iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108373

Ensembl Protein ID

SPBC15D4.03.1:pep

UniProt Accession

O74309; SLM9_SCHPO

Genbank Protein ID

CAA20478.1

Protein Name

Histone transcription regulator slm9

Genbank Nucleotide ID

CU329671

Gene Name

slm9; SPBC15D4.03

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC15D4.03	SPBC15D4.03.1	SPBC15D4.03.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-07	29.0	276	316

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.........sdtllvsGsdDgtikvWDlrt 32
           gH+++  c  f         +  +++s+++Dg + +W++ +
   Q: 276  GHQGPLECATFnpylyedpfQKSIIASAAHDGCVSIWNTAC 316
           8999999999988887655422469*************765 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Probably required for replication-independent chromatin assembly (By similarity). Required for transcriptional silencing in the outer repeat (otr) centromeric repeats and the Tf2 long terminal repeat retrotransposons. May play an indirect role in the regulation of cdc2 and/or wee1 at the G2/M stage of mitosis.

Protein Sequence
(Fasta)

MHIFVPKLLE NHQFSSISSS KDFVAVSAET NVYILSKDFF YPKSSEKRII QSLNGHKTTH 60
LSFDSPISCI RFTYDGSCLA VATEAGTFLY HSEKWDKAFQ VLSGPAYEVC WSQQGHILAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTAAGTCTC CCAGACGAGA CTGTATTCAA CGCACTTCAA CGCCATAGCC GAACCCGATA 60
GTGAACGTTA TTCATGAATT GGGAGAATGA AAAATAAAAG TTAGTAAACA AAAGTTCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0005829--C:cytosol
GO:0000417--C:HIR complex
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0030702--P:chromatin silencing at centromere
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0070868--P:heterochromatin organization involved in chromatin silencing
GO:0000070--P:mitotic sister chromatid segregation
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

KEGG

spo:SPBC15D4.03

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence