iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069605

Ensembl Protein ID

ENSNLEP00000011433.2

UniProt Accession

G1RDY3; G1RDY3_NOMLE

Genbank Protein ID

ENSNLEP00000011433

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01080612

Gene Name

UBE4B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000009386.2	ENSNLET00000011994.2	ENSNLEP00000011433.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.20e-22	78.0	1221	1292

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
            p+ef++p++ +lM+dPv lpsG  +drs I ++l ++ + +P++rq+lte++l P  +l++ iqaw+ e+++
   Q: 1221 APDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPT-DPFNRQTLTESMLEPVPELKEQIQAWMREKQN 1292
           79**********************************9998.***************************99986 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MEELSADEIR RRRLARLAGG QTSQPTTPLT SPQRENPPGP PIAASAPGPS QSLGLNVHNM 60
TPATSPIGAS GVAHRSQSSE GVSSLSSSPS NSLETQSQSL SRSQSMDIDG VSCEKSMSQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGACCAGTT CCCGCCAGGG GCAAAGGGTA GGAAGAGAGC AGGATCTGCT GTAGGAACGC 60
AGCTACCGCG CCACTATCAC GAAGACACAG CAGGCTCGGA GCACGAGACG AACTGGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008626--P:granzyme-mediated apoptotic signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000585	Aegilops tauschii	32.58	3.00e-94	339.00
IUUC-Aml-002396	Ailuropoda melanoleuca	97.76	0.00e+00	1696.00
IUUC-Atr-002479	Amborella trichopoda	32.02	3.00e-98	352.00
IUUC-Apl-003747	Anas platyrhynchos	93.15	0.00e+00	1639.00
IUUC-Aca-004866	Anolis carolinensis	92.81	0.00e+00	1620.00
IUUC-Aly-006300	Arabidopsis lyrata	30.33	4.00e-87	316.00
IUUC-Ath-006962	Arabidopsis thaliana	30.34	1.00e-84	307.00
IUUC-Ago-007880	Ashbya gossypii	29.06	4.00e-75	276.00
IUUC-Acl-008289	Aspergillus clavatus	30.08	4.00e-95	343.00
IUUC-Afl-008711	Aspergillus flavus	30.16	2.00e-99	357.00
IUUC-Afu-008766	Aspergillus fumigatus	30.54	4.00e-100	359.00
IUUC-Ani-009126	Aspergillus nidulans	30.19	8.00e-98	352.00
IUUC-Ang-009837	Aspergillus niger	30.00	6.00e-95	342.00
IUUC-Aor-009919	Aspergillus oryzae	29.72	1.00e-95	344.00
IUUC-Ate-010300	Aspergillus terreus	31.18	5.00e-102	366.00
IUUC-Ame-011355	Astyanax mexicanus	83.82	0.00e+00	1533.00
IUUC-Bgr-011995	Blumeria graminis	30.37	9.00e-98	351.00
IUUC-Bta-013056	Bos taurus	97.99	0.00e+00	1701.00
IUUC-Bci-013605	Botrytis cinerea	28.49	4.00e-84	306.00
IUUC-Bdi-015032	Brachypodium distachyon	29.46	2.00e-88	320.00
IUUC-Bol-016124	Brassica oleracea	30.75	3.00e-93	337.00
IUUC-Bra-016633	Brassica rapa	30.63	1.00e-93	338.00
IUUC-Cel-018606	Caenorhabditis elegans	30.63	5.00e-98	352.00
IUUC-Cja-018872	Callithrix jacchus	91.59	0.00e+00	2088.00
IUUC-Cfa-020045	Canis familiaris	97.65	0.00e+00	1694.00
IUUC-Cpo-022309	Cavia porcellus	97.09	0.00e+00	1689.00
IUUC-Cre-022726	Chlamydomonas reinhardtii	29.79	1.00e-47	184.00
IUUC-Csa-024003	Chlorocebus sabaeus	96.87	0.00e+00	1074.00
IUUC-Cho-025092	Choloepus hoffmanni	98.03	0.00e+00	702.00
IUUC-Cin-025533	Ciona intestinalis	47.28	0.00e+00	810.00
IUUC-Csv-026081	Ciona savignyi	63.98	2.00e-60	224.00
IUUC-Cgl-026710	Colletotrichum gloeosporioides	31.29	4.00e-100	359.00
IUUC-Cne-027098	Cryptococcus neoformans	29.36	2.00e-100	360.00
IUUC-Cme-027352	Cyanidioschyzon merolae	32.07	4.00e-85	310.00
IUUC-Dre-027979	Danio rerio	83.46	0.00e+00	1481.00
IUUC-Dno-029282	Dasypus novemcinctus	97.87	0.00e+00	1697.00
IUUC-Dor-030904	Dipodomys ordii	77.68	0.00e+00	780.00
IUUC-Dse-031393	Dothistroma septosporum	29.54	7.00e-94	338.00
IUUC-Dme-031666	Drosophila melanogaster	42.24	0.00e+00	679.00
IUUC-Ete-032519	Echinops telfairi	99.08	2.00e-180	626.00
IUUC-Eca-033778	Equus caballus	97.32	0.00e+00	1685.00
IUUC-Eeu-035315	Erinaceus europaeus	90.02	0.00e+00	903.00
IUUC-Fca-035658	Felis catus	97.43	0.00e+00	1686.00
IUUC-Fal-037638	Ficedula albicollis	92.57	0.00e+00	1628.00
IUUC-Fox-037909	Fusarium oxysporum	29.42	7.00e-93	335.00
IUUC-Fso-038406	Fusarium solani	30.14	3.00e-91	330.00
IUUC-Gmo-039379	Gadus morhua	83.20	0.00e+00	1477.00
IUUC-Ggr-039851	Gaeumannomyces graminis	31.76	1.00e-100	361.00
IUUC-Gga-041136	Gallus gallus	93.24	0.00e+00	1642.00
IUUC-Gac-041910	Gasterosteus aculeatus	83.39	0.00e+00	1485.00
IUUC-Ggo-045354	Gorilla gorilla	93.10	0.00e+00	1599.00
IUUC-Hsa-046880	Homo sapiens	98.56	0.00e+00	1755.00
IUUC-Hvu-047157	Hordeum vulgare	32.62	5.00e-89	322.00
IUUC-Itr-048213	Ictidomys tridecemlineatus	98.80	0.00e+00	641.00
IUUC-Kpa-049211	Komagataella pastoris	27.86	2.00e-74	273.00
IUUC-Lch-050534	Latimeria chalumnae	86.88	0.00e+00	1568.00
IUUC-Lpe-051022	Leersia perrieri	30.57	5.00e-89	322.00
IUUC-Loc-052622	Lepisosteus oculatus	85.44	0.00e+00	1506.00
IUUC-Lma-053241	Leptosphaeria maculans	30.07	2.00e-92	334.00
IUUC-Laf-053646	Loxodonta africana	96.71	0.00e+00	1721.00
IUUC-Mcc-055588	Macaca mulatta	98.66	0.00e+00	1714.00
IUUC-Meu-055999	Macropus eugenii	78.40	0.00e+00	1285.00
IUUC-Mor-057064	Magnaporthe oryzae	30.68	3.00e-100	359.00
IUUC-Mpo-057452	Magnaporthe poae	31.87	7.00e-103	369.00
IUUC-Mtr-058016	Medicago truncatula	29.72	4.00e-97	349.00
IUUC-Mla-058887	Melampsora laricipopulina	33.05	3.00e-106	379.00
IUUC-Mga-059497	Meleagris gallopavo	93.02	0.00e+00	1636.00
IUUC-Mvi-060343	Microbotryum violaceum	34.25	9.00e-108	385.00
IUUC-Mmr-061173	Microcebus murinus	88.93	0.00e+00	1472.00
IUUC-Mdo-062102	Monodelphis domestica	94.38	0.00e+00	1642.00
IUUC-Mmu-063223	Mus musculus	96.65	0.00e+00	1684.00
IUUC-Mac-065531	Musa acuminata	30.91	5.00e-93	335.00
IUUC-Mpu-066624	Mustela putorius furo	65.57	0.00e+00	1014.00
IUUC-Mlu-068018	Myotis lucifugus	96.76	0.00e+00	1680.00
IUUC-Nfi-068590	Neosartorya fischeri	30.97	4.00e-101	362.00
IUUC-Ncr-068901	Neurospora crassa	31.04	5.00e-97	349.00
IUUC-Opr-071011	Ochotona princeps	83.11	0.00e+00	826.00
IUUC-Ont-072304	Oreochromis niloticus	82.80	0.00e+00	1460.00
IUUC-Oan-073410	Ornithorhynchus anatinus	95.80	0.00e+00	1055.00
IUUC-Ocu-074910	Oryctolagus cuniculus	96.96	0.00e+00	1674.00
IUUC-Oba-075073	Oryza barthii	30.75	1.00e-94	341.00
IUUC-Obr-076452	Oryza brachyantha	30.70	3.00e-93	336.00
IUUC-Ogl-077141	Oryza glaberrima	30.75	1.00e-94	341.00
IUUC-Ogu-078116	Oryza glumaepatula	30.87	7.00e-95	342.00
IUUC-Oin-079066	Oryza indica	30.87	4.00e-95	343.00
IUUC-Olo-080253	Oryza longistaminata	28.86	1.00e-81	297.00
IUUC-Oni-082019	Oryza nivara	30.99	5.00e-95	342.00
IUUC-Opu-083558	Oryza punctata	30.79	1.00e-95	344.00
IUUC-Oru-085002	Oryza rufipogon	30.75	1.00e-94	341.00
IUUC-Osa-085980	Oryza sativa	30.87	4.00e-95	343.00
IUUC-Ola-086323	Oryzias latipes	80.13	0.00e+00	1409.00
IUUC-Olu-087901	Ostreococcus lucimarinus	31.06	2.00e-93	337.00
IUUC-Oga-087969	Otolemur garnettii	93.52	0.00e+00	1597.00
IUUC-Oar-090020	Ovis aries	94.14	0.00e+00	1634.00
IUUC-Ptr-091589	Pan troglodytes	98.56	0.00e+00	1756.00
IUUC-Pan-091718	Papio anubis	97.26	0.00e+00	828.00
IUUC-Psi-093013	Pelodiscus sinensis	93.17	0.00e+00	1653.00
IUUC-Pma-094627	Petromyzon marinus	74.55	0.00e+00	627.00
IUUC-Pno-094840	Phaeosphaeria nodorum	29.93	6.00e-99	355.00
IUUC-Ppa-095989	Physcomitrella patens	29.41	5.00e-97	349.00
IUUC-Pfo-096436	Poecilia formosa	83.90	0.00e+00	1513.00
IUUC-Pab-098275	Pongo abelii	83.96	0.00e+00	1394.00
IUUC-Pop-098797	Populus trichocarpa	29.91	6.00e-98	352.00
IUUC-Pca-100478	Procavia capensis	71.10	0.00e+00	640.00
IUUC-Ppe-101230	Prunus persica	30.75	4.00e-100	359.00
IUUC-Pva-102459	Pteropus vampyrus	92.62	0.00e+00	1583.00
IUUC-Pgr-103485	Puccinia graminis	32.69	2.00e-105	377.00
IUUC-Ptt-104001	Puccinia triticina	42.74	2.00e-45	177.00
IUUC-Pte-104084	Pyrenophora teres	32.00	5.00e-106	379.00
IUUC-Pyt-104484	Pyrenophora triticirepentis	31.85	2.00e-105	377.00
IUUC-Rno-105719	Rattus norvegicus	96.76	0.00e+00	1684.00
IUUC-Sce-106135	Saccharomyces cerevisiae	36.49	3.00e-71	263.00
IUUC-Sha-106760	Sarcophilus harrisii	94.37	0.00e+00	1638.00
IUUC-Sja-107698	Schizosaccharomyces japonicus	32.78	4.00e-113	402.00
IUUC-Spo-108076	Schizosaccharomyces pombe	32.97	4.00e-105	375.00
IUUC-Ssl-108624	Sclerotinia sclerotiorum	29.30	2.00e-95	344.00
IUUC-Smo-108769	Selaginella moellendorffii	28.92	1.00e-88	321.00
IUUC-Sit-109949	Setaria italica	30.89	9.00e-91	328.00
IUUC-Sly-110973	Solanum lycopersicum	31.09	1.00e-83	304.00
IUUC-Stu-112372	Solanum tuberosum	29.77	2.00e-99	357.00
IUUC-Sar-113469	Sorex araneus	87.83	0.00e+00	976.00
IUUC-Sbi-113828	Sorghum bicolor	31.04	1.00e-93	337.00
IUUC-Sre-114967	Sporisorium reilianum	32.30	9.00e-101	361.00
IUUC-Ssc-115655	Sus scrofa	95.84	0.00e+00	1070.00
IUUC-Tgu-117290	Taeniopygia guttata	92.70	0.00e+00	1591.00
IUUC-Tru-118193	Takifugu rubripes	83.28	0.00e+00	1497.00
IUUC-Tsy-118926	Tarsius syrichta	97.56	0.00e+00	1709.00
IUUC-Tni-120862	Tetraodon nigroviridis	84.44	0.00e+00	1472.00
IUUC-Tca-121096	Theobroma cacao	31.40	2.00e-99	357.00
IUUC-Tre-122104	Trichoderma reesei	29.77	7.00e-94	339.00
IUUC-Tvi-122345	Trichoderma virens	30.54	2.00e-97	351.00
IUUC-Tae-124839	Triticum aestivum	32.58	2.00e-94	340.00
IUUC-Tur-126056	Triticum urartu	32.58	2.00e-94	340.00
IUUC-Tme-127074	Tuber melanosporum	32.65	2.00e-94	340.00
IUUC-Tbe-127533	Tupaia belangeri	93.00	0.00e+00	1615.00
IUUC-Ttr-128757	Tursiops truncatus	93.78	0.00e+00	1665.00
IUUC-Uma-129550	Ustilago maydis	32.08	4.00e-101	362.00
IUUC-Vda-129901	Verticillium dahliae	30.18	2.00e-95	344.00
IUUC-Vpa-130636	Vicugna pacos	95.50	0.00e+00	998.00
IUUC-Vvi-130891	Vitis vinifera	30.86	3.00e-97	350.00
IUUC-Xtr-132364	Xenopus tropicalis	86.50	0.00e+00	1540.00
IUUC-Xma-133772	Xiphophorus maculatus	83.79	0.00e+00	1509.00
IUUC-Yli-134506	Yarrowia lipolytica	30.68	2.00e-80	294.00
IUUC-Zma-135695	Zea mays	30.46	1.00e-87	317.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence