iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059229

UUCD1 version

UUC-MeG-00236

Ensembl Protein ID

ENSMGAP00000004658.2

UniProt Accession

G1MZY4; G1MZY4_MELGA

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36

Gene Name

EIF3I; EIF3S2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000004802.2	ENSMGAT00000005379.2	ENSMGAP00000004658.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-19	67.2	50	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvs..GsdDgtikvWDlrtgvll 36
           gHt+ v+c+  ++ d +++++  Gs D+++++WD  tg++l
   Q: 50   GHTGAVWCVdaDW-DtRHVLTxxGSADNSCRLWDCETGKQL 89
           8*******98679.5599*******************9986 PP

Organism

Meleagris gallopavo

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

QKPILLQGHG RSITQIKYNR EGDLLFTVAK DPIVNVWYSV NGERLGTYNG HTGAVWCVDA 60
DWDTRHVLTX XGSADNSCRL WDCETGKQLA LVKTSSAVRT CGFDFGGNII MFSTDKQMGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCACGCAG AAGCCGATCC TGCTGCAGGG CCACGGGCGT TCCATCACGC AGATCAAGTA 60
CAACCGCGAG GGAGACCTGC TGTTCACTGT GGCCAAGGAT CCCGTGAGTA TGGCTGAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071541--C:eukaryotic translation initiation factor 3 complex, eIF3m
GO:0070062--C:extracellular exosome
GO:0003743--F:translation initiation factor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	58.41	3.00e-35	142.00
IUUC-Aml-001321	Ailuropoda melanoleuca	92.66	0.00e+00	636.00
IUUC-Atr-002468	Amborella trichopoda	50.78	2.00e-53	201.00
IUUC-Apl-003841	Anas platyrhynchos	99.08	0.00e+00	674.00
IUUC-Aca-005123	Anolis carolinensis	93.87	0.00e+00	640.00
IUUC-Aly-005473	Arabidopsis lyrata	44.24	1.00e-81	296.00
IUUC-Ath-007094	Arabidopsis thaliana	45.90	2.00e-83	301.00
IUUC-Ago-008000	Ashbya gossypii	44.28	8.00e-80	290.00
IUUC-Acl-008098	Aspergillus clavatus	53.15	5.00e-101	360.00
IUUC-Afl-008494	Aspergillus flavus	52.74	6.00e-101	360.00
IUUC-Afu-009080	Aspergillus fumigatus	53.45	3.00e-101	360.00
IUUC-Ani-009230	Aspergillus nidulans	53.19	3.00e-101	361.00
IUUC-Aor-010114	Aspergillus oryzae	52.74	6.00e-101	360.00
IUUC-Ate-010285	Aspergillus terreus	54.41	2.00e-103	368.00
IUUC-Ame-011534	Astyanax mexicanus	82.01	9.00e-168	582.00
IUUC-Bgr-012121	Blumeria graminis	48.18	1.00e-87	315.00
IUUC-Bta-013143	Bos taurus	92.33	0.00e+00	634.00
IUUC-Bci-013950	Botrytis cinerea	50.91	8.00e-96	342.00
IUUC-Bdi-015019	Brachypodium distachyon	46.48	3.00e-85	308.00
IUUC-Bol-015709	Brassica oleracea	45.92	2.00e-80	292.00
IUUC-Bra-017760	Brassica rapa	45.92	9.00e-81	294.00
IUUC-Cel-018226	Caenorhabditis elegans	42.68	6.00e-79	286.00
IUUC-Cja-019741	Callithrix jacchus	93.25	0.00e+00	639.00
IUUC-Cfa-021204	Canis familiaris	92.66	0.00e+00	637.00
IUUC-Cpo-021661	Cavia porcellus	92.66	0.00e+00	637.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	43.52	9.00e-80	289.00
IUUC-Csa-024038	Chlorocebus sabaeus	93.25	0.00e+00	639.00
IUUC-Cin-025597	Ciona intestinalis	59.51	2.00e-116	411.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	50.46	2.00e-92	331.00
IUUC-Cne-026838	Cryptococcus neoformans	48.48	3.00e-92	331.00
IUUC-Cme-027304	Cyanidioschyzon merolae	44.58	7.00e-79	286.00
IUUC-Dre-028567	Danio rerio	84.66	2.00e-172	597.00
IUUC-Dno-029171	Dasypus novemcinctus	92.64	0.00e+00	635.00
IUUC-Dor-030257	Dipodomys ordii	82.49	2.00e-80	291.00
IUUC-Dse-031191	Dothistroma septosporum	49.85	3.00e-92	331.00
IUUC-Dme-031879	Drosophila melanogaster	59.33	1.00e-117	415.00
IUUC-Ete-032336	Echinops telfairi	90.65	1.00e-116	410.00
IUUC-Eca-033259	Equus caballus	92.97	0.00e+00	639.00
IUUC-Eeu-035153	Erinaceus europaeus	70.47	5.00e-55	207.00
IUUC-Fca-036489	Felis catus	92.97	0.00e+00	639.00
IUUC-Fal-037485	Ficedula albicollis	98.47	0.00e+00	672.00
IUUC-Fox-037860	Fusarium oxysporum	49.09	7.00e-92	330.00
IUUC-Fso-038188	Fusarium solani	50.00	4.00e-91	327.00
IUUC-Gmo-039311	Gadus morhua	84.97	5.00e-173	599.00
IUUC-Ggr-040045	Gaeumannomyces graminis	50.76	3.00e-96	344.00
IUUC-Gga-040645	Gallus gallus	96.71	0.00e+00	665.00
IUUC-Gac-042086	Gasterosteus aculeatus	83.44	2.00e-168	583.00
IUUC-Gma-043246	Glycine max	45.57	5.00e-84	303.00
IUUC-Ggo-045578	Gorilla gorilla	93.25	0.00e+00	639.00
IUUC-Hsa-046734	Homo sapiens	93.25	0.00e+00	639.00
IUUC-Hvu-047553	Hordeum vulgare	45.87	2.00e-84	305.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	92.97	0.00e+00	639.00
IUUC-Kpa-049325	Komagataella pastoris	44.21	6.00e-83	300.00
IUUC-Lch-049620	Latimeria chalumnae	86.29	9.00e-160	555.00
IUUC-Lpe-051338	Leersia perrieri	45.19	1.00e-77	282.00
IUUC-Loc-052094	Lepisosteus oculatus	80.37	8.00e-160	555.00
IUUC-Lma-053047	Leptosphaeria maculans	48.79	1.00e-92	332.00
IUUC-Laf-053801	Loxodonta africana	92.81	1.00e-180	624.00
IUUC-Mcc-055498	Macaca mulatta	83.13	4.00e-155	540.00
IUUC-Meu-056729	Macropus eugenii	86.24	3.00e-166	576.00
IUUC-Mor-057025	Magnaporthe oryzae	51.22	5.00e-94	337.00
IUUC-Mpo-057511	Magnaporthe poae	51.83	2.00e-96	344.00
IUUC-Mtr-058051	Medicago truncatula	46.65	5.00e-84	303.00
IUUC-Mla-059061	Melampsora laricipopulina	47.20	3.00e-83	301.00
IUUC-Mvi-060399	Microbotryum violaceum	46.85	2.00e-80	291.00
IUUC-Mmr-060764	Microcebus murinus	92.64	0.00e+00	635.00
IUUC-Mdo-062088	Monodelphis domestica	92.38	0.00e+00	637.00
IUUC-Mmu-064304	Mus musculus	92.64	0.00e+00	636.00
IUUC-Mac-065520	Musa acuminata	47.53	3.00e-86	310.00
IUUC-Mpu-066340	Mustela putorius furo	92.97	0.00e+00	639.00
IUUC-Mlu-067111	Myotis lucifugus	92.97	0.00e+00	639.00
IUUC-Nfi-068478	Neosartorya fischeri	52.85	5.00e-101	360.00
IUUC-Ncr-068820	Neurospora crassa	51.98	6.00e-95	340.00
IUUC-Nle-069903	Nomascus leucogenys	93.27	0.00e+00	642.00
IUUC-Opr-070221	Ochotona princeps	90.49	3.00e-178	616.00
IUUC-Ont-071765	Oreochromis niloticus	85.58	2.00e-173	600.00
IUUC-Oan-073660	Ornithorhynchus anatinus	92.91	2.00e-167	581.00
IUUC-Ocu-074039	Oryctolagus cuniculus	93.27	0.00e+00	640.00
IUUC-Oba-075395	Oryza barthii	38.84	1.00e-66	245.00
IUUC-Obr-076334	Oryza brachyantha	42.51	4.00e-76	277.00
IUUC-Ogl-077060	Oryza glaberrima	45.90	9.00e-82	296.00
IUUC-Ogu-078207	Oryza glumaepatula	46.01	1.00e-84	305.00
IUUC-Oin-079878	Oryza indica	45.57	5.00e-84	303.00
IUUC-Olo-080677	Oryza longistaminata	38.58	3.00e-74	271.00
IUUC-Ome-081228	Oryza meridionalis	32.64	3.00e-32	131.00
IUUC-Oni-082411	Oryza nivara	39.58	8.00e-67	246.00
IUUC-Opu-083136	Oryza punctata	44.65	1.00e-82	299.00
IUUC-Oru-084916	Oryza rufipogon	44.64	5.00e-82	297.00
IUUC-Osa-085454	Oryza sativa	45.57	5.00e-84	303.00
IUUC-Ola-087053	Oryzias latipes	84.66	3.00e-172	596.00
IUUC-Olu-087602	Ostreococcus lucimarinus	47.68	1.00e-85	309.00
IUUC-Oga-088154	Otolemur garnettii	92.97	0.00e+00	637.00
IUUC-Oar-089915	Ovis aries	92.35	0.00e+00	635.00
IUUC-Ptr-091124	Pan troglodytes	74.84	1.00e-137	481.00
IUUC-Pan-092035	Papio anubis	93.25	0.00e+00	639.00
IUUC-Psi-094096	Pelodiscus sinensis	91.24	5.00e-119	419.00
IUUC-Pno-094988	Phaeosphaeria nodorum	45.35	2.00e-80	291.00
IUUC-Ppa-095536	Physcomitrella patens	49.08	1.00e-89	322.00
IUUC-Pfo-096101	Poecilia formosa	84.05	3.00e-171	593.00
IUUC-Pab-097726	Pongo abelii	93.25	0.00e+00	639.00
IUUC-Pop-099617	Populus trichocarpa	46.79	1.00e-85	309.00
IUUC-Pca-101014	Procavia capensis	92.94	0.00e+00	637.00
IUUC-Ppe-101320	Prunus persica	46.48	3.00e-83	301.00
IUUC-Pva-102789	Pteropus vampyrus	80.98	3.00e-154	536.00
IUUC-Pgr-103479	Puccinia graminis	46.89	2.00e-82	298.00
IUUC-Ptt-103981	Puccinia triticina	47.52	2.00e-84	305.00
IUUC-Pte-104278	Pyrenophora teres	49.09	1.00e-90	325.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	49.09	1.00e-90	325.00
IUUC-Rno-105867	Rattus norvegicus	71.87	6.00e-130	456.00
IUUC-Sce-106251	Saccharomyces cerevisiae	45.21	2.00e-82	298.00
IUUC-Sha-107039	Sarcophilus harrisii	92.07	0.00e+00	637.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	51.83	6.00e-96	343.00
IUUC-Spo-108314	Schizosaccharomyces pombe	48.93	2.00e-90	325.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	50.15	6.00e-95	340.00
IUUC-Smo-108728	Selaginella moellendorffii	46.93	5.00e-83	300.00
IUUC-Sit-110801	Setaria italica	45.26	3.00e-82	297.00
IUUC-Sly-111326	Solanum lycopersicum	46.65	2.00e-84	305.00
IUUC-Stu-112458	Solanum tuberosum	47.26	3.00e-84	304.00
IUUC-Sbi-114063	Sorghum bicolor	44.65	3.00e-81	294.00
IUUC-Sre-115096	Sporisorium reilianum	47.29	1.00e-82	299.00
IUUC-Ssc-116080	Sus scrofa	92.64	0.00e+00	635.00
IUUC-Tgu-116988	Taeniopygia guttata	98.16	0.00e+00	668.00
IUUC-Tru-118766	Takifugu rubripes	84.05	1.00e-171	595.00
IUUC-Tni-120197	Tetraodon nigroviridis	83.44	3.00e-171	593.00
IUUC-Tca-121316	Theobroma cacao	46.18	5.00e-84	303.00
IUUC-Tre-122097	Trichoderma reesei	50.46	4.00e-93	333.00
IUUC-Tvi-122442	Trichoderma virens	50.46	2.00e-93	335.00
IUUC-Tae-125800	Triticum aestivum	45.87	2.00e-84	305.00
IUUC-Tur-126334	Triticum urartu	40.06	5.00e-67	247.00
IUUC-Tme-127038	Tuber melanosporum	52.58	2.00e-99	355.00
IUUC-Ttr-128659	Tursiops truncatus	87.73	9.00e-160	555.00
IUUC-Uma-129464	Ustilago maydis	47.59	3.00e-82	298.00
IUUC-Vda-129841	Verticillium dahliae	52.44	5.00e-95	340.00
IUUC-Vvi-131076	Vitis vinifera	46.65	3.00e-84	304.00
IUUC-Xtr-132395	Xenopus tropicalis	88.96	4.00e-179	619.00
IUUC-Xma-133383	Xiphophorus maculatus	83.74	1.00e-170	591.00
IUUC-Yli-134586	Yarrowia lipolytica	48.94	4.00e-80	290.00
IUUC-Zma-135904	Zea mays	45.57	3.00e-82	297.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence