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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Spo-108258
Ensembl Protein ID SPAC16C9.06c.1:pep
UniProt Accession Q09820; RENT1_SCHPO
Genbank Protein ID CAA91194.2
Protein Name ATP-dependent helicase upf1; Nonsense-mediated mRNA decay protein upf1; Regulator of nonsense transcripts 1 homolog; Up-frameshift suppressor 1
Genbank Nucleotide ID CU329670
Gene Name upf1; SPAC16C9.06c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPAC16C9.06c SPAC16C9.06c.1 SPAC16C9.06c.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFdbPTM
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/Other 55.92 0.00e+00 948.00 IUUC-Sce-106206
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Required for rapid turnover of mRNAs containing a premature translational termination codon.
 Required for rapid turnover of mRNAs containing a premature translational termination codon.
Protein Sequence
(Fasta)
MSLGLQPNND ISSLVSSKNM TSENGLEHQF EELLVEKQYS EEHCAYCHIK NPNSILKCLH 60
CNKWFCNVRG KSGASHIISH LVRARHKQVA LHSHSSLSDT VLECYNCGTR NVFLLGFIPA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108258|E3,E3 activity/Other|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AATTGACGGC TTAATAACAT ATCAAGTTGT CTTTCCATGT CTTTAGGGCT ACAACCTAAT 60
AATGATATTT CATCTTTAGT TAGTTCAAAA AATATGACTT CTGAAAATGG ACTAGAGCAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108258|E3,E3 activity/Other|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0866--Nonsense-mediated mRNA decay
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003593--AAA+_ATPase
IPR027417--P-loop_NTPase
IPR018999--RNA-helicase_UPF1_UPF2-interct
Pfam

PF09416--UPF1_Zn_bind
SMART

SM00382--AAA
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005524--F:ATP binding
GO:0004004--F:ATP-dependent RNA helicase activity
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding
GO:0070478--P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
GO:2000815--P:regulation of mRNA stability involved in response to oxidative stress
KEGG spo:SPAC16C9.06c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000680 Aegilops tauschii 59.57 0.00e+00 940.00
IUUC-Aml-002008 Ailuropoda melanoleuca 60.52 0.00e+00 1047.00
IUUC-Atr-002632 Amborella trichopoda 57.96 0.00e+00 989.00
IUUC-Apl-003997 Anas platyrhynchos 60.52 0.00e+00 1046.00
IUUC-Aca-004322 Anolis carolinensis 32.95 6.00e-52 197.00
IUUC-Aly-006521 Arabidopsis lyrata 58.44 0.00e+00 984.00
IUUC-Ath-007059 Arabidopsis thaliana 58.69 0.00e+00 989.00
IUUC-Ago-007801 Ashbya gossypii 56.22 0.00e+00 925.00
IUUC-Acl-008312 Aspergillus clavatus 61.25 0.00e+00 1097.00
IUUC-Afl-008429 Aspergillus flavus 61.51 0.00e+00 1093.00
IUUC-Afu-009092 Aspergillus fumigatus 61.77 0.00e+00 1094.00
IUUC-Ani-009317 Aspergillus nidulans 62.14 0.00e+00 1097.00
IUUC-Ang-009783 Aspergillus niger 60.96 0.00e+00 1097.00
IUUC-Aor-010178 Aspergillus oryzae 61.51 0.00e+00 1093.00
IUUC-Ate-010294 Aspergillus terreus 60.92 0.00e+00 1098.00
IUUC-Ame-010774 Astyanax mexicanus 61.30 1.00e-104 372.00
IUUC-Bgr-012293 Blumeria graminis 61.58 0.00e+00 1094.00
IUUC-Bta-012382 Bos taurus 60.52 0.00e+00 1047.00
IUUC-Bci-013937 Botrytis cinerea 60.68 0.00e+00 1091.00
IUUC-Bdi-014612 Brachypodium distachyon 59.76 0.00e+00 998.00
IUUC-Bol-015145 Brassica oleracea 57.28 0.00e+00 980.00
IUUC-Bra-017370 Brassica rapa 56.24 0.00e+00 956.00
IUUC-Cel-018240 Caenorhabditis elegans 51.63 0.00e+00 855.00
IUUC-Cja-019892 Callithrix jacchus 61.15 0.00e+00 1048.00
IUUC-Cfa-020700 Canis familiaris 60.52 0.00e+00 1047.00
IUUC-Cpo-021510 Cavia porcellus 60.64 0.00e+00 1050.00
IUUC-Cre-022731 Chlamydomonas reinhardtii 52.97 0.00e+00 846.00
IUUC-Csa-023665 Chlorocebus sabaeus 61.15 0.00e+00 1050.00
IUUC-Cho-025098 Choloepus hoffmanni 26.37 8.70e-02 29.60
IUUC-Cin-025798 Ciona intestinalis 60.29 0.00e+00 966.00
IUUC-Csv-025901 Ciona savignyi 58.07 0.00e+00 974.00
IUUC-Cgl-026653 Colletotrichum gloeosporioides 61.50 0.00e+00 1070.00
IUUC-Cne-027014 Cryptococcus neoformans 61.00 0.00e+00 1125.00
IUUC-Dre-028705 Danio rerio 59.62 0.00e+00 1052.00
IUUC-Dor-030369 Dipodomys ordii 59.28 0.00e+00 1005.00
IUUC-Dme-031767 Drosophila melanogaster 56.64 0.00e+00 995.00
IUUC-Ete-032800 Echinops telfairi 32.18 1.00e-50 192.00
IUUC-Eca-033840 Equus caballus 61.15 0.00e+00 1048.00
IUUC-Fca-035466 Felis catus 60.44 0.00e+00 1046.00
IUUC-Fal-037548 Ficedula albicollis 60.99 0.00e+00 1042.00
IUUC-Fox-038023 Fusarium oxysporum 60.37 0.00e+00 1056.00
IUUC-Gmo-039285 Gadus morhua 60.44 0.00e+00 1039.00
IUUC-Ggr-039810 Gaeumannomyces graminis 60.91 0.00e+00 1085.00
IUUC-Gga-040972 Gallus gallus 61.15 0.00e+00 1048.00
IUUC-Gac-042075 Gasterosteus aculeatus 60.49 0.00e+00 1040.00
IUUC-Gma-042713 Glycine max 59.04 0.00e+00 1019.00
IUUC-Ggo-045398 Gorilla gorilla 61.15 0.00e+00 1047.00
IUUC-Hsa-046152 Homo sapiens 61.15 0.00e+00 1050.00
IUUC-Hvu-047555 Hordeum vulgare 57.06 7.00e-155 538.00
IUUC-Itr-048247 Ictidomys tridecemlineatus 60.54 0.00e+00 1042.00
IUUC-Kpa-049205 Komagataella pastoris 49.22 0.00e+00 758.00
IUUC-Lch-049587 Latimeria chalumnae 63.55 0.00e+00 674.00
IUUC-Lpe-051059 Leersia perrieri 59.63 0.00e+00 997.00
IUUC-Loc-051911 Lepisosteus oculatus 61.15 0.00e+00 1046.00
IUUC-Lma-053007 Leptosphaeria maculans 64.22 0.00e+00 1105.00
IUUC-Laf-054234 Loxodonta africana 60.52 0.00e+00 1048.00
IUUC-Mcc-054762 Macaca mulatta 60.52 0.00e+00 1048.00
IUUC-Meu-056677 Macropus eugenii 63.43 1.00e-115 409.00
IUUC-Mor-057147 Magnaporthe oryzae 61.27 0.00e+00 1087.00
IUUC-Mpo-057314 Magnaporthe poae 60.91 0.00e+00 1085.00
IUUC-Mtr-058329 Medicago truncatula 59.04 0.00e+00 1019.00
IUUC-Mla-059094 Melampsora laricipopulina 56.70 4.00e-167 579.00
IUUC-Mga-060126 Meleagris gallopavo 60.20 0.00e+00 1036.00
IUUC-Mvi-060373 Microbotryum violaceum 61.17 0.00e+00 1134.00
IUUC-Mmr-060628 Microcebus murinus 60.52 0.00e+00 1048.00
IUUC-Mdo-061858 Monodelphis domestica 61.15 0.00e+00 1048.00
IUUC-Mmu-064116 Mus musculus 61.15 0.00e+00 1049.00
IUUC-Mac-065136 Musa acuminata 59.41 0.00e+00 998.00
IUUC-Mpu-066463 Mustela putorius furo 61.15 0.00e+00 1050.00
IUUC-Mlu-068098 Myotis lucifugus 61.15 0.00e+00 1049.00
IUUC-Nfi-068370 Neosartorya fischeri 61.77 0.00e+00 1094.00
IUUC-Ncr-068792 Neurospora crassa 61.80 0.00e+00 1092.00
IUUC-Nle-070102 Nomascus leucogenys 61.15 0.00e+00 1045.00
IUUC-Opr-070620 Ochotona princeps 57.91 0.00e+00 961.00
IUUC-Ont-072685 Oreochromis niloticus 61.27 0.00e+00 1049.00
IUUC-Oan-073665 Ornithorhynchus anatinus 58.68 0.00e+00 1046.00
IUUC-Ocu-074154 Oryctolagus cuniculus 31.24 2.00e-52 199.00
IUUC-Oba-075075 Oryza barthii 57.42 0.00e+00 804.00
IUUC-Obr-076183 Oryza brachyantha 59.80 0.00e+00 860.00
IUUC-Ogl-077691 Oryza glaberrima 59.78 0.00e+00 996.00
IUUC-Ogu-078423 Oryza glumaepatula 59.63 0.00e+00 996.00
IUUC-Oin-080107 Oryza indica 59.63 0.00e+00 996.00
IUUC-Olo-080269 Oryza longistaminata 60.31 0.00e+00 947.00
IUUC-Ome-081779 Oryza meridionalis 59.63 0.00e+00 995.00
IUUC-Oni-082366 Oryza nivara 59.63 0.00e+00 996.00
IUUC-Opu-083958 Oryza punctata 59.63 0.00e+00 998.00
IUUC-Oru-084182 Oryza rufipogon 59.63 0.00e+00 996.00
IUUC-Osa-085285 Oryza sativa 59.63 0.00e+00 997.00
IUUC-Ola-086954 Oryzias latipes 56.77 0.00e+00 993.00
IUUC-Olu-087685 Ostreococcus lucimarinus 53.04 0.00e+00 850.00
IUUC-Oga-088591 Otolemur garnettii 61.15 0.00e+00 1050.00
IUUC-Oar-089417 Ovis aries 60.39 0.00e+00 1045.00
IUUC-Ptr-091510 Pan troglodytes 60.27 0.00e+00 1027.00
IUUC-Pan-091886 Papio anubis 61.15 0.00e+00 1050.00
IUUC-Psi-093755 Pelodiscus sinensis 61.82 0.00e+00 744.00
IUUC-Pma-094470 Petromyzon marinus 60.28 0.00e+00 1077.00
IUUC-Pno-094963 Phaeosphaeria nodorum 64.09 0.00e+00 1104.00
IUUC-Ppa-095479 Physcomitrella patens 57.49 0.00e+00 1012.00
IUUC-Pfo-097456 Poecilia formosa 61.02 0.00e+00 1043.00
IUUC-Pab-098075 Pongo abelii 57.20 0.00e+00 954.00
IUUC-Pop-099557 Populus trichocarpa 57.89 0.00e+00 1009.00
IUUC-Pca-100717 Procavia capensis 68.24 8.00e-124 436.00
IUUC-Ppe-101675 Prunus persica 59.16 0.00e+00 1016.00
IUUC-Pva-103029 Pteropus vampyrus 61.21 0.00e+00 790.00
IUUC-Pgr-103318 Puccinia graminis 60.95 0.00e+00 1099.00
IUUC-Ptt-103956 Puccinia triticina 61.61 0.00e+00 1087.00
IUUC-Pte-104399 Pyrenophora teres 64.46 0.00e+00 1108.00
IUUC-Pyt-104749 Pyrenophora triticirepentis 64.09 0.00e+00 1105.00
IUUC-Rno-105784 Rattus norvegicus 61.15 0.00e+00 1049.00
IUUC-Sce-106206 Saccharomyces cerevisiae 53.13 0.00e+00 919.00
IUUC-Sha-106566 Sarcophilus harrisii 60.37 0.00e+00 1041.00
IUUC-Sja-107721 Schizosaccharomyces japonicus 73.11 0.00e+00 1387.00
IUUC-Ssl-108640 Sclerotinia sclerotiorum 58.99 0.00e+00 961.00
IUUC-Sit-109760 Setaria italica 60.27 0.00e+00 999.00
IUUC-Sly-111807 Solanum lycopersicum 58.19 0.00e+00 1016.00
IUUC-Stu-112869 Solanum tuberosum 55.93 0.00e+00 1013.00
IUUC-Sar-112950 Sorex araneus 34.01 9.00e-41 160.00
IUUC-Sbi-114863 Sorghum bicolor 60.00 0.00e+00 999.00
IUUC-Sre-115092 Sporisorium reilianum 64.86 0.00e+00 1130.00
IUUC-Tgu-117214 Taeniopygia guttata 55.75 0.00e+00 925.00
IUUC-Tru-118386 Takifugu rubripes 58.54 0.00e+00 1029.00
IUUC-Tsy-119550 Tarsius syrichta 56.90 4.00e-95 340.00
IUUC-Tni-120212 Tetraodon nigroviridis 60.07 0.00e+00 1015.00
IUUC-Tca-121353 Theobroma cacao 58.33 0.00e+00 1023.00
IUUC-Tre-122245 Trichoderma reesei 33.56 5.00e-53 202.00
IUUC-Tvi-122452 Trichoderma virens 60.92 0.00e+00 1063.00
IUUC-Tae-123692 Triticum aestivum 60.00 0.00e+00 998.00
IUUC-Tur-126770 Triticum urartu 50.63 0.00e+00 856.00
IUUC-Tme-126956 Tuber melanosporum 62.08 0.00e+00 1115.00
IUUC-Tbe-127873 Tupaia belangeri 30.61 3.00e-45 174.00
IUUC-Ttr-128212 Tursiops truncatus 56.91 0.00e+00 943.00
IUUC-Uma-129327 Ustilago maydis 63.51 0.00e+00 1130.00
IUUC-Vda-129858 Verticillium dahliae 60.53 0.00e+00 1074.00
IUUC-Vpa-130743 Vicugna pacos 31.26 2.00e-47 182.00
IUUC-Vvi-131222 Vitis vinifera 58.78 0.00e+00 990.00
IUUC-Xtr-131800 Xenopus tropicalis 59.73 0.00e+00 835.00
IUUC-Xma-133216 Xiphophorus maculatus 59.07 0.00e+00 1042.00
IUUC-Yli-134482 Yarrowia lipolytica 51.72 0.00e+00 880.00
IUUC-Zma-134802 Zea mays 60.00 0.00e+00 998.00
Created Date 25-Jun-2017

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