iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107715

Ensembl Protein ID

EEB07787

UniProt Accession

B6K1G6; CFD1_SCHJY

Genbank Protein ID

EEB07787.2

Protein Name

Probable cytosolic Fe-S cluster assembly factor SJAG_02895

Genbank Nucleotide ID

KE651166

Gene Name

SJAG_02895

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_02895	EEB07787	EEB07787

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-35	115.3	375	405
UBD/Beta-Prp	8.60e-47	157.7	345	608

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+++v c+a+ +d  +l+++s+D+++ +W+
   Q: 375  GHENEVKCVAWsHDgVYLATCSRDKSVWIWE 405
           8***********888***************8 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvtt..gkllrslsgheaevtavkfspdgkilvtgseDrtikvw...dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrt 117
           +++la +s d+t+ +++  +  + +++ l+ghe+ev++v +s+dg +l+t+s+D+ + +w   + + ++c+ +l++h+++v  ++++p++d lvsGs d+t
   Q: 345  RPVLAIASFDATVSIYEKIDddWECVAALEGHENEVKCVAWSHDGVYLATCSRDKSVWIWeamEDDEFDCLAVLQEHTQDVKVVAWHPKDDLLVSGSYDNT 445
           6899************996511566***********************************755555*********************************** PP
   S: 118  irvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl....................ktgkllrtl..tgghtdsvyslsfdsngkel 195
           ir w  + + ++++  l+ h+++v+ ++++pdg+ll+sG   + v +W                      + + +l+    +   t++vy l ++++ + +
   Q: 446  IRFWRDDGDDWVQTcELTSHTSTVWALNFSPDGRLLASGDGEGEVFIWEKlvsnedaartpstnilrpslEEEWCLKAVlpRT-FTEPVYTLGWKDDHTLC 545
           *************999*********************************99************99776665555554447765.99***********9999 PP
   S: 196  vsgsldgtvklwdlq...tgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsg 254
           +sg++ gt+ l+ ++   ++   ++l++    v+ +++    nd rl+sg++Dg  ++W l   
   Q: 546  ASGAE-GTIGLFAYEddvSTWHTVSLKEKAHDVYEINTIawTNDSRLLSGGDDGLCNVWKLSEA 608
           99985.89******9888555578888888888888876669*****************76654 PP

Organism

Schizosaccharomyces japonicus

Functional Description
(View)

Fusion protein of two essential components of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. May form a heterotetramer with nubp35, functioning as a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (By similarity).

Protein Sequence
(Fasta)

MENVKHIILV LSGKGGVGKS SVTTQLALSL HETPFYSRKL RIGVLDIDLT GPSIPRMFGM 60
DAETHRIHQS SSGWVPVYTD ETKEIGLMSL AFLLSSKNDS VVWRGPKKAA MIRQFVSDVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAACTGGT CGAGTAAAAG GTTTGAAGGA GGAATCGGGG CGATTTCCTG TTTGTTTTCG 60
AGAACTGTTT TGTTTTTTTC CTCGTTCAAA TTAAGGTTAT CTAAGTTCGC CTATCGATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0004--4Fe-4S
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0408--Iron
KW-0411--Iron-sulfur
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR019591--Mrp/NBP35_ATP-bd
IPR000808--Mrp_CS
IPR028600--NUBP2/Cfd1_eukaryotes
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR033756--YlxH/NBP35

PROSITE

PS01215--MRP
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF10609--ParA
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0005634--C:nucleus
GO:0051539--F:4 iron, 4 sulfur cluster binding
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	41.39	2.00e-49	188.00
IUUC-Aml-001317	Ailuropoda melanoleuca	38.73	8.00e-47	178.00
IUUC-Atr-003029	Amborella trichopoda	41.11	1.00e-59	221.00
IUUC-Aly-006458	Arabidopsis lyrata	36.57	9.00e-57	211.00
IUUC-Ath-006671	Arabidopsis thaliana	36.29	9.00e-56	208.00
IUUC-Ago-007820	Ashbya gossypii	43.27	1.00e-66	244.00
IUUC-Acl-008042	Aspergillus clavatus	32.79	2.00e-51	194.00
IUUC-Afl-008639	Aspergillus flavus	34.70	7.00e-57	212.00
IUUC-Afu-008899	Aspergillus fumigatus	32.18	2.00e-50	191.00
IUUC-Ani-009453	Aspergillus nidulans	35.55	9.00e-58	215.00
IUUC-Ang-009758	Aspergillus niger	37.99	4.00e-55	206.00
IUUC-Aor-010212	Aspergillus oryzae	34.70	7.00e-57	212.00
IUUC-Ate-010314	Aspergillus terreus	36.66	6.00e-59	219.00
IUUC-Ame-010676	Astyanax mexicanus	39.88	2.00e-56	210.00
IUUC-Bgr-012095	Blumeria graminis	31.96	5.00e-44	169.00
IUUC-Bta-012884	Bos taurus	39.14	1.00e-48	184.00
IUUC-Bci-013622	Botrytis cinerea	30.99	4.00e-40	157.00
IUUC-Bdi-014614	Brachypodium distachyon	38.84	2.00e-57	214.00
IUUC-Bol-016439	Brassica oleracea	37.75	9.00e-55	205.00
IUUC-Bra-016830	Brassica rapa	38.42	2.00e-56	210.00
IUUC-Cel-018709	Caenorhabditis elegans	35.65	2.00e-46	177.00
IUUC-Cja-019822	Callithrix jacchus	39.13	1.00e-47	181.00
IUUC-Cfa-020823	Canis familiaris	39.02	2.00e-47	180.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	39.54	2.00e-52	197.00
IUUC-Csa-023754	Chlorocebus sabaeus	39.31	1.00e-46	178.00
IUUC-Cin-025395	Ciona intestinalis	36.07	7.00e-57	211.00
IUUC-Csv-025943	Ciona savignyi	37.65	6.00e-57	212.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	31.74	1.00e-45	175.00
IUUC-Cne-026939	Cryptococcus neoformans	29.86	4.00e-45	173.00
IUUC-Cme-027239	Cyanidioschyzon merolae	39.27	2.00e-39	154.00
IUUC-Dre-028172	Danio rerio	38.30	2.00e-56	211.00
IUUC-Dno-029472	Dasypus novemcinctus	42.01	1.00e-42	164.00
IUUC-Dor-031134	Dipodomys ordii	33.62	5.00e-32	129.00
IUUC-Dse-031535	Dothistroma septosporum	29.72	3.00e-50	190.00
IUUC-Dme-032020	Drosophila melanogaster	39.88	2.00e-63	233.00
IUUC-Eca-033700	Equus caballus	38.73	3.00e-46	176.00
IUUC-Eeu-035010	Erinaceus europaeus	37.86	1.00e-43	167.00
IUUC-Fca-036309	Felis catus	34.10	2.00e-40	157.00
IUUC-Fal-037243	Ficedula albicollis	51.81	6.00e-37	145.00
IUUC-Fox-038058	Fusarium oxysporum	35.60	1.00e-52	199.00
IUUC-Fso-038459	Fusarium solani	33.89	6.00e-51	192.00
IUUC-Gmo-039375	Gadus morhua	38.12	2.00e-46	177.00
IUUC-Ggr-040002	Gaeumannomyces graminis	35.71	6.00e-44	169.00
IUUC-Gga-040294	Gallus gallus	52.66	1.00e-37	147.00
IUUC-Gac-042499	Gasterosteus aculeatus	37.69	6.00e-42	162.00
IUUC-Gma-043543	Glycine max	40.12	1.00e-61	228.00
IUUC-Ggo-045181	Gorilla gorilla	39.31	1.00e-46	178.00
IUUC-Hsa-046528	Homo sapiens	39.31	1.00e-46	178.00
IUUC-Hvu-047341	Hordeum vulgare	54.75	2.00e-48	182.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	39.48	7.00e-47	178.00
IUUC-Kpa-049353	Komagataella pastoris	40.52	4.00e-71	259.00
IUUC-Lch-049763	Latimeria chalumnae	37.90	8.00e-47	178.00
IUUC-Lpe-051500	Leersia perrieri	40.00	8.00e-56	208.00
IUUC-Loc-052021	Lepisosteus oculatus	37.98	3.00e-44	170.00
IUUC-Lma-053331	Leptosphaeria maculans	36.52	1.00e-62	233.00
IUUC-Laf-054558	Loxodonta africana	38.33	5.00e-46	176.00
IUUC-Mcc-055374	Macaca mulatta	38.26	1.00e-46	178.00
IUUC-Meu-056042	Macropus eugenii	55.09	3.00e-40	156.00
IUUC-Mor-057187	Magnaporthe oryzae	34.04	4.00e-50	190.00
IUUC-Mtr-058072	Medicago truncatula	39.36	6.00e-57	212.00
IUUC-Mla-059108	Melampsora laricipopulina	30.30	2.00e-42	164.00
IUUC-Mvi-060495	Microbotryum violaceum	33.06	2.00e-47	181.00
IUUC-Mmr-060902	Microcebus murinus	39.48	3.00e-47	179.00
IUUC-Mdo-062510	Monodelphis domestica	48.09	4.00e-45	173.00
IUUC-Mmu-063575	Mus musculus	39.18	1.00e-46	177.00
IUUC-Mac-065322	Musa acuminata	39.18	1.00e-58	218.00
IUUC-Mpu-065925	Mustela putorius furo	38.73	1.00e-46	178.00
IUUC-Mlu-067755	Myotis lucifugus	40.06	1.00e-47	181.00
IUUC-Nfi-068327	Neosartorya fischeri	32.57	1.00e-50	192.00
IUUC-Ncr-068845	Neurospora crassa	31.58	3.00e-40	157.00
IUUC-Nle-069406	Nomascus leucogenys	39.31	1.00e-45	174.00
IUUC-Opr-070416	Ochotona princeps	50.93	4.00e-29	120.00
IUUC-Ont-071936	Oreochromis niloticus	37.06	8.00e-43	165.00
IUUC-Oan-073452	Ornithorhynchus anatinus	55.97	2.00e-29	119.00
IUUC-Ocu-074791	Oryctolagus cuniculus	39.36	5.00e-48	182.00
IUUC-Oba-075636	Oryza barthii	41.16	3.00e-59	219.00
IUUC-Obr-076742	Oryza brachyantha	42.23	5.00e-53	199.00
IUUC-Ogl-077766	Oryza glaberrima	41.16	3.00e-59	219.00
IUUC-Ogu-079039	Oryza glumaepatula	40.87	3.00e-58	216.00
IUUC-Oin-079315	Oryza indica	42.57	3.00e-53	200.00
IUUC-Olo-080669	Oryza longistaminata	38.58	7.00e-54	202.00
IUUC-Ome-081490	Oryza meridionalis	41.16	2.00e-59	220.00
IUUC-Oni-082572	Oryza nivara	41.16	3.00e-59	219.00
IUUC-Opu-083732	Oryza punctata	40.75	1.00e-58	218.00
IUUC-Oru-084763	Oryza rufipogon	41.16	3.00e-59	219.00
IUUC-Osa-085372	Oryza sativa	41.16	3.00e-59	219.00
IUUC-Ola-087379	Oryzias latipes	37.65	1.00e-43	168.00
IUUC-Olu-087801	Ostreococcus lucimarinus	33.24	7.00e-39	152.00
IUUC-Oga-089076	Otolemur garnettii	38.92	5.00e-47	179.00
IUUC-Oar-090022	Ovis aries	38.75	2.00e-48	184.00
IUUC-Ptr-090809	Pan troglodytes	39.31	1.00e-46	178.00
IUUC-Pan-091685	Papio anubis	38.75	7.00e-47	179.00
IUUC-Psi-093046	Pelodiscus sinensis	37.97	1.00e-44	171.00
IUUC-Pma-094181	Petromyzon marinus	40.18	1.00e-58	217.00
IUUC-Pno-094882	Phaeosphaeria nodorum	34.22	3.00e-56	210.00
IUUC-Ppa-095172	Physcomitrella patens	37.78	1.00e-54	204.00
IUUC-Pfo-096396	Poecilia formosa	38.82	2.00e-44	170.00
IUUC-Pab-098427	Pongo abelii	39.24	2.00e-47	180.00
IUUC-Pop-100016	Populus trichocarpa	39.42	1.00e-59	221.00
IUUC-Pca-101048	Procavia capensis	39.77	1.00e-46	177.00
IUUC-Ppe-102050	Prunus persica	40.29	2.00e-61	226.00
IUUC-Pva-103117	Pteropus vampyrus	39.35	1.00e-46	177.00
IUUC-Pgr-103307	Puccinia graminis	33.94	5.00e-47	179.00
IUUC-Ptt-103938	Puccinia triticina	36.21	1.00e-38	151.00
IUUC-Pte-104315	Pyrenophora teres	34.07	1.00e-61	228.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	34.16	5.00e-61	226.00
IUUC-Rno-105523	Rattus norvegicus	39.18	1.00e-46	178.00
IUUC-Sce-106297	Saccharomyces cerevisiae	39.02	6.00e-61	225.00
IUUC-Sha-106981	Sarcophilus harrisii	56.29	2.00e-40	157.00
IUUC-Spo-108214	Schizosaccharomyces pombe	67.87	0.00e+00	810.00
IUUC-Smo-109034	Selaginella moellendorffii	37.68	3.00e-51	193.00
IUUC-Sit-110663	Setaria italica	39.77	7.00e-58	215.00
IUUC-Sly-110898	Solanum lycopersicum	39.18	1.00e-53	201.00
IUUC-Stu-112647	Solanum tuberosum	48.21	7.00e-51	191.00
IUUC-Sbi-114288	Sorghum bicolor	40.12	6.00e-58	215.00
IUUC-Sre-115065	Sporisorium reilianum	35.57	9.00e-60	222.00
IUUC-Ssc-115960	Sus scrofa	36.36	1.00e-48	184.00
IUUC-Tru-118382	Takifugu rubripes	39.52	5.00e-55	206.00
IUUC-Tsy-119585	Tarsius syrichta	36.63	5.00e-40	155.00
IUUC-Tni-120133	Tetraodon nigroviridis	37.39	2.00e-47	180.00
IUUC-Tca-121167	Theobroma cacao	40.41	4.00e-55	206.00
IUUC-Tre-122119	Trichoderma reesei	30.44	1.00e-42	165.00
IUUC-Tvi-122407	Trichoderma virens	33.25	7.00e-47	179.00
IUUC-Tae-124500	Triticum aestivum	40.47	9.00e-56	208.00
IUUC-Tur-126682	Triticum urartu	41.39	6.00e-50	188.00
IUUC-Tme-127095	Tuber melanosporum	38.92	5.00e-68	249.00
IUUC-Tbe-128004	Tupaia belangeri	39.77	2.00e-47	180.00
IUUC-Ttr-129284	Tursiops truncatus	39.04	1.00e-43	167.00
IUUC-Uma-129527	Ustilago maydis	38.18	1.00e-59	221.00
IUUC-Vda-129854	Verticillium dahliae	32.36	2.00e-46	178.00
IUUC-Vpa-130681	Vicugna pacos	61.90	7.00e-24	102.00
IUUC-Vvi-131004	Vitis vinifera	40.74	3.00e-60	223.00
IUUC-Xtr-131928	Xenopus tropicalis	35.59	6.00e-44	169.00
IUUC-Xma-134290	Xiphophorus maculatus	38.71	2.00e-43	167.00
IUUC-Yli-134364	Yarrowia lipolytica	44.08	8.00e-77	278.00
IUUC-Zma-135658	Zea mays	39.53	6.00e-56	209.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence