iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068815

Ensembl Protein ID

EAA36314

UniProt Accession

Q7SH87; Q7SH87_NEUCR

Genbank Protein ID

EAA36314.1

Protein Name

Ubiquitin C-terminal hydrolase

Genbank Nucleotide ID

CM002236

Gene Name

NCU01919

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU01919	EAA36314	EAA36314

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-56	191.6	110	537
ULD/UDP/UBQ/UBQ_Other	1.60e-09	36.5	10	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.......gyeqqDaqEf 95
           Gl+N+gNtCY+NS+LQ+L +ipel ++l++ +k + +  +        +++l++l   + +++++ + p ++l+al+ + ++f        gy+qqDa+E 
   Q: 110  GLQNFGNTCYLNSTLQVLRSIPELNDALKS-YKGEQSMLD-------PTSQLRNLYDMM-SKTQEGIPPLAFLNALRVAFPQFAererdghGYAQQDAEEA 201
           9*****************************.666655554.......489999999877.9999*******************99**************** PP
   S: 96   laflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs......sreepfldlslpvpgkeetkkeslqdc 190
           ++++l ql+++lk                      +e +  +  s+i++ ++ +l+s + c e + +       +++e  l+l++++ g+++     l+d 
   Q: 202  WSQILTQLKQKLK---------------------ISEGDAARDASFIDKYMGLELTSVLECDEPGAKEageepkTSKERLLKLNCHIDGQTN----HLRDG 277
           ************2.....................245678999******************6655443111113667777888888888886....57777 PP
   S: 191  LesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts........................ 267
           + +    e+le+    ++e  +++ + +k+ ++++lP++L++h++Rf +++e +++ ki +kv+fp eLd+ +fct+                        
   Q: 278  IVNGL-VEKLEK----KSEVLDREATYTKRSQISRLPKYLTVHFMRFFWKREVQKKAKIMRKVTFPHELDVVEFCTDelrkalipvrdkvrevrkeehdie 373
           74433.466774....78899999999**************************************************999999999999999999999999 PP
   S: 268  .............................................................................peekqkekkkYeLiavvvHsG.sl 290
                                                                                        ++e+ +++  YeL +v+ H+G s+
   Q: 374  rarkrrkmnpidgenaqgsqpstskdkkkdekkpaggdvemtteetfktdaefeaekeaevlaakkelytlinqdllKDEGANQSGLYELRGVITHQGaSA 474
           999999999999999999988888777777777777777776666666666666666666666666666666666664444445***************** PP
   S: 291  ssGHYvayvkn.............ekgkWllfdDskVtevkeeevleetg....staYvlfYk 336
           +sGHY+ayvk+             e+gkW+ f+D+kV+ev+ e++    g    ++a +l+Y+
   Q: 475  DSGHYTAYVKKtgikdpvtgkvgeEDGKWWWFNDDKVSEVEAEKITALAGggesHSALILLYR 537
           ***********99999999999988999******************98889***********8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 8    ldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekk 73
            +g+ +++ v+ s+t  ++K ++++++g+ p++q+ ++kG  L+dd + + +glk+g+ i+++ + 
   Q: 10   HQGKKYDVDVDTSATGEVFKYQLYSLTGVEPDRQKVLLKGSQLKDDTDMSKVGLKPGQMIMMMGTP 75
           467899999*****************************************************9875 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MSTINVVVKH QGKKYDVDVD TSATGEVFKY QLYSLTGVEP DRQKVLLKGS QLKDDTDMSK 60
VGLKPGQMIM MMGTPGEGGG AIVRPTEKVK FVEDMTEAEA AQQAGATPAG LQNFGNTCYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCCCGCG CTGTCCCGTC TTCTGTCACC TTCGACAACT TTCAAATCAC CAAGCTTGTG 60
GAAGTTGCCT CCGGATCTGC CTTCCAATAC ATCAGAATCA AAGTCGCCGA CGAGGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005838--C:proteasome regulatory particle
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ncr:NCU01919

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	28.07	1.00e-28	119.00
IUUC-Aml-002053	Ailuropoda melanoleuca	36.20	3.00e-81	293.00
IUUC-Atr-002725	Amborella trichopoda	36.78	3.00e-80	290.00
IUUC-Apl-004031	Anas platyrhynchos	35.50	3.00e-79	287.00
IUUC-Aca-004361	Anolis carolinensis	36.59	5.00e-87	313.00
IUUC-Aly-006176	Arabidopsis lyrata	38.01	1.00e-86	311.00
IUUC-Ath-007658	Arabidopsis thaliana	38.03	6.00e-88	316.00
IUUC-Ago-007796	Ashbya gossypii	36.10	2.00e-82	297.00
IUUC-Acl-008258	Aspergillus clavatus	59.59	0.00e+00	636.00
IUUC-Afl-008732	Aspergillus flavus	61.72	0.00e+00	669.00
IUUC-Afu-008755	Aspergillus fumigatus	60.55	1.00e-180	624.00
IUUC-Ani-009148	Aspergillus nidulans	60.83	0.00e+00	651.00
IUUC-Ang-009878	Aspergillus niger	61.14	0.00e+00	656.00
IUUC-Aor-010239	Aspergillus oryzae	61.72	0.00e+00	669.00
IUUC-Ate-010243	Aspergillus terreus	62.20	0.00e+00	654.00
IUUC-Ame-011327	Astyanax mexicanus	32.00	5.00e-23	100.00
IUUC-Bgr-012231	Blumeria graminis	61.81	0.00e+00	678.00
IUUC-Bta-012553	Bos taurus	35.66	8.00e-83	298.00
IUUC-Bci-013606	Botrytis cinerea	62.00	0.00e+00	660.00
IUUC-Bdi-014567	Brachypodium distachyon	44.02	1.00e-73	268.00
IUUC-Bol-015565	Brassica oleracea	38.12	9.00e-90	322.00
IUUC-Bra-017297	Brassica rapa	38.05	2.00e-88	317.00
IUUC-Cel-018140	Caenorhabditis elegans	33.25	1.00e-48	186.00
IUUC-Cja-019516	Callithrix jacchus	36.20	2.00e-84	304.00
IUUC-Cfa-020808	Canis familiaris	36.38	4.00e-82	296.00
IUUC-Cpo-021688	Cavia porcellus	35.99	3.00e-82	297.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	32.85	1.00e-59	222.00
IUUC-Csa-023429	Chlorocebus sabaeus	35.84	2.00e-81	294.00
IUUC-Cho-024347	Choloepus hoffmanni	36.20	3.00e-81	293.00
IUUC-Cin-025198	Ciona intestinalis	38.50	1.00e-57	215.00
IUUC-Csv-026007	Ciona savignyi	36.58	1.00e-58	219.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	67.84	0.00e+00	665.00
IUUC-Cne-026963	Cryptococcus neoformans	37.43	1.00e-83	301.00
IUUC-Cme-027240	Cyanidioschyzon merolae	35.42	7.00e-49	186.00
IUUC-Dre-027647	Danio rerio	37.79	3.00e-88	317.00
IUUC-Dno-029967	Dasypus novemcinctus	36.38	1.00e-80	291.00
IUUC-Dor-030886	Dipodomys ordii	31.61	3.00e-57	214.00
IUUC-Dse-031466	Dothistroma septosporum	50.59	5.00e-144	502.00
IUUC-Dme-032079	Drosophila melanogaster	35.97	1.00e-61	228.00
IUUC-Ete-032351	Echinops telfairi	34.38	1.00e-74	271.00
IUUC-Eca-033461	Equus caballus	35.66	6.00e-85	306.00
IUUC-Eeu-035220	Erinaceus europaeus	32.75	1.00e-39	155.00
IUUC-Fca-036210	Felis catus	36.38	2.00e-82	297.00
IUUC-Fal-037528	Ficedula albicollis	35.79	3.00e-79	287.00
IUUC-Fox-037805	Fusarium oxysporum	66.61	0.00e+00	681.00
IUUC-Fso-038177	Fusarium solani	68.64	0.00e+00	690.00
IUUC-Gmo-038953	Gadus morhua	39.55	7.00e-70	256.00
IUUC-Ggr-039972	Gaeumannomyces graminis	66.19	0.00e+00	672.00
IUUC-Gga-040462	Gallus gallus	36.07	4.00e-80	290.00
IUUC-Gac-041312	Gasterosteus aculeatus	44.71	7.00e-16	76.60
IUUC-Gma-043255	Glycine max	38.72	1.00e-89	321.00
IUUC-Ggo-045458	Gorilla gorilla	33.57	1.00e-48	185.00
IUUC-Hsa-045706	Homo sapiens	35.84	2.00e-81	294.00
IUUC-Hvu-047821	Hordeum vulgare	42.86	1.00e-41	161.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	36.20	2.00e-84	304.00
IUUC-Lch-050464	Latimeria chalumnae	35.92	2.00e-76	277.00
IUUC-Lpe-051419	Leersia perrieri	40.95	1.00e-70	258.00
IUUC-Loc-052732	Lepisosteus oculatus	41.13	1.00e-72	265.00
IUUC-Lma-053177	Leptosphaeria maculans	60.98	0.00e+00	633.00
IUUC-Laf-053822	Loxodonta africana	36.20	2.00e-80	291.00
IUUC-Mcc-055893	Macaca mulatta	35.84	2.00e-81	294.00
IUUC-Meu-056307	Macropus eugenii	38.22	1.00e-63	235.00
IUUC-Mor-057171	Magnaporthe oryzae	68.83	0.00e+00	719.00
IUUC-Mpo-057415	Magnaporthe poae	67.91	0.00e+00	686.00
IUUC-Mtr-057901	Medicago truncatula	38.07	4.00e-87	313.00
IUUC-Mla-058897	Melampsora laricipopulina	40.97	1.00e-98	352.00
IUUC-Mga-060016	Meleagris gallopavo	36.04	9.00e-79	285.00
IUUC-Mvi-060562	Microbotryum violaceum	46.74	3.00e-84	304.00
IUUC-Mmr-060624	Microcebus murinus	36.20	1.00e-87	314.00
IUUC-Mdo-061809	Monodelphis domestica	36.43	8.00e-83	299.00
IUUC-Mmu-063869	Mus musculus	35.66	2.00e-83	301.00
IUUC-Mac-064876	Musa acuminata	36.08	2.00e-74	271.00
IUUC-Mpu-066480	Mustela putorius furo	36.20	1.00e-81	295.00
IUUC-Mlu-067866	Myotis lucifugus	35.84	1.00e-82	298.00
IUUC-Nfi-068393	Neosartorya fischeri	60.55	0.00e+00	639.00
IUUC-Nle-070121	Nomascus leucogenys	41.15	4.00e-46	176.00
IUUC-Opr-070712	Ochotona princeps	31.49	4.00e-42	164.00
IUUC-Ont-071544	Oreochromis niloticus	42.23	2.00e-71	261.00
IUUC-Oan-073635	Ornithorhynchus anatinus	33.61	3.00e-60	223.00
IUUC-Ocu-074926	Oryctolagus cuniculus	35.55	4.00e-80	290.00
IUUC-Oba-075633	Oryza barthii	42.93	2.00e-69	254.00
IUUC-Obr-076423	Oryza brachyantha	44.05	2.00e-73	267.00
IUUC-Ogl-077913	Oryza glaberrima	44.02	3.00e-74	270.00
IUUC-Ogu-078435	Oryza glumaepatula	42.93	2.00e-69	254.00
IUUC-Oin-080072	Oryza indica	42.74	1.00e-69	254.00
IUUC-Olo-080535	Oryza longistaminata	33.58	8.00e-67	245.00
IUUC-Ome-081309	Oryza meridionalis	42.93	2.00e-69	254.00
IUUC-Oni-083113	Oryza nivara	42.93	2.00e-69	254.00
IUUC-Opu-083168	Oryza punctata	41.30	3.00e-63	234.00
IUUC-Oru-084253	Oryza rufipogon	42.93	2.00e-69	254.00
IUUC-Osa-085554	Oryza sativa	44.02	3.00e-74	270.00
IUUC-Ola-086998	Oryzias latipes	42.27	5.00e-71	259.00
IUUC-Olu-087818	Ostreococcus lucimarinus	34.18	2.00e-49	187.00
IUUC-Oga-088571	Otolemur garnettii	36.45	2.00e-82	298.00
IUUC-Oar-089526	Ovis aries	35.80	4.00e-82	296.00
IUUC-Ptr-091433	Pan troglodytes	35.84	2.00e-81	294.00
IUUC-Pan-091966	Papio anubis	35.84	2.00e-81	294.00
IUUC-Psi-093458	Pelodiscus sinensis	36.21	4.00e-82	296.00
IUUC-Pma-094343	Petromyzon marinus	39.60	4.00e-48	182.00
IUUC-Pno-095109	Phaeosphaeria nodorum	59.72	0.00e+00	634.00
IUUC-Ppa-095756	Physcomitrella patens	38.32	3.00e-93	333.00
IUUC-Pfo-096514	Poecilia formosa	41.71	1.00e-70	258.00
IUUC-Pab-098477	Pongo abelii	32.27	9.00e-62	228.00
IUUC-Pop-099221	Populus trichocarpa	44.79	3.00e-71	260.00
IUUC-Pca-100791	Procavia capensis	30.84	2.00e-32	131.00
IUUC-Ppe-101812	Prunus persica	37.52	3.00e-82	297.00
IUUC-Pva-102462	Pteropus vampyrus	36.28	5.00e-53	199.00
IUUC-Pgr-103623	Puccinia graminis	46.51	5.00e-77	280.00
IUUC-Ptt-103767	Puccinia triticina	44.21	5.00e-71	259.00
IUUC-Pte-104109	Pyrenophora teres	61.70	0.00e+00	656.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	61.70	0.00e+00	646.00
IUUC-Rno-105351	Rattus norvegicus	35.48	3.00e-80	290.00
IUUC-Sce-106168	Saccharomyces cerevisiae	36.30	1.00e-81	295.00
IUUC-Sha-107491	Sarcophilus harrisii	35.96	1.00e-82	298.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	41.31	6.00e-104	369.00
IUUC-Spo-108174	Schizosaccharomyces pombe	41.87	6.00e-110	389.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	65.44	0.00e+00	657.00
IUUC-Smo-108805	Selaginella moellendorffii	37.98	1.00e-91	328.00
IUUC-Sit-110361	Setaria italica	44.17	8.00e-77	279.00
IUUC-Sly-110965	Solanum lycopersicum	37.59	3.00e-87	313.00
IUUC-Sar-113355	Sorex araneus	38.87	3.00e-54	204.00
IUUC-Sbi-114778	Sorghum bicolor	44.44	3.00e-74	270.00
IUUC-Sre-115011	Sporisorium reilianum	46.78	4.00e-84	303.00
IUUC-Ssc-116273	Sus scrofa	41.03	2.00e-66	244.00
IUUC-Tgu-117063	Taeniopygia guttata	35.54	3.00e-79	287.00
IUUC-Tru-118381	Takifugu rubripes	36.52	2.00e-82	298.00
IUUC-Tsy-119076	Tarsius syrichta	28.57	6.00e-26	110.00
IUUC-Tni-119941	Tetraodon nigroviridis	42.23	2.00e-74	271.00
IUUC-Tca-121246	Theobroma cacao	38.24	8.00e-86	308.00
IUUC-Tre-121969	Trichoderma reesei	63.91	0.00e+00	631.00
IUUC-Tvi-122543	Trichoderma virens	66.19	0.00e+00	671.00
IUUC-Tae-125484	Triticum aestivum	36.83	2.00e-77	280.00
IUUC-Tur-126128	Triticum urartu	37.98	5.00e-22	97.10
IUUC-Tbe-128030	Tupaia belangeri	32.00	1.00e-62	231.00
IUUC-Ttr-128701	Tursiops truncatus	40.00	2.00e-50	191.00
IUUC-Uma-129657	Ustilago maydis	45.25	7.00e-84	302.00
IUUC-Vda-129723	Verticillium dahliae	63.81	0.00e+00	682.00
IUUC-Vpa-130284	Vicugna pacos	29.41	2.00e-26	112.00
IUUC-Vvi-131037	Vitis vinifera	38.28	9.00e-86	308.00
IUUC-Xtr-132235	Xenopus tropicalis	41.18	2.00e-74	271.00
IUUC-Xma-133840	Xiphophorus maculatus	41.45	3.00e-70	257.00
IUUC-Yli-134453	Yarrowia lipolytica	47.11	3.00e-114	403.00
IUUC-Zma-135791	Zea mays	36.38	1.00e-77	281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence