iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049620

Ensembl Protein ID

ENSLACP00000013988.2

UniProt Accession

H3AWG7; H3AWG7_LATCH

Genbank Protein ID

ENSLACP00000013988

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36

Genbank Nucleotide ID

AFYH01139778

Gene Name

EIF3I; EIF3S2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000012315.2	ENSLACT00000014087.2	ENSLACP00000013988.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-20	70.4	50	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
           gHt+ v+c+  ++ d +++++Gs D+++++WD  tg++l
   Q: 50   GHTGAVWCVdvDW-DtRHVLTGSADNSCRLWDCETGKQL 87
           8*******63377.559******************9986 PP

Organism

Latimeria chalumnae

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MKPILLQGHE RSITQIKYNR EGDLLFSVAK DPTVNVWYSV NGERLGTYGG HTGAVWCVDV 60
DWDTRHVLTG SADNSCRLWD CETGKQLALF KTNSAVRTCG FDFGGNIIMF STDKQMGYQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAGTTACTC AATTCATTCT CATTAGTAAT TGTTTTCTTT CAAACCATCA TGTTAATTAC 60
CTTTAATTTT TTTCACTACT TTAAATTTCT AATTTTTCTA CAGTCTAACT CGCTTTAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0001889--P:liver development
GO:0006446--P:regulation of translational initiation
GO:0002040--P:sprouting angiogenesis

KEGG

lcm:102360587

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	56.25	1.00e-33	137.00
IUUC-Aml-001321	Ailuropoda melanoleuca	86.20	4.00e-159	553.00
IUUC-Atr-002468	Amborella trichopoda	49.40	1.00e-42	166.00
IUUC-Apl-003841	Anas platyrhynchos	87.21	5.00e-162	563.00
IUUC-Aca-005123	Anolis carolinensis	86.58	2.00e-161	561.00
IUUC-Aly-005473	Arabidopsis lyrata	44.88	5.00e-76	277.00
IUUC-Ath-007094	Arabidopsis thaliana	45.87	3.00e-78	285.00
IUUC-Ago-008000	Ashbya gossypii	42.90	3.00e-70	258.00
IUUC-Acl-008098	Aspergillus clavatus	52.13	4.00e-89	321.00
IUUC-Afl-008494	Aspergillus flavus	50.67	2.00e-87	315.00
IUUC-Afu-009080	Aspergillus fumigatus	51.15	1.00e-88	319.00
IUUC-Ani-009230	Aspergillus nidulans	52.49	3.00e-89	321.00
IUUC-Aor-010114	Aspergillus oryzae	50.67	2.00e-87	315.00
IUUC-Ate-010285	Aspergillus terreus	52.16	2.00e-90	325.00
IUUC-Ame-011534	Astyanax mexicanus	82.33	7.00e-155	539.00
IUUC-Bgr-012121	Blumeria graminis	48.84	2.00e-83	302.00
IUUC-Bta-013143	Bos taurus	86.24	1.00e-159	555.00
IUUC-Bci-013950	Botrytis cinerea	52.82	1.00e-90	326.00
IUUC-Bdi-015019	Brachypodium distachyon	46.51	6.00e-79	287.00
IUUC-Bol-015709	Brassica oleracea	45.57	1.00e-74	273.00
IUUC-Bra-017760	Brassica rapa	45.57	5.00e-75	275.00
IUUC-Cel-018226	Caenorhabditis elegans	43.14	4.00e-74	271.00
IUUC-Cja-019741	Callithrix jacchus	86.58	2.00e-160	558.00
IUUC-Cfa-021204	Canis familiaris	86.20	3.00e-159	553.00
IUUC-Cpo-021661	Cavia porcellus	86.53	1.00e-159	555.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	43.29	1.00e-74	273.00
IUUC-Csa-024038	Chlorocebus sabaeus	86.58	2.00e-160	558.00
IUUC-Cin-025597	Ciona intestinalis	59.73	3.00e-107	381.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	50.17	8.00e-84	303.00
IUUC-Cne-026838	Cryptococcus neoformans	49.35	1.00e-85	309.00
IUUC-Cme-027304	Cyanidioschyzon merolae	44.33	3.00e-72	265.00
IUUC-Dre-028567	Danio rerio	84.56	4.00e-159	553.00
IUUC-Dno-029171	Dasypus novemcinctus	85.86	1.00e-158	552.00
IUUC-Dor-030257	Dipodomys ordii	75.00	5.00e-76	277.00
IUUC-Dse-031191	Dothistroma septosporum	48.53	2.00e-79	288.00
IUUC-Dme-031879	Drosophila melanogaster	60.33	2.00e-110	391.00
IUUC-Ete-032336	Echinops telfairi	83.18	1.00e-108	384.00
IUUC-Eca-033259	Equus caballus	86.53	1.00e-159	555.00
IUUC-Eeu-035153	Erinaceus europaeus	81.32	4.00e-39	155.00
IUUC-Fca-036489	Felis catus	86.53	1.00e-159	555.00
IUUC-Fal-037485	Ficedula albicollis	87.88	6.00e-163	566.00
IUUC-Fox-037860	Fusarium oxysporum	48.50	5.00e-83	300.00
IUUC-Fso-038188	Fusarium solani	49.50	6.00e-82	297.00
IUUC-Gmo-039311	Gadus morhua	82.49	4.00e-156	543.00
IUUC-Ggr-040045	Gaeumannomyces graminis	50.50	3.00e-87	315.00
IUUC-Gga-040645	Gallus gallus	84.97	1.00e-160	558.00
IUUC-Gac-042086	Gasterosteus aculeatus	83.56	5.00e-155	540.00
IUUC-Gma-043246	Glycine max	46.18	3.00e-78	285.00
IUUC-Ggo-045578	Gorilla gorilla	86.58	2.00e-160	558.00
IUUC-Hsa-046734	Homo sapiens	86.58	2.00e-160	558.00
IUUC-Hvu-047553	Hordeum vulgare	45.85	5.00e-78	284.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	86.20	2.00e-159	554.00
IUUC-Kpa-049325	Komagataella pastoris	43.48	1.00e-73	270.00
IUUC-Lpe-051338	Leersia perrieri	45.18	7.00e-78	283.00
IUUC-Loc-052094	Lepisosteus oculatus	79.12	2.00e-144	504.00
IUUC-Lma-053047	Leptosphaeria maculans	48.50	9.00e-82	296.00
IUUC-Laf-053801	Loxodonta africana	85.91	1.00e-155	541.00
IUUC-Mcc-055498	Macaca mulatta	76.17	1.00e-129	455.00
IUUC-Meu-056729	Macropus eugenii	78.60	2.00e-142	498.00
IUUC-Mor-057025	Magnaporthe oryzae	49.83	4.00e-84	304.00
IUUC-Mpo-057511	Magnaporthe poae	51.50	2.00e-87	315.00
IUUC-Mtr-058051	Medicago truncatula	46.18	4.00e-78	284.00
IUUC-Mla-059061	Melampsora laricipopulina	46.00	3.00e-76	278.00
IUUC-Mga-059229	Meleagris gallopavo	86.29	1.00e-159	555.00
IUUC-Mvi-060399	Microbotryum violaceum	46.30	3.00e-74	271.00
IUUC-Mmr-060764	Microcebus murinus	86.58	2.00e-160	558.00
IUUC-Mdo-062088	Monodelphis domestica	85.91	2.00e-159	554.00
IUUC-Mmu-064304	Mus musculus	85.91	1.00e-159	555.00
IUUC-Mac-065520	Musa acuminata	48.82	5.00e-80	290.00
IUUC-Mpu-066340	Mustela putorius furo	86.53	1.00e-159	555.00
IUUC-Mlu-067111	Myotis lucifugus	86.20	2.00e-159	554.00
IUUC-Nfi-068478	Neosartorya fischeri	51.80	2.00e-88	318.00
IUUC-Ncr-068820	Neurospora crassa	48.84	5.00e-83	300.00
IUUC-Nle-069903	Nomascus leucogenys	86.53	4.00e-160	556.00
IUUC-Opr-070221	Ochotona princeps	83.56	5.00e-154	536.00
IUUC-Ont-071765	Oreochromis niloticus	84.23	5.00e-158	550.00
IUUC-Oan-073660	Ornithorhynchus anatinus	85.34	3.00e-141	494.00
IUUC-Ocu-074039	Oryctolagus cuniculus	86.53	8.00e-160	555.00
IUUC-Oba-075395	Oryza barthii	38.87	8.00e-62	230.00
IUUC-Obr-076334	Oryza brachyantha	42.86	5.00e-71	260.00
IUUC-Ogl-077751	Oryza glaberrima	45.51	2.00e-78	285.00
IUUC-Ogu-078207	Oryza glumaepatula	45.51	2.00e-78	285.00
IUUC-Oin-079878	Oryza indica	45.85	8.00e-79	286.00
IUUC-Olo-080677	Oryza longistaminata	38.59	2.00e-69	256.00
IUUC-Ome-081228	Oryza meridionalis	34.57	1.00e-36	146.00
IUUC-Oni-082411	Oryza nivara	39.67	3.00e-61	228.00
IUUC-Opu-083136	Oryza punctata	45.85	7.00e-79	286.00
IUUC-Oru-084916	Oryza rufipogon	45.16	1.00e-76	279.00
IUUC-Osa-085454	Oryza sativa	45.85	8.00e-79	286.00
IUUC-Ola-087053	Oryzias latipes	84.56	5.00e-158	550.00
IUUC-Olu-087602	Ostreococcus lucimarinus	46.82	1.00e-80	292.00
IUUC-Oga-088154	Otolemur garnettii	86.53	6.00e-160	556.00
IUUC-Oar-089915	Ovis aries	86.20	5.00e-159	553.00
IUUC-Ptr-091124	Pan troglodytes	68.14	9.00e-119	419.00
IUUC-Pan-092035	Papio anubis	86.58	2.00e-160	558.00
IUUC-Psi-094096	Pelodiscus sinensis	81.58	7.00e-95	339.00
IUUC-Pno-094988	Phaeosphaeria nodorum	45.51	4.00e-71	261.00
IUUC-Ppa-095949	Physcomitrella patens	49.17	2.00e-84	305.00
IUUC-Pfo-096101	Poecilia formosa	83.89	2.00e-158	551.00
IUUC-Pab-097726	Pongo abelii	86.58	2.00e-160	558.00
IUUC-Pop-099617	Populus trichocarpa	48.17	4.00e-81	294.00
IUUC-Pca-101014	Procavia capensis	86.24	7.00e-160	556.00
IUUC-Ppe-101320	Prunus persica	46.18	5.00e-77	281.00
IUUC-Pva-102789	Pteropus vampyrus	75.84	8.00e-134	469.00
IUUC-Pgr-103479	Puccinia graminis	46.33	3.00e-75	275.00
IUUC-Ptt-103981	Puccinia triticina	47.33	2.00e-77	282.00
IUUC-Pte-104278	Pyrenophora teres	48.50	4.00e-80	291.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	48.50	4.00e-80	291.00
IUUC-Rno-105867	Rattus norvegicus	67.56	2.00e-110	391.00
IUUC-Sce-106251	Saccharomyces cerevisiae	45.25	2.00e-74	272.00
IUUC-Sha-107039	Sarcophilus harrisii	85.57	2.00e-159	554.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	51.00	9.00e-87	313.00
IUUC-Spo-108314	Schizosaccharomyces pombe	49.33	1.00e-82	299.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	52.16	9.00e-90	323.00
IUUC-Smo-108728	Selaginella moellendorffii	48.84	5.00e-79	287.00
IUUC-Sit-110801	Setaria italica	46.18	2.00e-77	282.00
IUUC-Sly-111326	Solanum lycopersicum	47.51	2.00e-79	288.00
IUUC-Stu-112458	Solanum tuberosum	46.84	7.00e-79	286.00
IUUC-Sbi-114063	Sorghum bicolor	45.85	4.00e-77	281.00
IUUC-Sre-115096	Sporisorium reilianum	46.60	7.00e-74	270.00
IUUC-Ssc-116080	Sus scrofa	86.24	9.00e-160	555.00
IUUC-Tgu-116988	Taeniopygia guttata	87.54	2.00e-162	564.00
IUUC-Tru-118766	Takifugu rubripes	84.56	7.00e-158	549.00
IUUC-Tni-120197	Tetraodon nigroviridis	84.56	2.00e-158	551.00
IUUC-Tca-121316	Theobroma cacao	45.85	1.00e-77	282.00
IUUC-Tre-122097	Trichoderma reesei	50.17	9.00e-84	303.00
IUUC-Tvi-122442	Trichoderma virens	50.17	3.00e-84	305.00
IUUC-Tae-125588	Triticum aestivum	45.85	3.00e-78	285.00
IUUC-Tur-126334	Triticum urartu	38.54	1.00e-58	219.00
IUUC-Tme-127038	Tuber melanosporum	53.33	4.00e-91	327.00
IUUC-Ttr-128659	Tursiops truncatus	82.03	1.00e-144	505.00
IUUC-Uma-129464	Ustilago maydis	46.28	1.00e-72	266.00
IUUC-Vda-129841	Verticillium dahliae	52.16	9.00e-87	313.00
IUUC-Vvi-131076	Vitis vinifera	47.68	5.00e-78	284.00
IUUC-Xtr-132395	Xenopus tropicalis	86.24	1.00e-160	558.00
IUUC-Xma-133383	Xiphophorus maculatus	83.89	3.00e-158	550.00
IUUC-Yli-134586	Yarrowia lipolytica	47.84	6.00e-78	283.00
IUUC-Zma-135904	Zea mays	46.51	1.00e-77	282.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence