iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020862

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03002395

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000014230.4	ENSCAFT00000022589.4	ENSCAFP00000020974.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-43	144.8	230	269
UBD/Beta-Prp	9.40e-74	248.6	12	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+++v  +af +d t++vs+s D+++kvWD+ t +++++
   Q: 230  GHASWVLNVAFcPDdTHFVSSSSDKSVKVWDVGTRTCVHT 269
           8***********777*****************99999875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++    +++++ ++tgs d+ +kvw++ ++ l   +sl+gh+ +v +v++s++ +i +++s D++i++wdl++gk++ 
   Q: 12   EQAHDDAIWSVAWgtnkKENSETVVTGSLDDLVKVWKWCDERLdlQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLDNGKQIK 100
           567788888899998888999*******************999989******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   ++++l+fsp++++l++G+h+  ++++ +e+g++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 101  SIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd+ ++++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++++++
   Q: 277  VWGVKY-NGNGSKIVSVGDDQEIHVYDC 303
           ******.999****************97 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MTNQYSILFK QEQAHDDAIW SVAWGTNKKE NSETVVTGSL DDLVKVWKWC DERLDLQWSL 60
EGHQLGVVSV DISHTLPIAA SSSLDAHIRL WDLDNGKQIK SIDAGPVDAW TLAFSPDSQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCAACC AGGTAAGGCC TATGGGGACG TTCGGAAGAA TAACACTTGG TTCCTTTGGC 60
AGGTGGAAGC CCAGGATGTG GTCTGGGTAT GTAGTCAGGA AACTAGCATC TGCTCCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

KEGG

cfa:479068

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	34.23	8.00e-48	184.00
IUUC-Aml-002245	Ailuropoda melanoleuca	99.34	2.00e-168	584.00
IUUC-Atr-003142	Amborella trichopoda	51.55	3.00e-38	151.00
IUUC-Apl-003179	Anas platyrhynchos	90.49	5.00e-156	543.00
IUUC-Aca-004880	Anolis carolinensis	89.51	4.00e-158	550.00
IUUC-Aly-005956	Arabidopsis lyrata	37.82	1.00e-55	209.00
IUUC-Ath-007230	Arabidopsis thaliana	37.50	2.00e-51	196.00
IUUC-Acl-008297	Aspergillus clavatus	28.88	1.00e-24	107.00
IUUC-Ang-009702	Aspergillus niger	29.90	1.00e-29	123.00
IUUC-Ame-011511	Astyanax mexicanus	83.39	9.00e-149	519.00
IUUC-Bgr-012189	Blumeria graminis	30.47	1.00e-28	120.00
IUUC-Bta-012936	Bos taurus	98.03	6.00e-167	579.00
IUUC-Bdi-015020	Brachypodium distachyon	37.93	1.00e-47	183.00
IUUC-Bol-016345	Brassica oleracea	39.10	6.00e-57	214.00
IUUC-Bra-017323	Brassica rapa	39.10	5.00e-57	214.00
IUUC-Cja-019961	Callithrix jacchus	98.36	3.00e-167	580.00
IUUC-Cpo-021356	Cavia porcellus	98.34	2.00e-165	574.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	42.24	2.00e-58	218.00
IUUC-Csa-024067	Chlorocebus sabaeus	98.03	1.00e-166	578.00
IUUC-Cho-024421	Choloepus hoffmanni	82.83	2.00e-82	297.00
IUUC-Cin-025261	Ciona intestinalis	64.59	2.00e-116	411.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	28.62	2.00e-29	123.00
IUUC-Cne-026846	Cryptococcus neoformans	29.13	2.00e-24	106.00
IUUC-Dre-027706	Danio rerio	65.25	2.00e-109	388.00
IUUC-Dno-029084	Dasypus novemcinctus	98.05	3.00e-166	577.00
IUUC-Dor-030353	Dipodomys ordii	82.97	6.00e-123	433.00
IUUC-Dse-031348	Dothistroma septosporum	30.17	1.00e-25	110.00
IUUC-Dme-031836	Drosophila melanogaster	52.31	3.00e-87	315.00
IUUC-Ete-032261	Echinops telfairi	95.08	1.00e-160	558.00
IUUC-Eca-034231	Equus caballus	90.49	7.00e-152	529.00
IUUC-Eeu-034828	Erinaceus europaeus	97.94	8.00e-156	542.00
IUUC-Fca-036569	Felis catus	99.34	3.00e-169	587.00
IUUC-Fal-037469	Ficedula albicollis	93.11	8.00e-161	559.00
IUUC-Fox-038047	Fusarium oxysporum	33.33	8.00e-30	124.00
IUUC-Gmo-039579	Gadus morhua	83.93	2.00e-146	511.00
IUUC-Gga-040808	Gallus gallus	93.15	3.00e-153	534.00
IUUC-Gac-042100	Gasterosteus aculeatus	84.26	1.00e-147	515.00
IUUC-Gma-044408	Glycine max	41.67	1.00e-59	223.00
IUUC-Ggo-045227	Gorilla gorilla	98.36	3.00e-167	580.00
IUUC-Hsa-045839	Homo sapiens	98.36	3.00e-167	580.00
IUUC-Hvu-047591	Hordeum vulgare	38.29	5.00e-50	191.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	98.69	6.00e-168	582.00
IUUC-Lch-049549	Latimeria chalumnae	83.61	5.00e-147	513.00
IUUC-Lpe-050746	Leersia perrieri	38.91	1.00e-48	186.00
IUUC-Loc-052540	Lepisosteus oculatus	86.56	1.00e-148	518.00
IUUC-Lma-052992	Leptosphaeria maculans	28.14	3.00e-27	115.00
IUUC-Laf-053907	Loxodonta africana	98.69	6.00e-168	582.00
IUUC-Mcc-055828	Macaca mulatta	92.00	3.00e-163	567.00
IUUC-Meu-056075	Macropus eugenii	94.09	3.00e-134	470.00
IUUC-Mtr-057728	Medicago truncatula	40.71	1.00e-56	213.00
IUUC-Mga-059872	Meleagris gallopavo	92.79	1.00e-160	558.00
IUUC-Mvi-060564	Microbotryum violaceum	31.77	2.00e-29	122.00
IUUC-Mmr-060985	Microcebus murinus	98.29	4.00e-159	553.00
IUUC-Mdo-062758	Monodelphis domestica	90.13	8.00e-158	549.00
IUUC-Mmu-063580	Mus musculus	97.05	2.00e-165	574.00
IUUC-Mac-064880	Musa acuminata	40.51	4.00e-58	218.00
IUUC-Mpu-066577	Mustela putorius furo	98.69	8.00e-167	579.00
IUUC-Nle-069573	Nomascus leucogenys	98.36	3.00e-167	580.00
IUUC-Opr-070216	Ochotona princeps	98.34	2.00e-164	571.00
IUUC-Ont-071981	Oreochromis niloticus	84.92	1.00e-149	521.00
IUUC-Oan-073223	Ornithorhynchus anatinus	93.91	3.00e-107	380.00
IUUC-Ocu-074199	Oryctolagus cuniculus	85.25	1.00e-140	491.00
IUUC-Oba-075255	Oryza barthii	40.38	6.00e-42	164.00
IUUC-Obr-076168	Oryza brachyantha	47.20	2.00e-35	142.00
IUUC-Ogl-077777	Oryza glaberrima	38.71	4.00e-49	188.00
IUUC-Ogu-078780	Oryza glumaepatula	38.71	4.00e-49	188.00
IUUC-Oin-079228	Oryza indica	38.71	7.00e-52	197.00
IUUC-Olo-080617	Oryza longistaminata	45.77	3.00e-29	120.00
IUUC-Ome-081421	Oryza meridionalis	38.71	2.00e-48	186.00
IUUC-Oni-082997	Oryza nivara	38.71	7.00e-52	197.00
IUUC-Opu-083931	Oryza punctata	39.03	3.00e-49	188.00
IUUC-Oru-084645	Oryza rufipogon	38.71	4.00e-49	188.00
IUUC-Osa-085842	Oryza sativa	38.71	7.00e-52	197.00
IUUC-Ola-086696	Oryzias latipes	84.59	2.00e-145	508.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.91	2.00e-41	162.00
IUUC-Oga-088272	Otolemur garnettii	97.04	4.00e-164	570.00
IUUC-Oar-089416	Ovis aries	98.03	6.00e-167	579.00
IUUC-Ptr-090944	Pan troglodytes	98.36	3.00e-167	580.00
IUUC-Pan-091861	Papio anubis	98.36	3.00e-167	580.00
IUUC-Psi-093750	Pelodiscus sinensis	93.11	8.00e-161	559.00
IUUC-Pma-094608	Petromyzon marinus	79.35	8.00e-135	473.00
IUUC-Pno-094832	Phaeosphaeria nodorum	36.26	6.00e-26	111.00
IUUC-Ppa-095737	Physcomitrella patens	40.38	1.00e-56	213.00
IUUC-Pfo-096479	Poecilia formosa	85.57	1.00e-143	501.00
IUUC-Pab-098179	Pongo abelii	98.36	3.00e-167	580.00
IUUC-Pop-099532	Populus trichocarpa	41.26	1.00e-56	213.00
IUUC-Pca-100664	Procavia capensis	76.09	8.00e-105	373.00
IUUC-Ppe-102056	Prunus persica	40.58	2.00e-58	219.00
IUUC-Pva-102859	Pteropus vampyrus	98.69	6.00e-167	579.00
IUUC-Pte-104236	Pyrenophora teres	35.56	2.00e-25	109.00
IUUC-Rno-105826	Rattus norvegicus	96.72	8.00e-165	572.00
IUUC-Sha-106660	Sarcophilus harrisii	91.69	5.00e-152	530.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.22	4.00e-36	144.00
IUUC-Spo-108244	Schizosaccharomyces pombe	31.07	1.00e-34	140.00
IUUC-Smo-109234	Selaginella moellendorffii	43.14	2.00e-61	229.00
IUUC-Sit-110048	Setaria italica	37.20	6.00e-41	160.00
IUUC-Sly-111618	Solanum lycopersicum	38.78	2.00e-52	199.00
IUUC-Stu-112543	Solanum tuberosum	39.10	1.00e-55	209.00
IUUC-Sar-113743	Sorex araneus	77.70	1.00e-129	455.00
IUUC-Sbi-114309	Sorghum bicolor	38.91	4.00e-42	165.00
IUUC-Ssc-115560	Sus scrofa	92.46	6.00e-154	536.00
IUUC-Tgu-117300	Taeniopygia guttata	92.79	2.00e-160	558.00
IUUC-Tru-117933	Takifugu rubripes	84.26	7.00e-149	519.00
IUUC-Tsy-119574	Tarsius syrichta	87.87	7.00e-144	503.00
IUUC-Tni-120191	Tetraodon nigroviridis	86.92	1.00e-112	399.00
IUUC-Tca-120983	Theobroma cacao	40.13	3.00e-57	215.00
IUUC-Tae-124056	Triticum aestivum	36.48	5.00e-50	191.00
IUUC-Tur-126711	Triticum urartu	36.36	5.00e-49	187.00
IUUC-Tme-127066	Tuber melanosporum	33.46	3.00e-33	135.00
IUUC-Tbe-127802	Tupaia belangeri	99.34	3.00e-169	587.00
IUUC-Ttr-128861	Tursiops truncatus	97.17	2.00e-55	209.00
IUUC-Vda-129720	Verticillium dahliae	28.42	1.00e-22	100.00
IUUC-Vpa-130618	Vicugna pacos	94.74	2.00e-134	471.00
IUUC-Vvi-130981	Vitis vinifera	40.71	3.00e-56	211.00
IUUC-Xtr-132460	Xenopus tropicalis	85.90	5.00e-146	509.00
IUUC-Xma-134154	Xiphophorus maculatus	85.57	1.00e-143	502.00
IUUC-Yli-134554	Yarrowia lipolytica	27.90	8.00e-20	90.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence