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Tag Content
iUUCD ID IUUC-Dre-028073
Ensembl Protein ID ENSDARP00000136909.1
UniProt Accession A0A0R4ISU0; A0A0R4ISU0_DANRE
Genbank Protein ID ENSDARP00000136909
Protein Name DNA repair protein REV1
Genbank Nucleotide ID CR392332
Gene Name rev1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000018296.10 ENSDART00000134915.2 ENSDARP00000115859.1
ENSDARG00000018296.10 ENSDART00000169069.1 ENSDARP00000136909.1
ENSDARG00000018296.10 ENSDART00000059652.6 ENSDARP00000059651.5
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 1.30e-17 63.7 977 1003
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM
   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrq 27
           +PsqvDp+V+++LP +i+++v+  +r 
   Q: 977  SPSQVDPSVLKALPIDIRRQVEETWRY 1003
           7*********************99985 PP
   
Organism Danio rerio
Functional Description
(View)

Functional Description


     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
 Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MSRDGWRKKA SENDGWGGQG GYMAAKVSKL EEQFQKDAPR EQKKDGKSSC IFSGVAIYVN 60
GYTDPSAAEL RRLMMLHGGQ FHLYYSRSKT THIIATNLPN FKIQELKGEK VVRPEWIIDS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028073|UBD,UBM|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACAGACAGGG CTGGCGCTGT CACTGTGTGA CCCCGGCTGA GAGAAGGAGG AGGAGGAGGG 60
TCTTACGCCG AAAACAAGCA GAAAATCTGG CGGAGGCGAC AGTGAGCAAG CGGCTAGCAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028073|UBD,UBM|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC
PROSITE

PS50172--BRCT
PS50173--UMUC
Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C
SMART

SM00292--BRCT
Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0016779--F:nucleotidyltransferase activity
GO:0042276--P:error-prone translesion synthesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 40.96 9.00e-32 132.00
IUUC-Aml-001185 Ailuropoda melanoleuca 50.79 0.00e+00 1065.00
IUUC-Atr-002915 Amborella trichopoda 43.55 2.00e-70 261.00
IUUC-Apl-004054 Anas platyrhynchos 49.77 0.00e+00 1022.00
IUUC-Aca-004304 Anolis carolinensis 49.96 0.00e+00 1088.00
IUUC-Aly-005696 Arabidopsis lyrata 45.51 1.00e-74 275.00
IUUC-Ath-006893 Arabidopsis thaliana 45.76 1.00e-75 278.00
IUUC-Ago-007722 Ashbya gossypii 31.59 5.00e-38 153.00
IUUC-Acl-008347 Aspergillus clavatus 41.35 2.00e-70 261.00
IUUC-Afl-008444 Aspergillus flavus 34.85 3.00e-74 273.00
IUUC-Afu-008837 Aspergillus fumigatus 29.46 2.00e-73 271.00
IUUC-Ani-009188 Aspergillus nidulans 29.95 4.00e-75 276.00
IUUC-Ang-009866 Aspergillus niger 34.12 1.00e-69 258.00
IUUC-Aor-010107 Aspergillus oryzae 34.85 4.00e-74 273.00
IUUC-Ate-010359 Aspergillus terreus 42.01 2.00e-73 271.00
IUUC-Ame-010664 Astyanax mexicanus 65.07 0.00e+00 1546.00
IUUC-Bgr-012244 Blumeria graminis 39.04 1.00e-63 238.00
IUUC-Bta-013405 Bos taurus 53.23 0.00e+00 796.00
IUUC-Bci-013849 Botrytis cinerea 32.65 3.00e-74 273.00
IUUC-Bdi-014066 Brachypodium distachyon 43.99 8.00e-76 279.00
IUUC-Bol-015544 Brassica oleracea 45.45 2.00e-75 277.00
IUUC-Bra-017792 Brassica rapa 34.73 1.00e-78 288.00
IUUC-Cel-018148 Caenorhabditis elegans 34.82 2.00e-76 281.00
IUUC-Cja-019742 Callithrix jacchus 40.94 0.00e+00 652.00
IUUC-Cfa-020112 Canis familiaris 50.04 0.00e+00 1052.00
IUUC-Cpo-022152 Cavia porcellus 49.28 0.00e+00 1056.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 32.33 8.00e-46 178.00
IUUC-Csa-023504 Chlorocebus sabaeus 50.79 0.00e+00 1049.00
IUUC-Cho-024780 Choloepus hoffmanni 42.27 3.00e-72 267.00
IUUC-Cin-025276 Ciona intestinalis 53.00 8.00e-99 354.00
IUUC-Csv-026283 Ciona savignyi 41.90 3.00e-100 359.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 29.52 6.00e-76 279.00
IUUC-Cne-027079 Cryptococcus neoformans 40.69 9.00e-73 269.00
IUUC-Cme-027346 Cyanidioschyzon merolae 30.47 4.00e-43 170.00
IUUC-Dno-030038 Dasypus novemcinctus 50.80 0.00e+00 1055.00
IUUC-Dor-031100 Dipodomys ordii 49.15 0.00e+00 747.00
IUUC-Dse-031310 Dothistroma septosporum 30.30 1.00e-73 271.00
IUUC-Dme-031991 Drosophila melanogaster 41.85 1.00e-102 368.00
IUUC-Ete-033082 Echinops telfairi 56.65 5.00e-153 535.00
IUUC-Eca-033471 Equus caballus 49.93 0.00e+00 1065.00
IUUC-Eeu-034993 Erinaceus europaeus 51.14 0.00e+00 764.00
IUUC-Fca-035367 Felis catus 49.64 0.00e+00 991.00
IUUC-Fal-036973 Ficedula albicollis 49.55 0.00e+00 1011.00
IUUC-Fox-037677 Fusarium oxysporum 34.53 7.00e-76 279.00
IUUC-Fso-038252 Fusarium solani 29.74 3.00e-82 300.00
IUUC-Gmo-039669 Gadus morhua 66.73 0.00e+00 672.00
IUUC-Ggr-039988 Gaeumannomyces graminis 31.96 4.00e-68 253.00
IUUC-Gga-040423 Gallus gallus 50.23 0.00e+00 1035.00
IUUC-Gac-042134 Gasterosteus aculeatus 57.06 0.00e+00 682.00
IUUC-Gma-042929 Glycine max 36.35 8.00e-85 309.00
IUUC-Ggo-044528 Gorilla gorilla 50.64 0.00e+00 1050.00
IUUC-Hsa-046259 Homo sapiens 49.93 0.00e+00 1041.00
IUUC-Hvu-047139 Hordeum vulgare 45.36 3.00e-43 169.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 50.34 0.00e+00 1074.00
IUUC-Kpa-049169 Komagataella pastoris 34.41 1.00e-55 211.00
IUUC-Lch-050471 Latimeria chalumnae 54.58 0.00e+00 882.00
IUUC-Lpe-050800 Leersia perrieri 42.27 4.00e-73 270.00
IUUC-Loc-052320 Lepisosteus oculatus 47.27 0.00e+00 682.00
IUUC-Lma-053149 Leptosphaeria maculans 39.64 7.00e-73 269.00
IUUC-Laf-053810 Loxodonta africana 49.70 0.00e+00 1018.00
IUUC-Mcc-055574 Macaca mulatta 50.64 0.00e+00 1041.00
IUUC-Meu-055945 Macropus eugenii 36.27 2.00e-137 484.00
IUUC-Mor-057195 Magnaporthe oryzae 32.15 3.00e-72 267.00
IUUC-Mpo-057488 Magnaporthe poae 41.49 4.00e-68 253.00
IUUC-Mtr-057955 Medicago truncatula 43.83 2.00e-74 274.00
IUUC-Mla-059027 Melampsora laricipopulina 36.17 1.00e-76 281.00
IUUC-Mga-060156 Meleagris gallopavo 50.61 0.00e+00 1036.00
IUUC-Mvi-060398 Microbotryum violaceum 34.39 6.00e-74 273.00
IUUC-Mmr-061113 Microcebus murinus 50.37 0.00e+00 1041.00
IUUC-Mdo-063001 Monodelphis domestica 50.04 0.00e+00 1052.00
IUUC-Mmu-063180 Mus musculus 49.44 0.00e+00 1048.00
IUUC-Mac-065551 Musa acuminata 38.91 2.00e-52 200.00
IUUC-Mpu-066525 Mustela putorius furo 50.53 0.00e+00 1060.00
IUUC-Mlu-067877 Myotis lucifugus 50.41 0.00e+00 1055.00
IUUC-Nfi-068418 Neosartorya fischeri 29.51 1.00e-73 272.00
IUUC-Ncr-068648 Neurospora crassa 33.27 1.00e-73 272.00
IUUC-Nle-069959 Nomascus leucogenys 49.81 0.00e+00 1045.00
IUUC-Opr-070522 Ochotona princeps 49.81 0.00e+00 671.00
IUUC-Ont-072293 Oreochromis niloticus 52.65 0.00e+00 979.00
IUUC-Oan-073519 Ornithorhynchus anatinus 49.22 0.00e+00 1054.00
IUUC-Ocu-074492 Oryctolagus cuniculus 49.67 0.00e+00 734.00
IUUC-Oba-075567 Oryza barthii 37.09 1.00e-75 278.00
IUUC-Obr-076332 Oryza brachyantha 44.31 3.00e-77 284.00
IUUC-Ogl-077348 Oryza glaberrima 37.09 2.00e-75 278.00
IUUC-Ogu-078779 Oryza glumaepatula 37.12 3.00e-75 277.00
IUUC-Oin-079738 Oryza indica 33.26 1.00e-63 238.00
IUUC-Olo-080701 Oryza longistaminata 33.06 2.00e-63 238.00
IUUC-Ome-081708 Oryza meridionalis 36.62 5.00e-75 276.00
IUUC-Oni-082251 Oryza nivara 36.88 2.00e-73 271.00
IUUC-Opu-083528 Oryza punctata 35.81 7.00e-71 262.00
IUUC-Oru-084293 Oryza rufipogon 36.44 5.00e-72 266.00
IUUC-Osa-085549 Oryza sativa 37.31 8.00e-76 279.00
IUUC-Ola-086793 Oryzias latipes 59.08 0.00e+00 1006.00
IUUC-Olu-087786 Ostreococcus lucimarinus 28.25 2.00e-51 197.00
IUUC-Oga-089006 Otolemur garnettii 49.93 0.00e+00 1048.00
IUUC-Oar-089597 Ovis aries 49.85 0.00e+00 1030.00
IUUC-Ptr-091520 Pan troglodytes 49.85 0.00e+00 1039.00
IUUC-Pan-092333 Papio anubis 50.15 0.00e+00 1032.00
IUUC-Psi-094004 Pelodiscus sinensis 52.05 0.00e+00 828.00
IUUC-Pma-094128 Petromyzon marinus 52.00 3.00e-91 329.00
IUUC-Pno-094849 Phaeosphaeria nodorum 38.24 2.00e-66 248.00
IUUC-Ppa-095714 Physcomitrella patens 30.87 9.00e-79 288.00
IUUC-Pfo-096569 Poecilia formosa 55.34 0.00e+00 1229.00
IUUC-Pab-097960 Pongo abelii 50.19 0.00e+00 1037.00
IUUC-Pop-098921 Populus trichocarpa 43.11 5.00e-73 270.00
IUUC-Pca-100509 Procavia capensis 48.72 4.00e-138 486.00
IUUC-Ppe-101730 Prunus persica 45.15 1.00e-78 288.00
IUUC-Pva-102142 Pteropus vampyrus 48.85 0.00e+00 1026.00
IUUC-Pgr-103446 Puccinia graminis 30.17 1.00e-60 228.00
IUUC-Ptt-103849 Puccinia triticina 41.29 2.00e-66 248.00
IUUC-Pte-104128 Pyrenophora teres 32.63 3.00e-75 277.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 34.14 3.00e-73 270.00
IUUC-Rno-104871 Rattus norvegicus 50.23 0.00e+00 1057.00
IUUC-Sce-106236 Saccharomyces cerevisiae 31.21 1.00e-36 148.00
IUUC-Sha-106962 Sarcophilus harrisii 48.99 0.00e+00 1019.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 37.00 2.00e-49 191.00
IUUC-Spo-108170 Schizosaccharomyces pombe 39.25 8.00e-50 192.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 40.77 4.00e-73 270.00
IUUC-Smo-109554 Selaginella moellendorffii 36.81 4.00e-77 283.00
IUUC-Sit-110479 Setaria italica 45.22 4.00e-70 260.00
IUUC-Sly-111752 Solanum lycopersicum 34.22 1.00e-67 251.00
IUUC-Sar-113304 Sorex araneus 50.46 0.00e+00 1029.00
IUUC-Sbi-114196 Sorghum bicolor 44.14 2.00e-71 264.00
IUUC-Sre-115151 Sporisorium reilianum 30.06 5.00e-74 273.00
IUUC-Ssc-116104 Sus scrofa 50.79 0.00e+00 1042.00
IUUC-Tgu-117438 Taeniopygia guttata 50.04 0.00e+00 1009.00
IUUC-Tru-118553 Takifugu rubripes 55.25 0.00e+00 1206.00
IUUC-Tsy-119056 Tarsius syrichta 48.63 0.00e+00 962.00
IUUC-Tni-119933 Tetraodon nigroviridis 56.85 0.00e+00 984.00
IUUC-Tca-121376 Theobroma cacao 42.21 4.00e-71 263.00
IUUC-Tre-121972 Trichoderma reesei 41.67 4.00e-65 243.00
IUUC-Tvi-122342 Trichoderma virens 30.25 2.00e-72 267.00
IUUC-Tae-123898 Triticum aestivum 43.99 2.00e-75 277.00
IUUC-Tur-126735 Triticum urartu 40.76 2.00e-37 151.00
IUUC-Tme-126999 Tuber melanosporum 35.31 1.00e-63 239.00
IUUC-Tbe-127280 Tupaia belangeri 57.21 1.00e-64 242.00
IUUC-Ttr-129104 Tursiops truncatus 50.91 0.00e+00 1040.00
IUUC-Uma-129562 Ustilago maydis 31.67 1.00e-71 265.00
IUUC-Vda-129862 Verticillium dahliae 29.50 1.00e-82 301.00
IUUC-Vpa-130819 Vicugna pacos 48.54 8.00e-167 581.00
IUUC-Vvi-131111 Vitis vinifera 43.99 2.00e-74 274.00
IUUC-Xtr-132629 Xenopus tropicalis 47.67 0.00e+00 987.00
IUUC-Xma-134065 Xiphophorus maculatus 55.72 0.00e+00 1018.00
IUUC-Yli-134633 Yarrowia lipolytica 38.48 7.00e-56 213.00
IUUC-Zma-135176 Zea mays 44.57 9.00e-77 282.00
Created Date 25-Jun-2017

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