iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pyt-104757

Ensembl Protein ID

EDU41067

UniProt Accession

B2VWR7; B2VWR7_PYRTR

Genbank Protein ID

EDU41067.1

Protein Name

Ubiquitin-conjugating enzyme E2 2

Genbank Nucleotide ID

DS231615

Gene Name

PTRG_01629

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PTRG_01629	EDU41067	EDU41067

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.90e-52	176.0	8	143

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesv 101
           Rl++++k++++dpp+g+sa+p  + ++++w+++i+Gp+dtp+e+g+F+l ++f+e YP kPP+vkf++++fhPnvy +G++Cl+il+  ++Wsp+++v+ +
   Q: 8    RLMRDFKRMQTDPPAGVSASPIAD-NVMTWNAVIIGPADTPFEDGTFRLVMHFEEAYPNKPPSVKFISQMFHPNVYGTGELCLDILQ--NRWSPTYDVAAI 105
           9***********************.9************************************************************9..************ PP
   S: 102  llsiqsllaepnpesplneeaaellkknreeykkkvre 139
           l+siqsll++pn++sp+n+ea++l+k+nr+ey k+vre
   Q: 106  LTSIQSLLNDPNTSSPANVEASNLYKENRKEYTKRVRE 143
           ***********************************985 PP

Organism

Pyrenophora triticirepentis

Protein Sequence
(Fasta)

MSTAARRRLM RDFKRMQTDP PAGVSASPIA DNVMTWNAVI IGPADTPFED GTFRLVMHFE 60
EAYPNKPPSV KFISQMFHPN VYGTGELCLD ILQNRWSPTY DVAAILTSIQ SLLNDPNTSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGCATCT CAGTACAACG GCAACGTTGA TAGCCTCAAC ACGCAACACG CAGTACACAA 60
AACACAACGT ATACATCTCT ACTTGCTCCT GCTCCTGCCA CTACTTTGAC CACATACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0005829--C:cytosol
GO:0033503--C:HULC complex
GO:1990304--C:MUB1-RAD6-UBR2 ubiquitin ligase complex
GO:0000790--C:nuclear chromatin
GO:0000502--C:proteasome complex
GO:0097505--C:Rad6-Rad18 complex
GO:0005524--F:ATP binding
GO:0003697--F:single-stranded DNA binding
GO:0043142--F:single-stranded DNA-dependent ATPase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0071455--P:cellular response to hyperoxia
GO:0031497--P:chromatin assembly
GO:0006348--P:chromatin silencing at telomere
GO:0006353--P:DNA-templated transcription, termination
GO:0000724--P:double-strand break repair via homologous recombination
GO:0042275--P:error-free postreplication DNA repair
GO:0070987--P:error-free translesion synthesis
GO:0042276--P:error-prone translesion synthesis
GO:0071894--P:histone H2B conserved C-terminal lysine ubiquitination
GO:0010390--P:histone monoubiquitination
GO:0042138--P:meiotic DNA double-strand break formation
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:0061186--P:negative regulation of chromatin silencing at silent mating-type cassette
GO:0031939--P:negative regulation of chromatin silencing at telomere
GO:1901487--P:negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels
GO:0010620--P:negative regulation of transcription by transcription factor catabolism
GO:1990920--P:proteasome localization to nuclear periphery
GO:0070534--P:protein K63-linked ubiquitination
GO:1901044--P:protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process
GO:0090089--P:regulation of dipeptide transport
GO:0051569--P:regulation of histone H3-K4 methylation
GO:0000722--P:telomere maintenance via recombination
GO:0006366--P:transcription from RNA polymerase II promoter
GO:0071629--P:ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001001	Aegilops tauschii	65.10	8.00e-61	223.00
IUUC-Aml-002120	Ailuropoda melanoleuca	69.54	4.00e-65	238.00
IUUC-Atr-002862	Amborella trichopoda	66.67	3.00e-62	228.00
IUUC-Apl-004063	Anas platyrhynchos	62.16	1.00e-54	203.00
IUUC-Aca-005001	Anolis carolinensis	68.87	5.00e-65	237.00
IUUC-Aly-005584	Arabidopsis lyrata	66.44	1.00e-61	226.00
IUUC-Ath-007149	Arabidopsis thaliana	66.44	1.00e-61	226.00
IUUC-Ago-007745	Ashbya gossypii	75.33	1.00e-69	253.00
IUUC-Acl-008139	Aspergillus clavatus	96.03	4.00e-86	308.00
IUUC-Afl-008551	Aspergillus flavus	95.36	1.00e-85	306.00
IUUC-Afu-008980	Aspergillus fumigatus	95.36	1.00e-85	306.00
IUUC-Ang-009554	Aspergillus niger	95.36	1.00e-85	306.00
IUUC-Aor-010242	Aspergillus oryzae	95.36	1.00e-85	306.00
IUUC-Ate-010390	Aspergillus terreus	95.36	1.00e-85	306.00
IUUC-Ame-010743	Astyanax mexicanus	70.20	7.00e-65	237.00
IUUC-Bgr-012039	Blumeria graminis	91.18	2.00e-74	268.00
IUUC-Bta-012840	Bos taurus	69.54	4.00e-65	238.00
IUUC-Bci-013919	Botrytis cinerea	92.72	2.00e-83	299.00
IUUC-Bdi-015010	Brachypodium distachyon	67.11	9.00e-62	226.00
IUUC-Bol-016245	Brassica oleracea	66.44	8.00e-62	227.00
IUUC-Bra-018026	Brassica rapa	66.44	8.00e-62	227.00
IUUC-Cel-018244	Caenorhabditis elegans	70.47	2.00e-65	239.00
IUUC-Cja-019737	Callithrix jacchus	69.54	4.00e-65	238.00
IUUC-Cfa-020244	Canis familiaris	69.54	4.00e-65	238.00
IUUC-Cpo-022192	Cavia porcellus	69.54	4.00e-65	238.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	67.44	1.00e-51	193.00
IUUC-Csa-023430	Chlorocebus sabaeus	69.54	4.00e-65	238.00
IUUC-Cho-024773	Choloepus hoffmanni	54.97	2.00e-45	172.00
IUUC-Cin-025537	Ciona intestinalis	68.46	3.00e-53	199.00
IUUC-Csv-025846	Ciona savignyi	68.00	6.00e-57	211.00
IUUC-Cgl-026381	Colletotrichum gloeosporioides	93.38	5.00e-84	300.00
IUUC-Cne-026864	Cryptococcus neoformans	72.48	2.00e-66	242.00
IUUC-Cme-027284	Cyanidioschyzon merolae	64.00	4.00e-51	192.00
IUUC-Dre-027775	Danio rerio	69.54	5.00e-65	237.00
IUUC-Dno-029661	Dasypus novemcinctus	69.54	4.00e-65	238.00
IUUC-Dor-030452	Dipodomys ordii	66.91	1.00e-56	209.00
IUUC-Dse-031487	Dothistroma septosporum	96.69	2.00e-86	309.00
IUUC-Dme-031863	Drosophila melanogaster	70.86	1.00e-64	236.00
IUUC-Ete-032595	Echinops telfairi	67.55	2.00e-63	232.00
IUUC-Eca-033377	Equus caballus	69.54	4.00e-65	238.00
IUUC-Eeu-035191	Erinaceus europaeus	55.56	1.00e-44	170.00
IUUC-Fca-036336	Felis catus	69.54	4.00e-65	238.00
IUUC-Fal-037474	Ficedula albicollis	68.64	2.00e-49	185.00
IUUC-Fox-037808	Fusarium oxysporum	93.38	7.00e-84	300.00
IUUC-Fso-038232	Fusarium solani	92.72	2.00e-83	298.00
IUUC-Gmo-038517	Gadus morhua	69.54	1.00e-64	236.00
IUUC-Ggr-039875	Gaeumannomyces graminis	94.00	1.00e-83	299.00
IUUC-Gga-040494	Gallus gallus	69.54	4.00e-65	238.00
IUUC-Gac-042471	Gasterosteus aculeatus	69.54	4.00e-65	238.00
IUUC-Gma-044057	Glycine max	67.11	2.00e-62	229.00
IUUC-Ggo-044896	Gorilla gorilla	69.54	1.00e-64	236.00
IUUC-Hsa-046239	Homo sapiens	69.54	4.00e-65	238.00
IUUC-Hvu-047054	Hordeum vulgare	65.10	8.00e-61	223.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	69.54	4.00e-65	238.00
IUUC-Kpa-049225	Komagataella pastoris	81.21	2.00e-73	266.00
IUUC-Lch-050283	Latimeria chalumnae	68.87	8.00e-65	237.00
IUUC-Lpe-051301	Leersia perrieri	67.11	5.00e-62	228.00
IUUC-Loc-051962	Lepisosteus oculatus	70.86	8.00e-66	240.00
IUUC-Laf-053380	Loxodonta africana	69.54	4.00e-65	238.00
IUUC-Mcc-054819	Macaca mulatta	69.54	3.00e-65	238.00
IUUC-Meu-056231	Macropus eugenii	69.54	1.00e-64	236.00
IUUC-Mor-057087	Magnaporthe oryzae	93.33	2.00e-74	268.00
IUUC-Mpo-057498	Magnaporthe poae	94.00	8.00e-84	301.00
IUUC-Mtr-058612	Medicago truncatula	67.11	7.00e-54	200.00
IUUC-Mla-058876	Melampsora laricipopulina	74.17	4.00e-63	231.00
IUUC-Mga-059863	Meleagris gallopavo	67.15	3.00e-57	211.00
IUUC-Mvi-060330	Microbotryum violaceum	76.16	5.00e-63	231.00
IUUC-Mmr-060630	Microcebus murinus	69.54	4.00e-65	238.00
IUUC-Mdo-062676	Monodelphis domestica	69.54	4.00e-65	238.00
IUUC-Mmu-063491	Mus musculus	69.54	4.00e-65	238.00
IUUC-Mac-064774	Musa acuminata	67.11	5.00e-62	228.00
IUUC-Mpu-065803	Mustela putorius furo	69.54	4.00e-65	238.00
IUUC-Mlu-067147	Myotis lucifugus	69.54	4.00e-65	238.00
IUUC-Nfi-068580	Neosartorya fischeri	95.36	1.00e-85	306.00
IUUC-Ncr-068913	Neurospora crassa	93.38	7.00e-84	300.00
IUUC-Nle-070105	Nomascus leucogenys	69.54	4.00e-65	238.00
IUUC-Opr-070935	Ochotona princeps	69.54	4.00e-65	238.00
IUUC-Ont-071335	Oreochromis niloticus	69.54	5.00e-65	238.00
IUUC-Oan-072706	Ornithorhynchus anatinus	64.38	5.00e-58	214.00
IUUC-Ocu-074130	Oryctolagus cuniculus	69.54	4.00e-65	238.00
IUUC-Oba-075896	Oryza barthii	67.11	9.00e-62	226.00
IUUC-Obr-076770	Oryza brachyantha	67.79	3.00e-62	228.00
IUUC-Ogl-077116	Oryza glaberrima	67.11	5.00e-62	228.00
IUUC-Ogu-078696	Oryza glumaepatula	67.11	5.00e-62	228.00
IUUC-Oin-079099	Oryza indica	67.11	5.00e-62	228.00
IUUC-Olo-081018	Oryza longistaminata	56.36	4.00e-52	195.00
IUUC-Ome-081285	Oryza meridionalis	67.11	5.00e-62	228.00
IUUC-Oni-082088	Oryza nivara	67.11	5.00e-62	228.00
IUUC-Opu-083310	Oryza punctata	67.11	5.00e-62	228.00
IUUC-Oru-084449	Oryza rufipogon	67.11	5.00e-62	228.00
IUUC-Osa-085923	Oryza sativa	67.11	5.00e-62	228.00
IUUC-Ola-087160	Oryzias latipes	69.54	5.00e-65	238.00
IUUC-Olu-087830	Ostreococcus lucimarinus	67.11	4.00e-54	201.00
IUUC-Oga-088836	Otolemur garnettii	69.54	4.00e-65	238.00
IUUC-Oar-090141	Ovis aries	69.54	4.00e-65	238.00
IUUC-Ptr-091453	Pan troglodytes	69.54	4.00e-65	238.00
IUUC-Pan-092511	Papio anubis	69.54	4.00e-65	238.00
IUUC-Psi-093968	Pelodiscus sinensis	68.87	5.00e-65	237.00
IUUC-Pma-094376	Petromyzon marinus	69.54	3.00e-64	235.00
IUUC-Pno-094935	Phaeosphaeria nodorum	98.68	6.00e-88	313.00
IUUC-Ppa-095689	Physcomitrella patens	67.79	1.00e-52	196.00
IUUC-Pfo-096656	Poecilia formosa	68.87	1.00e-64	236.00
IUUC-Pab-098121	Pongo abelii	69.54	4.00e-65	238.00
IUUC-Pop-099734	Populus trichocarpa	67.11	4.00e-56	208.00
IUUC-Pca-100906	Procavia capensis	64.24	7.00e-58	214.00
IUUC-Ppe-101594	Prunus persica	67.11	3.00e-62	228.00
IUUC-Pva-102380	Pteropus vampyrus	68.87	2.00e-62	229.00
IUUC-Pgr-103611	Puccinia graminis	74.17	2.00e-63	232.00
IUUC-Ptt-103971	Puccinia triticina	77.12	9.00e-49	183.00
IUUC-Pte-104378	Pyrenophora teres	100.00	8.00e-89	317.00
IUUC-Rno-105772	Rattus norvegicus	69.54	3.00e-65	238.00
IUUC-Sce-106283	Saccharomyces cerevisiae	75.33	1.00e-69	253.00
IUUC-Sha-107650	Sarcophilus harrisii	68.87	9.00e-64	233.00
IUUC-Sja-107790	Schizosaccharomyces japonicus	81.33	2.00e-66	242.00
IUUC-Spo-108073	Schizosaccharomyces pombe	81.33	2.00e-66	242.00
IUUC-Ssl-108432	Sclerotinia sclerotiorum	92.72	2.00e-83	299.00
IUUC-Smo-109512	Selaginella moellendorffii	67.79	3.00e-62	228.00
IUUC-Sit-110731	Setaria italica	67.11	5.00e-62	228.00
IUUC-Sly-111506	Solanum lycopersicum	67.11	2.00e-62	229.00
IUUC-Stu-112080	Solanum tuberosum	67.11	2.00e-62	229.00
IUUC-Sar-113429	Sorex araneus	69.54	4.00e-65	238.00
IUUC-Sbi-114289	Sorghum bicolor	67.11	5.00e-62	228.00
IUUC-Sre-115106	Sporisorium reilianum	74.17	4.00e-63	231.00
IUUC-Ssc-116265	Sus scrofa	69.54	1.00e-64	236.00
IUUC-Tgu-117383	Taeniopygia guttata	69.54	1.00e-64	236.00
IUUC-Tru-118576	Takifugu rubripes	68.87	3.00e-64	234.00
IUUC-Tsy-119000	Tarsius syrichta	69.54	4.00e-65	238.00
IUUC-Tni-119745	Tetraodon nigroviridis	68.87	2.00e-64	235.00
IUUC-Tca-121827	Theobroma cacao	67.79	2.00e-62	229.00
IUUC-Tre-122002	Trichoderma reesei	93.38	1.00e-83	299.00
IUUC-Tvi-122331	Trichoderma virens	93.38	1.00e-83	299.00
IUUC-Tae-124461	Triticum aestivum	66.44	1.00e-61	227.00
IUUC-Tur-126866	Triticum urartu	65.77	3.00e-61	225.00
IUUC-Tme-127148	Tuber melanosporum	93.33	1.00e-83	299.00
IUUC-Tbe-127921	Tupaia belangeri	67.55	1.00e-60	223.00
IUUC-Ttr-129121	Tursiops truncatus	69.54	4.00e-65	238.00
IUUC-Uma-129561	Ustilago maydis	74.17	3.00e-63	232.00
IUUC-Vda-129711	Verticillium dahliae	93.38	5.00e-84	300.00
IUUC-Vpa-130570	Vicugna pacos	61.76	7.00e-51	190.00
IUUC-Vvi-131108	Vitis vinifera	67.11	2.00e-62	229.00
IUUC-Xtr-131824	Xenopus tropicalis	69.54	3.00e-65	238.00
IUUC-Xma-133667	Xiphophorus maculatus	69.54	5.00e-65	238.00
IUUC-Yli-134660	Yarrowia lipolytica	83.44	7.00e-77	277.00
IUUC-Zma-135584	Zea mays	65.77	3.00e-61	225.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence