iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022036

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AAKN02009311

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000012261.3	ENSCPOT00000012377.2	ENSCPOP00000011026.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.00e-67	228.9	3	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakq 93
           +++wl+Le++P++ +++++++g++ ++q+ ++y++dpe l+++++pv+++lllF+i+ek+e +r+++   ++++++++d++++++f+kq
   Q: 3    GQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEE--EEKIKSQGQDVTSSVYFMKQ 89
           589*************************************************************766..5589**************** PP
   S: 94   vigNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfv 181
           +i+N+C+t++l+++++n++dk+ +   + l++++e++ ++sp ++a+ l+n ++++++h++ a+++++++p+ +       +k  +hf+
   Q: 90   TISNACGTIGLIHAIANNKDKMhFVWIQPLKKFLEESVSMSPGERARYLENYDAIRVTHETSAHEGQTEAPNID-------EKVDLHFI 171
           **********************99999********************************************877.......7899**** PP
   S: 182  syvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           ++v+++g+lyeldg+kpfP+++gk+++++ l+d+++v+++f+er    + de+rfn++a++a+
   Q: 172  ALVHVDGHLYELDGRKPFPINHGKTSDETLLEDAIEVCKKFMER----DPDELRFNAIALSAA 230
           ********************************************....***********9875 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MEGQRWLPLE ANPEVTNQFL KQLGLHPNWQ FVDVYGMDPE LLSMVPRPVC AVLLLFPITE 60
KYEVFRTEEE EKIKSQGQDV TSSVYFMKQT ISNACGTIGL IHAIANNKDK MHFVWIQPLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGGTC AGCGCTGGTT GCCGCTGGAG GCCAACCCTG AGGTGAGCCG GCTCGGGTCC 60
AGCTCTGAGG CCGCAGGAGG GGAGAGGGAG CCGGGATGCT GCCGCTGGTC CGTGTCAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	43.64	3.00e-52	197.00
IUUC-Aml-001344	Ailuropoda melanoleuca	96.52	2.00e-131	461.00
IUUC-Atr-002931	Amborella trichopoda	46.58	4.00e-47	181.00
IUUC-Apl-003949	Anas platyrhynchos	84.98	2.00e-100	357.00
IUUC-Aca-004924	Anolis carolinensis	80.95	2.00e-111	394.00
IUUC-Aly-005939	Arabidopsis lyrata	50.22	9.00e-58	216.00
IUUC-Ath-006827	Arabidopsis thaliana	50.00	5.00e-58	217.00
IUUC-Ago-007950	Ashbya gossypii	35.14	6.00e-28	117.00
IUUC-Acl-008305	Aspergillus clavatus	38.67	3.00e-38	151.00
IUUC-Afl-008611	Aspergillus flavus	39.83	2.00e-42	165.00
IUUC-Afu-008945	Aspergillus fumigatus	39.83	3.00e-42	164.00
IUUC-Ani-009339	Aspergillus nidulans	39.66	1.00e-42	166.00
IUUC-Ang-009691	Aspergillus niger	37.45	2.00e-40	158.00
IUUC-Aor-009961	Aspergillus oryzae	39.83	2.00e-42	166.00
IUUC-Ate-010316	Aspergillus terreus	40.43	2.00e-43	168.00
IUUC-Ame-011157	Astyanax mexicanus	72.17	2.00e-99	354.00
IUUC-Bgr-012125	Blumeria graminis	34.60	1.00e-35	143.00
IUUC-Bta-012673	Bos taurus	96.52	1.00e-131	461.00
IUUC-Bci-013734	Botrytis cinerea	37.61	3.00e-42	165.00
IUUC-Bdi-014330	Brachypodium distachyon	46.26	3.00e-55	208.00
IUUC-Bol-015214	Brassica oleracea	51.54	5.00e-61	227.00
IUUC-Bra-017491	Brassica rapa	52.42	1.00e-60	226.00
IUUC-Cel-018302	Caenorhabditis elegans	38.29	1.00e-32	132.00
IUUC-Cfa-020371	Canis familiaris	93.16	8.00e-102	362.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	43.26	4.00e-36	144.00
IUUC-Csa-023854	Chlorocebus sabaeus	96.52	1.00e-130	458.00
IUUC-Cin-025545	Ciona intestinalis	49.33	6.00e-65	239.00
IUUC-Cgl-026659	Colletotrichum gloeosporioides	34.20	4.00e-31	127.00
IUUC-Cne-026914	Cryptococcus neoformans	35.04	5.00e-29	120.00
IUUC-Cme-027216	Cyanidioschyzon merolae	36.32	5.00e-27	114.00
IUUC-Dre-028356	Danio rerio	73.91	4.00e-102	363.00
IUUC-Dse-031461	Dothistroma septosporum	39.66	4.00e-36	144.00
IUUC-Dme-032146	Drosophila melanogaster	50.66	5.00e-61	227.00
IUUC-Eca-033220	Equus caballus	96.09	2.00e-130	457.00
IUUC-Fca-036421	Felis catus	96.52	2.00e-131	461.00
IUUC-Fal-036773	Ficedula albicollis	84.79	8.00e-102	362.00
IUUC-Fox-037830	Fusarium oxysporum	35.50	9.00e-38	150.00
IUUC-Fso-038259	Fusarium solani	34.89	9.00e-35	142.00
IUUC-Gmo-039468	Gadus morhua	67.83	2.00e-82	298.00
IUUC-Ggr-039832	Gaeumannomyces graminis	35.81	6.00e-35	140.00
IUUC-Gga-041205	Gallus gallus	83.48	2.00e-107	381.00
IUUC-Gac-041629	Gasterosteus aculeatus	67.54	2.00e-86	311.00
IUUC-Gma-043057	Glycine max	49.34	2.00e-52	198.00
IUUC-Ggo-044533	Gorilla gorilla	96.10	4.00e-130	456.00
IUUC-Hsa-046754	Homo sapiens	96.52	2.00e-131	461.00
IUUC-Hvu-047176	Hordeum vulgare	40.61	5.00e-43	167.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	93.67	9.00e-86	308.00
IUUC-Kpa-049123	Komagataella pastoris	36.82	1.00e-30	126.00
IUUC-Lch-049685	Latimeria chalumnae	76.75	1.00e-106	378.00
IUUC-Lpe-051377	Leersia perrieri	45.32	8.00e-46	176.00
IUUC-Loc-051988	Lepisosteus oculatus	75.22	5.00e-103	366.00
IUUC-Lma-053316	Leptosphaeria maculans	38.96	8.00e-40	157.00
IUUC-Laf-053985	Loxodonta africana	95.67	1.00e-129	454.00
IUUC-Mcc-055888	Macaca mulatta	95.22	1.00e-127	447.00
IUUC-Mor-057271	Magnaporthe oryzae	36.24	4.00e-39	154.00
IUUC-Mpo-057343	Magnaporthe poae	32.19	7.00e-22	96.70
IUUC-Mtr-057713	Medicago truncatula	48.46	2.00e-53	202.00
IUUC-Mla-058942	Melampsora laricipopulina	45.37	3.00e-48	184.00
IUUC-Mga-059702	Meleagris gallopavo	84.51	5.00e-100	356.00
IUUC-Mvi-060249	Microbotryum violaceum	44.35	2.00e-42	165.00
IUUC-Mmr-061284	Microcebus murinus	96.20	3.00e-87	314.00
IUUC-Mdo-062639	Monodelphis domestica	77.90	7.00e-118	416.00
IUUC-Mmu-063299	Mus musculus	95.65	1.00e-130	458.00
IUUC-Mac-065075	Musa acuminata	44.98	2.00e-53	201.00
IUUC-Mpu-066769	Mustela putorius furo	96.52	2.00e-131	461.00
IUUC-Mlu-066937	Myotis lucifugus	94.35	1.00e-127	448.00
IUUC-Nfi-068320	Neosartorya fischeri	39.92	3.00e-43	168.00
IUUC-Ncr-068673	Neurospora crassa	36.80	4.00e-41	161.00
IUUC-Nle-069175	Nomascus leucogenys	96.23	1.00e-118	418.00
IUUC-Opr-070652	Ochotona princeps	94.78	1.00e-59	222.00
IUUC-Ont-072170	Oreochromis niloticus	69.74	2.00e-87	315.00
IUUC-Oan-073247	Ornithorhynchus anatinus	93.81	5.00e-59	218.00
IUUC-Ocu-074422	Oryctolagus cuniculus	96.52	5.00e-132	462.00
IUUC-Oba-075098	Oryza barthii	41.59	3.00e-49	187.00
IUUC-Obr-076041	Oryza brachyantha	44.74	1.00e-53	202.00
IUUC-Ogl-076980	Oryza glaberrima	45.18	4.00e-53	201.00
IUUC-Ogu-078978	Oryza glumaepatula	38.34	1.00e-46	179.00
IUUC-Oin-079285	Oryza indica	41.15	2.00e-48	185.00
IUUC-Olo-080671	Oryza longistaminata	41.59	2.00e-48	185.00
IUUC-Ome-081428	Oryza meridionalis	40.71	3.00e-47	181.00
IUUC-Oni-082406	Oryza nivara	41.59	3.00e-49	187.00
IUUC-Opu-083305	Oryza punctata	41.59	1.00e-47	182.00
IUUC-Oru-084969	Oryza rufipogon	41.59	3.00e-49	187.00
IUUC-Osa-085830	Oryza sativa	45.18	4.00e-53	201.00
IUUC-Ola-086893	Oryzias latipes	67.54	1.00e-83	302.00
IUUC-Olu-087858	Ostreococcus lucimarinus	44.74	8.00e-51	192.00
IUUC-Oga-088055	Otolemur garnettii	96.10	4.00e-130	456.00
IUUC-Oar-090319	Ovis aries	96.09	5.00e-131	459.00
IUUC-Pan-092714	Papio anubis	96.10	6.00e-130	456.00
IUUC-Psi-094036	Pelodiscus sinensis	83.87	1.00e-101	362.00
IUUC-Pma-094412	Petromyzon marinus	64.94	7.00e-55	205.00
IUUC-Pno-094997	Phaeosphaeria nodorum	35.43	5.00e-33	134.00
IUUC-Ppa-095519	Physcomitrella patens	50.67	4.00e-63	234.00
IUUC-Pfo-096182	Poecilia formosa	66.96	3.00e-86	311.00
IUUC-Pab-098216	Pongo abelii	94.44	6.00e-78	282.00
IUUC-Pop-099282	Populus trichocarpa	48.23	2.00e-51	195.00
IUUC-Ppe-101332	Prunus persica	48.23	9.00e-56	209.00
IUUC-Pgr-103430	Puccinia graminis	47.06	1.00e-50	192.00
IUUC-Ptt-103955	Puccinia triticina	48.71	2.00e-51	194.00
IUUC-Pte-104414	Pyrenophora teres	38.03	2.00e-37	149.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	33.61	4.00e-32	131.00
IUUC-Rno-105096	Rattus norvegicus	95.22	4.00e-130	456.00
IUUC-Sce-106412	Saccharomyces cerevisiae	32.38	5.00e-26	110.00
IUUC-Sha-106677	Sarcophilus harrisii	91.24	6.00e-117	412.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	30.00	6.00e-25	107.00
IUUC-Spo-108322	Schizosaccharomyces pombe	30.13	9.00e-24	103.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	38.03	3.00e-39	155.00
IUUC-Smo-109283	Selaginella moellendorffii	48.93	1.00e-52	199.00
IUUC-Sit-110163	Setaria italica	47.41	7.00e-55	207.00
IUUC-Sly-111832	Solanum lycopersicum	50.00	3.00e-55	207.00
IUUC-Stu-112526	Solanum tuberosum	50.00	1.00e-55	209.00
IUUC-Sbi-114545	Sorghum bicolor	46.72	9.00e-53	199.00
IUUC-Sre-114961	Sporisorium reilianum	42.49	2.00e-39	155.00
IUUC-Ssc-115255	Sus scrofa	94.81	3.00e-118	416.00
IUUC-Tgu-117003	Taeniopygia guttata	83.91	1.00e-106	379.00
IUUC-Tru-118330	Takifugu rubripes	62.84	1.00e-67	251.00
IUUC-Tsy-119488	Tarsius syrichta	92.98	8.00e-59	219.00
IUUC-Tni-120042	Tetraodon nigroviridis	62.50	2.00e-68	253.00
IUUC-Tca-120976	Theobroma cacao	46.90	2.00e-53	202.00
IUUC-Tre-122149	Trichoderma reesei	37.83	2.00e-41	161.00
IUUC-Tvi-122450	Trichoderma virens	37.39	6.00e-41	160.00
IUUC-Tae-122693	Triticum aestivum	44.78	2.00e-52	199.00
IUUC-Tur-126250	Triticum urartu	43.64	9.00e-52	196.00
IUUC-Tme-126961	Tuber melanosporum	36.60	4.00e-35	141.00
IUUC-Uma-129382	Ustilago maydis	41.38	5.00e-42	164.00
IUUC-Vda-129678	Verticillium dahliae	31.22	2.00e-29	122.00
IUUC-Vpa-130783	Vicugna pacos	93.91	4.00e-59	221.00
IUUC-Vvi-131661	Vitis vinifera	47.60	7.00e-56	210.00
IUUC-Xtr-132428	Xenopus tropicalis	72.61	1.00e-103	368.00
IUUC-Xma-134245	Xiphophorus maculatus	66.67	2.00e-86	311.00
IUUC-Yli-134570	Yarrowia lipolytica	35.47	1.00e-34	139.00
IUUC-Zma-134740	Zea mays	45.85	1.00e-54	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence