iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-025943

UUCD1 version

UUC-CiS-00215

Ensembl Protein ID

ENSCSAVP00000005628.1

UniProt Accession

H2YJX9; H2YJX9_CIOSA

Protein Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000003355.1	ENSCSAVT00000005703.1	ENSCSAVP00000005628.1
ENSCSAVG00000003355.1	ENSCSAVT00000005704.1	ENSCSAVP00000005629.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-46	154.1	304	335
UBD/Beta-Prp	6.20e-57	193.0	57	336

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf....sdtllvsGsdDgtikvWDl 30
           H+ +v+++a+    + +ll+s+sdDg ik+W++
   Q: 304  HEQDVNSVAWnpviP-GLLASCSDDGCIKLWNV 335
           99********97776.9***************7 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkc 86
           l++ h+  i++v +sp +s la++s d+ti +wd ++g++   ++l+ghe+ev+av +s++g++++t+s+D+ + +w+++    +++c
   Q: 57   LQDGHQRTIRKVGWSPCGSKLASASFDATICIWDKSSGQFesAATLEGHENEVKAVAWSQSGEYIATCSRDKSVWIWSVDeeedDFEC 144
           7889999*********************************9999*********************************8888888**** PP
   S: 87   vhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl....... 166
             +l+ h+++v +++++p  + ++s+s d+t+++++ + g++++   l gh+++v++v++++dg+ lvsGs D+tvr+W+        
   Q: 145  AGVLTTHTQDVKDIAWHPFEQIVASASYDDTLNLFKADDGEWVSIaSLGGHTSTVWTVSWSKDGRRLVSGSGDKTVRIWQRfdpgnve 232
           ******************99***********************988999*************************************** PP
   S: 167  ........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq....tgec.......vrtlnghtdnvksvrfs.pnd 234
                   +t k++ tl+g+ ++++y++++ ++   ++++s d+++ ++  +    +            + n+h++ v+sv+      
   Q: 233  giatkgenPTWKCVCTLSGYFKQPIYCVTWCHQTDMIAACSGDNSIVIFREEnssnN--SepvftaiSSAPNAHEQDVNSVAWNpVIP 318
           ***************************************************976652..14456665777899**********94457 PP
   S: 235  erlvsgssDgsiriWdlr 252
            +l+s+s+Dg i++W+++
   Q: 319  GLLASCSDDGCIKLWNVD 336
           799************976 PP

Organism

Ciona savignyi

Functional Description
(View)

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

IAMTTALQCI DNLKDHNDRV WDVKWNPKGT LLASCGTDKS IRIWGKEGNK WVCKSILQDG 60
HQRTIRKVGW SPCGSKLASA SFDATICIWD KSSGQFESAA TLEGHENEVK AVAWSQSGEY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCGCCATGA CCACAGCATT ACAATGCATC GATAATTTAA AGGATCACAA CGACAGAGTT 60
TGGGATGTCA AGTGGAACCC GAAAGGAACT CTTTTAGCTT CATGTGGAAC TGATAAATCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	38.61	5.00e-59	220.00
IUUC-Aml-001317	Ailuropoda melanoleuca	54.65	1.00e-101	361.00
IUUC-Atr-003029	Amborella trichopoda	44.48	6.00e-76	275.00
IUUC-Apl-004042	Anas platyrhynchos	50.00	2.00e-34	135.00
IUUC-Aly-006458	Arabidopsis lyrata	42.98	9.00e-75	271.00
IUUC-Ath-006671	Arabidopsis thaliana	43.57	5.00e-75	273.00
IUUC-Ago-007820	Ashbya gossypii	37.57	7.00e-53	199.00
IUUC-Acl-008042	Aspergillus clavatus	30.02	5.00e-45	173.00
IUUC-Afl-008639	Aspergillus flavus	30.86	1.00e-45	175.00
IUUC-Afu-008899	Aspergillus fumigatus	31.64	7.00e-43	166.00
IUUC-Ani-009453	Aspergillus nidulans	29.63	1.00e-46	178.00
IUUC-Ang-009758	Aspergillus niger	31.67	1.00e-47	181.00
IUUC-Aor-010212	Aspergillus oryzae	30.86	1.00e-45	175.00
IUUC-Ate-010314	Aspergillus terreus	30.50	8.00e-48	182.00
IUUC-Ame-010676	Astyanax mexicanus	53.13	4.00e-104	369.00
IUUC-Bgr-012095	Blumeria graminis	30.27	5.00e-38	150.00
IUUC-Bta-012884	Bos taurus	54.65	2.00e-101	360.00
IUUC-Bci-013622	Botrytis cinerea	29.34	1.00e-38	152.00
IUUC-Bdi-014614	Brachypodium distachyon	45.00	6.00e-77	279.00
IUUC-Bol-016439	Brassica oleracea	40.36	2.00e-70	257.00
IUUC-Bra-016830	Brassica rapa	39.88	2.00e-69	253.00
IUUC-Cel-018709	Caenorhabditis elegans	40.12	1.00e-64	238.00
IUUC-Cja-019822	Callithrix jacchus	54.05	1.00e-100	357.00
IUUC-Cfa-020823	Canis familiaris	54.35	2.00e-101	360.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	44.38	1.00e-73	268.00
IUUC-Csa-023754	Chlorocebus sabaeus	54.35	6.00e-102	362.00
IUUC-Cin-025395	Ciona intestinalis	82.14	2.00e-172	595.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	28.38	1.00e-33	135.00
IUUC-Cne-026939	Cryptococcus neoformans	30.16	7.00e-45	173.00
IUUC-Cme-027239	Cyanidioschyzon merolae	38.74	5.00e-45	173.00
IUUC-Dre-028172	Danio rerio	51.04	1.00e-100	357.00
IUUC-Dno-029472	Dasypus novemcinctus	56.45	7.00e-90	321.00
IUUC-Dor-031134	Dipodomys ordii	46.85	2.00e-79	287.00
IUUC-Dse-031535	Dothistroma septosporum	27.70	1.00e-39	155.00
IUUC-Dme-032020	Drosophila melanogaster	57.23	7.00e-108	381.00
IUUC-Eca-033700	Equus caballus	54.95	2.00e-103	367.00
IUUC-Eeu-035010	Erinaceus europaeus	54.35	1.00e-99	354.00
IUUC-Fca-036309	Felis catus	50.00	3.00e-94	336.00
IUUC-Fal-037243	Ficedula albicollis	60.93	6.00e-69	251.00
IUUC-Fox-038058	Fusarium oxysporum	28.93	8.00e-38	150.00
IUUC-Fso-038459	Fusarium solani	28.31	3.00e-37	147.00
IUUC-Gmo-039375	Gadus morhua	50.45	5.00e-91	325.00
IUUC-Ggr-040002	Gaeumannomyces graminis	31.01	1.00e-34	139.00
IUUC-Gga-040294	Gallus gallus	56.31	3.00e-83	300.00
IUUC-Gac-042499	Gasterosteus aculeatus	52.69	8.00e-95	338.00
IUUC-Gma-043543	Glycine max	41.98	7.00e-74	268.00
IUUC-Ggo-045181	Gorilla gorilla	54.35	6.00e-102	362.00
IUUC-Hsa-046528	Homo sapiens	54.35	6.00e-102	362.00
IUUC-Hvu-047341	Hordeum vulgare	50.81	1.00e-48	184.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	54.95	1.00e-102	364.00
IUUC-Kpa-049353	Komagataella pastoris	35.88	3.00e-57	213.00
IUUC-Lch-049763	Latimeria chalumnae	53.43	2.00e-104	370.00
IUUC-Lpe-051500	Leersia perrieri	40.70	4.00e-72	263.00
IUUC-Loc-052021	Lepisosteus oculatus	56.16	2.00e-104	370.00
IUUC-Lma-053331	Leptosphaeria maculans	30.52	3.00e-45	175.00
IUUC-Laf-054558	Loxodonta africana	54.35	7.00e-101	358.00
IUUC-Mcc-055374	Macaca mulatta	54.05	3.00e-101	359.00
IUUC-Meu-056042	Macropus eugenii	58.57	2.00e-67	246.00
IUUC-Mor-057187	Magnaporthe oryzae	31.34	7.00e-36	143.00
IUUC-Mtr-058072	Medicago truncatula	42.57	2.00e-74	270.00
IUUC-Mla-059108	Melampsora laricipopulina	31.74	3.00e-49	187.00
IUUC-Mga-059370	Meleagris gallopavo	44.34	5.00e-63	232.00
IUUC-Mvi-060495	Microbotryum violaceum	34.82	3.00e-52	197.00
IUUC-Mmr-060902	Microcebus murinus	54.05	1.00e-100	357.00
IUUC-Mdo-062510	Monodelphis domestica	56.46	9.00e-102	361.00
IUUC-Mmu-063575	Mus musculus	54.65	3.00e-101	359.00
IUUC-Mac-065322	Musa acuminata	45.03	6.00e-80	289.00
IUUC-Mpu-065925	Mustela putorius furo	54.35	1.00e-101	360.00
IUUC-Mlu-067755	Myotis lucifugus	54.05	2.00e-101	360.00
IUUC-Nfi-068327	Neosartorya fischeri	28.60	2.00e-42	165.00
IUUC-Ncr-068845	Neurospora crassa	27.07	3.00e-30	124.00
IUUC-Nle-069406	Nomascus leucogenys	53.45	2.00e-98	350.00
IUUC-Opr-070416	Ochotona princeps	44.14	3.00e-71	259.00
IUUC-Ont-071936	Oreochromis niloticus	53.59	6.00e-97	345.00
IUUC-Oan-073452	Ornithorhynchus anatinus	54.82	1.00e-44	170.00
IUUC-Ocu-074791	Oryctolagus cuniculus	54.35	2.00e-100	357.00
IUUC-Oba-075636	Oryza barthii	43.86	2.00e-77	280.00
IUUC-Obr-076742	Oryza brachyantha	44.25	1.00e-66	244.00
IUUC-Ogl-077766	Oryza glaberrima	43.86	2.00e-77	280.00
IUUC-Ogu-079039	Oryza glumaepatula	43.86	1.00e-77	281.00
IUUC-Oin-079315	Oryza indica	44.18	7.00e-67	245.00
IUUC-Olo-080669	Oryza longistaminata	39.18	1.00e-70	258.00
IUUC-Ome-081490	Oryza meridionalis	43.86	1.00e-77	281.00
IUUC-Oni-082572	Oryza nivara	43.86	2.00e-77	280.00
IUUC-Opu-083732	Oryza punctata	44.94	6.00e-79	285.00
IUUC-Oru-084763	Oryza rufipogon	43.86	2.00e-77	280.00
IUUC-Osa-085372	Oryza sativa	43.86	2.00e-77	280.00
IUUC-Ola-087379	Oryzias latipes	52.69	4.00e-94	336.00
IUUC-Olu-087801	Ostreococcus lucimarinus	33.04	7.00e-35	139.00
IUUC-Oga-089076	Otolemur garnettii	54.35	3.00e-101	359.00
IUUC-Oar-090022	Ovis aries	54.95	5.00e-102	362.00
IUUC-Ptr-090809	Pan troglodytes	54.35	6.00e-102	362.00
IUUC-Pan-091685	Papio anubis	54.49	8.00e-103	365.00
IUUC-Psi-093046	Pelodiscus sinensis	56.76	1.00e-104	371.00
IUUC-Pma-094181	Petromyzon marinus	53.89	1.00e-106	377.00
IUUC-Pno-094882	Phaeosphaeria nodorum	28.78	6.00e-43	166.00
IUUC-Ppa-095172	Physcomitrella patens	41.91	3.00e-71	260.00
IUUC-Pfo-096396	Poecilia formosa	52.11	1.00e-95	341.00
IUUC-Pab-098427	Pongo abelii	53.75	7.00e-100	355.00
IUUC-Pop-100016	Populus trichocarpa	44.44	2.00e-77	280.00
IUUC-Pca-101048	Procavia capensis	54.95	4.00e-102	362.00
IUUC-Ppe-102050	Prunus persica	39.38	4.00e-71	259.00
IUUC-Pva-103117	Pteropus vampyrus	55.26	6.00e-103	365.00
IUUC-Pgr-103307	Puccinia graminis	31.42	4.00e-50	190.00
IUUC-Ptt-103938	Puccinia triticina	33.93	4.00e-43	166.00
IUUC-Pte-104315	Pyrenophora teres	28.50	3.00e-43	167.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	29.48	3.00e-43	167.00
IUUC-Rno-105523	Rattus norvegicus	55.12	1.00e-100	358.00
IUUC-Sce-106297	Saccharomyces cerevisiae	35.59	9.00e-54	202.00
IUUC-Sha-106981	Sarcophilus harrisii	56.45	2.00e-87	313.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	37.65	1.00e-56	212.00
IUUC-Spo-108214	Schizosaccharomyces pombe	38.19	1.00e-51	195.00
IUUC-Smo-109034	Selaginella moellendorffii	41.06	2.00e-70	257.00
IUUC-Sit-110663	Setaria italica	45.00	1.00e-78	285.00
IUUC-Sly-110898	Solanum lycopersicum	41.40	2.00e-67	248.00
IUUC-Stu-112647	Solanum tuberosum	42.38	5.00e-56	209.00
IUUC-Sbi-114288	Sorghum bicolor	45.03	2.00e-77	280.00
IUUC-Sre-115065	Sporisorium reilianum	33.64	2.00e-59	221.00
IUUC-Ssc-115960	Sus scrofa	51.94	1.00e-103	367.00
IUUC-Tru-118382	Takifugu rubripes	55.56	1.00e-106	377.00
IUUC-Tsy-119585	Tarsius syrichta	48.95	3.00e-83	300.00
IUUC-Tni-120133	Tetraodon nigroviridis	54.24	8.00e-100	355.00
IUUC-Tca-121167	Theobroma cacao	42.65	1.00e-69	254.00
IUUC-Tre-122119	Trichoderma reesei	27.78	7.00e-37	146.00
IUUC-Tvi-122407	Trichoderma virens	27.89	1.00e-39	155.00
IUUC-Tae-125748	Triticum aestivum	43.86	2.00e-73	267.00
IUUC-Tur-126682	Triticum urartu	44.81	1.00e-58	217.00
IUUC-Tme-127095	Tuber melanosporum	33.77	1.00e-50	191.00
IUUC-Tbe-128004	Tupaia belangeri	54.05	9.00e-101	358.00
IUUC-Ttr-129284	Tursiops truncatus	53.10	6.00e-99	352.00
IUUC-Uma-129527	Ustilago maydis	32.94	3.00e-58	217.00
IUUC-Vda-129854	Verticillium dahliae	28.16	2.00e-34	138.00
IUUC-Vpa-130681	Vicugna pacos	63.25	4.00e-33	133.00
IUUC-Vvi-131004	Vitis vinifera	44.67	2.00e-74	270.00
IUUC-Xtr-131928	Xenopus tropicalis	52.25	1.00e-94	338.00
IUUC-Xma-134290	Xiphophorus maculatus	50.75	5.00e-92	329.00
IUUC-Yli-134364	Yarrowia lipolytica	40.00	2.00e-60	224.00
IUUC-Zma-135658	Zea mays	43.11	7.00e-74	268.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence