iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Obr-076292

Ensembl Protein ID

OB01G14810.1

UniProt Accession

J3KWX5; J3KWX5_ORYBR

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OB01G14810	OB01G14810.1	OB01G14810.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.30e-55	187.6	311	794
UBD/Alpha-Helix/UBA	1.00e-15	58.0	671	709

Active Site

Position(s)	Description	Evidence
320	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
757	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkekln.eenpkepkgellkslqklfeelw........kskkkavsprellkalkkeaeefsgye 88
           tGl NlgN+CYm Sv+Q+++++ ++ + + ek++ k +   +p +p+ +l ++++kl + ++        ++ ++ + pr+++++++++++efs+++
   Q: 311  TGLVNLGNSCYMASVMQVMFSTLPFISRYYEKQSLKAAfTISPADPTMDLNMQMTKLAHGMLsgkyslpnQEGQEGIRPRMFKTVIAAKHPEFSSMR 407
           7*************************9999944443331446789999*************76666667688888********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkk 184
           qqDa +f+ +l+dq++++                           + +++ ++  + F++ ++++++c++ + ++ +r +  l+ls+p+++ ++  k
   Q: 408  QQDALDFFLHLIDQVDQAN--------------------------PGNHELNPF-TGFKFIIEERLQCPSGKVSYnKRSDYILSLSIPLHEATN--K 475
           ****************988..........................455555555.67***********98776664555555666666665554..4 PP
   S: 185  e.............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
           e                              l+ cL+sf+ +ee+ +   +y++  ++k++a k+ ++k++P++L+l++ +f + e++++++k++ +
   Q: 476  EqleafhekkaamdldgkevsneeivrprvPLEACLASFSGAEEVPD---FYSTALNSKTTAIKTAGFKSFPDYLVLQMRKF-VMEAGWVPKKLDVY 568
           4569*****************************************97...********************************.77889********* PP
   S: 253  vefpleLdlspfcts.................................................................................. 267
           +++p+ +d+s++ ++                                                                                  
   Q: 569  IDVPDIIDISHMRSKgiqpgeellpegaaggntaepaypvasedivshlasmgfnylhcqkaaistsntgveeamnwllshmddpdiddpiskdsqa 665
           **********999999999999999999999999999999999999999999998888888888888888888888888887777777777766666 PP
   S: 268  .....peekqke................................................................kkkYeLiavvvHsG.slssGH 294
                +     e                                                                + +Y+L+a v+H+G s+++GH
   Q: 666  aeqtvD-----EtsvqtlvsfgfqedvarkalaasggnieratdwifshpetsssaptvdsstsnmeaddahipdgSGRYKLMAFVSHMGtSTHCGH 757
           555550.....05555555555555556666666666666666666666666666677788888888999999999********************* PP
   S: 295  YvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           Yva++++ +g+W+ f+DskV ++   +  +   + +Y++f++r
   Q: 758  YVAHIRK-DGRWVIFNDSKVAAS--VDLPK---DMGYLYFFQR 794
           *******.9***********999..68888...999**99997 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           de  ++ lv+ GF ++ a++aL+a+++n+e+A+++++++
   Q: 671  DETSVQTLVSFGFQEDVARKALAASGGNIERATDWIFSH 709
           7999*********************************97 PP

Organism

Oryza brachyantha

Protein Sequence
(Fasta)

MDLLRSHLHR VRIPEPSDRI HKDECCVSFD TPRSEGGLYV DLSSFLGFGK EHVAWNYEKT 60
GNPVYLHIVQ RRKPEPDDEA DRPLKKPTLL AIGVEGGFND QEPEYDEAFE IVILPEFTSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTCCATCT CTTAATCTAA TCACACTCCT CTCCACCTCG TCGCCTCGCC GTCTCCACCA 60
CCAAAACCCT AGCCGGCGCC GCGCTCCTCC ACCCGCCGCC GCCCGCAGCC ATGGATCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

obr:102711307

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	81.78	0.00e+00	1263.00
IUUC-Aml-002104	Ailuropoda melanoleuca	47.66	0.00e+00	740.00
IUUC-Atr-002580	Amborella trichopoda	73.30	6.00e-178	617.00
IUUC-Apl-003774	Anas platyrhynchos	47.87	0.00e+00	724.00
IUUC-Aca-005368	Anolis carolinensis	49.64	0.00e+00	771.00
IUUC-Aly-005727	Arabidopsis lyrata	68.49	0.00e+00	1114.00
IUUC-Ath-006974	Arabidopsis thaliana	69.11	0.00e+00	1122.00
IUUC-Ago-007890	Ashbya gossypii	28.40	2.00e-70	259.00
IUUC-Acl-008057	Aspergillus clavatus	35.86	1.00e-118	419.00
IUUC-Afl-008547	Aspergillus flavus	35.76	1.00e-105	376.00
IUUC-Afu-008805	Aspergillus fumigatus	33.77	2.00e-102	365.00
IUUC-Ani-009441	Aspergillus nidulans	34.60	9.00e-92	330.00
IUUC-Ang-009720	Aspergillus niger	35.21	2.00e-108	386.00
IUUC-Aor-010111	Aspergillus oryzae	34.19	1.00e-114	406.00
IUUC-Ate-010531	Aspergillus terreus	32.52	4.00e-96	345.00
IUUC-Ame-011470	Astyanax mexicanus	42.04	0.00e+00	652.00
IUUC-Bgr-012183	Blumeria graminis	32.12	3.00e-102	365.00
IUUC-Bta-013179	Bos taurus	48.00	0.00e+00	748.00
IUUC-Bci-013858	Botrytis cinerea	33.50	5.00e-108	384.00
IUUC-Bdi-014904	Brachypodium distachyon	88.93	0.00e+00	1435.00
IUUC-Bol-015296	Brassica oleracea	69.14	0.00e+00	1111.00
IUUC-Bra-017939	Brassica rapa	69.61	0.00e+00	1116.00
IUUC-Cel-018625	Caenorhabditis elegans	33.17	2.00e-110	392.00
IUUC-Cja-019063	Callithrix jacchus	47.07	0.00e+00	737.00
IUUC-Cfa-020976	Canis familiaris	49.10	0.00e+00	758.00
IUUC-Cpo-022265	Cavia porcellus	48.86	0.00e+00	758.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	41.98	3.00e-119	421.00
IUUC-Csa-024078	Chlorocebus sabaeus	43.24	0.00e+00	663.00
IUUC-Cho-024522	Choloepus hoffmanni	35.50	4.00e-124	437.00
IUUC-Cin-025411	Ciona intestinalis	44.07	0.00e+00	657.00
IUUC-Csv-026347	Ciona savignyi	42.53	0.00e+00	630.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	31.64	2.00e-96	345.00
IUUC-Cne-026831	Cryptococcus neoformans	35.79	3.00e-114	405.00
IUUC-Cme-027335	Cyanidioschyzon merolae	29.52	8.00e-36	144.00
IUUC-Dre-027651	Danio rerio	42.46	0.00e+00	687.00
IUUC-Dno-029034	Dasypus novemcinctus	48.12	0.00e+00	750.00
IUUC-Dor-030130	Dipodomys ordii	37.56	5.00e-106	377.00
IUUC-Dse-031467	Dothistroma septosporum	34.19	2.00e-113	402.00
IUUC-Dme-032075	Drosophila melanogaster	44.72	0.00e+00	659.00
IUUC-Ete-032865	Echinops telfairi	44.90	0.00e+00	671.00
IUUC-Eca-034059	Equus caballus	48.01	0.00e+00	746.00
IUUC-Eeu-035304	Erinaceus europaeus	45.54	0.00e+00	665.00
IUUC-Fca-035515	Felis catus	48.00	0.00e+00	750.00
IUUC-Fal-037271	Ficedula albicollis	48.80	0.00e+00	709.00
IUUC-Fox-037745	Fusarium oxysporum	34.87	5.00e-114	404.00
IUUC-Fso-038158	Fusarium solani	33.41	1.00e-106	380.00
IUUC-Gmo-039071	Gadus morhua	44.31	0.00e+00	644.00
IUUC-Ggr-040098	Gaeumannomyces graminis	32.89	8.00e-102	363.00
IUUC-Gga-040635	Gallus gallus	48.13	0.00e+00	764.00
IUUC-Gac-042528	Gasterosteus aculeatus	43.57	0.00e+00	661.00
IUUC-Gma-043614	Glycine max	68.60	0.00e+00	1095.00
IUUC-Ggo-044602	Gorilla gorilla	48.12	0.00e+00	749.00
IUUC-Hsa-045959	Homo sapiens	48.12	0.00e+00	749.00
IUUC-Hvu-047563	Hordeum vulgare	84.79	0.00e+00	1073.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	47.54	0.00e+00	751.00
IUUC-Kpa-049156	Komagataella pastoris	31.57	2.00e-101	362.00
IUUC-Lch-049648	Latimeria chalumnae	49.10	0.00e+00	753.00
IUUC-Lpe-051523	Leersia perrieri	90.58	0.00e+00	1470.00
IUUC-Loc-052072	Lepisosteus oculatus	43.35	0.00e+00	659.00
IUUC-Lma-053216	Leptosphaeria maculans	34.32	9.00e-104	371.00
IUUC-Laf-054327	Loxodonta africana	48.00	0.00e+00	749.00
IUUC-Mcc-055443	Macaca mulatta	48.00	0.00e+00	745.00
IUUC-Meu-056298	Macropus eugenii	51.20	4.00e-156	544.00
IUUC-Mor-057106	Magnaporthe oryzae	33.66	4.00e-108	385.00
IUUC-Mpo-057589	Magnaporthe poae	33.01	7.00e-103	367.00
IUUC-Mtr-058680	Medicago truncatula	67.99	0.00e+00	1121.00
IUUC-Mla-058903	Melampsora laricipopulina	33.57	1.00e-105	376.00
IUUC-Mga-059669	Meleagris gallopavo	48.07	0.00e+00	720.00
IUUC-Mvi-060476	Microbotryum violaceum	33.77	4.00e-100	358.00
IUUC-Mmr-060575	Microcebus murinus	48.00	0.00e+00	745.00
IUUC-Mdo-062183	Monodelphis domestica	48.63	0.00e+00	753.00
IUUC-Mmu-063592	Mus musculus	48.12	0.00e+00	749.00
IUUC-Mac-065634	Musa acuminata	75.54	0.00e+00	681.00
IUUC-Mpu-066082	Mustela putorius furo	48.97	0.00e+00	751.00
IUUC-Mlu-067345	Myotis lucifugus	47.54	0.00e+00	742.00
IUUC-Nfi-068558	Neosartorya fischeri	34.81	3.00e-114	404.00
IUUC-Ncr-068960	Neurospora crassa	31.33	1.00e-96	346.00
IUUC-Nle-070173	Nomascus leucogenys	49.10	0.00e+00	756.00
IUUC-Opr-070556	Ochotona princeps	47.89	0.00e+00	759.00
IUUC-Ont-071502	Oreochromis niloticus	45.87	0.00e+00	664.00
IUUC-Oan-072959	Ornithorhynchus anatinus	53.95	6.00e-67	246.00
IUUC-Ocu-074861	Oryctolagus cuniculus	48.73	0.00e+00	763.00
IUUC-Oba-075109	Oryza barthii	92.33	0.00e+00	1482.00
IUUC-Ogl-077065	Oryza glaberrima	94.72	0.00e+00	1532.00
IUUC-Ogu-078776	Oryza glumaepatula	92.08	0.00e+00	1483.00
IUUC-Oin-080048	Oryza indica	94.09	0.00e+00	1511.00
IUUC-Olo-080711	Oryza longistaminata	90.27	0.00e+00	1370.00
IUUC-Ome-081506	Oryza meridionalis	92.31	0.00e+00	1381.00
IUUC-Oni-082320	Oryza nivara	89.85	0.00e+00	1473.00
IUUC-Opu-083801	Oryza punctata	92.70	0.00e+00	1461.00
IUUC-Oru-085139	Oryza rufipogon	89.73	0.00e+00	1469.00
IUUC-Osa-085713	Oryza sativa	94.72	0.00e+00	1534.00
IUUC-Ola-086951	Oryzias latipes	42.72	0.00e+00	649.00
IUUC-Olu-087822	Ostreococcus lucimarinus	41.53	2.00e-168	585.00
IUUC-Oga-088625	Otolemur garnettii	47.24	0.00e+00	741.00
IUUC-Oar-089995	Ovis aries	47.13	0.00e+00	739.00
IUUC-Ptr-090640	Pan troglodytes	47.18	0.00e+00	747.00
IUUC-Pan-091974	Papio anubis	47.19	0.00e+00	739.00
IUUC-Psi-093957	Pelodiscus sinensis	48.36	0.00e+00	769.00
IUUC-Pma-094242	Petromyzon marinus	48.84	2.00e-103	367.00
IUUC-Pno-094835	Phaeosphaeria nodorum	36.15	3.00e-97	348.00
IUUC-Ppa-095901	Physcomitrella patens	61.88	0.00e+00	1013.00
IUUC-Pfo-097148	Poecilia formosa	44.91	0.00e+00	664.00
IUUC-Pab-098068	Pongo abelii	43.38	5.00e-179	620.00
IUUC-Pop-098943	Populus trichocarpa	71.77	0.00e+00	1133.00
IUUC-Pca-100738	Procavia capensis	45.45	6.00e-141	493.00
IUUC-Ppe-101315	Prunus persica	70.41	0.00e+00	1118.00
IUUC-Pva-102154	Pteropus vampyrus	47.77	0.00e+00	741.00
IUUC-Pgr-103343	Puccinia graminis	33.19	1.00e-96	346.00
IUUC-Ptt-103928	Puccinia triticina	29.87	4.00e-91	328.00
IUUC-Pte-104306	Pyrenophora teres	35.21	1.00e-88	320.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	35.68	2.00e-93	335.00
IUUC-Rno-105801	Rattus norvegicus	48.36	0.00e+00	753.00
IUUC-Sce-106304	Saccharomyces cerevisiae	31.09	2.00e-68	253.00
IUUC-Sha-107635	Sarcophilus harrisii	49.52	0.00e+00	756.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	31.99	6.00e-91	327.00
IUUC-Spo-108144	Schizosaccharomyces pombe	32.56	1.00e-106	380.00
IUUC-Smo-108848	Selaginella moellendorffii	59.75	0.00e+00	925.00
IUUC-Sit-110728	Setaria italica	88.55	0.00e+00	1436.00
IUUC-Sly-111523	Solanum lycopersicum	68.24	0.00e+00	1139.00
IUUC-Sar-113733	Sorex araneus	45.23	7.00e-92	330.00
IUUC-Sbi-114419	Sorghum bicolor	88.81	0.00e+00	1427.00
IUUC-Sre-115225	Sporisorium reilianum	33.26	1.00e-105	376.00
IUUC-Ssc-115686	Sus scrofa	47.07	0.00e+00	744.00
IUUC-Tgu-117346	Taeniopygia guttata	47.55	0.00e+00	745.00
IUUC-Tru-118350	Takifugu rubripes	43.22	0.00e+00	652.00
IUUC-Tsy-119278	Tarsius syrichta	39.32	5.00e-160	557.00
IUUC-Tni-120658	Tetraodon nigroviridis	43.46	0.00e+00	641.00
IUUC-Tca-121585	Theobroma cacao	70.46	0.00e+00	1113.00
IUUC-Tre-122043	Trichoderma reesei	34.40	1.00e-112	399.00
IUUC-Tvi-122303	Trichoderma virens	34.15	3.00e-107	382.00
IUUC-Tae-123798	Triticum aestivum	87.30	0.00e+00	1411.00
IUUC-Tur-126732	Triticum urartu	81.51	0.00e+00	1314.00
IUUC-Tme-126909	Tuber melanosporum	34.50	8.00e-100	357.00
IUUC-Tbe-127261	Tupaia belangeri	41.23	3.00e-117	415.00
IUUC-Ttr-129119	Tursiops truncatus	53.39	1.00e-109	390.00
IUUC-Uma-129599	Ustilago maydis	34.49	2.00e-115	409.00
IUUC-Vda-129688	Verticillium dahliae	32.76	8.00e-104	370.00
IUUC-Vpa-130170	Vicugna pacos	37.10	1.00e-144	506.00
IUUC-Vvi-131116	Vitis vinifera	72.50	0.00e+00	1125.00
IUUC-Xtr-131953	Xenopus tropicalis	45.75	0.00e+00	707.00
IUUC-Xma-133837	Xiphophorus maculatus	44.79	0.00e+00	662.00
IUUC-Yli-134510	Yarrowia lipolytica	34.65	2.00e-107	382.00
IUUC-Zma-135786	Zea mays	86.54	0.00e+00	1362.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence