iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aly-006529

Ensembl Protein ID

Al_scaffold_0002_1260

UniProt Accession

D7KUA4; D7KUA4_ARALL

Genbank Protein ID

EFH64786.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

GL348714

Gene Name

ARALYDRAFT_676110

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Al_scaffold_0002_1260	Al_scaffold_0002_1260	Al_scaffold_0002_1260

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	33.90	8.40e-02	32.30	IUUC-Spo-108080

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis lyrata

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAIRGGDDGE RAGDDRSLKR KRIPSQVEES EDVTATRMAT IGGNDFEDVI TEAQSGTPKS 60
TQSLKLQSSD VLDCPICYEP LKRPIYQCNN GHLACSSCCK KMNKRCSFCQ SPIGDIRCRA 120

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Nucleotide Sequence
(Fasta)

ATGGCGATAC GTGGAGGAGA CGACGGAGAA AGAGCCGGTG ACGATCGTTC CCTCAAGAGA 60
AAACGAATTC CTTCTCAAGT TGAAGAGAGC GAAGATGTTA CTGCAACGAG AATGGCGACT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR001370--BIR_rpt
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_676110

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-007199	Arabidopsis thaliana	50.93	7.00e-87	313.00
IUUC-Ang-009779	Aspergillus niger	28.78	9.00e-07	47.40
IUUC-Bra-016641	Brassica rapa	55.29	4.00e-73	267.00
IUUC-Mtr-058365	Medicago truncatula	33.58	2.00e-38	152.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence