iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089259

Ensembl Protein ID

ENSOARP00000007586.1

UniProt Accession

W5PAX5; W5PAX5_SHEEP

Genbank Protein ID

ENSOARP00000007586

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01034553

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000007073.1	ENSOART00000007699.1	ENSOARP00000007586.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.10e-29	99.6	98	130

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlr 31
           H+ sv  +++  +d +++ s+s D+t+kvWD+ 
   Q: 98   HKYSVETVQWypHDtGMFTSSSFDKTLKVWDTN 130
           8999*******9778****************75 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MLGFLSARQA GLEDPLRLRR AESTRRVLGL ELNKDRDVER IHCSGVNTLD IEPVEGRYML 60
SGGSDGVIVL YDLENSSRQP YYTCKAVCSV GRSHPDVHKY SVETVQWYPH DTGMFTSSSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTAGGGT TCTTGTCGGC TCGACAGGCG GGTTTAGAAG ACCCTCTTCG CCTCCGGAGA 60
GCAGAGTCCA CACGGAGGTA AAGAAAGCCT TACTTTTTAG TCTAACGTGC TAGTTAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

KEGG

oas:101108254

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	32.10	5.00e-38	153.00
IUUC-Aml-002201	Ailuropoda melanoleuca	93.95	0.00e+00	777.00
IUUC-Atr-002784	Amborella trichopoda	37.02	2.00e-40	159.00
IUUC-Apl-003202	Anas platyrhynchos	81.05	0.00e+00	654.00
IUUC-Aca-004708	Anolis carolinensis	82.47	2.00e-178	617.00
IUUC-Aly-006144	Arabidopsis lyrata	39.61	2.00e-43	170.00
IUUC-Ath-006673	Arabidopsis thaliana	40.67	7.00e-45	174.00
IUUC-Acl-008195	Aspergillus clavatus	39.02	8.00e-43	167.00
IUUC-Afl-008406	Aspergillus flavus	37.25	3.00e-38	152.00
IUUC-Afu-008759	Aspergillus fumigatus	36.23	1.00e-39	157.00
IUUC-Ani-009380	Aspergillus nidulans	35.76	4.00e-41	162.00
IUUC-Ang-009820	Aspergillus niger	37.55	1.00e-38	154.00
IUUC-Aor-010092	Aspergillus oryzae	37.88	2.00e-43	169.00
IUUC-Ate-010491	Aspergillus terreus	37.72	1.00e-44	174.00
IUUC-Bta-012825	Bos taurus	99.24	0.00e+00	823.00
IUUC-Bci-013856	Botrytis cinerea	32.68	2.00e-53	202.00
IUUC-Bdi-014899	Brachypodium distachyon	34.41	2.00e-65	243.00
IUUC-Bol-015337	Brassica oleracea	31.25	4.00e-51	195.00
IUUC-Bra-018089	Brassica rapa	37.93	4.00e-44	172.00
IUUC-Cja-018725	Callithrix jacchus	93.20	0.00e+00	772.00
IUUC-Cfa-021162	Canis familiaris	94.96	0.00e+00	780.00
IUUC-Cpo-022190	Cavia porcellus	92.95	0.00e+00	773.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	37.14	2.00e-39	157.00
IUUC-Csa-023610	Chlorocebus sabaeus	94.46	0.00e+00	783.00
IUUC-Cho-024689	Choloepus hoffmanni	92.45	0.00e+00	710.00
IUUC-Cin-025324	Ciona intestinalis	39.62	7.00e-80	290.00
IUUC-Csv-026059	Ciona savignyi	38.44	3.00e-74	272.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	34.81	1.00e-40	160.00
IUUC-Cme-027182	Cyanidioschyzon merolae	28.66	2.00e-12	68.20
IUUC-Dre-028696	Danio rerio	72.64	6.00e-177	613.00
IUUC-Dno-029102	Dasypus novemcinctus	94.71	0.00e+00	782.00
IUUC-Dor-030361	Dipodomys ordii	75.82	4.00e-174	603.00
IUUC-Dse-031167	Dothistroma septosporum	30.20	8.00e-46	177.00
IUUC-Ete-032856	Echinops telfairi	76.07	5.00e-175	606.00
IUUC-Eca-033611	Equus caballus	95.58	0.00e+00	674.00
IUUC-Eeu-034583	Erinaceus europaeus	72.04	2.00e-160	558.00
IUUC-Fca-036481	Felis catus	94.46	0.00e+00	779.00
IUUC-Fal-037327	Ficedula albicollis	79.71	3.00e-165	573.00
IUUC-Fox-037684	Fusarium oxysporum	33.45	5.00e-44	172.00
IUUC-Fso-038306	Fusarium solani	34.31	5.00e-55	208.00
IUUC-Gmo-039043	Gadus morhua	69.44	1.00e-166	579.00
IUUC-Ggr-039783	Gaeumannomyces graminis	32.28	3.00e-39	156.00
IUUC-Gga-041085	Gallus gallus	86.78	0.00e+00	638.00
IUUC-Gac-042328	Gasterosteus aculeatus	67.99	8.00e-160	556.00
IUUC-Gma-042916	Glycine max	31.70	2.00e-56	213.00
IUUC-Ggo-045627	Gorilla gorilla	85.82	0.00e+00	706.00
IUUC-Hsa-046028	Homo sapiens	94.46	0.00e+00	783.00
IUUC-Hvu-047678	Hordeum vulgare	32.80	2.00e-35	142.00
IUUC-Itr-048648	Ictidomys tridecemlineatus	94.21	0.00e+00	780.00
IUUC-Kpa-049386	Komagataella pastoris	31.23	1.00e-42	167.00
IUUC-Lch-050590	Latimeria chalumnae	80.46	2.00e-162	564.00
IUUC-Lpe-051725	Leersia perrieri	33.76	9.00e-37	147.00
IUUC-Loc-051788	Lepisosteus oculatus	75.77	2.00e-180	624.00
IUUC-Lma-053082	Leptosphaeria maculans	34.27	4.00e-54	205.00
IUUC-Laf-053809	Loxodonta africana	94.96	0.00e+00	794.00
IUUC-Mcc-054998	Macaca mulatta	95.02	6.00e-162	563.00
IUUC-Meu-055929	Macropus eugenii	77.89	0.00e+00	637.00
IUUC-Mor-057003	Magnaporthe oryzae	33.63	3.00e-48	186.00
IUUC-Mtr-057921	Medicago truncatula	31.70	7.00e-57	214.00
IUUC-Mga-059449	Meleagris gallopavo	66.28	5.00e-125	440.00
IUUC-Mmr-061609	Microcebus murinus	91.33	0.00e+00	730.00
IUUC-Mdo-062564	Monodelphis domestica	86.18	0.00e+00	723.00
IUUC-Mmu-063904	Mus musculus	89.67	0.00e+00	747.00
IUUC-Mac-064716	Musa acuminata	38.39	8.00e-41	161.00
IUUC-Mpu-066617	Mustela putorius furo	94.96	0.00e+00	782.00
IUUC-Mlu-067054	Myotis lucifugus	93.20	0.00e+00	771.00
IUUC-Nfi-068467	Neosartorya fischeri	36.90	1.00e-33	137.00
IUUC-Nle-069731	Nomascus leucogenys	94.46	0.00e+00	783.00
IUUC-Opr-070297	Ochotona princeps	68.62	8.00e-88	317.00
IUUC-Ont-072558	Oreochromis niloticus	70.82	6.00e-165	573.00
IUUC-Oan-072864	Ornithorhynchus anatinus	89.47	1.00e-27	113.00
IUUC-Ocu-074415	Oryctolagus cuniculus	94.21	0.00e+00	783.00
IUUC-Oba-075759	Oryza barthii	41.58	6.00e-43	168.00
IUUC-Obr-076387	Oryza brachyantha	29.71	4.00e-45	175.00
IUUC-Ogl-077924	Oryza glaberrima	40.15	5.00e-18	84.30
IUUC-Ogu-078186	Oryza glumaepatula	34.88	1.00e-62	233.00
IUUC-Oin-079389	Oryza indica	34.18	1.00e-46	179.00
IUUC-Olo-080916	Oryza longistaminata	28.92	4.00e-17	80.90
IUUC-Ome-081471	Oryza meridionalis	40.53	4.00e-40	159.00
IUUC-Oni-082449	Oryza nivara	41.05	6.00e-40	158.00
IUUC-Opu-083210	Oryza punctata	30.31	8.00e-53	201.00
IUUC-Oru-085159	Oryza rufipogon	41.58	4.00e-43	169.00
IUUC-Osa-085926	Oryza sativa	41.89	4.00e-33	134.00
IUUC-Ola-087084	Oryzias latipes	69.27	3.00e-168	584.00
IUUC-Olu-087853	Ostreococcus lucimarinus	29.37	1.00e-38	153.00
IUUC-Oga-089008	Otolemur garnettii	92.73	0.00e+00	776.00
IUUC-Ptr-091112	Pan troglodytes	93.65	0.00e+00	771.00
IUUC-Pan-092303	Papio anubis	92.25	1.00e-67	247.00
IUUC-Psi-093050	Pelodiscus sinensis	83.46	0.00e+00	696.00
IUUC-Pma-094259	Petromyzon marinus	57.92	1.00e-130	459.00
IUUC-Pno-094798	Phaeosphaeria nodorum	31.89	1.00e-51	197.00
IUUC-Ppa-095477	Physcomitrella patens	31.37	5.00e-56	211.00
IUUC-Pfo-096855	Poecilia formosa	67.91	4.00e-164	570.00
IUUC-Pab-098096	Pongo abelii	93.70	0.00e+00	776.00
IUUC-Pop-098800	Populus trichocarpa	36.84	2.00e-45	176.00
IUUC-Pca-100187	Procavia capensis	95.63	2.00e-116	412.00
IUUC-Ppe-101759	Prunus persica	38.22	1.00e-44	173.00
IUUC-Pva-102438	Pteropus vampyrus	80.49	1.00e-93	336.00
IUUC-Pte-104197	Pyrenophora teres	33.05	5.00e-49	188.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	33.33	2.00e-48	186.00
IUUC-Rno-106087	Rattus norvegicus	90.93	0.00e+00	764.00
IUUC-Sce-106276	Saccharomyces cerevisiae	27.32	2.00e-12	67.00
IUUC-Sha-106831	Sarcophilus harrisii	82.91	0.00e+00	694.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	33.33	1.00e-55	210.00
IUUC-Spo-108294	Schizosaccharomyces pombe	35.07	4.00e-64	238.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	32.95	7.00e-52	197.00
IUUC-Smo-109008	Selaginella moellendorffii	40.05	4.00e-74	271.00
IUUC-Sit-110300	Setaria italica	31.58	3.00e-54	205.00
IUUC-Sly-111441	Solanum lycopersicum	30.35	1.00e-47	183.00
IUUC-Stu-111995	Solanum tuberosum	30.66	8.00e-48	184.00
IUUC-Sar-113196	Sorex araneus	83.27	4.00e-125	441.00
IUUC-Sbi-113790	Sorghum bicolor	40.98	5.00e-43	168.00
IUUC-Ssc-115609	Sus scrofa	95.97	0.00e+00	796.00
IUUC-Tgu-116927	Taeniopygia guttata	80.70	0.00e+00	660.00
IUUC-Tru-118164	Takifugu rubripes	69.73	3.00e-171	594.00
IUUC-Tsy-119151	Tarsius syrichta	88.41	0.00e+00	728.00
IUUC-Tni-120896	Tetraodon nigroviridis	68.91	1.00e-161	562.00
IUUC-Tca-121592	Theobroma cacao	28.25	6.00e-46	178.00
IUUC-Tre-122023	Trichoderma reesei	35.15	6.00e-50	191.00
IUUC-Tvi-122507	Trichoderma virens	36.99	1.00e-51	197.00
IUUC-Tae-125730	Triticum aestivum	31.13	5.00e-53	201.00
IUUC-Tur-126092	Triticum urartu	31.27	9.00e-36	144.00
IUUC-Tbe-127422	Tupaia belangeri	70.62	3.00e-147	514.00
IUUC-Ttr-129097	Tursiops truncatus	93.20	0.00e+00	770.00
IUUC-Vda-130014	Verticillium dahliae	36.05	8.00e-50	191.00
IUUC-Vpa-130782	Vicugna pacos	95.47	0.00e+00	794.00
IUUC-Vvi-131494	Vitis vinifera	27.67	7.00e-47	181.00
IUUC-Xtr-132165	Xenopus tropicalis	77.84	7.00e-180	622.00
IUUC-Xma-133205	Xiphophorus maculatus	68.58	2.00e-167	581.00
IUUC-Yli-134614	Yarrowia lipolytica	33.33	6.00e-57	214.00
IUUC-Zma-135861	Zea mays	34.96	3.00e-60	226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence