iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-043165

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CM000851

Gene Name

LOC100780392; GLYMA_18G058900

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA18G06620	GLYMA18G06620.1	GLYMA18G06620.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.40e-167	558.1	507	994

Active Site

Position(s)	Description	Evidence
688	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn 89
           YD Qi ++G++ q+kl+ +kv++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa a++ +np+ n
   Q: 507  YDAQISVFGQKLQKKLEDSKVFVVGSGALGCEFLKNLALMGVscgsqGKLTITDDDVIEKSNLSRQFLFRDWNIGQAKSTVAASAAAAINPSFN 600
           ********************************************************************************************** PP
   S: 90   veaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketp 180
           +ea ++++ +++e+++   F ++++vVv+aldn+ ar++v+++cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p
   Q: 601  IEALQNRVGTETENVFndtFWENLSVVVNALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFP 694
           **************999***************************************************************************** PP
   S: 181  naaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfec 262
            +++h+++wa            + +n +l++ ++ ++  ++   ++ ++ +++v + l +e+ e+fe++i++a+ +f+ ++ n +kql+  f+ 
   Q: 695  HNIDHCLTWArsefegllektpAEVNAYLSNPSEYTNAMKNAGDAQARDNLERVLECLDQEKCETFEDCITWARLKFEDYFVNRVKQLIYTFPE 788
           *********************9999********************************************************************* PP
   S: 263  divtkskspfwv..........................................................sfcsnaealqvpekvekdeevvka 298
           d  t+ ++pfw+                                                            ++ + ++ ++ek+++  +++ +
   Q: 789  DAATSTGAPFWSapkrfprplqfsasdlghlnfvssasilraetfgipipdwgknprkmaeavdrvivpdFQPKKDVKIVTDEKATSLSTASID 882
           *******************************999999999999999999999999999888888888885444444455566666666666666 PP
   S: 299  sap.lylllralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKv 387
           +a+ +  l+ +ler +++  +   ++ ++fekddd   ++d+++ +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv
   Q: 883  DAAvINDLVIKLERCRANlpPVFMMKPIQFEKDDDTnyHMDVIAGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKV 975
           6668666666666555542266778899******************************.*********************************** PP
   S: 388  vsg..kfeplknfflfdae 404
           ++g  k e ++n+f ++a+
   Q: 976  LDGghKVEDYRNTFANLAL 994
           ***999********99875 PP

Organism

Glycine max

Protein Sequence
(Fasta)

MLPTKRPCEG LVAEEETHNN NDNNNNSNNN NNNNNNNNNN NNSNNSSSSS SSLKKNRIAA 60
ARTADSTVKN YESTDQSFNN NNSNSGNASE GASDMALGES NQPDIDEDLH SRQLAVYGRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTGTCTCT GACTTTTATC TTTCGCTGCA CGCTTCTCAC TGTGTCCTCT TCTCTCTTTG 60
GGAGAGAAAA AATGGTAGTA GCAGCTGTCC TGTCCTCACT CGAAAACGAA ACCCTAGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

gmx:100780392

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002684	Amborella trichopoda	81.34	0.00e+00	1679.00
IUUC-Aly-005418	Arabidopsis lyrata	83.81	0.00e+00	1795.00
IUUC-Ath-006992	Arabidopsis thaliana	83.61	0.00e+00	1751.00
IUUC-Bdi-014843	Brachypodium distachyon	81.08	0.00e+00	1632.00
IUUC-Bol-015880	Brassica oleracea	84.49	0.00e+00	1804.00
IUUC-Bra-017252	Brassica rapa	84.49	0.00e+00	1803.00
IUUC-Cel-018260	Caenorhabditis elegans	38.97	0.00e+00	647.00
IUUC-Cho-024682	Choloepus hoffmanni	34.68	2.00e-98	353.00
IUUC-Cme-027290	Cyanidioschyzon merolae	38.86	0.00e+00	679.00
IUUC-Dme-032045	Drosophila melanogaster	44.08	0.00e+00	826.00
IUUC-Ete-033124	Echinops telfairi	38.76	5.00e-124	439.00
IUUC-Hvu-047418	Hordeum vulgare	81.29	0.00e+00	1648.00
IUUC-Opr-070715	Ochotona princeps	36.27	3.00e-147	516.00
IUUC-Oan-073268	Ornithorhynchus anatinus	40.55	1.00e-177	617.00
IUUC-Obr-076557	Oryza brachyantha	81.35	0.00e+00	1651.00
IUUC-Pma-094214	Petromyzon marinus	48.54	1.00e-35	142.00
IUUC-Ppa-095227	Physcomitrella patens	72.62	0.00e+00	1509.00
IUUC-Pab-097861	Pongo abelii	44.37	0.00e+00	832.00
IUUC-Pca-100347	Procavia capensis	41.59	0.00e+00	680.00
IUUC-Sha-107142	Sarcophilus harrisii	45.00	0.00e+00	863.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	44.76	0.00e+00	833.00
IUUC-Spo-108034	Schizosaccharomyces pombe	43.99	0.00e+00	820.00
IUUC-Smo-108912	Selaginella moellendorffii	73.70	0.00e+00	1535.00
IUUC-Sit-110281	Setaria italica	82.51	0.00e+00	1687.00
IUUC-Sbi-114089	Sorghum bicolor	82.21	0.00e+00	1691.00
IUUC-Tae-125113	Triticum aestivum	81.19	0.00e+00	1615.00
IUUC-Tur-126330	Triticum urartu	80.69	0.00e+00	1679.00
IUUC-Xtr-132026	Xenopus tropicalis	38.51	0.00e+00	636.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence