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Tag Content
UUCD2 ID IUUC-Bta-013402
UUCD1 version UUC-BoT-00955
Ensembl Protein ID ENSBTAP00000003156.3
UniProt Accession Q3SZD4; WDR18_BOVIN
Genbank Protein ID AAI02947.1
Protein Name WD repeat-containing protein 18
Genbank Nucleotide ID BC102946
Gene Name WDR18
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000002434.3 ENSBTAT00000003156.3 ENSBTAP00000003156.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 9.10e-18 63.8 267 306
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH + vtcl+  +d   l+sGs+D t+++WD+ ++ +l++
   Q: 267  GHRNQVTCLSVsTDgSVLLSGSHDETVRLWDVQSQQCLRT 306
           8**********988899*******************9985 PP
   
Organism Bos taurus
Functional Description
(View)

Functional Description


     May play a role during development. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity).
 May play a role during development. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity).
Protein Sequence
(Fasta)
MAAPMEVAVC TDSAAQLWSC VVWELHSGAN LLTYRGGQAG PRGLALLNGE YLLAAQLGKN 60
YICAWELQRK DQLQQKIMCP GPVTCLTTSP NGLYVLAGIS ENIYLWEVST GNLLVILSRH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-013402|E3,WD_repeat|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAGGCAAGA TGGCGGCGCC CATGGAGGTA GCCGTGTGTA CGGACTCGGC GGCCCAGTTA 60
TGGAGCTGCG TTGTGTGGGA GCTGCACTCT GGCGCCAACT TGCTCACGTA CCGCGGAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-013402|E3,WD_repeat|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0217--Developmental protein
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR026987--Wdr18_C_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PF14077--WD40_alt
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0007275--P:multicellular organism development
KEGG bta:533356
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001040 Aegilops tauschii 31.71 2.00e-29 123.00
IUUC-Aml-001819 Ailuropoda melanoleuca 92.82 0.00e+00 777.00
IUUC-Atr-002808 Amborella trichopoda 34.33 5.00e-31 128.00
IUUC-Apl-004023 Anas platyrhynchos 57.23 9.00e-109 386.00
IUUC-Aca-004879 Anolis carolinensis 66.67 8.00e-58 215.00
IUUC-Aly-006061 Arabidopsis lyrata 31.29 1.00e-37 150.00
IUUC-Ath-007111 Arabidopsis thaliana 31.09 2.00e-35 143.00
IUUC-Ani-009132 Aspergillus nidulans 24.68 2.00e-15 77.00
IUUC-Ate-010249 Aspergillus terreus 25.22 4.00e-17 83.20
IUUC-Ame-010912 Astyanax mexicanus 63.34 3.00e-169 588.00
IUUC-Bgr-012242 Blumeria graminis 25.75 3.00e-13 69.70
IUUC-Bci-013791 Botrytis cinerea 25.35 7.00e-13 68.60
IUUC-Bdi-014455 Brachypodium distachyon 31.93 5.00e-32 131.00
IUUC-Bol-016342 Brassica oleracea 30.13 3.00e-32 132.00
IUUC-Bra-016967 Brassica rapa 30.87 3.00e-33 135.00
IUUC-Cja-019758 Callithrix jacchus 86.78 0.00e+00 691.00
IUUC-Cfa-020495 Canis familiaris 92.56 0.00e+00 673.00
IUUC-Cpo-021438 Cavia porcellus 88.64 4.00e-174 603.00
IUUC-Csa-023416 Chlorocebus sabaeus 90.05 0.00e+00 753.00
IUUC-Csv-025918 Ciona savignyi 34.18 6.00e-63 234.00
IUUC-Cne-026843 Cryptococcus neoformans 28.35 2.00e-18 86.70
IUUC-Dre-027560 Danio rerio 62.18 2.00e-167 581.00
IUUC-Dno-029315 Dasypus novemcinctus 88.84 0.00e+00 764.00
IUUC-Dor-030935 Dipodomys ordii 88.32 0.00e+00 771.00
IUUC-Dse-031492 Dothistroma septosporum 23.69 6.00e-19 89.00
IUUC-Dme-032059 Drosophila melanogaster 35.07 3.00e-56 213.00
IUUC-Fca-036068 Felis catus 87.76 0.00e+00 731.00
IUUC-Fal-037467 Ficedula albicollis 71.97 3.00e-164 571.00
IUUC-Fox-037903 Fusarium oxysporum 25.75 9.00e-18 84.70
IUUC-Gmo-039323 Gadus morhua 53.97 9.00e-118 416.00
IUUC-Ggr-040050 Gaeumannomyces graminis 26.99 9.00e-11 61.60
IUUC-Gga-040563 Gallus gallus 72.04 5.00e-154 537.00
IUUC-Gac-042641 Gasterosteus aculeatus 60.42 3.00e-154 538.00
IUUC-Gma-044265 Glycine max 29.20 2.00e-41 162.00
IUUC-Ggo-045137 Gorilla gorilla 90.28 0.00e+00 728.00
IUUC-Hsa-046335 Homo sapiens 90.05 0.00e+00 727.00
IUUC-Hvu-047685 Hordeum vulgare 32.93 5.00e-33 135.00
IUUC-Itr-048032 Ictidomys tridecemlineatus 88.66 0.00e+00 801.00
IUUC-Kpa-049129 Komagataella pastoris 31.00 6.00e-30 125.00
IUUC-Lch-049532 Latimeria chalumnae 66.36 7.00e-180 623.00
IUUC-Lpe-051321 Leersia perrieri 31.10 5.00e-29 121.00
IUUC-Loc-052471 Lepisosteus oculatus 61.43 2.00e-159 555.00
IUUC-Lma-053091 Leptosphaeria maculans 26.33 3.00e-24 106.00
IUUC-Laf-054331 Loxodonta africana 88.43 0.00e+00 712.00
IUUC-Mcc-055803 Macaca mulatta 90.05 0.00e+00 753.00
IUUC-Meu-056090 Macropus eugenii 76.16 0.00e+00 698.00
IUUC-Mor-057160 Magnaporthe oryzae 25.19 9.00e-16 78.20
IUUC-Mtr-058800 Medicago truncatula 33.82 4.00e-42 165.00
IUUC-Mla-058943 Melampsora laricipopulina 38.56 2.00e-25 110.00
IUUC-Mga-059282 Meleagris gallopavo 64.81 2.00e-140 491.00
IUUC-Mvi-060315 Microbotryum violaceum 37.43 5.00e-28 119.00
IUUC-Mmr-061127 Microcebus murinus 91.44 0.00e+00 776.00
IUUC-Mdo-062350 Monodelphis domestica 75.93 0.00e+00 693.00
IUUC-Mmu-063706 Mus musculus 85.88 0.00e+00 746.00
IUUC-Mac-065554 Musa acuminata 29.31 2.00e-27 116.00
IUUC-Mpu-066711 Mustela putorius furo 91.67 0.00e+00 833.00
IUUC-Mlu-068121 Myotis lucifugus 90.06 6.00e-180 622.00
IUUC-Ncr-068914 Neurospora crassa 27.24 5.00e-16 79.00
IUUC-Nle-069518 Nomascus leucogenys 89.14 0.00e+00 677.00
IUUC-Ont-071435 Oreochromis niloticus 61.57 1.00e-155 542.00
IUUC-Oan-073532 Ornithorhynchus anatinus 71.15 5.00e-42 162.00
IUUC-Oba-075873 Oryza barthii 31.40 3.00e-39 155.00
IUUC-Obr-076097 Oryza brachyantha 28.11 2.00e-27 117.00
IUUC-Ogl-077840 Oryza glaberrima 31.40 3.00e-39 155.00
IUUC-Ogu-077988 Oryza glumaepatula 31.40 3.00e-39 155.00
IUUC-Oin-079237 Oryza indica 33.03 6.00e-26 111.00
IUUC-Olo-080415 Oryza longistaminata 30.96 1.00e-31 131.00
IUUC-Ome-081952 Oryza meridionalis 31.10 6.00e-38 151.00
IUUC-Oni-082300 Oryza nivara 31.40 3.00e-39 155.00
IUUC-Opu-083436 Oryza punctata 33.33 4.00e-24 105.00
IUUC-Oru-085164 Oryza rufipogon 31.10 2.00e-39 156.00
IUUC-Osa-086129 Oryza sativa 31.40 2.00e-39 156.00
IUUC-Ola-086571 Oryzias latipes 57.64 2.00e-143 502.00
IUUC-Oga-088561 Otolemur garnettii 91.44 0.00e+00 791.00
IUUC-Oar-090131 Ovis aries 87.76 0.00e+00 681.00
IUUC-Ptr-091301 Pan troglodytes 72.08 3.00e-163 567.00
IUUC-Pan-092810 Papio anubis 89.81 0.00e+00 751.00
IUUC-Psi-093091 Pelodiscus sinensis 63.59 1.00e-127 449.00
IUUC-Pno-095047 Phaeosphaeria nodorum 24.08 1.00e-18 88.20
IUUC-Ppa-095317 Physcomitrella patens 40.23 2.00e-35 143.00
IUUC-Pfo-096996 Poecilia formosa 59.16 1.00e-145 509.00
IUUC-Pab-097747 Pongo abelii 90.62 0.00e+00 728.00
IUUC-Pop-099609 Populus trichocarpa 34.43 8.00e-44 171.00
IUUC-Pca-100972 Procavia capensis 83.33 0.00e+00 631.00
IUUC-Ppe-101904 Prunus persica 34.04 7.00e-45 174.00
IUUC-Pva-102700 Pteropus vampyrus 78.25 5.00e-164 570.00
IUUC-Pgr-103616 Puccinia graminis 36.36 9.00e-23 101.00
IUUC-Ptt-103954 Puccinia triticina 36.91 2.00e-21 97.10
IUUC-Pte-104120 Pyrenophora teres 26.00 1.00e-24 108.00
IUUC-Pyt-104558 Pyrenophora triticirepentis 26.67 3.00e-25 110.00
IUUC-Rno-104933 Rattus norvegicus 84.49 0.00e+00 736.00
IUUC-Sce-106403 Saccharomyces cerevisiae 22.97 8.00e-13 68.60
IUUC-Sha-107636 Sarcophilus harrisii 76.62 0.00e+00 698.00
IUUC-Sja-107783 Schizosaccharomyces japonicus 34.29 6.00e-36 145.00
IUUC-Spo-108192 Schizosaccharomyces pombe 27.67 2.00e-24 106.00
IUUC-Ssl-108384 Sclerotinia sclerotiorum 27.18 4.00e-18 85.90
IUUC-Smo-109498 Selaginella moellendorffii 37.80 3.00e-40 159.00
IUUC-Sit-110770 Setaria italica 33.87 9.00e-38 150.00
IUUC-Sly-111453 Solanum lycopersicum 33.83 9.00e-44 171.00
IUUC-Stu-112384 Solanum tuberosum 33.53 1.00e-43 171.00
IUUC-Sbi-113952 Sorghum bicolor 32.80 9.00e-37 147.00
IUUC-Sre-115223 Sporisorium reilianum 32.66 1.00e-24 108.00
IUUC-Ssc-115627 Sus scrofa 95.14 0.00e+00 792.00
IUUC-Tgu-117404 Taeniopygia guttata 72.39 1.00e-157 548.00
IUUC-Tru-117629 Takifugu rubripes 60.20 5.00e-133 467.00
IUUC-Tni-119839 Tetraodon nigroviridis 58.06 5.00e-132 464.00
IUUC-Tca-121766 Theobroma cacao 34.52 1.00e-44 174.00
IUUC-Tae-125634 Triticum aestivum 33.03 3.00e-33 136.00
IUUC-Tur-126673 Triticum urartu 29.68 5.00e-24 105.00
IUUC-Tme-127070 Tuber melanosporum 25.54 5.00e-19 89.00
IUUC-Tbe-127452 Tupaia belangeri 84.55 5.00e-113 401.00
IUUC-Ttr-128735 Tursiops truncatus 91.44 0.00e+00 745.00
IUUC-Uma-129521 Ustilago maydis 33.67 7.00e-24 105.00
IUUC-Vvi-130872 Vitis vinifera 33.73 3.00e-41 162.00
IUUC-Xtr-131838 Xenopus tropicalis 64.02 1.00e-144 506.00
IUUC-Xma-134106 Xiphophorus maculatus 65.59 1.00e-117 416.00
IUUC-Yli-134551 Yarrowia lipolytica 26.62 4.00e-22 99.00
IUUC-Zma-134703 Zea mays 33.55 3.00e-36 145.00
Created Date 25-Jun-2017

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