iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
DNA & RNA Element
circBase
Protein-protein Interaction
iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.90e-08	33.9	236	311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlp.sGitydrssIekwl.asggktcP..vtrqplteedlvPnltlrrliqawceen 72
           +vp+e+lCpI   l+++  v++ +G +y + +Ie  + + ++++cP   +++ ++ ++++Pn+tlr+   aw+++ 
   Q: 236  KVPPELLCPICQSLFKEAIVTScCGNSYCADCIEARIlDPDNQKCPgaDCGKDISITSIIPNKTLRDAAAAWLSAT 311
           59****************99888***********87757788899955699*********************9876 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSSIHYKFRA ELDYKTLQFD GLHIRGEQLV REICAKENLK LELFELQLQN AHTKKTYSDD 60
ELIPRNSSII VQRFPRKDAA KVQKVQAGVN SGMVNQLDAT SSFLDPSSHI SSAEFENMDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAGTTTC GGAACGAGGG TTTTTAAATG TCGTCAATTC ACTACAAGTT CCGTGCGGAA 60
CTTGATTACA AGACACTGCA GTTTGACGGA CTGCATATTC GTGGCGAGCA ACTTGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR014891--DWNN_domain
IPR003613--Ubox_domain
IPR025829--Zn_knuckle_CX2CX3GHX4C
IPR001878--Znf_CCHC
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51282--DWNN
PS51698--U_BOX
PS50158--ZF_CCHC
PS50089--ZF_RING_2

Pfam

PF08783--DWNN
PF13696--zf-CCHC_2

SMART

SM01180--DWNN

Gene Ontology

GO:0005634--C:nucleus
GO:0003676--F:nucleic acid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000195	Aegilops tauschii	24.87	4.00e-15	75.50
IUUC-Aml-001655	Ailuropoda melanoleuca	35.82	4.00e-50	192.00
IUUC-Atr-002768	Amborella trichopoda	33.13	2.00e-12	66.60
IUUC-Apl-004100	Anas platyrhynchos	32.76	1.00e-32	135.00
IUUC-Aca-004345	Anolis carolinensis	37.13	1.00e-26	114.00
IUUC-Aly-006444	Arabidopsis lyrata	27.63	6.00e-25	108.00
IUUC-Ath-007648	Arabidopsis thaliana	27.18	1.00e-24	107.00
IUUC-Ago-007949	Ashbya gossypii	25.57	3.00e-19	88.20
IUUC-Acl-008118	Aspergillus clavatus	29.30	3.00e-11	62.40
IUUC-Afl-008408	Aspergillus flavus	29.14	6.00e-08	50.80
IUUC-Afu-008777	Aspergillus fumigatus	27.30	8.00e-19	87.40
IUUC-Ani-009426	Aspergillus nidulans	26.80	9.00e-22	97.40
IUUC-Ang-009735	Aspergillus niger	25.82	8.00e-15	74.30
IUUC-Aor-010213	Aspergillus oryzae	26.32	3.00e-17	82.00
IUUC-Ate-010474	Aspergillus terreus	27.35	4.00e-17	81.60
IUUC-Ame-010679	Astyanax mexicanus	35.21	8.00e-52	198.00
IUUC-Bgr-012229	Blumeria graminis	25.66	7.00e-20	90.90
IUUC-Bta-012672	Bos taurus	35.82	2.00e-50	193.00
IUUC-Bci-013880	Botrytis cinerea	28.11	3.00e-17	82.00
IUUC-Bdi-014276	Brachypodium distachyon	26.79	5.00e-18	85.50
IUUC-Bol-015602	Brassica oleracea	28.46	2.00e-27	116.00
IUUC-Bra-016670	Brassica rapa	28.46	2.00e-27	116.00
IUUC-Cja-018843	Callithrix jacchus	34.22	1.00e-38	154.00
IUUC-Cfa-021107	Canis familiaris	35.82	2.00e-50	194.00
IUUC-Cre-022712	Chlamydomonas reinhardtii	44.59	3.00e-10	58.50
IUUC-Csa-023397	Chlorocebus sabaeus	35.82	2.00e-50	194.00
IUUC-Cho-024327	Choloepus hoffmanni	35.93	3.00e-50	193.00
IUUC-Cin-025439	Ciona intestinalis	29.69	1.00e-17	82.00
IUUC-Csv-026162	Ciona savignyi	31.34	2.00e-22	97.80
IUUC-Cgl-026629	Colletotrichum gloeosporioides	24.09	3.00e-12	65.50
IUUC-Cne-026921	Cryptococcus neoformans	31.03	5.00e-17	81.30
IUUC-Cme-027244	Cyanidioschyzon merolae	35.71	1.00e-11	64.70
IUUC-Dre-028023	Danio rerio	37.01	2.00e-51	197.00
IUUC-Dno-029430	Dasypus novemcinctus	32.08	1.00e-43	171.00
IUUC-Dor-030406	Dipodomys ordii	33.85	3.00e-31	130.00
IUUC-Dse-031312	Dothistroma septosporum	28.57	5.00e-22	98.20
IUUC-Dme-032133	Drosophila melanogaster	31.66	2.00e-45	177.00
IUUC-Ete-032466	Echinops telfairi	37.08	3.00e-23	103.00
IUUC-Eca-033447	Equus caballus	35.58	1.00e-45	175.00
IUUC-Eeu-034677	Erinaceus europaeus	32.97	2.00e-33	137.00
IUUC-Fca-035439	Felis catus	35.82	3.00e-50	193.00
IUUC-Fal-037230	Ficedula albicollis	35.06	6.00e-49	189.00
IUUC-Fox-037976	Fusarium oxysporum	25.98	4.00e-18	85.10
IUUC-Fso-038202	Fusarium solani	25.00	4.00e-18	85.10
IUUC-Gmo-038618	Gadus morhua	35.44	6.00e-26	109.00
IUUC-Ggr-040035	Gaeumannomyces graminis	24.92	2.00e-17	82.80
IUUC-Gga-040908	Gallus gallus	35.04	7.00e-49	189.00
IUUC-Gac-041718	Gasterosteus aculeatus	34.17	4.00e-27	113.00
IUUC-Gma-044202	Glycine max	33.74	5.00e-20	92.00
IUUC-Ggo-044567	Gorilla gorilla	35.91	4.00e-49	189.00
IUUC-Hsa-046849	Homo sapiens	35.82	2.00e-50	193.00
IUUC-Hvu-047050	Hordeum vulgare	24.65	5.00e-15	75.10
IUUC-Itr-048832	Ictidomys tridecemlineatus	35.21	3.00e-50	193.00
IUUC-Kpa-049323	Komagataella pastoris	29.07	1.00e-25	109.00
IUUC-Lch-050524	Latimeria chalumnae	36.39	3.00e-51	196.00
IUUC-Lpe-050947	Leersia perrieri	24.15	1.00e-19	90.50
IUUC-Loc-052709	Lepisosteus oculatus	36.98	9.00e-48	185.00
IUUC-Lma-053186	Leptosphaeria maculans	25.72	2.00e-20	92.80
IUUC-Laf-054472	Loxodonta africana	35.21	5.00e-50	192.00
IUUC-Mcc-055743	Macaca mulatta	35.82	2.00e-50	193.00
IUUC-Meu-056399	Macropus eugenii	35.71	2.00e-27	117.00
IUUC-Mor-057073	Magnaporthe oryzae	25.16	2.00e-15	76.30
IUUC-Mpo-057378	Magnaporthe poae	26.99	8.00e-18	84.30
IUUC-Mtr-057707	Medicago truncatula	27.61	4.00e-10	58.90
IUUC-Mla-058840	Melampsora laricipopulina	33.82	4.00e-18	85.50
IUUC-Mga-060129	Meleagris gallopavo	32.64	1.00e-33	137.00
IUUC-Mvi-060424	Microbotryum violaceum	33.99	1.00e-17	84.00
IUUC-Mmr-061295	Microcebus murinus	37.09	2.00e-53	203.00
IUUC-Mdo-062295	Monodelphis domestica	30.41	1.00e-42	168.00
IUUC-Mmu-064009	Mus musculus	35.21	5.00e-51	196.00
IUUC-Mac-064709	Musa acuminata	32.52	4.00e-19	88.60
IUUC-Mpu-065875	Mustela putorius furo	35.82	2.00e-50	194.00
IUUC-Mlu-066941	Myotis lucifugus	35.52	1.00e-49	191.00
IUUC-Nfi-068518	Neosartorya fischeri	27.89	9.00e-19	87.40
IUUC-Ncr-068886	Neurospora crassa	25.71	2.00e-20	92.80
IUUC-Nle-069717	Nomascus leucogenys	35.82	3.00e-50	193.00
IUUC-Opr-070280	Ochotona princeps	34.39	6.00e-41	162.00
IUUC-Ont-071462	Oreochromis niloticus	34.50	4.00e-50	193.00
IUUC-Oan-073300	Ornithorhynchus anatinus	35.54	6.00e-35	142.00
IUUC-Ocu-074124	Oryctolagus cuniculus	35.50	2.00e-50	194.00
IUUC-Oba-075756	Oryza barthii	24.08	2.00e-18	86.30
IUUC-Obr-076580	Oryza brachyantha	33.73	6.00e-18	84.70
IUUC-Ogl-077759	Oryza glaberrima	25.59	1.00e-23	103.00
IUUC-Ogu-078657	Oryza glumaepatula	24.08	2.00e-18	87.00
IUUC-Oin-079481	Oryza indica	25.57	4.00e-18	85.90
IUUC-Olo-081062	Oryza longistaminata	33.73	9.00e-19	87.40
IUUC-Ome-081813	Oryza meridionalis	24.08	4.00e-18	85.50
IUUC-Oni-083007	Oryza nivara	24.08	4.00e-18	85.50
IUUC-Opu-083385	Oryza punctata	24.60	6.00e-18	85.10
IUUC-Oru-084861	Oryza rufipogon	24.08	4.00e-18	85.90
IUUC-Osa-085896	Oryza sativa	25.59	3.00e-24	104.00
IUUC-Ola-086693	Oryzias latipes	33.55	2.00e-46	179.00
IUUC-Olu-087631	Ostreococcus lucimarinus	41.33	2.00e-08	48.90
IUUC-Oga-088262	Otolemur garnettii	35.80	1.00e-50	194.00
IUUC-Oar-089658	Ovis aries	35.82	2.00e-50	194.00
IUUC-Ptr-091311	Pan troglodytes	35.99	8.00e-52	198.00
IUUC-Pan-091925	Papio anubis	35.80	8.00e-51	195.00
IUUC-Psi-093605	Pelodiscus sinensis	32.53	3.00e-32	133.00
IUUC-Pma-094163	Petromyzon marinus	34.05	4.00e-31	126.00
IUUC-Pno-094790	Phaeosphaeria nodorum	33.33	5.00e-14	71.20
IUUC-Ppa-095572	Physcomitrella patens	31.29	3.00e-11	62.40
IUUC-Pfo-096581	Poecilia formosa	33.82	8.00e-46	178.00
IUUC-Pab-098229	Pongo abelii	35.82	2.00e-50	194.00
IUUC-Pop-099598	Populus trichocarpa	34.76	1.00e-19	90.90
IUUC-Pca-100875	Procavia capensis	37.06	3.00e-16	80.50
IUUC-Ppe-101658	Prunus persica	32.52	4.00e-13	69.30
IUUC-Pva-102343	Pteropus vampyrus	34.73	2.00e-48	187.00
IUUC-Pgr-103275	Puccinia graminis	31.67	9.00e-12	64.70
IUUC-Ptt-104004	Puccinia triticina	27.52	3.00e-04	38.90
IUUC-Pte-104161	Pyrenophora teres	26.44	2.00e-15	76.30
IUUC-Pyt-104576	Pyrenophora triticirepentis	26.89	1.00e-16	80.10
IUUC-Rno-105264	Rattus norvegicus	35.21	7.00e-51	195.00
IUUC-Sce-106138	Saccharomyces cerevisiae	25.80	3.00e-22	98.20
IUUC-Sha-107497	Sarcophilus harrisii	34.88	2.00e-50	194.00
IUUC-Sja-107991	Schizosaccharomyces japonicus	29.57	8.00e-26	110.00
IUUC-Spo-108257	Schizosaccharomyces pombe	28.45	8.00e-26	110.00
IUUC-Ssl-108581	Sclerotinia sclerotiorum	26.88	2.00e-18	86.30
IUUC-Smo-108954	Selaginella moellendorffii	34.32	1.00e-19	89.70
IUUC-Sit-109920	Setaria italica	25.20	2.00e-23	103.00
IUUC-Sly-111616	Solanum lycopersicum	34.36	2.00e-19	89.70
IUUC-Stu-112014	Solanum tuberosum	27.18	4.00e-17	80.90
IUUC-Sar-113120	Sorex araneus	36.32	5.00e-32	132.00
IUUC-Sbi-113881	Sorghum bicolor	34.50	9.00e-20	91.30
IUUC-Sre-115127	Sporisorium reilianum	26.84	1.00e-25	110.00
IUUC-Ssc-116147	Sus scrofa	35.82	2.00e-50	194.00
IUUC-Tgu-117215	Taeniopygia guttata	32.64	1.00e-33	138.00
IUUC-Tru-118525	Takifugu rubripes	33.93	1.00e-44	172.00
IUUC-Tsy-119160	Tarsius syrichta	35.80	9.00e-51	195.00
IUUC-Tni-120277	Tetraodon nigroviridis	35.10	2.00e-26	110.00
IUUC-Tca-121727	Theobroma cacao	33.13	8.00e-13	67.80
IUUC-Tre-122181	Trichoderma reesei	25.71	6.00e-16	77.80
IUUC-Tvi-122316	Trichoderma virens	24.68	7.00e-16	77.40
IUUC-Tae-125622	Triticum aestivum	25.60	9.00e-17	81.30
IUUC-Tur-126827	Triticum urartu	33.14	1.00e-12	67.00
IUUC-Tme-126984	Tuber melanosporum	26.63	1.00e-22	100.00
IUUC-Tbe-127263	Tupaia belangeri	50.70	2.00e-15	77.80
IUUC-Ttr-128498	Tursiops truncatus	34.33	3.00e-48	186.00
IUUC-Uma-129457	Ustilago maydis	24.79	6.00e-26	111.00
IUUC-Vda-129986	Verticillium dahliae	24.40	8.00e-17	80.90
IUUC-Vpa-130795	Vicugna pacos	34.01	2.00e-28	120.00
IUUC-Vvi-131146	Vitis vinifera	33.13	1.00e-12	67.40
IUUC-Xtr-132789	Xenopus tropicalis	34.71	7.00e-50	192.00
IUUC-Xma-133011	Xiphophorus maculatus	33.24	6.00e-45	174.00
IUUC-Yli-134516	Yarrowia lipolytica	29.76	2.00e-16	79.00
IUUC-Zma-134699	Zea mays	26.32	1.00e-21	97.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence