iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020561

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03013614

Gene Name

LOC610206

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000030591.1	ENSCAFT00000011950.2	ENSCAFP00000040182.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.00e-47	159.2	7	139

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R+ ke+++l ++p++gi+a+p+++ +   ++v+i Gp+d+p+egg+Fkle+ +pe+YP+ +Pkv+f+tki+hPnv++ G++Cl+ilk  
   Q: 7    RIIKETQRLLAEPVPGIKAEPDES-NARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILK-- 92
           899*********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkk 136
           +kWspal++++vllsiq+ll+ p p++pl +++ae++k+n+++  ++
   Q: 93   DKWSPALQIRTVLLSIQALLSAPTPDDPLANDVAEQWKTNEAQAIET 139
           ****************************************9976655 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAGLPRRIIK ETQRLLAEPV PGIKAEPDES NARYFHVVIA GPQDSPFEGG TFKLELFLPE 60
EYPMAAPKVR FMTKIYHPNV DKLGRICLDI LKDKWSPALQ IRTVLLSIQA LLSAPTPDDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGGGC TGCCCCGCAG GATTATCAAG GAAACCCAGC GTTTGCTGGC AGAACCAGTT 60
CCTGGCATTA AAGCAGAACC AGATGAGAGC AACGCCCGTT ATTTTCATGT GGTCATTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0001650--C:fibrillar center
GO:0005634--C:nucleus
GO:0031372--C:UBC13-MMS2 complex
GO:0035370--C:UBC13-UEV1A complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0000729--P:DNA double-strand break processing
GO:0000724--P:double-strand break repair via homologous recombination
GO:0016574--P:histone ubiquitination
GO:0045739--P:positive regulation of DNA repair
GO:0031058--P:positive regulation of histone modification
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination
GO:0033182--P:regulation of histone ubiquitination
GO:0050852--P:T cell receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003469	Anas platyrhynchos	97.26	1.00e-82	297.00
IUUC-Aca-005051	Anolis carolinensis	99.34	7.00e-87	311.00
IUUC-Ago-007837	Ashbya gossypii	74.40	1.00e-53	201.00
IUUC-Ani-009482	Aspergillus nidulans	70.67	2.00e-63	234.00
IUUC-Ate-010254	Aspergillus terreus	70.55	7.00e-62	229.00
IUUC-Ame-010742	Astyanax mexicanus	97.37	7.00e-85	305.00
IUUC-Bta-012636	Bos taurus	99.34	7.00e-87	311.00
IUUC-Cel-018119	Caenorhabditis elegans	87.92	2.00e-74	270.00
IUUC-Cja-019108	Callithrix jacchus	99.34	7.00e-87	311.00
IUUC-Cpo-022280	Cavia porcellus	96.03	5.00e-83	299.00
IUUC-Csa-023860	Chlorocebus sabaeus	92.11	9.00e-80	288.00
IUUC-Cho-024459	Choloepus hoffmanni	99.34	7.00e-87	311.00
IUUC-Csv-025952	Ciona savignyi	72.30	1.00e-59	221.00
IUUC-Cme-027100	Cyanidioschyzon merolae	65.10	5.00e-56	209.00
IUUC-Dre-027814	Danio rerio	97.37	7.00e-85	305.00
IUUC-Dno-030059	Dasypus novemcinctus	97.37	4.00e-85	306.00
IUUC-Dme-032097	Drosophila melanogaster	79.47	4.00e-72	263.00
IUUC-Ete-032369	Echinops telfairi	99.34	7.00e-87	311.00
IUUC-Eca-033230	Equus caballus	99.34	7.00e-87	311.00
IUUC-Fca-036161	Felis catus	94.74	1.00e-82	298.00
IUUC-Fal-036781	Ficedula albicollis	96.05	4.00e-84	303.00
IUUC-Fox-037840	Fusarium oxysporum	71.23	4.00e-60	223.00
IUUC-Fso-038118	Fusarium solani	71.23	2.00e-60	223.00
IUUC-Gmo-039561	Gadus morhua	92.76	4.00e-82	296.00
IUUC-Ggr-039807	Gaeumannomyces graminis	72.11	6.00e-62	229.00
IUUC-Gga-041024	Gallus gallus	99.34	7.00e-87	311.00
IUUC-Gac-042450	Gasterosteus aculeatus	91.39	2.00e-80	290.00
IUUC-Ggo-044660	Gorilla gorilla	98.68	4.00e-86	309.00
IUUC-Hsa-045881	Homo sapiens	99.34	7.00e-87	311.00
IUUC-Itr-048350	Ictidomys tridecemlineatus	91.45	7.00e-78	282.00
IUUC-Kpa-049285	Komagataella pastoris	69.59	3.00e-62	229.00
IUUC-Loc-052205	Lepisosteus oculatus	97.37	5.00e-85	306.00
IUUC-Lma-053056	Leptosphaeria maculans	71.92	7.00e-62	229.00
IUUC-Mcc-054863	Macaca mulatta	99.34	7.00e-87	311.00
IUUC-Mor-057014	Magnaporthe oryzae	71.92	2.00e-60	224.00
IUUC-Mpo-057586	Magnaporthe poae	72.11	8.00e-62	228.00
IUUC-Mla-058920	Melampsora laricipopulina	69.39	2.00e-60	224.00
IUUC-Mmr-061167	Microcebus murinus	99.34	7.00e-87	311.00
IUUC-Mdo-062701	Monodelphis domestica	99.34	7.00e-87	311.00
IUUC-Mmu-064070	Mus musculus	99.34	7.00e-87	311.00
IUUC-Mac-064742	Musa acuminata	80.27	2.00e-70	257.00
IUUC-Ncr-068643	Neurospora crassa	71.43	2.00e-61	227.00
IUUC-Nle-070146	Nomascus leucogenys	99.34	7.00e-87	311.00
IUUC-Opr-070232	Ochotona princeps	77.63	9.00e-63	231.00
IUUC-Ont-072369	Oreochromis niloticus	94.00	9.00e-82	295.00
IUUC-Oan-073174	Ornithorhynchus anatinus	95.39	5.00e-83	299.00
IUUC-Ocu-074712	Oryctolagus cuniculus	99.34	7.00e-87	311.00
IUUC-Ola-087083	Oryzias latipes	94.00	1.00e-81	294.00
IUUC-Oar-090440	Ovis aries	98.68	3.00e-86	310.00
IUUC-Ptr-090572	Pan troglodytes	99.34	7.00e-87	311.00
IUUC-Pan-092503	Papio anubis	97.37	4.00e-85	306.00
IUUC-Pno-094838	Phaeosphaeria nodorum	71.62	8.00e-63	232.00
IUUC-Pfo-096074	Poecilia formosa	94.67	4.00e-82	296.00
IUUC-Pab-097778	Pongo abelii	99.34	7.00e-87	311.00
IUUC-Pca-100334	Procavia capensis	82.89	2.00e-72	263.00
IUUC-Ppe-101149	Prunus persica	79.59	9.00e-70	255.00
IUUC-Pva-102979	Pteropus vampyrus	99.34	7.00e-87	311.00
IUUC-Pte-104137	Pyrenophora teres	70.55	5.00e-61	226.00
IUUC-Pyt-104513	Pyrenophora triticirepentis	70.55	5.00e-61	226.00
IUUC-Rno-105927	Rattus norvegicus	98.68	2.00e-86	310.00
IUUC-Sce-106178	Saccharomyces cerevisiae	69.59	5.00e-61	226.00
IUUC-Sha-107493	Sarcophilus harrisii	99.34	7.00e-87	311.00
IUUC-Ssc-116096	Sus scrofa	99.34	7.00e-87	311.00
IUUC-Tru-117903	Takifugu rubripes	93.38	5.00e-81	292.00
IUUC-Tni-120038	Tetraodon nigroviridis	93.38	5.00e-81	292.00
IUUC-Tre-121979	Trichoderma reesei	73.29	2.00e-61	228.00
IUUC-Tvi-122515	Trichoderma virens	72.60	8.00e-61	225.00
IUUC-Ttr-128808	Tursiops truncatus	96.05	2.00e-83	300.00
IUUC-Vda-129810	Verticillium dahliae	70.55	5.00e-60	223.00
IUUC-Vpa-130221	Vicugna pacos	90.65	1.00e-68	251.00
IUUC-Xtr-132366	Xenopus tropicalis	96.10	6.00e-84	302.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence