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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Spo-108080
UUCD1 version UUC-ScP-00019
Ensembl Protein ID SPAC19A8.10.1:pep
UniProt Accession O13826; RFP1_SCHPO
Genbank Protein ID CAB11646.1
Protein Name E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1; Meiotically up-regulated gene 140 protein; RING finger protein 1; RING-type E3 ubiquitin transferase rfp1
Genbank Nucleotide ID CU329670
Gene Name rfp1; mug140; SPAC19A8.10
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPAC19A8.10 SPAC19A8.10.1 SPAC19A8.10.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexHINTMentha
Protein Expression/Proteomics
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 19923268
Classification
Family E-value Score Start End
E3 activity/RING/RING 0.0018 16.9 189 234
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING

   S: 1    CaiCledf.......kdgplvlpCgHvfhadClqkwpglknssskefrC 42
    C+ C+e++ k + + CgHv++ +C + + k s++ + +C
   Q: 189 CPRCQEPLgtskskeKSALWATKCGHVYCGSCAKVL---KTSKRSQSKC 234
    ********666554322244599*********7444...5555555556 PP
   

Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description



     Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains. Involved in maintaining genome stability where it acts in the cellular response to DNA damage. Has a role in meiosis.
Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains. Involved in maintaining genome stability where it acts in the cellular response to DNA damage. Has a role in meiosis.
Protein Sequence
(Fasta)
MQFNGSNGID ESSVIDLTRS PSPPVETSIS STNIIDLDAI PDDSFPSSPV LSPRRRRMNR 60
RRNERSRNFP SNHLSYLEDM IYLGPQVSTR RSSSRRDLMG MIARTFPEFS SVNSLSPSLF 120
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Protein Fasta Sequence



>IUUC-Spo-108080|E3,RING|Schizosaccharomyces pombe
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Nucleotide Sequence
(Fasta)
AAAATATATA CAAATAAATC GACTTAATTT TTTGCCCGTT GTCAATTACT TGACAGGAAA 60
CAATTGTGTA TCTTTTTTCA CACATCAATG CAATTTAATG GAAGCAATGG AATAGATGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Spo-108080|E3,RING|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0469--Meiosis
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR009078--Ferritin-like_SF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF14634--zf-RING_5

Gene Ontology

GO:0005634--C:nucleus
GO:0035861--C:site of double-strand break
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0051321--P:meiotic cell cycle
GO:0033234--P:negative regulation of protein sumoylation
GO:0016567--P:protein ubiquitination

KEGG spo:SPAC19A8.10
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aly-006529 Arabidopsis lyrata 33.90 9.00e-03 32.30
IUUC-Acl-008206 Aspergillus clavatus 44.66 4.00e-19 86.70
IUUC-Afu-008960 Aspergillus fumigatus 42.99 2.00e-19 87.80
IUUC-Ani-009203 Aspergillus nidulans 38.98 1.00e-09 54.70
IUUC-Ang-009683 Aspergillus niger 38.89 2.00e-06 44.30
IUUC-Ate-010279 Aspergillus terreus 42.31 3.00e-09 53.90
IUUC-Bgr-012037 Blumeria graminis 26.17 6.00e-03 32.70
IUUC-Bci-013746 Botrytis cinerea 27.35 1.00e-06 45.80
IUUC-Bdi-014006 Brachypodium distachyon 29.52 3.00e-02 32.30
IUUC-Cgl-026565 Colletotrichum gloeosporioides 29.41 1.00e-05 42.70
IUUC-Dse-031380 Dothistroma septosporum 32.26 5.00e-09 52.80
IUUC-Fox-037849 Fusarium oxysporum 35.00 4.00e-06 43.50
IUUC-Fso-038340 Fusarium solani 31.37 4.00e-06 43.50
IUUC-Ggr-039775 Gaeumannomyces graminis 27.13 2.00e-05 41.60
IUUC-Kpa-049252 Komagataella pastoris 36.17 8.00e-03 33.10
IUUC-Mor-057286 Magnaporthe oryzae 23.48 3.00e-04 37.70
IUUC-Mpo-057308 Magnaporthe poae 24.00 4.00e-05 40.80
IUUC-Mvi-060567 Microbotryum violaceum 30.95 1.10e-02 33.10
IUUC-Nfi-068573 Neosartorya fischeri 47.62 1.00e-11 61.20
IUUC-Ncr-068752 Neurospora crassa 35.06 1.00e-07 49.70
IUUC-Ola-087063 Oryzias latipes 48.15 2.90e-02 32.00
IUUC-Olu-087626 Ostreococcus lucimarinus 37.50 9.20e-02 29.30
IUUC-Pno-095022 Phaeosphaeria nodorum 34.65 1.00e-15 75.50
IUUC-Ptt-103949 Puccinia triticina 23.73 2.10e-01 28.50
IUUC-Pte-104074 Pyrenophora teres 34.44 2.00e-11 62.00
IUUC-Pyt-104527 Pyrenophora triticirepentis 34.44 2.00e-11 62.00
IUUC-Sja-107707 Schizosaccharomyces japonicus 42.02 1.00e-33 134.00
IUUC-Ssl-108638 Sclerotinia sclerotiorum 27.73 3.00e-08 50.80
IUUC-Smo-109559 Selaginella moellendorffii 29.85 2.70e-02 33.50
IUUC-Tni-120685 Tetraodon nigroviridis 35.00 3.00e-03 35.00
IUUC-Tre-122231 Trichoderma reesei 34.25 4.00e-04 37.40
IUUC-Tvi-122358 Trichoderma virens 36.49 8.00e-05 39.30
IUUC-Tme-127114 Tuber melanosporum 35.71 3.00e-12 64.30
IUUC-Uma-129623 Ustilago maydis 34.15 1.60e-02 32.00
IUUC-Vda-129864 Verticillium dahliae 27.35 3.00e-03 35.00
IUUC-Yli-134573 Yarrowia lipolytica 24.77 8.00e-06 42.40
Created Date 25-Jun-2017

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