iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000010591.8	ENSRNOT00000056198.5	ENSRNOP00000053044.3
ENSRNOG00000010591.8	ENSRNOT00000075895.2	ENSRNOP00000068325.1
ENSRNOG00000010591.8	ENSRNOT00000090218.1	ENSRNOP00000068854.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.50e-18	67.1	295	342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 295  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLLPP-LPDVPKGD-WRCPKCVA 342
           8*********88.6*******************.*******7.******75 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAGVGPGGYA AEFVPPPECP VFEPSWEEFT DPLSFIGRIR PLAEKTGICK IRPPKDWQPP 60
FACEVKTFRF TPRVQRLNEL EAMTRVRLDF LDQLAKFWEL QGSTLKIPVV ERKILDLYAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCCTCTC GAGGAGAGGT CGCGGAGCCA TCAGGGGCCA CGCACCCAGA GTGGACGGAG 60
AGTGCAGAAC CTTGACCGGC AAGCTGAGAA AAAAAGGCAC GCCGGCTGTC ATGGAAGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:0008584--P:male gonad development
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0007283--P:spermatogenesis

KEGG

rno:312678

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	96.75	0.00e+00	2950.00
IUUC-Atr-002595	Amborella trichopoda	30.63	3.00e-124	441.00
IUUC-Apl-004141	Anas platyrhynchos	91.51	0.00e+00	2805.00
IUUC-Aca-004952	Anolis carolinensis	89.71	0.00e+00	2818.00
IUUC-Ani-009139	Aspergillus nidulans	32.62	1.00e-107	385.00
IUUC-Ate-010453	Aspergillus terreus	33.81	5.00e-106	380.00
IUUC-Ame-011323	Astyanax mexicanus	76.32	0.00e+00	2067.00
IUUC-Bgr-012241	Blumeria graminis	30.54	3.00e-116	414.00
IUUC-Bta-012902	Bos taurus	95.63	0.00e+00	2944.00
IUUC-Cja-018988	Callithrix jacchus	94.38	0.00e+00	2753.00
IUUC-Cfa-020212	Canis familiaris	95.74	0.00e+00	2910.00
IUUC-Cpo-022221	Cavia porcellus	96.26	0.00e+00	2073.00
IUUC-Csa-023575	Chlorocebus sabaeus	96.79	0.00e+00	2850.00
IUUC-Cho-024280	Choloepus hoffmanni	91.89	0.00e+00	2726.00
IUUC-Cin-025321	Ciona intestinalis	48.81	0.00e+00	1072.00
IUUC-Csv-026185	Ciona savignyi	48.01	0.00e+00	1172.00
IUUC-Dre-027909	Danio rerio	75.37	0.00e+00	1657.00
IUUC-Dno-029473	Dasypus novemcinctus	95.91	0.00e+00	2671.00
IUUC-Dor-030281	Dipodomys ordii	94.10	0.00e+00	1214.00
IUUC-Dme-032021	Drosophila melanogaster	47.05	0.00e+00	1123.00
IUUC-Eca-034265	Equus caballus	94.92	0.00e+00	2939.00
IUUC-Fca-035476	Felis catus	95.80	0.00e+00	2943.00
IUUC-Fal-037078	Ficedula albicollis	90.88	0.00e+00	2472.00
IUUC-Ggr-039929	Gaeumannomyces graminis	29.63	5.00e-111	396.00
IUUC-Gga-040466	Gallus gallus	90.21	0.00e+00	2888.00
IUUC-Gac-042566	Gasterosteus aculeatus	75.46	0.00e+00	2119.00
IUUC-Ggo-044524	Gorilla gorilla	89.75	0.00e+00	2478.00
IUUC-Hsa-045821	Homo sapiens	96.69	0.00e+00	2949.00
IUUC-Kpa-049245	Komagataella pastoris	22.89	4.00e-38	154.00
IUUC-Lch-050630	Latimeria chalumnae	74.27	0.00e+00	2115.00
IUUC-Loc-051963	Lepisosteus oculatus	75.43	0.00e+00	2080.00
IUUC-Laf-053918	Loxodonta africana	89.55	0.00e+00	2548.00
IUUC-Mcc-055672	Macaca mulatta	95.27	0.00e+00	2950.00
IUUC-Mor-057198	Magnaporthe oryzae	30.44	3.00e-121	430.00
IUUC-Mpo-057317	Magnaporthe poae	30.21	1.00e-112	402.00
IUUC-Mtr-058113	Medicago truncatula	32.27	3.00e-97	350.00
IUUC-Mga-059192	Meleagris gallopavo	82.69	0.00e+00	2444.00
IUUC-Mmr-060968	Microcebus murinus	95.04	0.00e+00	2979.00
IUUC-Mdo-062945	Monodelphis domestica	94.33	0.00e+00	2783.00
IUUC-Mmu-063614	Mus musculus	98.88	0.00e+00	3001.00
IUUC-Mpu-066349	Mustela putorius furo	96.64	0.00e+00	2828.00
IUUC-Mlu-067363	Myotis lucifugus	96.04	0.00e+00	3015.00
IUUC-Ncr-068763	Neurospora crassa	29.59	6.00e-110	393.00
IUUC-Nle-070142	Nomascus leucogenys	96.63	0.00e+00	2950.00
IUUC-Opr-071002	Ochotona princeps	89.38	0.00e+00	1386.00
IUUC-Ont-072471	Oreochromis niloticus	78.07	0.00e+00	1891.00
IUUC-Oan-072797	Ornithorhynchus anatinus	78.25	0.00e+00	2014.00
IUUC-Ocu-074164	Oryctolagus cuniculus	95.21	0.00e+00	2999.00
IUUC-Oba-075388	Oryza barthii	32.11	2.00e-83	304.00
IUUC-Obr-076296	Oryza brachyantha	34.38	3.00e-97	351.00
IUUC-Ogu-079040	Oryza glumaepatula	27.95	1.00e-83	305.00
IUUC-Ome-081764	Oryza meridionalis	29.84	1.00e-101	365.00
IUUC-Oni-083012	Oryza nivara	27.86	7.00e-83	303.00
IUUC-Ola-087076	Oryzias latipes	74.45	0.00e+00	2100.00
IUUC-Oga-088350	Otolemur garnettii	94.67	0.00e+00	2886.00
IUUC-Oar-090045	Ovis aries	95.44	0.00e+00	2927.00
IUUC-Ptr-091199	Pan troglodytes	96.15	0.00e+00	2936.00
IUUC-Pan-092094	Papio anubis	92.03	0.00e+00	2873.00
IUUC-Psi-093550	Pelodiscus sinensis	90.84	0.00e+00	2576.00
IUUC-Pno-094879	Phaeosphaeria nodorum	29.77	7.00e-119	422.00
IUUC-Pfo-097266	Poecilia formosa	78.03	0.00e+00	1864.00
IUUC-Pab-098576	Pongo abelii	96.80	0.00e+00	2946.00
IUUC-Pca-100123	Procavia capensis	93.12	0.00e+00	1635.00
IUUC-Ppe-101504	Prunus persica	32.20	9.00e-103	369.00
IUUC-Pva-103109	Pteropus vampyrus	90.47	0.00e+00	2782.00
IUUC-Pte-104195	Pyrenophora teres	30.14	2.00e-123	438.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	30.14	3.00e-125	444.00
IUUC-Sha-107506	Sarcophilus harrisii	93.02	0.00e+00	2535.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	20.89	9.00e-34	139.00
IUUC-Spo-108283	Schizosaccharomyces pombe	23.43	3.00e-55	211.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	9.00e-11	62.40
IUUC-Sit-110534	Setaria italica	29.86	2.00e-121	431.00
IUUC-Sar-113052	Sorex araneus	95.21	0.00e+00	2939.00
IUUC-Sbi-114173	Sorghum bicolor	58.14	8.00e-12	64.70
IUUC-Tgu-116613	Taeniopygia guttata	90.41	0.00e+00	2800.00
IUUC-Tru-118604	Takifugu rubripes	75.05	0.00e+00	2157.00
IUUC-Tsy-119237	Tarsius syrichta	96.11	0.00e+00	1286.00
IUUC-Tni-120779	Tetraodon nigroviridis	74.61	0.00e+00	2133.00
IUUC-Tca-121478	Theobroma cacao	32.14	3.00e-105	377.00
IUUC-Tae-125894	Triticum aestivum	29.30	4.00e-111	397.00
IUUC-Tme-127087	Tuber melanosporum	30.93	5.00e-133	469.00
IUUC-Ttr-129242	Tursiops truncatus	93.73	0.00e+00	2840.00
IUUC-Uma-129590	Ustilago maydis	30.62	3.00e-134	474.00
IUUC-Vpa-130429	Vicugna pacos	88.19	0.00e+00	1440.00
IUUC-Xtr-131762	Xenopus tropicalis	76.57	0.00e+00	2268.00
IUUC-Xma-133693	Xiphophorus maculatus	75.08	0.00e+00	2135.00
IUUC-Zma-135829	Zea mays	29.96	6.00e-117	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence