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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-045893
Ensembl Protein ID ENSP00000383911.3
UniProt Accession Q8NBM4; B3KNV7; Q0VAB5; Q5W0W6; Q5W0W9; Q6GQR2; Q6P4B0; Q8N2E8; Q96NW2; UBAC2_HUMAN
Genbank Protein ID BAB70757.1; BAG51469.1; BAC11609.1; BAC11665.1; CAH70935.1; CAH70935.1; CAH70935.1; CAH70936.1; CAH70936.1; CAH70936.1; CAH70937.1; CAH70937.1; CAH70937.1; CAI16940.1; CAI16940.1; CAI16940.1; CAI16941.1; CAI16941.1; CAI16941.1; CAI16943.1; CAI16943.1; CAI16943.1; CAI14300.1; CAI14300.1; CAI14300.1; CAI14301.1; CAI14301.1; CAI14301.1; CAI14303.1; CAI14303.1; CAI14303.1; AAH63559.1; AAH72674.1; AAI21139.1; AAI21140.1
Protein Name Ubiquitin-associated domain-containing protein 2; Phosphoglycerate dehydrogenase-like protein 1
Genbank Nucleotide ID AK054563; AK055110; AK075419; AK075516; AL136961; AL159981; AL160155; AL136961; AL159981; AL160155; AL136961; AL159981; AL160155; AL159981; AL136961; AL160155; AL159981; AL136961; AL160155; AL159981; AL136961; AL160155; AL160155; AL136961; AL159981; AL160155; AL136961; AL159981; AL160155; AL136961; AL159981; BC063559; BC072674; BC121138; BC121139
Gene Name UBAC2; PHGDHL1; PSEC0110
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000134882.15 ENST00000355700.9 ENSP00000347928.5
ENSG00000134882.15 ENST00000403766.7 ENSP00000383911.3
ENSG00000134882.15 ENST00000376440.6 ENSP00000365623.2
ENSG00000134882.15 ENST00000457666.1 ENSP00000402249.1
ENSG00000134882.15 ENST00000474510.2 ENSP00000481260.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Disease-associated Information
GWASdb
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDBioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UBA UBA 23161479
Classification
Family E-value Score Start End
UBD/Alpha-Helix/UBA 9.70e-13 49.5 306 344
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBA
   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           +e++++ l+eMGF+r +al+aLra+nn+l++A+++Ll +
   Q: 306  SEEQVARLMEMGFSRGDALEALRASNNDLNVATNFLLQH 344
           79**********************************976 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets.
 Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets.
Protein Sequence
(Fasta)
MFTSTGSSGL YKAPLSKSLL LVPSALSLLL ALLLPHCQKL FVYDLHAVKN DFQIWRLICG 60
RIICLDLKDT FCSSLLIYNF RIFERRYGSR KFASFLLGSW VLSALFDFLL IEAMQYFFGI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045893|UBD,UBA|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGTTCGTCA GCGGCGAGTG GCCTCGCGGC GCCGGATTCG TCGCTCCGCC AAGAGTGCGC 60
CTGCGCGGTC GCTGGGGCTC GCACTTCAGC TTCCCCTCCC CCGGCGCCCT CTGGGGCTCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045893|UBD,UBA|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0325--Glycoprotein
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR022764--Peptidase_S54_rhomboid_dom
IPR015940--UBA
IPR009060--UBA-like
PROSITE

PS50030--UBA
Pfam

PF00627--UBA
SMART

SM00165--UBA
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0043130--F:ubiquitin binding
GO:1904153--P:negative regulation of retrograde protein transport, ER to cytosol
GO:0070972--P:protein localization to endoplasmic reticulum
KEGG hsa:337867
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002272 Ailuropoda melanoleuca 89.55 1.00e-161 561.00
IUUC-Atr-002884 Amborella trichopoda 31.03 2.00e-06 45.80
IUUC-Apl-004075 Anas platyrhynchos 80.23 1.00e-152 532.00
IUUC-Aca-004595 Anolis carolinensis 72.75 1.00e-131 462.00
IUUC-Aly-006411 Arabidopsis lyrata 28.28 4.00e-16 78.60
IUUC-Ath-007083 Arabidopsis thaliana 26.98 2.00e-21 95.90
IUUC-Ago-007789 Ashbya gossypii 28.43 2.00e-04 39.70
IUUC-Acl-008340 Aspergillus clavatus 29.47 4.00e-04 38.90
IUUC-Afu-009037 Aspergillus fumigatus 26.80 1.00e-04 40.80
IUUC-Ang-009777 Aspergillus niger 28.00 5.00e-06 44.70
IUUC-Ame-011242 Astyanax mexicanus 58.74 4.00e-53 201.00
IUUC-Bgr-012021 Blumeria graminis 27.48 2.00e-06 46.60
IUUC-Bta-013487 Bos taurus 87.25 1.00e-161 561.00
IUUC-Bci-013918 Botrytis cinerea 27.03 1.00e-09 57.00
IUUC-Bdi-014757 Brachypodium distachyon 30.77 3.00e-24 105.00
IUUC-Bol-015531 Brassica oleracea 30.82 3.00e-12 65.90
IUUC-Bra-017181 Brassica rapa 32.08 1.00e-13 70.10
IUUC-Cja-018818 Callithrix jacchus 97.68 2.00e-176 611.00
IUUC-Cfa-021174 Canis familiaris 88.99 9.00e-162 562.00
IUUC-Cpo-021964 Cavia porcellus 92.75 7.00e-164 569.00
IUUC-Cre-022898 Chlamydomonas reinhardtii 32.32 2.00e-08 53.10
IUUC-Csa-024015 Chlorocebus sabaeus 98.55 2.00e-177 614.00
IUUC-Cho-024706 Choloepus hoffmanni 82.90 6.00e-141 493.00
IUUC-Cgl-026433 Colletotrichum gloeosporioides 26.72 1.00e-09 57.00
IUUC-Cne-026916 Cryptococcus neoformans 28.14 1.00e-04 40.80
IUUC-Dre-027633 Danio rerio 59.54 4.00e-101 361.00
IUUC-Dno-029418 Dasypus novemcinctus 89.86 3.00e-163 567.00
IUUC-Dor-030432 Dipodomys ordii 88.99 4.00e-170 590.00
IUUC-Dse-031426 Dothistroma septosporum 23.81 2.00e-11 63.20
IUUC-Ete-032599 Echinops telfairi 75.65 6.00e-126 443.00
IUUC-Eca-034280 Equus caballus 89.35 5.00e-157 546.00
IUUC-Eeu-034998 Erinaceus europaeus 87.54 2.00e-159 555.00
IUUC-Fca-036332 Felis catus 86.26 1.00e-157 548.00
IUUC-Fal-036680 Ficedula albicollis 79.13 6.00e-151 526.00
IUUC-Fox-037932 Fusarium oxysporum 21.68 2.00e-07 49.30
IUUC-Fso-038343 Fusarium solani 39.02 2.00e-04 39.30
IUUC-Gmo-039606 Gadus morhua 58.38 1.00e-83 303.00
IUUC-Ggr-039926 Gaeumannomyces graminis 27.38 1.00e-04 40.40
IUUC-Gga-041116 Gallus gallus 76.30 9.00e-141 493.00
IUUC-Gac-041765 Gasterosteus aculeatus 55.20 1.00e-83 303.00
IUUC-Gma-043400 Glycine max 25.44 4.00e-15 75.10
IUUC-Ggo-045366 Gorilla gorilla 99.42 7.00e-179 619.00
IUUC-Hvu-047737 Hordeum vulgare 28.28 3.00e-11 62.40
IUUC-Itr-048679 Ictidomys tridecemlineatus 92.52 1.00e-77 281.00
IUUC-Lpe-051354 Leersia perrieri 31.21 7.00e-14 72.80
IUUC-Loc-052511 Lepisosteus oculatus 65.12 4.00e-109 387.00
IUUC-Laf-053414 Loxodonta africana 87.25 1.00e-158 552.00
IUUC-Mcc-055111 Macaca mulatta 99.13 2.00e-178 617.00
IUUC-Meu-056905 Macropus eugenii 78.00 2.00e-117 414.00
IUUC-Mor-057083 Magnaporthe oryzae 25.43 9.00e-06 43.90
IUUC-Mpo-057326 Magnaporthe poae 28.67 7.00e-05 41.20
IUUC-Mtr-057918 Medicago truncatula 26.37 1.00e-17 83.60
IUUC-Mla-058868 Melampsora laricipopulina 26.75 2.00e-04 39.70
IUUC-Mga-059639 Meleagris gallopavo 77.85 3.00e-63 233.00
IUUC-Mvi-060380 Microbotryum violaceum 34.04 6.00e-02 32.00
IUUC-Mmr-061267 Microcebus murinus 91.05 9.00e-144 502.00
IUUC-Mdo-062640 Monodelphis domestica 82.66 4.00e-152 530.00
IUUC-Mmu-063305 Mus musculus 88.99 2.00e-160 558.00
IUUC-Mac-064533 Musa acuminata 26.39 2.00e-10 59.70
IUUC-Mpu-066519 Mustela putorius furo 87.83 6.00e-163 566.00
IUUC-Mlu-067419 Myotis lucifugus 90.23 1.00e-103 368.00
IUUC-Nfi-068304 Neosartorya fischeri 27.37 1.00e-03 37.40
IUUC-Ncr-068703 Neurospora crassa 26.53 2.00e-06 46.20
IUUC-Nle-070130 Nomascus leucogenys 98.07 5.00e-156 543.00
IUUC-Opr-070252 Ochotona princeps 92.75 2.00e-168 584.00
IUUC-Ont-072624 Oreochromis niloticus 58.31 3.00e-103 368.00
IUUC-Oan-072843 Ornithorhynchus anatinus 83.15 2.00e-71 261.00
IUUC-Ocu-073940 Oryctolagus cuniculus 93.33 2.00e-167 581.00
IUUC-Oba-075875 Oryza barthii 31.88 2.00e-15 76.60
IUUC-Obr-076147 Oryza brachyantha 27.85 4.00e-22 98.60
IUUC-Ogl-077826 Oryza glaberrima 28.52 1.00e-21 97.10
IUUC-Ogu-078996 Oryza glumaepatula 28.67 1.00e-20 93.20
IUUC-Oin-079646 Oryza indica 31.88 1.00e-15 77.00
IUUC-Olo-081041 Oryza longistaminata 32.50 8.00e-15 75.50
IUUC-Ome-081238 Oryza meridionalis 29.29 3.00e-23 101.00
IUUC-Oni-082310 Oryza nivara 28.96 5.00e-20 91.30
IUUC-Opu-083821 Oryza punctata 31.25 1.00e-14 72.80
IUUC-Oru-084586 Oryza rufipogon 28.67 9.00e-21 94.00
IUUC-Osa-085823 Oryza sativa 32.54 5.00e-15 75.10
IUUC-Ola-086714 Oryzias latipes 50.14 3.00e-61 228.00
IUUC-Oga-088600 Otolemur garnettii 91.94 1.00e-163 568.00
IUUC-Oar-090421 Ovis aries 87.74 2.00e-156 545.00
IUUC-Ptr-091509 Pan troglodytes 100.00 1.00e-180 625.00
IUUC-Pan-092468 Papio anubis 99.03 5.00e-174 603.00
IUUC-Psi-093075 Pelodiscus sinensis 78.55 2.00e-145 508.00
IUUC-Pno-095028 Phaeosphaeria nodorum 29.79 3.00e-03 35.80
IUUC-Ppa-095918 Physcomitrella patens 26.39 2.00e-20 92.80
IUUC-Pfo-096398 Poecilia formosa 54.49 2.00e-85 309.00
IUUC-Pab-097915 Pongo abelii 99.35 4.00e-175 607.00
IUUC-Pop-098933 Populus trichocarpa 27.05 2.00e-20 92.80
IUUC-Pca-100602 Procavia capensis 76.52 4.00e-131 461.00
IUUC-Ppe-101164 Prunus persica 26.76 8.00e-20 90.90
IUUC-Pva-102466 Pteropus vampyrus 91.59 2.00e-161 561.00
IUUC-Pgr-103488 Puccinia graminis 28.00 6.00e-08 50.80
IUUC-Pte-104413 Pyrenophora teres 30.85 1.00e-04 40.40
IUUC-Pyt-104659 Pyrenophora triticirepentis 30.85 2.00e-04 39.30
IUUC-Rno-105226 Rattus norvegicus 88.99 6.00e-162 563.00
IUUC-Sce-106268 Saccharomyces cerevisiae 32.08 1.10e-02 34.30
IUUC-Sha-106739 Sarcophilus harrisii 82.39 1.00e-146 512.00
IUUC-Sja-107960 Schizosaccharomyces japonicus 25.31 3.00e-05 42.40
IUUC-Ssl-108440 Sclerotinia sclerotiorum 27.47 3.00e-11 62.00
IUUC-Smo-108945 Selaginella moellendorffii 28.44 7.00e-10 57.80
IUUC-Sit-110720 Setaria italica 28.90 8.00e-19 87.80
IUUC-Sly-111445 Solanum lycopersicum 25.81 4.00e-16 78.60
IUUC-Stu-112541 Solanum tuberosum 26.39 1.00e-15 77.40
IUUC-Sar-113380 Sorex araneus 71.92 3.00e-97 347.00
IUUC-Sbi-113779 Sorghum bicolor 25.67 7.00e-20 90.90
IUUC-Ssc-115286 Sus scrofa 92.59 2.00e-84 305.00
IUUC-Tgu-117075 Taeniopygia guttata 78.98 8.00e-146 509.00
IUUC-Tru-118110 Takifugu rubripes 55.21 7.00e-90 323.00
IUUC-Tsy-118933 Tarsius syrichta 82.07 5.00e-133 467.00
IUUC-Tni-119811 Tetraodon nigroviridis 55.87 2.00e-91 329.00
IUUC-Tca-121053 Theobroma cacao 27.80 4.00e-17 81.60
IUUC-Tre-122152 Trichoderma reesei 28.32 3.00e-08 52.00
IUUC-Tvi-122334 Trichoderma virens 31.48 3.00e-08 52.40
IUUC-Tae-125696 Triticum aestivum 28.57 2.00e-21 96.70
IUUC-Tur-126868 Triticum urartu 31.61 1.00e-14 73.20
IUUC-Tme-127059 Tuber melanosporum 26.15 2.00e-07 49.70
IUUC-Tbe-127867 Tupaia belangeri 57.97 3.00e-95 341.00
IUUC-Ttr-128543 Tursiops truncatus 91.59 9.00e-169 585.00
IUUC-Uma-129462 Ustilago maydis 25.10 1.00e-06 47.80
IUUC-Vda-129740 Verticillium dahliae 25.56 5.00e-08 51.60
IUUC-Vpa-130623 Vicugna pacos 78.84 4.00e-132 464.00
IUUC-Vvi-131299 Vitis vinifera 31.36 9.00e-15 74.30
IUUC-Xtr-132867 Xenopus tropicalis 57.00 2.00e-113 402.00
IUUC-Xma-133270 Xiphophorus maculatus 59.21 7.00e-87 313.00
IUUC-Yli-134415 Yarrowia lipolytica 26.42 1.00e-06 47.00
IUUC-Zma-135827 Zea mays 25.59 3.00e-20 92.40
Created Date 25-Jun-2017

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