iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073483

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01281914

Gene Name

USP7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000008251.3	ENSOANT00000013113.3	ENSOANP00000013111.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-68	230.7	167	473

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 167  VGLKNQGATCYMNSLLQTLFFTNQLRKAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 246
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c++ d +s r+e+ +d++l+++g
   Q: 247  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKDVDYRSDRREDYYDIQLSIKG 309
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ +lP+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 310  KK-----NIFESFIDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 392
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           ++ k+  + +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 393  TDPKD--PANYILHAVLVHSGDNHGGHYVVYLNPkGDGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 473
           88777..*************************9834566************86666664446*******************87 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MADGHNTTEE DMEDDTSWRS EATFQFTVER FSRLSESVLS PPCFVRNLPW KIMVMPRFYP 60
DRPHQKSVGF FLQCNAESDS TSWSCHAQAV LKIINYKDDE KSFSRRISHL FFHKENDWGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAAGTTAC TAGCTCCCTT CACTGAGGAC ATGGACTACT ATCTCCACAC TAACCAGGGA 60
TGCAGTAATT AAAAGTCTCC AGAGGTGGTA CGGCCACGAA GTACACCATC TGACATGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0010216--P:maintenance of DNA methylation
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0050821--P:protein stabilization
GO:0006283--P:transcription-coupled nucleotide-excision repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

oaa:100074824

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	32.97	2.00e-142	499.00
IUUC-Aml-002408	Ailuropoda melanoleuca	98.10	0.00e+00	2151.00
IUUC-Atr-003067	Amborella trichopoda	36.54	1.00e-122	433.00
IUUC-Apl-003558	Anas platyrhynchos	97.92	0.00e+00	2168.00
IUUC-Aca-004518	Anolis carolinensis	91.92	0.00e+00	2028.00
IUUC-Aly-006453	Arabidopsis lyrata	36.73	8.00e-160	557.00
IUUC-Ath-006591	Arabidopsis thaliana	36.24	1.00e-155	543.00
IUUC-Ago-007849	Ashbya gossypii	32.88	7.00e-140	491.00
IUUC-Acl-008327	Aspergillus clavatus	34.20	3.00e-171	595.00
IUUC-Afl-008491	Aspergillus flavus	34.75	3.00e-165	575.00
IUUC-Afu-008804	Aspergillus fumigatus	35.13	2.00e-162	565.00
IUUC-Ang-009776	Aspergillus niger	34.98	2.00e-162	565.00
IUUC-Aor-009998	Aspergillus oryzae	34.01	6.00e-157	547.00
IUUC-Ate-010428	Aspergillus terreus	34.79	3.00e-165	575.00
IUUC-Ame-010903	Astyanax mexicanus	94.35	0.00e+00	2099.00
IUUC-Bgr-012132	Blumeria graminis	32.01	1.00e-145	509.00
IUUC-Bta-013192	Bos taurus	97.63	0.00e+00	2138.00
IUUC-Bci-013924	Botrytis cinerea	34.33	1.00e-151	530.00
IUUC-Bdi-014920	Brachypodium distachyon	35.73	6.00e-158	551.00
IUUC-Bol-015224	Brassica oleracea	36.49	1.00e-156	546.00
IUUC-Bra-017448	Brassica rapa	36.27	3.00e-156	545.00
IUUC-Cel-018219	Caenorhabditis elegans	34.13	5.00e-157	548.00
IUUC-Cja-019006	Callithrix jacchus	96.59	0.00e+00	2113.00
IUUC-Cfa-020361	Canis familiaris	98.01	0.00e+00	2146.00
IUUC-Cpo-022320	Cavia porcellus	97.63	0.00e+00	2139.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	44.05	3.00e-92	332.00
IUUC-Csa-024050	Chlorocebus sabaeus	97.82	0.00e+00	2144.00
IUUC-Cho-024434	Choloepus hoffmanni	88.76	0.00e+00	1414.00
IUUC-Cin-025689	Ciona intestinalis	55.53	0.00e+00	1199.00
IUUC-Csv-025963	Ciona savignyi	53.40	0.00e+00	1164.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.57	1.00e-152	533.00
IUUC-Cne-026968	Cryptococcus neoformans	36.56	0.00e+00	632.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.94	3.00e-116	413.00
IUUC-Dre-028510	Danio rerio	94.35	0.00e+00	2097.00
IUUC-Dno-029696	Dasypus novemcinctus	97.73	0.00e+00	2138.00
IUUC-Dor-030611	Dipodomys ordii	81.98	0.00e+00	902.00
IUUC-Dse-031433	Dothistroma septosporum	34.80	1.00e-147	516.00
IUUC-Dme-031583	Drosophila melanogaster	49.11	0.00e+00	1038.00
IUUC-Ete-033191	Echinops telfairi	95.64	0.00e+00	2095.00
IUUC-Eca-034122	Equus caballus	97.82	0.00e+00	2145.00
IUUC-Eeu-035292	Erinaceus europaeus	83.57	0.00e+00	675.00
IUUC-Fca-036377	Felis catus	98.10	0.00e+00	2149.00
IUUC-Fal-036964	Ficedula albicollis	98.01	0.00e+00	2171.00
IUUC-Fox-037695	Fusarium oxysporum	33.30	2.00e-160	559.00
IUUC-Fso-038084	Fusarium solani	33.64	1.00e-159	556.00
IUUC-Gmo-038644	Gadus morhua	94.12	0.00e+00	2096.00
IUUC-Ggr-040029	Gaeumannomyces graminis	33.51	5.00e-157	548.00
IUUC-Gga-040944	Gallus gallus	98.10	0.00e+00	2175.00
IUUC-Gac-041740	Gasterosteus aculeatus	94.60	0.00e+00	2100.00
IUUC-Gma-043300	Glycine max	36.63	1.00e-168	586.00
IUUC-Ggo-044947	Gorilla gorilla	97.73	0.00e+00	2142.00
IUUC-Hsa-046278	Homo sapiens	97.82	0.00e+00	2146.00
IUUC-Hvu-047749	Hordeum vulgare	36.54	1.00e-141	496.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	97.64	0.00e+00	1880.00
IUUC-Kpa-049121	Komagataella pastoris	31.12	2.00e-126	446.00
IUUC-Lch-049847	Latimeria chalumnae	97.06	0.00e+00	2144.00
IUUC-Lpe-051505	Leersia perrieri	35.69	5.00e-143	501.00
IUUC-Loc-052234	Lepisosteus oculatus	94.83	0.00e+00	1386.00
IUUC-Lma-053169	Leptosphaeria maculans	36.60	4.00e-168	585.00
IUUC-Laf-053566	Loxodonta africana	98.01	0.00e+00	2144.00
IUUC-Mcc-055549	Macaca mulatta	97.82	0.00e+00	2141.00
IUUC-Meu-056887	Macropus eugenii	88.39	0.00e+00	1281.00
IUUC-Mor-057149	Magnaporthe oryzae	34.69	4.00e-159	555.00
IUUC-Mpo-057536	Magnaporthe poae	33.61	7.00e-158	551.00
IUUC-Mtr-058583	Medicago truncatula	37.65	3.00e-164	572.00
IUUC-Mla-058899	Melampsora laricipopulina	37.42	5.00e-173	601.00
IUUC-Mga-060148	Meleagris gallopavo	98.10	0.00e+00	2175.00
IUUC-Mvi-060207	Microbotryum violaceum	37.82	0.00e+00	637.00
IUUC-Mmr-060946	Microcebus murinus	97.91	0.00e+00	2148.00
IUUC-Mdo-062079	Monodelphis domestica	91.78	0.00e+00	1947.00
IUUC-Mmu-063678	Mus musculus	97.44	0.00e+00	2130.00
IUUC-Mac-065416	Musa acuminata	37.55	5.00e-157	548.00
IUUC-Mpu-066744	Mustela putorius furo	97.73	0.00e+00	2142.00
IUUC-Mlu-067949	Myotis lucifugus	97.16	0.00e+00	2121.00
IUUC-Nfi-068342	Neosartorya fischeri	35.03	2.00e-162	566.00
IUUC-Ncr-068818	Neurospora crassa	34.51	2.00e-162	566.00
IUUC-Nle-070064	Nomascus leucogenys	97.73	0.00e+00	2142.00
IUUC-Opr-071001	Ochotona princeps	96.30	0.00e+00	1759.00
IUUC-Ont-072095	Oreochromis niloticus	94.16	0.00e+00	2098.00
IUUC-Ocu-073967	Oryctolagus cuniculus	96.97	0.00e+00	2055.00
IUUC-Oba-075811	Oryza barthii	34.23	2.00e-140	492.00
IUUC-Obr-076857	Oryza brachyantha	35.79	2.00e-153	536.00
IUUC-Ogl-077038	Oryza glaberrima	35.70	3.00e-151	529.00
IUUC-Ogu-078265	Oryza glumaepatula	34.10	6.00e-137	481.00
IUUC-Oin-079513	Oryza indica	35.33	2.00e-141	496.00
IUUC-Olo-080297	Oryza longistaminata	32.87	7.00e-125	441.00
IUUC-Ome-081879	Oryza meridionalis	36.41	4.00e-149	521.00
IUUC-Oni-082409	Oryza nivara	33.46	6.00e-141	494.00
IUUC-Opu-083199	Oryza punctata	35.73	2.00e-146	513.00
IUUC-Oru-085109	Oryza rufipogon	35.87	6.00e-145	508.00
IUUC-Osa-085418	Oryza sativa	36.44	8.00e-133	467.00
IUUC-Ola-086640	Oryzias latipes	94.41	0.00e+00	2090.00
IUUC-Olu-087874	Ostreococcus lucimarinus	33.49	2.00e-143	503.00
IUUC-Oga-089059	Otolemur garnettii	90.70	0.00e+00	1952.00
IUUC-Oar-089710	Ovis aries	97.63	0.00e+00	2139.00
IUUC-Ptr-091334	Pan troglodytes	97.73	0.00e+00	2142.00
IUUC-Pan-091717	Papio anubis	98.08	0.00e+00	2125.00
IUUC-Psi-093933	Pelodiscus sinensis	97.83	0.00e+00	2173.00
IUUC-Pma-094648	Petromyzon marinus	84.23	0.00e+00	1716.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.55	2.00e-151	529.00
IUUC-Ppa-096020	Physcomitrella patens	34.96	1.00e-162	566.00
IUUC-Pfo-096181	Poecilia formosa	93.97	0.00e+00	2095.00
IUUC-Pab-098231	Pongo abelii	95.17	0.00e+00	2070.00
IUUC-Pop-100083	Populus trichocarpa	36.75	1.00e-159	556.00
IUUC-Pca-100543	Procavia capensis	81.77	0.00e+00	971.00
IUUC-Ppe-101523	Prunus persica	36.04	6.00e-154	537.00
IUUC-Pva-102472	Pteropus vampyrus	96.68	0.00e+00	2095.00
IUUC-Pgr-103463	Puccinia graminis	37.07	9.00e-172	597.00
IUUC-Ptt-103716	Puccinia triticina	38.14	4.00e-169	588.00
IUUC-Pte-104360	Pyrenophora teres	36.42	2.00e-152	532.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	36.04	1.00e-150	526.00
IUUC-Rno-105816	Rattus norvegicus	97.25	0.00e+00	2135.00
IUUC-Sce-106230	Saccharomyces cerevisiae	30.02	5.00e-123	435.00
IUUC-Sha-107439	Sarcophilus harrisii	99.34	0.00e+00	2164.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	33.27	5.00e-139	488.00
IUUC-Spo-108019	Schizosaccharomyces pombe	34.72	2.00e-145	509.00
IUUC-Smo-109308	Selaginella moellendorffii	36.07	7.00e-153	534.00
IUUC-Sit-110367	Setaria italica	36.25	1.00e-158	553.00
IUUC-Sly-111337	Solanum lycopersicum	37.72	4.00e-163	568.00
IUUC-Stu-112387	Solanum tuberosum	37.13	1.00e-164	573.00
IUUC-Sar-113685	Sorex araneus	96.87	0.00e+00	2117.00
IUUC-Sbi-114037	Sorghum bicolor	36.77	1.00e-157	550.00
IUUC-Sre-115156	Sporisorium reilianum	38.61	0.00e+00	641.00
IUUC-Ssc-116297	Sus scrofa	97.82	0.00e+00	2145.00
IUUC-Tgu-116767	Taeniopygia guttata	97.82	0.00e+00	2165.00
IUUC-Tru-118208	Takifugu rubripes	94.03	0.00e+00	2066.00
IUUC-Tsy-119277	Tarsius syrichta	88.03	0.00e+00	658.00
IUUC-Tni-119890	Tetraodon nigroviridis	94.03	0.00e+00	2067.00
IUUC-Tca-121696	Theobroma cacao	36.82	1.00e-155	543.00
IUUC-Tre-122169	Trichoderma reesei	33.45	4.00e-153	535.00
IUUC-Tvi-122600	Trichoderma virens	34.12	8.00e-162	564.00
IUUC-Tae-125264	Triticum aestivum	36.14	2.00e-154	539.00
IUUC-Tur-126287	Triticum urartu	35.08	4.00e-149	521.00
IUUC-Tme-127045	Tuber melanosporum	35.53	4.00e-167	581.00
IUUC-Tbe-127696	Tupaia belangeri	86.64	3.00e-158	551.00
IUUC-Ttr-129161	Tursiops truncatus	97.91	0.00e+00	2139.00
IUUC-Uma-129535	Ustilago maydis	37.74	0.00e+00	652.00
IUUC-Vda-129708	Verticillium dahliae	32.78	1.00e-158	553.00
IUUC-Vvi-131048	Vitis vinifera	35.70	2.00e-158	553.00
IUUC-Xtr-132073	Xenopus tropicalis	93.19	0.00e+00	2041.00
IUUC-Xma-133949	Xiphophorus maculatus	93.79	0.00e+00	2088.00
IUUC-Yli-134527	Yarrowia lipolytica	32.72	8.00e-140	491.00
IUUC-Zma-135855	Zea mays	36.57	8.00e-148	517.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence