLGITA QNSSGLTCDP STGHVAYLAG CVVVILDPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCCCGCGG CTGTTCGCTG TTCCAGTGGG TCGTGGCGCT GGCGGCAGCG GCGGTTAGGG 60
GATGTAACGG TCGCCCGGCT CCGGCGTGAC GATGGCGGCC GTAGGGTCCG GAGGCTATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005813--C:centrosome
GO:0071011--C:precatalytic spliceosome
GO:0000922--C:spindle pole
GO:0005682--C:U5 snRNP
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	82.40	0.00e+00	2368.00
IUUC-Atr-003165	Amborella trichopoda	33.65	7.00e-122	431.00
IUUC-Apl-003236	Anas platyrhynchos	61.36	0.00e+00	967.00
IUUC-Aca-004935	Anolis carolinensis	71.45	0.00e+00	1010.00
IUUC-Aly-006434	Arabidopsis lyrata	29.58	2.00e-54	207.00
IUUC-Ath-007624	Arabidopsis thaliana	30.10	8.00e-91	328.00
IUUC-Ago-007823	Ashbya gossypii	22.76	6.00e-11	63.20
IUUC-Acl-008257	Aspergillus clavatus	21.22	2.00e-22	101.00
IUUC-Afu-008757	Aspergillus fumigatus	21.52	3.00e-29	124.00
IUUC-Ani-009489	Aspergillus nidulans	23.78	8.00e-12	66.20
IUUC-Ang-009797	Aspergillus niger	24.88	7.00e-11	63.20
IUUC-Ate-010425	Aspergillus terreus	23.47	1.00e-25	112.00
IUUC-Ame-011306	Astyanax mexicanus	60.03	0.00e+00	904.00
IUUC-Bgr-012083	Blumeria graminis	25.28	1.00e-21	99.00
IUUC-Bta-013336	Bos taurus	79.72	0.00e+00	2226.00
IUUC-Bci-013828	Botrytis cinerea	22.42	6.00e-33	136.00
IUUC-Bol-016347	Brassica oleracea	30.36	3.00e-86	313.00
IUUC-Bra-017959	Brassica rapa	31.05	6.00e-89	322.00
IUUC-Cel-018592	Caenorhabditis elegans	28.78	6.00e-74	273.00
IUUC-Cja-019094	Callithrix jacchus	90.62	0.00e+00	2613.00
IUUC-Cfa-020529	Canis familiaris	82.41	0.00e+00	2373.00
IUUC-Cpo-021970	Cavia porcellus	87.07	0.00e+00	1660.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	28.38	1.00e-13	71.60
IUUC-Csa-024161	Chlorocebus sabaeus	94.81	0.00e+00	2722.00
IUUC-Cho-024310	Choloepus hoffmanni	84.80	0.00e+00	1167.00
IUUC-Cin-025412	Ciona intestinalis	52.41	3.00e-58	217.00
IUUC-Csv-026079	Ciona savignyi	41.60	2.00e-76	278.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.85	7.00e-25	109.00
IUUC-Dre-028678	Danio rerio	56.78	0.00e+00	1002.00
IUUC-Dno-029933	Dasypus novemcinctus	75.61	0.00e+00	2114.00
IUUC-Dor-031147	Dipodomys ordii	77.86	0.00e+00	2129.00
IUUC-Dse-031501	Dothistroma septosporum	30.71	1.00e-23	105.00
IUUC-Dme-032179	Drosophila melanogaster	48.16	0.00e+00	743.00
IUUC-Ete-033108	Echinops telfairi	60.56	0.00e+00	930.00
IUUC-Eca-033675	Equus caballus	81.08	0.00e+00	2281.00
IUUC-Eeu-034798	Erinaceus europaeus	89.17	0.00e+00	901.00
IUUC-Fca-035826	Felis catus	81.65	0.00e+00	2398.00
IUUC-Fal-037354	Ficedula albicollis	60.73	0.00e+00	963.00
IUUC-Fox-037952	Fusarium oxysporum	21.45	1.00e-24	108.00
IUUC-Fso-038440	Fusarium solani	23.83	1.00e-33	138.00
IUUC-Gmo-039644	Gadus morhua	54.62	0.00e+00	733.00
IUUC-Ggr-039729	Gaeumannomyces graminis	22.67	5.00e-24	106.00
IUUC-Gga-040202	Gallus gallus	56.51	1.00e-100	359.00
IUUC-Gac-042491	Gasterosteus aculeatus	55.93	0.00e+00	806.00
IUUC-Gma-043644	Glycine max	31.52	2.00e-100	360.00
IUUC-Ggo-045152	Gorilla gorilla	98.62	0.00e+00	2783.00
IUUC-Hsa-045891	Homo sapiens	98.88	0.00e+00	2807.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	91.58	0.00e+00	1546.00
IUUC-Kpa-049269	Komagataella pastoris	26.05	1.00e-11	65.50
IUUC-Lch-049669	Latimeria chalumnae	58.23	0.00e+00	1014.00
IUUC-Loc-052488	Lepisosteus oculatus	55.91	0.00e+00	1023.00
IUUC-Lma-053327	Leptosphaeria maculans	29.85	4.00e-18	87.00
IUUC-Laf-053992	Loxodonta africana	79.25	0.00e+00	2292.00
IUUC-Mcc-054994	Macaca mulatta	96.45	0.00e+00	2712.00
IUUC-Meu-056815	Macropus eugenii	78.70	0.00e+00	1415.00
IUUC-Mor-057027	Magnaporthe oryzae	27.06	8.00e-12	66.20
IUUC-Mtr-058383	Medicago truncatula	30.64	3.00e-50	192.00
IUUC-Mga-059325	Meleagris gallopavo	61.70	0.00e+00	956.00
IUUC-Mmr-060693	Microcebus murinus	80.29	0.00e+00	2232.00
IUUC-Mdo-063007	Monodelphis domestica	61.69	0.00e+00	1758.00
IUUC-Mmu-064067	Mus musculus	75.45	0.00e+00	2150.00
IUUC-Mpu-066532	Mustela putorius furo	82.87	0.00e+00	2413.00
IUUC-Mlu-066982	Myotis lucifugus	78.14	0.00e+00	2141.00
IUUC-Nfi-068613	Neosartorya fischeri	21.90	2.00e-29	125.00
IUUC-Ncr-068758	Neurospora crassa	22.37	4.00e-29	124.00
IUUC-Nle-070042	Nomascus leucogenys	85.38	0.00e+00	2332.00
IUUC-Opr-070397	Ochotona princeps	79.65	0.00e+00	2286.00
IUUC-Ont-072247	Oreochromis niloticus	58.69	0.00e+00	886.00
IUUC-Oan-073644	Ornithorhynchus anatinus	58.10	0.00e+00	820.00
IUUC-Ocu-074274	Oryctolagus cuniculus	80.59	0.00e+00	2217.00
IUUC-Ola-087185	Oryzias latipes	56.94	0.00e+00	887.00
IUUC-Oga-088577	Otolemur garnettii	82.83	0.00e+00	2373.00
IUUC-Oar-090117	Ovis aries	77.37	0.00e+00	2153.00
IUUC-Pan-092559	Papio anubis	94.61	0.00e+00	1502.00
IUUC-Psi-093710	Pelodiscus sinensis	63.24	0.00e+00	1382.00
IUUC-Pma-094285	Petromyzon marinus	60.28	0.00e+00	944.00
IUUC-Pno-094837	Phaeosphaeria nodorum	24.86	4.00e-19	90.50
IUUC-Ppa-095596	Physcomitrella patens	36.67	5.00e-136	479.00
IUUC-Pfo-096375	Poecilia formosa	57.38	0.00e+00	825.00
IUUC-Pab-098510	Pongo abelii	95.54	0.00e+00	2650.00
IUUC-Pop-099155	Populus trichocarpa	31.25	4.00e-96	346.00
IUUC-Pca-100323	Procavia capensis	71.99	0.00e+00	1338.00
IUUC-Pva-102895	Pteropus vampyrus	81.78	0.00e+00	2322.00
IUUC-Pte-104373	Pyrenophora teres	25.43	8.00e-14	72.80
IUUC-Pyt-104804	Pyrenophora triticirepentis	25.72	5.00e-14	73.60
IUUC-Rno-105598	Rattus norvegicus	75.88	0.00e+00	2188.00
IUUC-Sha-107013	Sarcophilus harrisii	67.04	0.00e+00	1802.00
IUUC-Ssl-108471	Sclerotinia sclerotiorum	23.04	3.00e-19	90.90
IUUC-Smo-109134	Selaginella moellendorffii	36.95	3.00e-133	469.00
IUUC-Sly-110969	Solanum lycopersicum	29.71	4.00e-89	322.00
IUUC-Stu-112838	Solanum tuberosum	30.05	2.00e-50	193.00
IUUC-Sar-113261	Sorex araneus	74.98	0.00e+00	2065.00
IUUC-Ssc-115317	Sus scrofa	80.75	0.00e+00	2229.00
IUUC-Tgu-117055	Taeniopygia guttata	62.41	0.00e+00	952.00
IUUC-Tru-118066	Takifugu rubripes	59.30	0.00e+00	855.00
IUUC-Tsy-118799	Tarsius syrichta	92.12	0.00e+00	865.00
IUUC-Tni-120316	Tetraodon nigroviridis	55.91	0.00e+00	782.00
IUUC-Tca-121475	Theobroma cacao	30.54	4.00e-95	343.00
IUUC-Tre-122008	Trichoderma reesei	23.27	4.00e-30	127.00
IUUC-Tme-127128	Tuber melanosporum	23.67	5.00e-33	136.00
IUUC-Tbe-127555	Tupaia belangeri	93.60	0.00e+00	1016.00
IUUC-Ttr-128722	Tursiops truncatus	79.89	0.00e+00	2263.00
IUUC-Vda-129957	Verticillium dahliae	22.91	2.00e-29	125.00
IUUC-Vpa-130392	Vicugna pacos	69.09	1.00e-108	387.00
IUUC-Vvi-131035	Vitis vinifera	33.24	2.00e-103	370.00
IUUC-Xtr-131789	Xenopus tropicalis	59.76	0.00e+00	989.00
IUUC-Xma-134296	Xiphophorus maculatus	57.68	0.00e+00	867.00
IUUC-Yli-134437	Yarrowia lipolytica	25.68	2.00e-16	81.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence