iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132518

Ensembl Protein ID

ENSXETP00000031368.2

UniProt Accession

F6Y6X0; F6Y6X0_XENTR

Genbank Protein ID

ENSXETP00000031368

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01078716

Gene Name

phf12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000014345.3	ENSXETT00000031368.2	ENSXETP00000031368.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.80e-08	34.6	268	314

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek.slveCekCrewfHpaClklsveeelpnsekwiCpk 50
           vC  C ++ +     l++C+ C   fH +Cl ++  + +p+   w+Cp+
   Q: 268  VCFTCSSSRSCRVaPLIQCDYCPLLFHMDCLDPP-LTAMPTGR-WMCPN 314
           666666666654379*******************.*******6.***95 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

NMETKTIVYD LDTSGGLMEQ IQALLAPPKS EEGEKKSKRP EKEPRRSGRA TNHDSCDSCK 60
EGGDLLCCDH CPAAFHLQCC NPPLSEEMLP PGEWMCHRCT IRRKKRERKK ELGQVNGLFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACGCACGTA AGCAGCTACG GAAGGGAGCC CTACCTCCAT AGCGACATAC CGACCTCCCG 60
CCTCTTCCTT CACAGCTGGG TTGGAGCGCT TTTTTCCCCA TTACGAATTG GGCCGCCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000253--FHA_dom
IPR031966--PHF12_MRG-bd
IPR008984--SMAD_FHA_domain
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50006--FHA_DOMAIN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD
PF16737--PHF12_MRG_bd

SMART

SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007848	Ashbya gossypii	52.00	5.00e-13	69.30
IUUC-Cin-025146	Ciona intestinalis	36.95	6.00e-39	156.00
IUUC-Dre-027802	Danio rerio	55.76	8.00e-163	567.00
IUUC-Dme-031758	Drosophila melanogaster	37.50	3.00e-65	243.00
IUUC-Fox-038014	Fusarium oxysporum	28.97	1.00e-08	55.80
IUUC-Gmo-038603	Gadus morhua	46.64	5.00e-170	591.00
IUUC-Lch-050540	Latimeria chalumnae	61.11	0.00e+00	1046.00
IUUC-Loc-052037	Lepisosteus oculatus	60.15	0.00e+00	1027.00
IUUC-Mvi-060276	Microbotryum violaceum	32.31	3.00e-11	63.90
IUUC-Ont-072294	Oreochromis niloticus	50.31	0.00e+00	652.00
IUUC-Oga-089177	Otolemur garnettii	66.73	0.00e+00	1164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence