iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pop-099222

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

CM000339

Gene Name

POPTRDRAFT_817095; POPTR_0003s05500g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0003s05500	POPTR_0003s05500.1	POPTR_0003s05500.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-35	119.9	216	256
UBD/Beta-Prp	5.60e-67	227.1	46	321

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 216  HQKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKSCVQT 256
           999*****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls 99
           +++++++v+ +p +++++++ ++gt+ +w+++++++ +s++  e +v++ kf+ ++++ v g++D++i+v++++t + + ++++h+d++++
   Q: 46   RSERVKSVDLHPTEPWILVSLYSGTVCIWNYQSQTMAKSFEVTELPVRSAKFIARKQWVVAGADDMHIRVYNYNTMDKIKVFEAHTDYIRC 136
           5678999************************************************************************************ PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls.. 187
           ++++p+  +++s s+d  i++wd+e+g+   ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h++ v++++  
   Q: 137  VAVHPTLPYVLSSSDDMLIKLWDWEKGWACTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDA-HQKGVNCVDyf 226
           ****************************9999*********************************************98.*********64 PP
   S: 188  fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdn 278
              ++++l++gs+d t k+wd+qt++cv+tl+ght nv+ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v++v +++ +++
   Q: 227  TGGDKPYLITGSDDHTAKVWDYQTKSCVQTLEGHTHNVSAVCFHPEIPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAVGYMKGSRR 317
           44555******************************************************************************99777666 PP
   S: 279  vlvl 282
           v++ 
   Q: 318  VVIG 321
           6643 PP

Organism

Populus trichocarpa

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MWDIGISSAL FGSSESEVLD ARIDFLVTKW SVQPLRLEIK RKLAQRSERV KSVDLHPTEP 60
WILVSLYSGT VCIWNYQSQT MAKSFEVTEL PVRSAKFIAR KQWVVAGADD MHIRVYNYNT 120

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Nucleotide Sequence
(Fasta)

ATGTGGGACA TTGGAATCAG TTCCGCTCTG TTTGGTAGCT CGGAATCGGA GGTTCTCGAT 60
GCTCGCATTG ATTTCTTAGT GACCAAATGG AGTGTTCAGG TCTTGAATTT TGCTGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

pop:POPTR_0003s05500g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ete-033166	Echinops telfairi	58.50	0.00e+00	705.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence