iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069712

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01182511

Gene Name

UBE2K

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000017116.2	ENSNLET00000021823.2	ENSNLEP00000020782.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.90e-44	150.8	31	156
UBD/Alpha-Helix/UBA	8.90e-11	41.6	171	209

Active Site

Position(s)	Description	Evidence
102	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 11   kdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsv 98
           k+++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+ilk  ++W +a+++
   Q: 31   KTSKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDILK--DQWAAAMTL 116
           567899********.9***************************************************99********9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 117  RTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 156
           *************************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+e+l++MGFdr++++ aL + ++++e A+e+Ll+
   Q: 171  EYTRKIENLCAMGFDRNAVIVALSSKSWDVETATELLLS 209
           5788*********************************97 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MKEGVSKFFI GNTLGVFLAD ITNIYFLFIF KTSKNQIKVD LVDENFTELR GEIAGPPDTP 60
YEGGRYQLEI KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAAGAGG GGGTTTCAAA ATTTTTTATA GGTAATACTT TAGGCGTTTT TCTTGCTGAC 60
ATAACTAACA TTTATTTTCT GTTTATTTTT AAGACGAGCA AAAATCAAAT TAAAGTAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0035458--P:cellular response to interferon-beta
GO:0010994--P:free ubiquitin chain polymerization
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0070936--P:protein K48-linked ubiquitination

KEGG

nle:100582790

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	66.67	3.00e-25	108.00
IUUC-Aml-001286	Ailuropoda melanoleuca	98.89	1.00e-97	348.00
IUUC-Atr-003063	Amborella trichopoda	51.46	1.00e-37	148.00
IUUC-Apl-004122	Anas platyrhynchos	100.00	2.00e-95	340.00
IUUC-Aca-004565	Anolis carolinensis	99.45	1.00e-98	352.00
IUUC-Aly-006390	Arabidopsis lyrata	51.72	9.00e-42	162.00
IUUC-Ath-006637	Arabidopsis thaliana	50.00	5.00e-39	153.00
IUUC-Acl-008189	Aspergillus clavatus	55.65	3.00e-26	111.00
IUUC-Afl-008489	Aspergillus flavus	44.57	7.00e-27	113.00
IUUC-Afu-008850	Aspergillus fumigatus	41.71	5.00e-27	114.00
IUUC-Ani-009361	Aspergillus nidulans	57.26	1.00e-24	106.00
IUUC-Ang-009548	Aspergillus niger	51.43	6.00e-25	107.00
IUUC-Aor-010105	Aspergillus oryzae	44.57	7.00e-27	113.00
IUUC-Ate-010389	Aspergillus terreus	43.48	3.00e-27	115.00
IUUC-Ame-011454	Astyanax mexicanus	96.67	7.00e-96	342.00
IUUC-Bgr-012255	Blumeria graminis	54.76	1.00e-31	129.00
IUUC-Bta-012992	Bos taurus	98.89	1.00e-97	348.00
IUUC-Bci-013806	Botrytis cinerea	50.00	3.00e-35	141.00
IUUC-Bdi-015024	Brachypodium distachyon	53.61	5.00e-38	150.00
IUUC-Bol-015985	Brassica oleracea	51.72	3.00e-42	164.00
IUUC-Bra-016805	Brassica rapa	51.72	3.00e-42	164.00
IUUC-Cel-018353	Caenorhabditis elegans	52.54	8.00e-50	189.00
IUUC-Cja-019051	Callithrix jacchus	98.33	7.00e-97	345.00
IUUC-Cfa-020016	Canis familiaris	98.89	1.00e-97	348.00
IUUC-Cpo-022026	Cavia porcellus	98.89	1.00e-97	348.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	50.83	6.00e-40	156.00
IUUC-Csa-023059	Chlorocebus sabaeus	98.89	1.00e-97	348.00
IUUC-Cho-024276	Choloepus hoffmanni	95.92	3.00e-73	266.00
IUUC-Cin-025598	Ciona intestinalis	61.93	3.00e-50	191.00
IUUC-Csv-025831	Ciona savignyi	63.07	2.00e-49	188.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	50.00	1.00e-32	132.00
IUUC-Cne-027068	Cryptococcus neoformans	44.26	8.00e-39	153.00
IUUC-Dre-028139	Danio rerio	96.67	7.00e-96	342.00
IUUC-Dno-029169	Dasypus novemcinctus	91.96	2.00e-98	350.00
IUUC-Dor-030382	Dipodomys ordii	83.33	3.00e-76	277.00
IUUC-Dse-031335	Dothistroma septosporum	60.17	1.00e-35	142.00
IUUC-Dme-032003	Drosophila melanogaster	68.79	4.00e-61	226.00
IUUC-Ete-032868	Echinops telfairi	88.89	5.00e-76	276.00
IUUC-Eca-033428	Equus caballus	98.89	1.00e-97	348.00
IUUC-Eeu-035103	Erinaceus europaeus	72.66	8.00e-49	185.00
IUUC-Fca-035366	Felis catus	98.89	1.00e-97	348.00
IUUC-Fal-037016	Ficedula albicollis	98.89	1.00e-97	348.00
IUUC-Fox-037969	Fusarium oxysporum	46.20	2.00e-32	132.00
IUUC-Fso-038296	Fusarium solani	46.11	9.00e-34	136.00
IUUC-Gmo-039135	Gadus morhua	95.56	1.00e-94	338.00
IUUC-Ggr-039768	Gaeumannomyces graminis	50.00	9.00e-24	103.00
IUUC-Gga-041018	Gallus gallus	99.44	4.00e-98	350.00
IUUC-Gac-041503	Gasterosteus aculeatus	96.11	2.00e-95	341.00
IUUC-Gma-042779	Glycine max	52.91	7.00e-41	159.00
IUUC-Ggo-045032	Gorilla gorilla	98.89	1.00e-97	348.00
IUUC-Hsa-046490	Homo sapiens	98.89	1.00e-97	348.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	98.89	1.00e-97	348.00
IUUC-Lch-050588	Latimeria chalumnae	69.19	1.00e-76	278.00
IUUC-Lpe-051070	Leersia perrieri	53.01	4.00e-29	120.00
IUUC-Loc-052549	Lepisosteus oculatus	97.22	3.00e-96	343.00
IUUC-Lma-052949	Leptosphaeria maculans	57.72	7.00e-36	143.00
IUUC-Laf-053688	Loxodonta africana	99.44	2.00e-97	347.00
IUUC-Mcc-055606	Macaca mulatta	98.89	1.00e-97	348.00
IUUC-Mor-056946	Magnaporthe oryzae	42.05	4.00e-22	98.20
IUUC-Mpo-057441	Magnaporthe poae	51.02	7.00e-24	103.00
IUUC-Mtr-058002	Medicago truncatula	52.33	6.00e-41	160.00
IUUC-Mla-059007	Melampsora laricipopulina	46.15	2.00e-36	145.00
IUUC-Mga-059254	Meleagris gallopavo	100.00	3.00e-98	350.00
IUUC-Mvi-060346	Microbotryum violaceum	42.54	7.00e-31	126.00
IUUC-Mmr-061211	Microcebus murinus	98.89	1.00e-97	348.00
IUUC-Mdo-062458	Monodelphis domestica	97.78	4.00e-95	340.00
IUUC-Mmu-063648	Mus musculus	98.89	1.00e-97	348.00
IUUC-Mac-065447	Musa acuminata	53.61	8.00e-39	152.00
IUUC-Mpu-066407	Mustela putorius furo	98.89	5.00e-97	347.00
IUUC-Mlu-067682	Myotis lucifugus	99.45	6.00e-99	352.00
IUUC-Nfi-068517	Neosartorya fischeri	42.21	3.00e-27	114.00
IUUC-Ncr-068749	Neurospora crassa	53.97	8.00e-36	143.00
IUUC-Opr-070651	Ochotona princeps	98.89	1.00e-97	348.00
IUUC-Ont-071595	Oreochromis niloticus	96.11	2.00e-95	341.00
IUUC-Oan-073058	Ornithorhynchus anatinus	99.32	2.00e-78	283.00
IUUC-Ocu-074939	Oryctolagus cuniculus	98.89	1.00e-97	348.00
IUUC-Oba-075530	Oryza barthii	53.94	3.00e-29	121.00
IUUC-Obr-076838	Oryza brachyantha	53.99	1.00e-28	119.00
IUUC-Ogl-077606	Oryza glaberrima	53.94	3.00e-29	121.00
IUUC-Ogu-078238	Oryza glumaepatula	53.94	3.00e-29	121.00
IUUC-Oin-079643	Oryza indica	53.94	6.00e-29	120.00
IUUC-Ome-081274	Oryza meridionalis	53.94	3.00e-29	121.00
IUUC-Oni-082651	Oryza nivara	53.94	3.00e-29	121.00
IUUC-Opu-083933	Oryza punctata	53.94	6.00e-29	120.00
IUUC-Oru-085054	Oryza rufipogon	53.94	6.00e-29	120.00
IUUC-Osa-085716	Oryza sativa	53.94	6.00e-29	120.00
IUUC-Ola-087043	Oryzias latipes	96.11	2.00e-95	341.00
IUUC-Olu-087846	Ostreococcus lucimarinus	48.86	9.00e-41	159.00
IUUC-Oga-088897	Otolemur garnettii	91.46	2.00e-98	350.00
IUUC-Oar-089673	Ovis aries	98.34	2.00e-97	347.00
IUUC-Ptr-091295	Pan troglodytes	98.89	1.00e-97	348.00
IUUC-Pan-092034	Papio anubis	98.34	8.00e-98	348.00
IUUC-Psi-093498	Pelodiscus sinensis	98.89	1.00e-97	348.00
IUUC-Pma-094115	Petromyzon marinus	87.22	5.00e-85	306.00
IUUC-Pno-095102	Phaeosphaeria nodorum	56.10	1.00e-36	145.00
IUUC-Ppa-095326	Physcomitrella patens	48.85	5.00e-37	147.00
IUUC-Pfo-096940	Poecilia formosa	96.11	2.00e-95	340.00
IUUC-Pab-098279	Pongo abelii	98.89	1.00e-97	348.00
IUUC-Pop-099543	Populus trichocarpa	52.30	5.00e-42	163.00
IUUC-Pca-100782	Procavia capensis	98.33	1.00e-95	342.00
IUUC-Ppe-101789	Prunus persica	52.00	6.00e-36	144.00
IUUC-Pva-102147	Pteropus vampyrus	99.04	4.00e-52	196.00
IUUC-Pte-104370	Pyrenophora teres	56.91	2.00e-35	142.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	56.91	3.00e-35	141.00
IUUC-Rno-104984	Rattus norvegicus	98.89	1.00e-97	348.00
IUUC-Sce-106394	Saccharomyces cerevisiae	45.09	6.00e-33	133.00
IUUC-Sha-106848	Sarcophilus harrisii	99.45	3.00e-98	350.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	45.19	1.00e-38	152.00
IUUC-Smo-109656	Selaginella moellendorffii	50.87	7.00e-38	149.00
IUUC-Sit-110639	Setaria italica	52.41	6.00e-37	146.00
IUUC-Sly-110978	Solanum lycopersicum	52.30	3.00e-42	164.00
IUUC-Stu-112088	Solanum tuberosum	52.30	1.00e-42	165.00
IUUC-Sar-113285	Sorex araneus	83.80	8.00e-76	275.00
IUUC-Sbi-113986	Sorghum bicolor	52.41	8.00e-37	146.00
IUUC-Ssc-116314	Sus scrofa	98.89	1.00e-97	348.00
IUUC-Tgu-117427	Taeniopygia guttata	99.44	8.00e-98	348.00
IUUC-Tru-118618	Takifugu rubripes	91.11	2.00e-90	324.00
IUUC-Tsy-119208	Tarsius syrichta	98.89	6.00e-98	349.00
IUUC-Tni-119667	Tetraodon nigroviridis	96.67	7.00e-96	342.00
IUUC-Tca-121446	Theobroma cacao	52.87	2.00e-42	164.00
IUUC-Tre-122053	Trichoderma reesei	39.88	2.00e-29	122.00
IUUC-Tvi-122533	Trichoderma virens	38.95	6.00e-29	120.00
IUUC-Tae-125119	Triticum aestivum	54.22	1.00e-30	125.00
IUUC-Tme-127024	Tuber melanosporum	53.57	2.00e-37	149.00
IUUC-Tbe-127752	Tupaia belangeri	97.28	3.00e-97	347.00
IUUC-Ttr-128287	Tursiops truncatus	99.44	3.00e-97	346.00
IUUC-Vda-129947	Verticillium dahliae	42.20	2.00e-30	125.00
IUUC-Vpa-130481	Vicugna pacos	98.89	1.00e-97	348.00
IUUC-Vvi-131429	Vitis vinifera	49.43	7.00e-39	153.00
IUUC-Xtr-132710	Xenopus tropicalis	80.77	2.00e-83	301.00
IUUC-Xma-134308	Xiphophorus maculatus	95.56	7.00e-95	339.00
IUUC-Yli-134523	Yarrowia lipolytica	48.30	2.00e-32	132.00
IUUC-Zma-135733	Zea mays	51.12	3.00e-35	140.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence