iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033937

Ensembl Protein ID

ENSECAP00000016024.1

UniProt Accession

F7ASY5; F7ASY5_HORSE

Protein Name

Uncharacterized protein

Gene Name

VPS36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018146.1	ENSECAT00000019570.1	ENSECAP00000016024.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/PH/GLUE	2.50e-56	189.7	1	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/PH/GLUE

   S: 33   ikfdaGellLtthRLiWirdqkneevtlaipLsavvfieeeaaaigksakivvhlhparsdkePGpldsskasyiklsfkekgdiefys 121
           ikfdaG+llL+thRLiW rdqkn+e+++ai+Ls++vfiee+aa+igksakivvhlhpa+++kePGp++ss++syiklsfke+g+iefy+
   Q: 1    IKFDAGTLLLSTHRLIW-RDQKNHECCMAILLSQIVFIEEQAAGIGKSAKIVVHLHPAPPNKEPGPFQSSRNSYIKLSFKEHGQIEFYR 88
           69***************.*********************************************************************** PP
   S: 122  kLseeltaRaWeelevse 139
           +Lsee+t+R+We+++vs+
   Q: 89   RLSEEMTQRRWENMPVSQ 106
           ****************97 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

IKFDAGTLLL STHRLIWRDQ KNHECCMAIL LSQIVFIEEQ AAGIGKSAKI VVHLHPAPPN 60
KEPGPFQSSR NSYIKLSFKE HGQIEFYRRL SEEMTQRRWE NMPVSQSLQT NRGPQPGRIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATAAAATT TGATGCTGGG ACCCTCCTTC TCAGTACACA CCGACTAATT TGGAGAGATC 60
AGAAAAATCA TGTAAGACAG AGTTTTTGCA TCTGTTCTAG GTTTTAAATC GCTGAAGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007286--EAP30
IPR021648--GLUE_dom
IPR011993--PH_dom-like
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS51495--GLUE

Pfam

PF04157--EAP30
PF11605--Vps36_ESCRT-II

Gene Ontology

GO:0005829--C:cytosol
GO:0000814--C:ESCRT II complex
GO:0070062--C:extracellular exosome
GO:0031902--C:late endosome membrane
GO:0005764--C:lysosome
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0043130--F:ubiquitin binding
GO:0043328--P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000963	Aegilops tauschii	39.79	2.00e-32	132.00
IUUC-Aml-002313	Ailuropoda melanoleuca	96.89	0.00e+00	681.00
IUUC-Atr-003096	Amborella trichopoda	36.05	1.00e-15	76.60
IUUC-Apl-003218	Anas platyrhynchos	87.85	0.00e+00	627.00
IUUC-Aca-004580	Anolis carolinensis	90.11	0.00e+00	637.00
IUUC-Aly-006398	Arabidopsis lyrata	36.73	3.00e-54	205.00
IUUC-Ath-006907	Arabidopsis thaliana	36.56	2.00e-54	206.00
IUUC-Ago-007840	Ashbya gossypii	20.52	2.00e-03	37.00
IUUC-Acl-008117	Aspergillus clavatus	31.68	4.00e-36	145.00
IUUC-Afl-008595	Aspergillus flavus	31.19	8.00e-36	145.00
IUUC-Afu-008918	Aspergillus fumigatus	30.67	5.00e-36	145.00
IUUC-Ani-009206	Aspergillus nidulans	32.74	9.00e-37	148.00
IUUC-Ang-009784	Aspergillus niger	31.69	3.00e-33	136.00
IUUC-Aor-010126	Aspergillus oryzae	31.19	7.00e-36	145.00
IUUC-Ate-010303	Aspergillus terreus	32.19	2.00e-34	140.00
IUUC-Ame-011190	Astyanax mexicanus	84.53	1.00e-172	598.00
IUUC-Bgr-011979	Blumeria graminis	30.77	3.00e-33	136.00
IUUC-Bta-012661	Bos taurus	96.89	0.00e+00	679.00
IUUC-Bci-013982	Botrytis cinerea	32.61	2.00e-33	137.00
IUUC-Bdi-014753	Brachypodium distachyon	38.46	2.00e-48	186.00
IUUC-Bol-015465	Brassica oleracea	40.31	1.00e-46	180.00
IUUC-Bra-016794	Brassica rapa	40.77	8.00e-48	184.00
IUUC-Cel-018514	Caenorhabditis elegans	42.17	2.00e-77	282.00
IUUC-Cja-019285	Callithrix jacchus	96.61	0.00e+00	679.00
IUUC-Cfa-020746	Canis familiaris	97.46	0.00e+00	685.00
IUUC-Cpo-022005	Cavia porcellus	95.76	0.00e+00	679.00
IUUC-Cre-022686	Chlamydomonas reinhardtii	35.63	5.00e-33	135.00
IUUC-Csa-023520	Chlorocebus sabaeus	97.46	0.00e+00	690.00
IUUC-Cho-024957	Choloepus hoffmanni	96.05	0.00e+00	674.00
IUUC-Csv-025942	Ciona savignyi	52.27	3.00e-95	341.00
IUUC-Cgl-026558	Colletotrichum gloeosporioides	31.85	3.00e-31	130.00
IUUC-Cne-026915	Cryptococcus neoformans	28.66	1.00e-24	107.00
IUUC-Cme-027099	Cyanidioschyzon merolae	25.11	7.00e-12	65.50
IUUC-Dre-027753	Danio rerio	83.95	7.00e-172	596.00
IUUC-Dno-029922	Dasypus novemcinctus	95.48	0.00e+00	672.00
IUUC-Dor-030643	Dipodomys ordii	87.85	8.00e-176	609.00
IUUC-Dse-031368	Dothistroma septosporum	31.46	6.00e-30	125.00
IUUC-Dme-031977	Drosophila melanogaster	45.21	2.00e-83	302.00
IUUC-Ete-033135	Echinops telfairi	72.80	3.00e-138	484.00
IUUC-Eeu-034483	Erinaceus europaeus	91.24	0.00e+00	666.00
IUUC-Fca-035496	Felis catus	96.89	0.00e+00	681.00
IUUC-Fal-036743	Ficedula albicollis	89.27	0.00e+00	637.00
IUUC-Fox-037685	Fusarium oxysporum	34.36	7.00e-27	115.00
IUUC-Fso-038421	Fusarium solani	30.85	1.00e-28	120.00
IUUC-Gmo-039456	Gadus morhua	78.57	3.00e-156	544.00
IUUC-Ggr-039763	Gaeumannomyces graminis	33.12	5.00e-37	149.00
IUUC-Gga-040556	Gallus gallus	88.42	0.00e+00	628.00
IUUC-Gac-041481	Gasterosteus aculeatus	79.77	1.00e-139	489.00
IUUC-Gma-044185	Glycine max	41.80	2.00e-50	192.00
IUUC-Ggo-044849	Gorilla gorilla	97.74	0.00e+00	691.00
IUUC-Hsa-046228	Homo sapiens	97.74	0.00e+00	691.00
IUUC-Hvu-047858	Hordeum vulgare	38.68	2.00e-13	69.30
IUUC-Itr-048692	Ictidomys tridecemlineatus	95.76	0.00e+00	679.00
IUUC-Kpa-049240	Komagataella pastoris	24.77	5.00e-06	45.80
IUUC-Lch-050293	Latimeria chalumnae	85.82	2.00e-123	434.00
IUUC-Lpe-051363	Leersia perrieri	43.44	3.00e-49	189.00
IUUC-Loc-052866	Lepisosteus oculatus	83.29	1.00e-164	572.00
IUUC-Lma-053139	Leptosphaeria maculans	31.18	4.00e-32	132.00
IUUC-Laf-053881	Loxodonta africana	89.27	2.00e-180	624.00
IUUC-Mcc-055158	Macaca mulatta	97.46	0.00e+00	690.00
IUUC-Meu-056126	Macropus eugenii	74.01	1.00e-135	475.00
IUUC-Mor-057092	Magnaporthe oryzae	30.95	7.00e-34	138.00
IUUC-Mpo-057629	Magnaporthe poae	31.88	6.00e-29	121.00
IUUC-Mtr-058039	Medicago truncatula	42.39	7.00e-51	194.00
IUUC-Mla-058913	Melampsora laricipopulina	30.23	2.00e-23	103.00
IUUC-Mga-059956	Meleagris gallopavo	88.42	0.00e+00	630.00
IUUC-Mvi-060570	Microbotryum violaceum	23.85	1.00e-17	85.10
IUUC-Mmr-061769	Microcebus murinus	96.89	0.00e+00	682.00
IUUC-Mdo-062751	Monodelphis domestica	89.50	0.00e+00	635.00
IUUC-Mmu-063115	Mus musculus	94.35	0.00e+00	670.00
IUUC-Mac-064979	Musa acuminata	35.04	2.00e-51	196.00
IUUC-Mpu-066904	Mustela putorius furo	98.73	2.00e-139	488.00
IUUC-Mlu-067474	Myotis lucifugus	96.61	0.00e+00	678.00
IUUC-Nfi-068588	Neosartorya fischeri	31.17	4.00e-33	135.00
IUUC-Ncr-068855	Neurospora crassa	29.71	3.00e-28	120.00
IUUC-Nle-069660	Nomascus leucogenys	97.18	0.00e+00	687.00
IUUC-Opr-070695	Ochotona princeps	94.63	0.00e+00	666.00
IUUC-Ont-071837	Oreochromis niloticus	83.09	3.00e-155	540.00
IUUC-Oan-072903	Ornithorhynchus anatinus	92.37	0.00e+00	654.00
IUUC-Ocu-074833	Oryctolagus cuniculus	95.48	0.00e+00	678.00
IUUC-Oba-075899	Oryza barthii	43.75	2.00e-49	188.00
IUUC-Obr-076125	Oryza brachyantha	34.93	4.00e-53	201.00
IUUC-Ogl-077538	Oryza glaberrima	47.14	6.00e-30	124.00
IUUC-Ogu-078272	Oryza glumaepatula	43.44	2.00e-49	189.00
IUUC-Oin-079158	Oryza indica	42.68	9.00e-49	187.00
IUUC-Olo-080496	Oryza longistaminata	42.50	1.00e-45	176.00
IUUC-Ome-081440	Oryza meridionalis	43.51	2.00e-47	182.00
IUUC-Oni-083069	Oryza nivara	42.68	9.00e-49	187.00
IUUC-Opu-083838	Oryza punctata	43.83	1.00e-47	183.00
IUUC-Oru-084377	Oryza rufipogon	43.44	2.00e-49	189.00
IUUC-Osa-085976	Oryza sativa	43.44	2.00e-49	189.00
IUUC-Ola-086431	Oryzias latipes	84.24	2.00e-157	548.00
IUUC-Olu-087789	Ostreococcus lucimarinus	38.43	4.00e-38	150.00
IUUC-Oga-089152	Otolemur garnettii	95.20	0.00e+00	672.00
IUUC-Oar-089198	Ovis aries	96.89	0.00e+00	680.00
IUUC-Ptr-091123	Pan troglodytes	97.74	0.00e+00	691.00
IUUC-Pan-092866	Papio anubis	93.52	0.00e+00	659.00
IUUC-Psi-093384	Pelodiscus sinensis	92.94	0.00e+00	656.00
IUUC-Pno-094773	Phaeosphaeria nodorum	30.49	3.00e-27	116.00
IUUC-Ppa-095753	Physcomitrella patens	36.22	3.00e-54	205.00
IUUC-Pfo-096028	Poecilia formosa	83.38	4.00e-157	547.00
IUUC-Pop-098915	Populus trichocarpa	42.80	9.00e-50	191.00
IUUC-Pca-100422	Procavia capensis	92.37	0.00e+00	649.00
IUUC-Ppe-101564	Prunus persica	42.86	3.00e-51	196.00
IUUC-Pva-103019	Pteropus vampyrus	90.68	0.00e+00	629.00
IUUC-Pgr-103670	Puccinia graminis	27.76	3.00e-20	93.60
IUUC-Ptt-103958	Puccinia triticina	26.61	4.00e-19	89.00
IUUC-Pte-104343	Pyrenophora teres	31.29	7.00e-38	152.00
IUUC-Pyt-104554	Pyrenophora triticirepentis	31.13	2.00e-39	157.00
IUUC-Rno-105775	Rattus norvegicus	94.63	0.00e+00	670.00
IUUC-Sce-106148	Saccharomyces cerevisiae	21.46	3.00e-03	37.00
IUUC-Sha-106468	Sarcophilus harrisii	91.81	0.00e+00	647.00
IUUC-Sja-107850	Schizosaccharomyces japonicus	22.88	1.00e-15	77.40
IUUC-Spo-108225	Schizosaccharomyces pombe	23.79	3.00e-17	83.20
IUUC-Ssl-108412	Sclerotinia sclerotiorum	32.06	8.00e-31	128.00
IUUC-Smo-109001	Selaginella moellendorffii	35.01	2.00e-52	199.00
IUUC-Sit-110126	Setaria italica	38.38	3.00e-46	179.00
IUUC-Sly-110884	Solanum lycopersicum	35.01	3.00e-49	189.00
IUUC-Stu-112573	Solanum tuberosum	34.56	1.00e-49	190.00
IUUC-Sar-113114	Sorex araneus	95.52	1.00e-71	262.00
IUUC-Sbi-114331	Sorghum bicolor	29.04	3.00e-35	142.00
IUUC-Sre-115135	Sporisorium reilianum	23.01	1.00e-09	58.20
IUUC-Ssc-116158	Sus scrofa	97.46	0.00e+00	686.00
IUUC-Tgu-116962	Taeniopygia guttata	88.98	0.00e+00	632.00
IUUC-Tru-117567	Takifugu rubripes	82.81	2.00e-156	544.00
IUUC-Tsy-119357	Tarsius syrichta	85.31	3.00e-163	567.00
IUUC-Tni-120047	Tetraodon nigroviridis	82.23	8.00e-154	536.00
IUUC-Tca-121097	Theobroma cacao	42.80	2.00e-51	196.00
IUUC-Tre-122075	Trichoderma reesei	29.78	6.00e-34	139.00
IUUC-Tvi-122623	Trichoderma virens	31.75	5.00e-40	159.00
IUUC-Tae-123728	Triticum aestivum	41.39	3.00e-48	186.00
IUUC-Tur-125988	Triticum urartu	40.31	2.00e-38	152.00
IUUC-Tme-126936	Tuber melanosporum	30.79	3.00e-34	140.00
IUUC-Tbe-127481	Tupaia belangeri	66.67	4.00e-126	444.00
IUUC-Ttr-128160	Tursiops truncatus	96.89	0.00e+00	681.00
IUUC-Uma-129428	Ustilago maydis	25.90	7.00e-17	82.40
IUUC-Vda-129877	Verticillium dahliae	31.23	9.00e-30	125.00
IUUC-Vpa-130358	Vicugna pacos	96.89	0.00e+00	676.00
IUUC-Vvi-131406	Vitis vinifera	35.90	7.00e-55	207.00
IUUC-Xtr-132548	Xenopus tropicalis	85.31	7.00e-171	592.00
IUUC-Xma-133352	Xiphophorus maculatus	83.67	2.00e-157	548.00
IUUC-Yli-134466	Yarrowia lipolytica	31.22	7.00e-21	95.10
IUUC-Zma-135081	Zea mays	38.73	3.00e-48	185.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence