iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-002580

Ensembl Protein ID

ERM98397

UniProt Accession

W1NRC0; W1NRC0_AMBTC

Genbank Protein ID

ERM98397.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

KI395332

Gene Name

AMTR_s00072p00067600

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00072p00067600	ERM98397	ERM98397

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.00e-50	171.0	308	854
UBD/Alpha-Helix/UBA	5.70e-16	58.5	731	769

Active Site

Position(s)	Description	Evidence
317	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
817	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeel........................................ 60
           tGl NlgN+CY+ S++Q++++++ + + + e    ++   ++p +p+ +l ++l kl + l                                        
   Q: 308  TGLINLGNSCYLASTMQVIFSTNAFCSRYYEnLSLKESFGRAPADPTLDLNMQLSKLAHGLlsgkysvpvqehtylllpevhcyalirpplaslipppvak 408
           7************************9988886444445556677777777777777777776666666666666666666666666666666666666666 PP
   S: 61   ..............................wkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeae 131
                                           ++++ + pr+++ ++++ ++efs+++qqDa Ef+ ++ldq+e+                          
   Q: 409  gknletwdpsghvehglgqiqylgqgkssaFIQSQEGIPPRMFKMVIAASHPEFSSMRQQDALEFFLHFLDQVERIN------------------------ 485
           666666666666666666655555554443367777*************************************9966........................ PP
   S: 132  ekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.............................slqdcLesftkeeelege 203
                k +   s+ F++ +++++ cl+ +  +  + + + lsl++p  + t+ke                              l++cL+sft++ee+++ 
   Q: 486  ---AGKPELDSSRCFKFGVEERLLCLSGKVAY-NKRTDYILSLNIPLTKATNKEqleafnklkeerrfegkeiaseeivrprvHLESCLASFTSPEEVHD- 581
           ...33444456799***********9977777.344556677777766666666679*****************************************97. PP
   S: 204  nkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts..................................... 267
             +y++  ++k++a k+ +l+++P++L+lh+ +f + ee+++++k++ ++++p+ +d+s + ++                                     
   Q: 582  --FYSTALNAKTTAIKTAGLTTFPDYLVLHMRKF-VMEEGWVPKKLDVYIDVPDIIDISYMRSKglqpgeellpesdsekggpvkpyvnedivsqltsmgf 679
           ..********************************.67889*******************666668888888887777776666666666666666666666 PP
   S: 268  .........................................peekqke..................................................... 274
                                                    +                                                           
   Q: 680  pllhcekaaiytsnvgveeamnwllahmedpdidtpisqevE-----Gagnllaavdemclqtlvsfgfspdlarkalmssggdvekatdwifshpdasat 775
           666666666666666666666666666555555555555550.....055555555555555555555555555555666666666666666666666666 PP
   S: 275  .....................kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                                + +Y+L+a v+H+G s+++GHYva+v + +g+W+ f+D+kV ++   +  +   + +Y++f++r
   Q: 776  mdmdatsseteptsdqglpdgDGRYKLMAFVSHMGtSTHCGHYVAHVLK-DGRWVIFNDKKVAAS--VDPPR---DMGYIYFFER 854
           677777777778888889999****************************.9***********998..45566...8999999987 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           de+ l+ lv+ GF++++a++aL ++++++e A+++++++
   Q: 731  DEMCLQTLVSFGFSPDLARKALMSSGGDVEKATDWIFSH 769
           899**********************************97 PP

Organism

Amborella trichopoda

Protein Sequence
(Fasta)

MELLRSHLSK LRIPTPSHRV YKQECCISFD TPRSEGGLFV DMNSFLAFGK DYVDWNYEKT 60
GNPVYFHIKQ TRKAVPEDRP LKKPTRLAIG VEGGFETNEP EYEDNYSIII LPDYVMLPFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTTGC TGAGGTCTCA CCTCTCCAAA CTTAGAATCC CCACTCCTTC GCATCGTGTT 60
TACAAGCAAG AATGCTGCAT TTCTTTTGAT ACACCAGTAA GCTTCTTTCC ATTAATTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0009793--P:embryo development ending in seed dormancy
GO:0016579--P:protein deubiquitination
GO:0048767--P:root hair elongation
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	62.59	7.00e-148	516.00
IUUC-Aml-002104	Ailuropoda melanoleuca	51.54	4.00e-110	391.00
IUUC-Apl-003774	Anas platyrhynchos	46.05	0.00e+00	718.00
IUUC-Aca-004634	Anolis carolinensis	41.76	0.00e+00	645.00
IUUC-Aly-005727	Arabidopsis lyrata	66.28	0.00e+00	1144.00
IUUC-Ath-006974	Arabidopsis thaliana	66.16	0.00e+00	1145.00
IUUC-Ago-007890	Ashbya gossypii	30.11	2.00e-43	169.00
IUUC-Acl-008057	Aspergillus clavatus	32.90	1.00e-116	412.00
IUUC-Afl-008547	Aspergillus flavus	36.01	3.00e-103	367.00
IUUC-Afu-008805	Aspergillus fumigatus	32.64	9.00e-103	366.00
IUUC-Ani-009441	Aspergillus nidulans	34.65	2.00e-89	322.00
IUUC-Ang-009720	Aspergillus niger	36.81	2.00e-60	226.00
IUUC-Aor-010111	Aspergillus oryzae	33.49	2.00e-115	409.00
IUUC-Ate-010531	Aspergillus terreus	30.98	5.00e-90	324.00
IUUC-Ame-011470	Astyanax mexicanus	41.58	0.00e+00	656.00
IUUC-Bgr-012183	Blumeria graminis	32.15	2.00e-103	369.00
IUUC-Bta-013179	Bos taurus	45.40	0.00e+00	736.00
IUUC-Bci-013858	Botrytis cinerea	32.88	2.00e-117	416.00
IUUC-Bdi-014904	Brachypodium distachyon	74.54	1.00e-177	615.00
IUUC-Bol-015296	Brassica oleracea	65.89	0.00e+00	1144.00
IUUC-Bra-017619	Brassica rapa	63.94	0.00e+00	1125.00
IUUC-Cel-018625	Caenorhabditis elegans	35.73	2.00e-63	236.00
IUUC-Cja-019063	Callithrix jacchus	45.08	0.00e+00	726.00
IUUC-Cfa-020976	Canis familiaris	52.97	9.00e-113	400.00
IUUC-Cpo-022265	Cavia porcellus	52.44	3.00e-113	401.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	36.59	4.00e-101	360.00
IUUC-Csa-024078	Chlorocebus sabaeus	42.12	0.00e+00	649.00
IUUC-Cho-024522	Choloepus hoffmanni	34.30	3.00e-121	427.00
IUUC-Cin-025411	Ciona intestinalis	47.27	9.00e-93	333.00
IUUC-Csv-026347	Ciona savignyi	39.00	2.00e-165	574.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	33.10	1.00e-102	366.00
IUUC-Cne-026831	Cryptococcus neoformans	33.64	1.00e-111	396.00
IUUC-Cme-027335	Cyanidioschyzon merolae	27.45	7.00e-54	204.00
IUUC-Dre-027651	Danio rerio	41.14	0.00e+00	683.00
IUUC-Dno-029034	Dasypus novemcinctus	46.29	0.00e+00	738.00
IUUC-Dor-030130	Dipodomys ordii	35.37	2.00e-99	355.00
IUUC-Dse-031467	Dothistroma septosporum	33.22	3.00e-105	375.00
IUUC-Dme-032075	Drosophila melanogaster	40.54	1.00e-172	598.00
IUUC-Ete-032865	Echinops telfairi	42.65	0.00e+00	656.00
IUUC-Eca-033568	Equus caballus	41.95	1.00e-177	615.00
IUUC-Eeu-035304	Erinaceus europaeus	43.41	0.00e+00	659.00
IUUC-Fca-035515	Felis catus	52.32	2.00e-112	399.00
IUUC-Fal-037271	Ficedula albicollis	47.22	0.00e+00	707.00
IUUC-Fox-037745	Fusarium oxysporum	33.53	2.00e-106	378.00
IUUC-Fso-038158	Fusarium solani	36.28	2.00e-63	236.00
IUUC-Gmo-039071	Gadus morhua	42.84	0.00e+00	652.00
IUUC-Ggr-040098	Gaeumannomyces graminis	31.47	7.00e-93	333.00
IUUC-Gga-040635	Gallus gallus	46.04	0.00e+00	753.00
IUUC-Gac-042528	Gasterosteus aculeatus	43.42	0.00e+00	656.00
IUUC-Gma-043614	Glycine max	67.37	0.00e+00	1121.00
IUUC-Ggo-044602	Gorilla gorilla	45.74	0.00e+00	739.00
IUUC-Hsa-045959	Homo sapiens	45.74	0.00e+00	739.00
IUUC-Hvu-047563	Hordeum vulgare	65.23	6.00e-147	513.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	52.58	3.00e-113	401.00
IUUC-Kpa-049156	Komagataella pastoris	29.69	1.00e-94	340.00
IUUC-Lch-049648	Latimeria chalumnae	45.29	0.00e+00	706.00
IUUC-Lpe-051523	Leersia perrieri	71.70	9.00e-167	579.00
IUUC-Loc-052072	Lepisosteus oculatus	42.03	0.00e+00	656.00
IUUC-Lma-053216	Leptosphaeria maculans	32.99	2.00e-103	370.00
IUUC-Laf-054327	Loxodonta africana	45.63	0.00e+00	739.00
IUUC-Mcc-055443	Macaca mulatta	45.63	0.00e+00	737.00
IUUC-Meu-056298	Macropus eugenii	46.54	3.00e-144	504.00
IUUC-Mor-057106	Magnaporthe oryzae	33.49	2.00e-113	402.00
IUUC-Mpo-057589	Magnaporthe poae	32.09	3.00e-95	342.00
IUUC-Mtr-058680	Medicago truncatula	69.63	0.00e+00	1188.00
IUUC-Mla-058903	Melampsora laricipopulina	32.83	6.00e-101	360.00
IUUC-Mga-059669	Meleagris gallopavo	45.68	0.00e+00	707.00
IUUC-Mvi-060476	Microbotryum violaceum	33.26	3.00e-99	355.00
IUUC-Mmr-060575	Microcebus murinus	45.63	0.00e+00	737.00
IUUC-Mdo-062183	Monodelphis domestica	45.45	0.00e+00	731.00
IUUC-Mmu-063592	Mus musculus	45.51	0.00e+00	739.00
IUUC-Mac-065634	Musa acuminata	67.04	0.00e+00	1154.00
IUUC-Mpu-066082	Mustela putorius furo	46.25	0.00e+00	740.00
IUUC-Mlu-067345	Myotis lucifugus	45.46	0.00e+00	735.00
IUUC-Nfi-068558	Neosartorya fischeri	33.54	9.00e-113	399.00
IUUC-Ncr-068960	Neurospora crassa	31.42	2.00e-100	358.00
IUUC-Nle-070173	Nomascus leucogenys	46.59	0.00e+00	743.00
IUUC-Opr-070556	Ochotona princeps	45.51	0.00e+00	747.00
IUUC-Ont-071502	Oreochromis niloticus	44.43	0.00e+00	667.00
IUUC-Oan-072959	Ornithorhynchus anatinus	53.07	5.00e-64	236.00
IUUC-Ocu-074861	Oryctolagus cuniculus	46.36	0.00e+00	750.00
IUUC-Oba-075109	Oryza barthii	70.98	2.00e-166	578.00
IUUC-Obr-076292	Oryza brachyantha	73.30	1.00e-177	615.00
IUUC-Ogl-077065	Oryza glaberrima	73.82	6.00e-178	616.00
IUUC-Ogu-078776	Oryza glumaepatula	70.50	5.00e-169	587.00
IUUC-Oin-080048	Oryza indica	73.30	4.00e-177	613.00
IUUC-Olo-080711	Oryza longistaminata	71.22	3.00e-164	571.00
IUUC-Ome-081506	Oryza meridionalis	71.22	1.00e-164	572.00
IUUC-Oni-082320	Oryza nivara	70.74	4.00e-166	577.00
IUUC-Opu-083801	Oryza punctata	71.47	2.00e-167	581.00
IUUC-Oru-085139	Oryza rufipogon	70.50	1.00e-164	572.00
IUUC-Osa-085713	Oryza sativa	74.08	5.00e-179	620.00
IUUC-Ola-086951	Oryzias latipes	42.40	0.00e+00	640.00
IUUC-Olu-087822	Ostreococcus lucimarinus	38.31	7.00e-156	543.00
IUUC-Oga-088734	Otolemur garnettii	42.18	0.00e+00	642.00
IUUC-Oar-089995	Ovis aries	44.80	0.00e+00	727.00
IUUC-Ptr-090640	Pan troglodytes	44.85	0.00e+00	735.00
IUUC-Pan-091974	Papio anubis	45.30	0.00e+00	730.00
IUUC-Psi-093957	Pelodiscus sinensis	46.26	0.00e+00	767.00
IUUC-Pma-094242	Petromyzon marinus	41.69	5.00e-89	320.00
IUUC-Pno-094835	Phaeosphaeria nodorum	34.55	3.00e-103	368.00
IUUC-Ppa-095901	Physcomitrella patens	61.68	0.00e+00	1088.00
IUUC-Pfo-097148	Poecilia formosa	43.92	0.00e+00	664.00
IUUC-Pab-098068	Pongo abelii	41.53	2.00e-177	615.00
IUUC-Pop-098855	Populus trichocarpa	70.15	0.00e+00	1149.00
IUUC-Pca-100738	Procavia capensis	42.75	2.00e-140	491.00
IUUC-Ppe-101315	Prunus persica	70.95	0.00e+00	1204.00
IUUC-Pva-102154	Pteropus vampyrus	45.34	0.00e+00	733.00
IUUC-Pgr-103343	Puccinia graminis	31.74	1.00e-90	326.00
IUUC-Ptt-103928	Puccinia triticina	28.46	2.00e-88	319.00
IUUC-Pte-104306	Pyrenophora teres	32.25	6.00e-97	347.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	35.41	9.00e-95	340.00
IUUC-Rno-105801	Rattus norvegicus	45.63	0.00e+00	743.00
IUUC-Sce-106304	Saccharomyces cerevisiae	31.24	1.00e-44	173.00
IUUC-Sha-107635	Sarcophilus harrisii	46.15	0.00e+00	729.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	31.79	1.00e-96	346.00
IUUC-Spo-108144	Schizosaccharomyces pombe	32.68	5.00e-111	394.00
IUUC-Smo-108848	Selaginella moellendorffii	58.69	0.00e+00	947.00
IUUC-Sit-110728	Setaria italica	74.02	9.00e-178	615.00
IUUC-Sly-111523	Solanum lycopersicum	76.25	0.00e+00	630.00
IUUC-Sar-113733	Sorex araneus	42.45	9.00e-88	317.00
IUUC-Sbi-114419	Sorghum bicolor	75.33	0.00e+00	628.00
IUUC-Sre-115225	Sporisorium reilianum	32.71	2.00e-102	366.00
IUUC-Ssc-115686	Sus scrofa	51.55	2.00e-111	395.00
IUUC-Tgu-117346	Taeniopygia guttata	45.98	0.00e+00	734.00
IUUC-Tru-118350	Takifugu rubripes	41.67	0.00e+00	651.00
IUUC-Tsy-119278	Tarsius syrichta	38.24	4.00e-155	540.00
IUUC-Tni-120658	Tetraodon nigroviridis	42.49	0.00e+00	641.00
IUUC-Tca-121585	Theobroma cacao	69.58	0.00e+00	1168.00
IUUC-Tre-122043	Trichoderma reesei	32.65	8.00e-99	353.00
IUUC-Tvi-122303	Trichoderma virens	33.49	9.00e-113	400.00
IUUC-Tae-123798	Triticum aestivum	72.70	9.00e-175	606.00
IUUC-Tur-126732	Triticum urartu	57.16	0.00e+00	955.00
IUUC-Tme-126909	Tuber melanosporum	33.83	9.00e-101	360.00
IUUC-Tbe-127261	Tupaia belangeri	43.47	5.00e-87	314.00
IUUC-Ttr-129119	Tursiops truncatus	51.89	8.00e-106	377.00
IUUC-Uma-129599	Ustilago maydis	32.97	8.00e-110	390.00
IUUC-Vda-129688	Verticillium dahliae	33.64	8.00e-113	400.00
IUUC-Vpa-130170	Vicugna pacos	46.72	6.00e-81	294.00
IUUC-Vvi-131116	Vitis vinifera	71.61	0.00e+00	1162.00
IUUC-Xtr-131953	Xenopus tropicalis	44.44	0.00e+00	693.00
IUUC-Xma-133837	Xiphophorus maculatus	43.92	0.00e+00	664.00
IUUC-Yli-134510	Yarrowia lipolytica	34.68	6.00e-57	214.00
IUUC-Zma-135786	Zea mays	75.33	2.00e-180	625.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence