iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009146

Ensembl Protein ID

CADANIAP00007695

UniProt Accession

Q5AXT6; C8V2X0; PPIL2_EMENI

Genbank Protein ID

EAA58293.1; CBF71677.1

Protein Name

Peptidyl-prolyl cis-trans isomerase-like 2; Cyclophilin-60; Cyclophilin-like protein Cyp-60; RING-type E3 ubiquitin transferase isomerase-like 2; Rotamase

Genbank Nucleotide ID

AACD01000113; BN001301

Gene Name

ANIA_06894; cyp8; AN6894

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00007695	CADANIAT00007695	CADANIAP00007695

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.90e-12	46.2	48	109

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 7    lCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
            C++sl+++++Pv+++sG  +d +sI  w+++ g+ +Pv+++pl+ +dl+  +  ++   +++
   Q: 48   FCSLSLQPFEHPVCTQSGTIFDLTSILPWIKKHGT-NPVDGTPLKGSDLIKLTIAKNDAGEYI 109
           6******************************9998.**************9999988666665 PP

Organism

Aspergillus nidulans

Functional Description
(View)

May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.

Protein Sequence
(Fasta)

MGKGTDKLYI THSEWASEDA YSASAGAGVG KARRGVGEAS FKRLPFRFCS LSLQPFEHPV 60
CTQSGTIFDL TSILPWIKKH GTNPVDGTPL KGSDLIKLTI AKNDAGEYID PVTYKVLTDN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGAAAATG GGCAAAGGTC AGTACTCTTA TCTGTGGGCG ATTACTGGTC TAACGCGATA 60
TCCGTACAGG CACGGACAAG CTTTATGTAT GATGAGGAAA TTTGCCTTAC CCAGTTCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0413--Isomerase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0697--Rotamase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR029000--Cyclophilin-like_dom
IPR024936--Cyclophilin-type_PPIase
IPR020892--Cyclophilin-type_PPIase_CS
IPR002130--Cyclophilin-type_PPIase_dom
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00170--CSA_PPIASE_1
PS50072--CSA_PPIASE_2
PS51698--U_BOX

Pfam

PF00160--Pro_isomerase

PRINTS

PR00153--CSAPPISMRASE

SMART

SM00504--Ubox

Gene Ontology

GO:0005634--C:nucleus
GO:0003755--F:peptidyl-prolyl cis-trans isomerase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006457--P:protein folding

KEGG

ani:AN6894.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000982	Aegilops tauschii	38.82	9.00e-84	302.00
IUUC-Aml-002351	Ailuropoda melanoleuca	40.29	8.00e-110	389.00
IUUC-Atr-002724	Amborella trichopoda	40.68	1.00e-95	342.00
IUUC-Apl-003515	Anas platyrhynchos	42.70	3.00e-101	360.00
IUUC-Aca-004802	Anolis carolinensis	41.88	5.00e-111	392.00
IUUC-Aly-005928	Arabidopsis lyrata	40.76	3.00e-95	340.00
IUUC-Ath-007574	Arabidopsis thaliana	39.81	6.00e-89	319.00
IUUC-Acl-008183	Aspergillus clavatus	79.93	0.00e+00	823.00
IUUC-Afl-008382	Aspergillus flavus	77.03	0.00e+00	806.00
IUUC-Afu-008952	Aspergillus fumigatus	79.45	0.00e+00	830.00
IUUC-Ang-009743	Aspergillus niger	82.08	0.00e+00	816.00
IUUC-Aor-010027	Aspergillus oryzae	76.29	0.00e+00	797.00
IUUC-Ate-010569	Aspergillus terreus	81.01	0.00e+00	883.00
IUUC-Ame-010783	Astyanax mexicanus	42.96	3.00e-115	407.00
IUUC-Bgr-012172	Blumeria graminis	47.20	4.00e-117	413.00
IUUC-Bta-012459	Bos taurus	39.97	1.00e-104	372.00
IUUC-Bci-013693	Botrytis cinerea	55.09	7.00e-158	548.00
IUUC-Bdi-014623	Brachypodium distachyon	40.96	2.00e-102	364.00
IUUC-Bol-015781	Brassica oleracea	41.33	7.00e-99	352.00
IUUC-Bra-016624	Brassica rapa	41.71	2.00e-98	351.00
IUUC-Cel-018328	Caenorhabditis elegans	39.08	5.00e-93	333.00
IUUC-Cja-019427	Callithrix jacchus	45.72	2.00e-107	381.00
IUUC-Cfa-020829	Canis familiaris	42.74	1.00e-113	401.00
IUUC-Cpo-022189	Cavia porcellus	42.83	3.00e-112	397.00
IUUC-Cre-022723	Chlamydomonas reinhardtii	38.49	6.00e-89	320.00
IUUC-Csa-024212	Chlorocebus sabaeus	43.63	4.00e-112	396.00
IUUC-Cin-025720	Ciona intestinalis	42.98	9.00e-109	385.00
IUUC-Csv-026137	Ciona savignyi	38.32	3.00e-100	357.00
IUUC-Cgl-026532	Colletotrichum gloeosporioides	54.04	7.00e-156	541.00
IUUC-Cne-026830	Cryptococcus neoformans	41.69	4.00e-116	410.00
IUUC-Dre-028561	Danio rerio	40.65	7.00e-111	392.00
IUUC-Dno-029029	Dasypus novemcinctus	38.33	9.00e-96	342.00
IUUC-Dor-030683	Dipodomys ordii	45.70	2.00e-35	141.00
IUUC-Dse-031506	Dothistroma septosporum	60.14	4.00e-174	602.00
IUUC-Dme-032058	Drosophila melanogaster	39.55	1.00e-99	355.00
IUUC-Ete-033157	Echinops telfairi	34.35	1.00e-72	265.00
IUUC-Eeu-034470	Erinaceus europaeus	44.32	6.00e-69	253.00
IUUC-Fca-036571	Felis catus	42.66	6.00e-112	395.00
IUUC-Fal-037613	Ficedula albicollis	40.11	1.00e-107	382.00
IUUC-Fox-037795	Fusarium oxysporum	52.76	5.00e-165	572.00
IUUC-Fso-038213	Fusarium solani	49.33	2.00e-146	510.00
IUUC-Gmo-039609	Gadus morhua	41.59	7.00e-106	375.00
IUUC-Ggr-039825	Gaeumannomyces graminis	55.91	5.00e-152	529.00
IUUC-Gga-041191	Gallus gallus	41.16	7.00e-109	385.00
IUUC-Gac-041524	Gasterosteus aculeatus	41.64	2.00e-109	387.00
IUUC-Gma-042936	Glycine max	41.27	2.00e-97	347.00
IUUC-Ggo-045352	Gorilla gorilla	42.49	4.00e-111	393.00
IUUC-Hsa-045709	Homo sapiens	42.49	5.00e-111	392.00
IUUC-Hvu-047058	Hordeum vulgare	41.06	6.00e-98	349.00
IUUC-Itr-048483	Ictidomys tridecemlineatus	45.72	7.00e-107	379.00
IUUC-Lch-049681	Latimeria chalumnae	42.16	1.00e-99	355.00
IUUC-Lpe-050799	Leersia perrieri	46.70	1.00e-53	202.00
IUUC-Loc-052566	Lepisosteus oculatus	38.85	5.00e-98	349.00
IUUC-Lma-053028	Leptosphaeria maculans	59.08	5.00e-165	572.00
IUUC-Laf-054547	Loxodonta africana	42.20	2.00e-110	391.00
IUUC-Mcc-054753	Macaca mulatta	42.81	7.00e-109	385.00
IUUC-Meu-056855	Macropus eugenii	31.94	2.00e-35	140.00
IUUC-Mor-056941	Magnaporthe oryzae	53.75	8.00e-147	511.00
IUUC-Mpo-057306	Magnaporthe poae	52.75	3.00e-158	550.00
IUUC-Mtr-058349	Medicago truncatula	41.29	9.00e-95	339.00
IUUC-Mla-058842	Melampsora laricipopulina	41.90	2.00e-110	390.00
IUUC-Mga-060099	Meleagris gallopavo	39.89	1.00e-97	348.00
IUUC-Mvi-060413	Microbotryum violaceum	40.54	2.00e-105	374.00
IUUC-Mmr-061530	Microcebus murinus	42.54	3.00e-113	400.00
IUUC-Mdo-062668	Monodelphis domestica	44.89	4.00e-106	376.00
IUUC-Mmu-063871	Mus musculus	41.57	1.00e-111	394.00
IUUC-Mac-064559	Musa acuminata	45.24	3.00e-50	191.00
IUUC-Mpu-065919	Mustela putorius furo	42.44	1.00e-109	388.00
IUUC-Mlu-067846	Myotis lucifugus	38.12	1.00e-99	355.00
IUUC-Nfi-068507	Neosartorya fischeri	78.24	0.00e+00	776.00
IUUC-Ncr-068805	Neurospora crassa	50.25	2.00e-125	441.00
IUUC-Nle-070125	Nomascus leucogenys	40.20	1.00e-99	355.00
IUUC-Opr-070486	Ochotona princeps	42.35	2.00e-84	304.00
IUUC-Ont-071597	Oreochromis niloticus	43.13	2.00e-117	414.00
IUUC-Ocu-074411	Oryctolagus cuniculus	46.35	4.00e-108	383.00
IUUC-Oba-075040	Oryza barthii	47.64	9.00e-55	206.00
IUUC-Obr-076727	Oryza brachyantha	46.70	3.00e-53	201.00
IUUC-Ogl-077605	Oryza glaberrima	47.64	9.00e-55	206.00
IUUC-Ogu-078177	Oryza glumaepatula	47.64	9.00e-55	206.00
IUUC-Oin-079549	Oryza indica	47.64	1.00e-54	206.00
IUUC-Olo-081090	Oryza longistaminata	47.64	9.00e-55	206.00
IUUC-Ome-081979	Oryza meridionalis	47.64	9.00e-55	206.00
IUUC-Oni-082819	Oryza nivara	47.64	1.00e-54	205.00
IUUC-Opu-083212	Oryza punctata	47.64	7.00e-55	206.00
IUUC-Oru-084412	Oryza rufipogon	47.64	9.00e-55	206.00
IUUC-Osa-085431	Oryza sativa	48.20	3.00e-33	132.00
IUUC-Ola-086602	Oryzias latipes	43.88	2.00e-105	374.00
IUUC-Olu-087682	Ostreococcus lucimarinus	39.23	1.00e-81	295.00
IUUC-Oga-088999	Otolemur garnettii	39.84	6.00e-103	366.00
IUUC-Oar-089338	Ovis aries	38.16	5.00e-82	296.00
IUUC-Ptr-091185	Pan troglodytes	42.49	4.00e-111	393.00
IUUC-Pan-092321	Papio anubis	42.78	4.00e-114	403.00
IUUC-Psi-094018	Pelodiscus sinensis	43.95	3.00e-57	213.00
IUUC-Pma-094111	Petromyzon marinus	41.42	1.00e-77	281.00
IUUC-Pno-094782	Phaeosphaeria nodorum	57.95	3.00e-172	596.00
IUUC-Ppa-095335	Physcomitrella patens	43.18	1.00e-50	192.00
IUUC-Pfo-097393	Poecilia formosa	42.78	2.00e-116	411.00
IUUC-Pab-098263	Pongo abelii	39.42	8.00e-96	342.00
IUUC-Pop-099316	Populus trichocarpa	41.81	2.00e-88	318.00
IUUC-Pca-100387	Procavia capensis	49.64	1.00e-38	152.00
IUUC-Ppe-101275	Prunus persica	40.19	3.00e-96	344.00
IUUC-Pva-102150	Pteropus vampyrus	45.64	2.00e-94	337.00
IUUC-Pgr-103378	Puccinia graminis	44.03	4.00e-118	416.00
IUUC-Ptt-103908	Puccinia triticina	42.35	4.00e-104	370.00
IUUC-Pte-104248	Pyrenophora teres	58.49	1.00e-173	601.00
IUUC-Pyt-104645	Pyrenophora triticirepentis	59.32	1.00e-174	604.00
IUUC-Rno-105162	Rattus norvegicus	42.66	7.00e-115	405.00
IUUC-Sha-107123	Sarcophilus harrisii	42.91	7.00e-48	183.00
IUUC-Sja-107828	Schizosaccharomyces japonicus	45.98	2.00e-122	430.00
IUUC-Spo-108368	Schizosaccharomyces pombe	45.11	3.00e-130	456.00
IUUC-Smo-109102	Selaginella moellendorffii	40.00	3.00e-99	353.00
IUUC-Sit-110821	Setaria italica	46.70	2.00e-53	201.00
IUUC-Sly-111803	Solanum lycopersicum	37.25	3.00e-102	364.00
IUUC-Stu-112730	Solanum tuberosum	39.81	1.00e-100	358.00
IUUC-Sar-113618	Sorex araneus	43.07	2.00e-108	384.00
IUUC-Sbi-114487	Sorghum bicolor	42.56	2.00e-99	354.00
IUUC-Sre-115009	Sporisorium reilianum	40.17	2.00e-102	364.00
IUUC-Ssc-115984	Sus scrofa	41.58	1.00e-109	388.00
IUUC-Tgu-117410	Taeniopygia guttata	40.55	1.00e-108	384.00
IUUC-Tru-118537	Takifugu rubripes	42.17	3.00e-113	400.00
IUUC-Tsy-119318	Tarsius syrichta	33.85	1.00e-41	162.00
IUUC-Tni-120514	Tetraodon nigroviridis	40.08	7.00e-76	275.00
IUUC-Tca-121620	Theobroma cacao	41.32	1.00e-95	342.00
IUUC-Tre-121904	Trichoderma reesei	47.77	2.00e-125	440.00
IUUC-Tvi-122585	Trichoderma virens	50.75	3.00e-128	450.00
IUUC-Tae-125342	Triticum aestivum	40.87	2.00e-97	348.00
IUUC-Tme-126960	Tuber melanosporum	54.48	5.00e-164	568.00
IUUC-Tbe-127839	Tupaia belangeri	35.12	1.00e-33	135.00
IUUC-Ttr-129173	Tursiops truncatus	33.62	4.00e-74	270.00
IUUC-Uma-129595	Ustilago maydis	38.53	3.00e-93	334.00
IUUC-Vda-130012	Verticillium dahliae	54.83	4.00e-155	539.00
IUUC-Vvi-131156	Vitis vinifera	39.66	3.00e-101	360.00
IUUC-Xtr-132807	Xenopus tropicalis	37.89	4.00e-102	363.00
IUUC-Yli-134361	Yarrowia lipolytica	50.26	1.00e-35	142.00
IUUC-Zma-135759	Zea mays	39.15	9.00e-48	183.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence