iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-027053

Ensembl Protein ID

AAW44444

UniProt Accession

Q5KEH7; Q5KEH7_CRYNJ

Genbank Protein ID

AAW44444.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

AE017347

Gene Name

CNG00480

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNG00480	AAW44444	AAW44444

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-35	117.5	52	88
UBD/Beta-Prp	1.30e-76	256.1	3	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f ++ ++++sG+dD +ikvW++++ ++l
   Q: 52   HDGPVRGICFhPTqPIFCSGGDDYKIKVWNYKQRKCL 88
           99*********888****************9998886 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           + t +++++ +++ ++f+p+++lla++  +gti++w++++g+l+ ++ +h+++v+ ++f+p+++i+ +g++D+ ikvw+++++kc+ tl+gh d+v+++ f
   Q: 3    MLTKFESKSPRVKGIAFHPKQPLLAASLHNGTIQLWNYQMGTLVDRYDEHDGPVRGICFHPTQPIFCSGGDDYKIKVWNYKQRKCLFTLTGHLDYVRTVFF 103
           5678899999******************************************************************************************* PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl................................ktgkl 171
           +++  +++s+s+d+tir+w++++++c+  +l+gh++ ++c+++hp ++l++s+s D tvr+Wd+                                +t+ +
   Q: 104  HREYPWIISASDDQTIRIWNWQSRTCIA-ILTGHNHYIMCAQFHPWDDLVISASMDLTVRVWDIsglrkknqasqapmsaeeqiarasqgqadlfgNTDAV 203
           ****************************.******************************************************************988888 PP
   S: 172  lrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisv 270
           ++   +gh++ v++ sf+++ + +vs+++d++vklw +++++   v++++gh +nv++  f+p++e+++s+s+D++ir Wd+++++ ++t+ +++++++  
   Q: 204  VKYVLEGHDRGVNWASFHPTLPLIVSCGDDRQVKLWLMSETKAweVDSCRGHFNNVSMTMFHPKHELILSASEDKTIRAWDMTKRTAVQTFRREHDRFWVL 304
           8888777********************************888778******************************************************** PP
   S: 271  avlsfgdnvlvlgsedskvniwklkkne 298
           ++ +++ n +++g  d+ + ++kl++++
   Q: 305  TA-HPELNLFAAGH-DNGLIVFKLERER 330
           *9.77777766665.5677788887765 PP

Organism

Cryptococcus neoformans

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MQMLTKFESK SPRVKGIAFH PKQPLLAASL HNGTIQLWNY QMGTLVDRYD EHDGPVRGIC 60
FHPTQPIFCS GGDDYKIKVW NYKQRKCLFT LTGHLDYVRT VFFHREYPWI ISASDDQTIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAACTCTATA CTCTCCAAAC TCTCCCCAAA ATCGTATATC AGTCGACAGC GCTGAGAATA 60
ACAGGCCGTC CGCACCAGTC CACTCCGATT TCCCGCTTCT TCTGACTCGC AACACTATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

cne:CNG00480

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	57.82	0.00e+00	1034.00
IUUC-Aml-001758	Ailuropoda melanoleuca	51.96	0.00e+00	1276.00
IUUC-Atr-002493	Amborella trichopoda	50.73	0.00e+00	1194.00
IUUC-Apl-003385	Anas platyrhynchos	48.37	0.00e+00	977.00
IUUC-Aca-005154	Anolis carolinensis	71.50	1.00e-91	327.00
IUUC-Aly-006494	Arabidopsis lyrata	47.33	0.00e+00	1106.00
IUUC-Ath-007360	Arabidopsis thaliana	50.52	0.00e+00	1186.00
IUUC-Ago-007992	Ashbya gossypii	48.46	0.00e+00	1082.00
IUUC-Acl-008027	Aspergillus clavatus	55.56	0.00e+00	1349.00
IUUC-Afl-008644	Aspergillus flavus	55.68	0.00e+00	1343.00
IUUC-Afu-008964	Aspergillus fumigatus	55.28	0.00e+00	1354.00
IUUC-Ani-009379	Aspergillus nidulans	64.49	0.00e+00	1145.00
IUUC-Ang-009756	Aspergillus niger	55.75	0.00e+00	1369.00
IUUC-Aor-010174	Aspergillus oryzae	55.60	0.00e+00	1342.00
IUUC-Ate-010302	Aspergillus terreus	55.46	0.00e+00	1386.00
IUUC-Ame-011229	Astyanax mexicanus	51.77	0.00e+00	1265.00
IUUC-Bgr-012300	Blumeria graminis	54.86	0.00e+00	1292.00
IUUC-Bta-012524	Bos taurus	52.34	0.00e+00	1268.00
IUUC-Bci-013781	Botrytis cinerea	56.37	0.00e+00	1367.00
IUUC-Bdi-014549	Brachypodium distachyon	50.44	0.00e+00	1212.00
IUUC-Bol-015925	Brassica oleracea	58.00	0.00e+00	1019.00
IUUC-Bra-017823	Brassica rapa	57.52	0.00e+00	1011.00
IUUC-Cel-018115	Caenorhabditis elegans	54.87	0.00e+00	945.00
IUUC-Cja-019107	Callithrix jacchus	51.93	0.00e+00	1259.00
IUUC-Cfa-020675	Canis familiaris	51.75	0.00e+00	1254.00
IUUC-Cpo-021813	Cavia porcellus	52.18	0.00e+00	1283.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	58.27	0.00e+00	1023.00
IUUC-Csa-023523	Chlorocebus sabaeus	52.34	0.00e+00	1289.00
IUUC-Cho-024704	Choloepus hoffmanni	67.63	9.00e-131	459.00
IUUC-Cin-025572	Ciona intestinalis	49.68	0.00e+00	1229.00
IUUC-Csv-025864	Ciona savignyi	56.16	0.00e+00	966.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	64.02	0.00e+00	1143.00
IUUC-Cme-027222	Cyanidioschyzon merolae	42.23	5.00e-146	510.00
IUUC-Dre-027421	Danio rerio	51.77	0.00e+00	1265.00
IUUC-Dno-029303	Dasypus novemcinctus	52.22	0.00e+00	1287.00
IUUC-Dor-030290	Dipodomys ordii	48.95	7.00e-156	543.00
IUUC-Dse-031543	Dothistroma septosporum	54.68	0.00e+00	1280.00
IUUC-Dme-031945	Drosophila melanogaster	56.85	0.00e+00	975.00
IUUC-Ete-032873	Echinops telfairi	56.69	0.00e+00	990.00
IUUC-Eca-033773	Equus caballus	51.00	0.00e+00	1238.00
IUUC-Eeu-034874	Erinaceus europaeus	41.23	0.00e+00	634.00
IUUC-Fca-035739	Felis catus	51.77	0.00e+00	1259.00
IUUC-Fal-037263	Ficedula albicollis	48.70	0.00e+00	1135.00
IUUC-Fox-037738	Fusarium oxysporum	54.42	0.00e+00	1354.00
IUUC-Fso-038153	Fusarium solani	54.31	0.00e+00	1337.00
IUUC-Gmo-039602	Gadus morhua	48.28	0.00e+00	1162.00
IUUC-Ggr-039931	Gaeumannomyces graminis	62.84	0.00e+00	1123.00
IUUC-Gga-040590	Gallus gallus	52.04	0.00e+00	1281.00
IUUC-Gac-041318	Gasterosteus aculeatus	51.44	0.00e+00	1258.00
IUUC-Gma-043567	Glycine max	58.26	0.00e+00	1025.00
IUUC-Ggo-045029	Gorilla gorilla	51.96	0.00e+00	1280.00
IUUC-Hsa-046078	Homo sapiens	51.88	0.00e+00	1278.00
IUUC-Hvu-047556	Hordeum vulgare	50.56	0.00e+00	1216.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	44.10	0.00e+00	705.00
IUUC-Kpa-049256	Komagataella pastoris	49.02	0.00e+00	1141.00
IUUC-Lch-049706	Latimeria chalumnae	51.94	0.00e+00	1262.00
IUUC-Lpe-051553	Leersia perrieri	57.51	0.00e+00	1023.00
IUUC-Loc-051867	Lepisosteus oculatus	40.76	0.00e+00	842.00
IUUC-Lma-053138	Leptosphaeria maculans	55.04	0.00e+00	1330.00
IUUC-Laf-053510	Loxodonta africana	52.29	0.00e+00	1285.00
IUUC-Mcc-055836	Macaca mulatta	52.04	0.00e+00	1283.00
IUUC-Meu-056238	Macropus eugenii	54.41	0.00e+00	746.00
IUUC-Mor-057172	Magnaporthe oryzae	53.68	0.00e+00	1335.00
IUUC-Mpo-057300	Magnaporthe poae	54.93	0.00e+00	1329.00
IUUC-Mtr-058248	Medicago truncatula	58.38	0.00e+00	1034.00
IUUC-Mla-059019	Melampsora laricipopulina	64.42	0.00e+00	1608.00
IUUC-Mga-059499	Meleagris gallopavo	52.08	0.00e+00	1275.00
IUUC-Mvi-060336	Microbotryum violaceum	64.82	0.00e+00	1592.00
IUUC-Mmr-061102	Microcebus murinus	52.48	0.00e+00	1271.00
IUUC-Mdo-062594	Monodelphis domestica	51.84	0.00e+00	1292.00
IUUC-Mmu-063736	Mus musculus	51.96	0.00e+00	1277.00
IUUC-Mac-065398	Musa acuminata	47.27	0.00e+00	1104.00
IUUC-Mpu-066701	Mustela putorius furo	51.97	0.00e+00	1277.00
IUUC-Mlu-067392	Myotis lucifugus	52.10	0.00e+00	1277.00
IUUC-Nfi-068270	Neosartorya fischeri	55.37	0.00e+00	1341.00
IUUC-Ncr-068892	Neurospora crassa	54.71	0.00e+00	1342.00
IUUC-Nle-069634	Nomascus leucogenys	62.70	0.00e+00	910.00
IUUC-Opr-070952	Ochotona princeps	40.51	2.00e-174	604.00
IUUC-Ont-072488	Oreochromis niloticus	52.43	0.00e+00	1259.00
IUUC-Ocu-074211	Oryctolagus cuniculus	52.18	0.00e+00	1282.00
IUUC-Oba-075761	Oryza barthii	58.39	0.00e+00	1041.00
IUUC-Obr-076429	Oryza brachyantha	58.29	0.00e+00	1040.00
IUUC-Ogl-077364	Oryza glaberrima	58.39	0.00e+00	1041.00
IUUC-Ogu-078257	Oryza glumaepatula	58.39	0.00e+00	1040.00
IUUC-Oin-079274	Oryza indica	58.27	0.00e+00	1040.00
IUUC-Olo-080466	Oryza longistaminata	59.37	0.00e+00	1038.00
IUUC-Ome-081993	Oryza meridionalis	60.32	0.00e+00	987.00
IUUC-Oni-082874	Oryza nivara	58.32	0.00e+00	1041.00
IUUC-Opu-083885	Oryza punctata	50.57	0.00e+00	1206.00
IUUC-Oru-084274	Oryza rufipogon	58.27	0.00e+00	1039.00
IUUC-Osa-085565	Oryza sativa	58.27	0.00e+00	1039.00
IUUC-Ola-086921	Oryzias latipes	51.67	0.00e+00	1254.00
IUUC-Olu-087639	Ostreococcus lucimarinus	50.72	0.00e+00	1207.00
IUUC-Oga-087991	Otolemur garnettii	49.84	0.00e+00	1202.00
IUUC-Oar-089590	Ovis aries	52.34	0.00e+00	1285.00
IUUC-Ptr-090808	Pan troglodytes	51.96	0.00e+00	1280.00
IUUC-Pan-092475	Papio anubis	51.98	0.00e+00	1276.00
IUUC-Psi-093044	Pelodiscus sinensis	52.25	0.00e+00	869.00
IUUC-Pno-094839	Phaeosphaeria nodorum	54.21	0.00e+00	1270.00
IUUC-Ppa-095254	Physcomitrella patens	59.62	0.00e+00	1060.00
IUUC-Pfo-097493	Poecilia formosa	60.21	0.00e+00	1057.00
IUUC-Pab-098497	Pongo abelii	52.26	0.00e+00	1289.00
IUUC-Pop-099992	Populus trichocarpa	58.28	0.00e+00	1028.00
IUUC-Pca-100413	Procavia capensis	55.97	0.00e+00	655.00
IUUC-Ppe-101899	Prunus persica	57.93	0.00e+00	1029.00
IUUC-Pva-102126	Pteropus vampyrus	50.32	0.00e+00	1214.00
IUUC-Pgr-103376	Puccinia graminis	64.93	0.00e+00	1636.00
IUUC-Ptt-103978	Puccinia triticina	58.70	0.00e+00	1410.00
IUUC-Pte-104126	Pyrenophora teres	54.05	0.00e+00	1279.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	47.76	0.00e+00	910.00
IUUC-Rno-105428	Rattus norvegicus	52.42	0.00e+00	1284.00
IUUC-Sce-106464	Saccharomyces cerevisiae	46.52	0.00e+00	1047.00
IUUC-Sha-107301	Sarcophilus harrisii	52.00	0.00e+00	1262.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	50.49	0.00e+00	1222.00
IUUC-Spo-108217	Schizosaccharomyces pombe	51.49	0.00e+00	1275.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	56.13	0.00e+00	1369.00
IUUC-Smo-109582	Selaginella moellendorffii	58.78	0.00e+00	1065.00
IUUC-Sit-109697	Setaria italica	58.16	0.00e+00	1040.00
IUUC-Sly-111759	Solanum lycopersicum	51.45	0.00e+00	1237.00
IUUC-Stu-112564	Solanum tuberosum	51.09	0.00e+00	1233.00
IUUC-Sar-113313	Sorex araneus	41.10	2.00e-175	607.00
IUUC-Sbi-114388	Sorghum bicolor	58.04	0.00e+00	1041.00
IUUC-Sre-115209	Sporisorium reilianum	70.73	0.00e+00	1265.00
IUUC-Ssc-115933	Sus scrofa	52.34	0.00e+00	1285.00
IUUC-Tgu-117109	Taeniopygia guttata	47.56	2.00e-97	347.00
IUUC-Tru-117772	Takifugu rubripes	51.32	0.00e+00	1245.00
IUUC-Tsy-119105	Tarsius syrichta	49.95	0.00e+00	988.00
IUUC-Tni-120556	Tetraodon nigroviridis	38.42	0.00e+00	737.00
IUUC-Tca-121046	Theobroma cacao	50.53	0.00e+00	1210.00
IUUC-Tre-121951	Trichoderma reesei	54.78	0.00e+00	1319.00
IUUC-Tvi-122359	Trichoderma virens	55.55	0.00e+00	1346.00
IUUC-Tae-123688	Triticum aestivum	50.52	0.00e+00	1213.00
IUUC-Tur-126754	Triticum urartu	57.70	0.00e+00	1033.00
IUUC-Tme-127170	Tuber melanosporum	56.17	0.00e+00	1379.00
IUUC-Tbe-127882	Tupaia belangeri	47.83	2.00e-148	518.00
IUUC-Ttr-128217	Tursiops truncatus	50.04	0.00e+00	1211.00
IUUC-Uma-129337	Ustilago maydis	70.44	0.00e+00	1262.00
IUUC-Vda-129828	Verticillium dahliae	53.95	0.00e+00	1318.00
IUUC-Vpa-130537	Vicugna pacos	51.48	0.00e+00	1263.00
IUUC-Vvi-130958	Vitis vinifera	58.08	0.00e+00	1035.00
IUUC-Xtr-132857	Xenopus tropicalis	50.45	0.00e+00	1185.00
IUUC-Xma-133138	Xiphophorus maculatus	60.21	0.00e+00	1058.00
IUUC-Yli-134399	Yarrowia lipolytica	55.90	0.00e+00	956.00
IUUC-Zma-135612	Zea mays	49.84	0.00e+00	1192.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence