iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004602

Ensembl Protein ID

ENSACAP00000015710.3

UniProt Accession

H9GMT8; H9GMT8_ANOCA

Protein Name

Uncharacterized protein

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000015968.3	ENSACAT00000016025.3	ENSACAP00000015710.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	66.50	5.00e-147	518.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MIDQSQRGNG LKGVEGGGSR FEFKCSSELC GAIMEKIGKE NLNGHPCHHS KAAAMGGPKR 60
VPVAQNRIHG NKVQTQCVLT ATNVPQRVPV QLQKPPIPSS KHSSQLNQHR PTSHVQSTSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTGACC AATCGCAGCG CGGGAACGGT TTAAAGGGCG TTGAAGGAGG CGGGAGCAGG 60
TTTGAATTCA AATGTTCGTC GGAGTTGTGT GGAGGTGAGT AGTGGGCCTT ATCGGGATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0032133--C:chromosome passenger complex
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0032465--P:regulation of cytokinesis
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	65.25	1.00e-108	385.00
IUUC-Aml-001426	Ailuropoda melanoleuca	66.75	2.00e-147	514.00
IUUC-Atr-002453	Amborella trichopoda	64.21	5.00e-109	386.00
IUUC-Apl-003626	Anas platyrhynchos	68.99	2.00e-151	528.00
IUUC-Aly-005878	Arabidopsis lyrata	65.07	1.00e-105	375.00
IUUC-Ath-007117	Arabidopsis thaliana	64.47	3.00e-106	377.00
IUUC-Acl-008199	Aspergillus clavatus	58.78	1.00e-86	312.00
IUUC-Afl-008419	Aspergillus flavus	50.30	6.00e-87	314.00
IUUC-Afu-008751	Aspergillus fumigatus	52.43	3.00e-86	311.00
IUUC-Ani-009181	Aspergillus nidulans	56.46	2.00e-89	322.00
IUUC-Ang-009787	Aspergillus niger	59.16	4.00e-87	314.00
IUUC-Aor-009980	Aspergillus oryzae	50.30	6.00e-87	314.00
IUUC-Ate-010286	Aspergillus terreus	49.13	3.00e-88	318.00
IUUC-Ame-010849	Astyanax mexicanus	60.88	3.00e-128	451.00
IUUC-Bgr-012110	Blumeria graminis	60.69	2.00e-87	316.00
IUUC-Bta-013474	Bos taurus	69.43	4.00e-149	520.00
IUUC-Bci-013756	Botrytis cinerea	56.19	8.00e-95	340.00
IUUC-Bdi-014257	Brachypodium distachyon	64.91	6.00e-109	386.00
IUUC-Bol-016310	Brassica oleracea	63.16	4.00e-105	374.00
IUUC-Bra-017438	Brassica rapa	63.86	1.00e-107	382.00
IUUC-Cel-018157	Caenorhabditis elegans	62.21	6.00e-100	356.00
IUUC-Cja-019282	Callithrix jacchus	68.29	1.00e-144	505.00
IUUC-Cfa-020162	Canis familiaris	67.40	7.00e-149	519.00
IUUC-Cpo-021764	Cavia porcellus	67.36	1.00e-143	502.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	64.54	6.00e-110	390.00
IUUC-Csa-023694	Chlorocebus sabaeus	68.65	2.00e-143	501.00
IUUC-Cho-024350	Choloepus hoffmanni	84.18	3.00e-98	350.00
IUUC-Cin-025542	Ciona intestinalis	75.19	8.00e-122	429.00
IUUC-Csv-025873	Ciona savignyi	73.61	1.00e-122	432.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	56.70	6.00e-81	294.00
IUUC-Cne-026928	Cryptococcus neoformans	61.87	2.00e-95	342.00
IUUC-Cme-027336	Cyanidioschyzon merolae	71.64	1.00e-120	426.00
IUUC-Dre-028198	Danio rerio	60.88	3.00e-132	464.00
IUUC-Dno-029928	Dasypus novemcinctus	68.06	1.00e-144	505.00
IUUC-Dor-030238	Dipodomys ordii	61.35	4.00e-129	454.00
IUUC-Dse-031266	Dothistroma septosporum	50.29	7.00e-92	330.00
IUUC-Dme-032007	Drosophila melanogaster	64.23	8.00e-104	370.00
IUUC-Ete-032911	Echinops telfairi	53.08	1.00e-99	355.00
IUUC-Eca-033749	Equus caballus	69.47	9.00e-148	516.00
IUUC-Eeu-035170	Erinaceus europaeus	65.91	2.00e-142	498.00
IUUC-Fca-035498	Felis catus	70.57	2.00e-151	528.00
IUUC-Fal-037397	Ficedula albicollis	69.04	4.00e-151	527.00
IUUC-Fox-037747	Fusarium oxysporum	54.27	3.00e-93	335.00
IUUC-Fso-038429	Fusarium solani	59.16	1.00e-87	316.00
IUUC-Gmo-039378	Gadus morhua	60.61	2.00e-131	461.00
IUUC-Ggr-039939	Gaeumannomyces graminis	62.60	4.00e-95	341.00
IUUC-Gga-040187	Gallus gallus	69.53	5.00e-154	536.00
IUUC-Gac-042223	Gasterosteus aculeatus	59.61	4.00e-132	464.00
IUUC-Gma-042870	Glycine max	62.59	2.00e-100	358.00
IUUC-Ggo-045617	Gorilla gorilla	67.08	2.00e-148	518.00
IUUC-Hsa-046968	Homo sapiens	66.50	2.00e-148	518.00
IUUC-Hvu-047072	Hordeum vulgare	54.01	2.00e-80	291.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	57.48	4.00e-114	404.00
IUUC-Kpa-049093	Komagataella pastoris	55.73	2.00e-75	275.00
IUUC-Lch-050346	Latimeria chalumnae	70.42	5.00e-142	496.00
IUUC-Lpe-051466	Leersia perrieri	68.42	9.00e-109	385.00
IUUC-Lma-053006	Leptosphaeria maculans	60.69	3.00e-89	322.00
IUUC-Laf-053422	Loxodonta africana	67.88	3.00e-145	507.00
IUUC-Mcc-055245	Macaca mulatta	68.92	1.00e-143	502.00
IUUC-Mor-056952	Magnaporthe oryzae	60.69	1.00e-91	329.00
IUUC-Mpo-057605	Magnaporthe poae	61.11	2.00e-95	342.00
IUUC-Mtr-057726	Medicago truncatula	65.20	7.00e-107	379.00
IUUC-Mla-059174	Melampsora laricipopulina	64.09	7.00e-100	357.00
IUUC-Mga-059562	Meleagris gallopavo	56.72	1.00e-116	412.00
IUUC-Mvi-060305	Microbotryum violaceum	62.21	1.00e-92	333.00
IUUC-Mmr-061588	Microcebus murinus	67.88	6.00e-147	513.00
IUUC-Mdo-061914	Monodelphis domestica	69.63	3.00e-155	540.00
IUUC-Mmu-063288	Mus musculus	65.91	6.00e-143	499.00
IUUC-Mac-064969	Musa acuminata	64.56	1.00e-108	385.00
IUUC-Mpu-066855	Mustela putorius furo	66.58	6.00e-148	516.00
IUUC-Mlu-068046	Myotis lucifugus	65.69	5.00e-147	513.00
IUUC-Nfi-068527	Neosartorya fischeri	58.78	2.00e-86	312.00
IUUC-Ncr-068678	Neurospora crassa	62.36	5.00e-93	334.00
IUUC-Nle-069848	Nomascus leucogenys	66.01	3.00e-147	514.00
IUUC-Opr-070589	Ochotona princeps	65.49	5.00e-142	497.00
IUUC-Ont-071733	Oreochromis niloticus	62.20	1.00e-125	442.00
IUUC-Oan-073399	Ornithorhynchus anatinus	83.22	3.00e-145	507.00
IUUC-Ocu-074063	Oryctolagus cuniculus	67.98	1.00e-152	532.00
IUUC-Oba-075264	Oryza barthii	65.26	1.00e-108	385.00
IUUC-Obr-076048	Oryza brachyantha	65.48	2.00e-107	381.00
IUUC-Ogl-077637	Oryza glaberrima	65.83	9.00e-108	382.00
IUUC-Ogu-078830	Oryza glumaepatula	65.26	1.00e-108	385.00
IUUC-Oin-079150	Oryza indica	65.26	9.00e-109	385.00
IUUC-Olo-080398	Oryza longistaminata	57.48	1.00e-83	302.00
IUUC-Ome-081544	Oryza meridionalis	56.98	2.00e-90	325.00
IUUC-Oni-082250	Oryza nivara	65.26	9.00e-109	385.00
IUUC-Opu-083638	Oryza punctata	65.26	2.00e-108	384.00
IUUC-Oru-084981	Oryza rufipogon	65.26	8.00e-109	386.00
IUUC-Osa-085961	Oryza sativa	65.26	8.00e-109	386.00
IUUC-Olu-087880	Ostreococcus lucimarinus	68.94	1.00e-111	395.00
IUUC-Oga-088891	Otolemur garnettii	66.26	2.00e-148	518.00
IUUC-Oar-090021	Ovis aries	66.67	1.00e-148	519.00
IUUC-Ptr-091458	Pan troglodytes	66.75	1.00e-148	519.00
IUUC-Pan-092546	Papio anubis	69.19	4.00e-144	504.00
IUUC-Psi-093280	Pelodiscus sinensis	71.78	8.00e-162	562.00
IUUC-Pma-094298	Petromyzon marinus	82.44	4.00e-125	440.00
IUUC-Pno-094847	Phaeosphaeria nodorum	51.04	7.00e-89	320.00
IUUC-Ppa-095855	Physcomitrella patens	66.17	5.00e-109	386.00
IUUC-Pfo-096428	Poecilia formosa	64.38	1.00e-133	469.00
IUUC-Pab-098696	Pongo abelii	66.32	7.00e-147	513.00
IUUC-Pop-099405	Populus trichocarpa	62.98	1.00e-107	382.00
IUUC-Pca-100740	Procavia capensis	65.63	2.00e-143	501.00
IUUC-Ppe-101854	Prunus persica	64.31	8.00e-109	386.00
IUUC-Pva-103212	Pteropus vampyrus	68.09	3.00e-145	507.00
IUUC-Pgr-103474	Puccinia graminis	63.88	6.00e-100	357.00
IUUC-Ptt-103933	Puccinia triticina	49.42	6.00e-63	234.00
IUUC-Pte-104089	Pyrenophora teres	60.31	1.00e-88	319.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	60.31	1.00e-88	320.00
IUUC-Rno-105057	Rattus norvegicus	66.25	6.00e-144	503.00
IUUC-Sha-107137	Sarcophilus harrisii	68.40	8.00e-153	533.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	61.78	3.00e-98	351.00
IUUC-Spo-108078	Schizosaccharomyces pombe	62.55	1.00e-99	355.00
IUUC-Smo-109288	Selaginella moellendorffii	64.86	5.00e-109	387.00
IUUC-Sit-110246	Setaria italica	65.03	3.00e-108	384.00
IUUC-Sly-111379	Solanum lycopersicum	64.73	2.00e-107	381.00
IUUC-Stu-112777	Solanum tuberosum	61.36	2.00e-107	381.00
IUUC-Sbi-114325	Sorghum bicolor	64.77	5.00e-108	383.00
IUUC-Sre-115203	Sporisorium reilianum	58.30	5.00e-80	291.00
IUUC-Ssc-115361	Sus scrofa	69.01	1.00e-148	518.00
IUUC-Tgu-116967	Taeniopygia guttata	68.87	5.00e-150	523.00
IUUC-Tru-117570	Takifugu rubripes	62.08	1.00e-132	466.00
IUUC-Tsy-119280	Tarsius syrichta	81.91	5.00e-99	354.00
IUUC-Tni-120721	Tetraodon nigroviridis	64.47	2.00e-134	471.00
IUUC-Tca-121494	Theobroma cacao	65.31	2.00e-106	378.00
IUUC-Tre-121869	Trichoderma reesei	63.12	8.00e-94	337.00
IUUC-Tvi-122510	Trichoderma virens	63.12	6.00e-93	333.00
IUUC-Tae-123071	Triticum aestivum	65.25	1.00e-108	385.00
IUUC-Tur-126240	Triticum urartu	65.25	2.00e-108	384.00
IUUC-Tme-126921	Tuber melanosporum	60.29	5.00e-95	341.00
IUUC-Tbe-127872	Tupaia belangeri	63.71	2.00e-130	458.00
IUUC-Ttr-129134	Tursiops truncatus	70.16	5.00e-145	506.00
IUUC-Uma-129412	Ustilago maydis	59.70	2.00e-77	283.00
IUUC-Vda-130003	Verticillium dahliae	49.71	2.00e-91	329.00
IUUC-Vvi-131272	Vitis vinifera	63.60	2.00e-107	381.00
IUUC-Xtr-132019	Xenopus tropicalis	61.48	7.00e-146	509.00
IUUC-Xma-134203	Xiphophorus maculatus	64.06	2.00e-138	485.00
IUUC-Yli-134503	Yarrowia lipolytica	47.09	9.00e-89	320.00
IUUC-Zma-135232	Zea mays	63.99	1.00e-106	379.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence