iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107142

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01133703

Gene Name

LOC100920292

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000015755.1	ENSSHAT00000018714.1	ENSSHAP00000018560.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.50e-225	749.2	452	932

Active Site

Position(s)	Description	Evidence
633	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Q++++G++ qekl+++k++lvGag++GcEllKn++++G+     g++ v+Dmdt+e+snlnrqFLfr++dv k K+++aa+a++++
   Q: 452  YDGQVAVFGSHLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLgcgdgGEVIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQM 540
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkt 170
           np+++v++h++++ +++e+i+   Ff+ +d+V +aldn++ar++++r+c+++r+pl+esgtlG++G+v+v+i+ lte+ys+s+dpp+k+
   Q: 541  NPQMRVTSHQNRVGPDTERIYdddFFQALDGVTNALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKS 629
           ***************************************************************************************** PP
   S: 171  iPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafak 247
           iP+ctlk++pna+eht++wa            + +n++l ++++++e++ +l+ ++++e +++v+++l+ ++++ +++++++a+ +++ 
   Q: 630  IPICTLKNFPNAIEHTLQWArdefeglfkqsaESVNQYL-TDPKFVERALRLAGSQPLELLEAVQRSLVLQRPRAWADCVAWACLHWHA 717
           *******************************99999999.999********************************************** PP
   S: 248  ttinsikqllksfecdivtkskspfwv..................................................sfcsnaealqvp 286
           ++ n+i+qll++f+++++t+s++pfw+                                                   +++  + ++  
   Q: 718  QYVNNIRQLLHNFPPEQLTSSGAPFWSgpkrcphpltfdiqnplhldyivaaanlfaqtyglvgsrdrtavaaliqtVHVPEFTPKSGV 806
           ****************************************************************9999988888877444444444445 PP
   S: 287  ekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipa 368
           + +++d+e ++as +     l+ l++ l ++ek  g k++ ++fekddd   ++d++ aa+nlrae+++i+p +d+++ k iag+iipa
   Q: 807  KIHISDQELQSASISvddsrLEELKAMLPSLEKLAGFKMYPIDFEKDDDNnfHMDFIVAASNLRAENYDIPP-ADRHKSKLIAGKIIPA 894
           66666666666666666777****************************************************.**************** PP
   S: 369  iattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           iatt+a+  Gl+++E++Kvv+g  + e++kn fl++a+
   Q: 895  IATTTAAMVGLVCLELYKVVQGhrRLEAYKNGFLNLAL 932
           **********************9999********9875 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MMSSSPLSKK RRVSGPEPKP GSNCSPTHPV PSEVPTTPAN GMAKNGNEAD IDEGLYSRQL 60
YVLGHDAMKR LQTSSVLVSG LRGLGVEIAK NIILGGVKAV TLHDQGAAQW ADLSSQFYLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNGGGG 60
GGGGCATCAG CCCTGCCTCC CTCACCCTTT TCACCCCGGG ACCTTGAGTG GGTGGGTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	46.63	0.00e+00	858.00
IUUC-Aml-001311	Ailuropoda melanoleuca	86.44	0.00e+00	1907.00
IUUC-Atr-002684	Amborella trichopoda	45.30	0.00e+00	894.00
IUUC-Aca-004620	Anolis carolinensis	78.64	0.00e+00	1739.00
IUUC-Aly-005515	Arabidopsis lyrata	45.61	0.00e+00	910.00
IUUC-Ath-006891	Arabidopsis thaliana	45.80	0.00e+00	916.00
IUUC-Ago-007873	Ashbya gossypii	53.84	0.00e+00	1046.00
IUUC-Acl-008181	Aspergillus clavatus	53.91	0.00e+00	1059.00
IUUC-Afl-008455	Aspergillus flavus	53.26	0.00e+00	1014.00
IUUC-Afu-009065	Aspergillus fumigatus	53.57	0.00e+00	1073.00
IUUC-Ani-009371	Aspergillus nidulans	53.00	0.00e+00	1043.00
IUUC-Ang-009737	Aspergillus niger	53.26	0.00e+00	1051.00
IUUC-Aor-010007	Aspergillus oryzae	53.26	0.00e+00	1014.00
IUUC-Ate-010466	Aspergillus terreus	53.21	0.00e+00	1080.00
IUUC-Ame-010933	Astyanax mexicanus	77.71	0.00e+00	1659.00
IUUC-Bgr-012281	Blumeria graminis	52.94	0.00e+00	1069.00
IUUC-Bta-012767	Bos taurus	87.52	0.00e+00	1935.00
IUUC-Bci-013721	Botrytis cinerea	54.20	0.00e+00	1027.00
IUUC-Bdi-014335	Brachypodium distachyon	46.24	0.00e+00	893.00
IUUC-Bol-015665	Brassica oleracea	44.89	0.00e+00	907.00
IUUC-Bra-017522	Brassica rapa	46.29	0.00e+00	892.00
IUUC-Cel-018260	Caenorhabditis elegans	48.99	0.00e+00	948.00
IUUC-Cja-019152	Callithrix jacchus	87.24	0.00e+00	1923.00
IUUC-Cfa-020622	Canis familiaris	85.26	0.00e+00	1853.00
IUUC-Cpo-022526	Cavia porcellus	87.24	0.00e+00	1901.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	44.94	0.00e+00	844.00
IUUC-Csa-023780	Chlorocebus sabaeus	87.62	0.00e+00	1931.00
IUUC-Cin-025790	Ciona intestinalis	63.18	0.00e+00	1363.00
IUUC-Csv-026084	Ciona savignyi	60.72	0.00e+00	1344.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	53.92	0.00e+00	1095.00
IUUC-Cne-026960	Cryptococcus neoformans	55.75	0.00e+00	1117.00
IUUC-Cme-027290	Cyanidioschyzon merolae	44.48	0.00e+00	826.00
IUUC-Dre-028149	Danio rerio	78.47	0.00e+00	1701.00
IUUC-Dno-028884	Dasypus novemcinctus	87.43	0.00e+00	1932.00
IUUC-Dor-030229	Dipodomys ordii	82.80	0.00e+00	1815.00
IUUC-Dse-031524	Dothistroma septosporum	51.44	0.00e+00	1048.00
IUUC-Dme-032045	Drosophila melanogaster	60.04	0.00e+00	1271.00
IUUC-Ete-032544	Echinops telfairi	75.81	0.00e+00	800.00
IUUC-Eca-033330	Equus caballus	87.81	0.00e+00	1941.00
IUUC-Fca-036255	Felis catus	87.81	0.00e+00	1925.00
IUUC-Fal-037445	Ficedula albicollis	49.79	0.00e+00	878.00
IUUC-Fox-038007	Fusarium oxysporum	54.02	5.00e-166	577.00
IUUC-Fso-038339	Fusarium solani	53.56	0.00e+00	1045.00
IUUC-Gmo-039338	Gadus morhua	74.47	0.00e+00	1593.00
IUUC-Ggr-039823	Gaeumannomyces graminis	53.85	0.00e+00	1105.00
IUUC-Gga-040365	Gallus gallus	47.95	0.00e+00	801.00
IUUC-Gac-041773	Gasterosteus aculeatus	74.95	0.00e+00	1592.00
IUUC-Gma-043165	Glycine max	44.70	0.00e+00	905.00
IUUC-Ggo-045336	Gorilla gorilla	88.00	0.00e+00	1913.00
IUUC-Hsa-045982	Homo sapiens	87.71	0.00e+00	1907.00
IUUC-Hvu-047418	Hordeum vulgare	46.15	0.00e+00	878.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	87.81	0.00e+00	1933.00
IUUC-Kpa-049112	Komagataella pastoris	50.83	0.00e+00	1001.00
IUUC-Lch-050371	Latimeria chalumnae	79.32	0.00e+00	1761.00
IUUC-Lpe-051299	Leersia perrieri	44.33	0.00e+00	892.00
IUUC-Loc-052936	Lepisosteus oculatus	79.89	0.00e+00	1740.00
IUUC-Lma-053315	Leptosphaeria maculans	52.38	0.00e+00	1079.00
IUUC-Laf-053948	Loxodonta africana	85.07	0.00e+00	1874.00
IUUC-Mcc-055843	Macaca mulatta	87.52	0.00e+00	1932.00
IUUC-Meu-056258	Macropus eugenii	93.01	0.00e+00	2026.00
IUUC-Mor-057269	Magnaporthe oryzae	53.22	0.00e+00	1078.00
IUUC-Mpo-057435	Magnaporthe poae	53.52	0.00e+00	1066.00
IUUC-Mtr-058572	Medicago truncatula	45.63	0.00e+00	877.00
IUUC-Mla-059176	Melampsora laricipopulina	55.18	0.00e+00	1083.00
IUUC-Mvi-060437	Microbotryum violaceum	54.17	0.00e+00	1063.00
IUUC-Mmr-061405	Microcebus murinus	85.07	0.00e+00	1863.00
IUUC-Mdo-062032	Monodelphis domestica	91.10	0.00e+00	1995.00
IUUC-Mmu-063280	Mus musculus	86.20	0.00e+00	1885.00
IUUC-Mac-065505	Musa acuminata	45.44	0.00e+00	887.00
IUUC-Mpu-066409	Mustela putorius furo	87.24	0.00e+00	1930.00
IUUC-Mlu-067217	Myotis lucifugus	86.48	0.00e+00	1904.00
IUUC-Nfi-068407	Neosartorya fischeri	53.86	0.00e+00	1054.00
IUUC-Ncr-068698	Neurospora crassa	53.89	0.00e+00	1089.00
IUUC-Nle-070072	Nomascus leucogenys	82.95	0.00e+00	1789.00
IUUC-Ont-071671	Oreochromis niloticus	77.15	0.00e+00	1665.00
IUUC-Ocu-074544	Oryctolagus cuniculus	87.43	0.00e+00	1934.00
IUUC-Oba-075120	Oryza barthii	46.19	0.00e+00	881.00
IUUC-Obr-076557	Oryza brachyantha	46.47	0.00e+00	873.00
IUUC-Ogl-077887	Oryza glaberrima	46.19	0.00e+00	884.00
IUUC-Ogu-078305	Oryza glumaepatula	44.36	0.00e+00	884.00
IUUC-Oin-080154	Oryza indica	44.42	0.00e+00	885.00
IUUC-Olo-081089	Oryza longistaminata	44.42	0.00e+00	885.00
IUUC-Ome-081942	Oryza meridionalis	46.19	0.00e+00	880.00
IUUC-Oni-082365	Oryza nivara	46.09	0.00e+00	883.00
IUUC-Opu-083977	Oryza punctata	46.37	0.00e+00	884.00
IUUC-Oru-084469	Oryza rufipogon	44.42	0.00e+00	886.00
IUUC-Osa-085949	Oryza sativa	46.29	0.00e+00	891.00
IUUC-Ola-087002	Oryzias latipes	76.29	0.00e+00	1648.00
IUUC-Olu-087687	Ostreococcus lucimarinus	45.04	0.00e+00	820.00
IUUC-Oga-088594	Otolemur garnettii	86.87	0.00e+00	1887.00
IUUC-Oar-090068	Ovis aries	87.54	0.00e+00	1932.00
IUUC-Pan-092114	Papio anubis	87.62	0.00e+00	1934.00
IUUC-Pma-094214	Petromyzon marinus	58.29	4.00e-53	200.00
IUUC-Pno-095154	Phaeosphaeria nodorum	52.28	0.00e+00	1077.00
IUUC-Ppa-095416	Physcomitrella patens	45.67	0.00e+00	894.00
IUUC-Pfo-097184	Poecilia formosa	76.00	0.00e+00	1643.00
IUUC-Pab-097861	Pongo abelii	87.71	0.00e+00	1898.00
IUUC-Pop-098934	Populus trichocarpa	44.91	0.00e+00	915.00
IUUC-Pca-100347	Procavia capensis	83.30	0.00e+00	1519.00
IUUC-Ppe-102012	Prunus persica	44.54	0.00e+00	898.00
IUUC-Pva-102584	Pteropus vampyrus	87.71	0.00e+00	1951.00
IUUC-Pgr-103336	Puccinia graminis	54.41	0.00e+00	1060.00
IUUC-Ptt-103939	Puccinia triticina	54.31	0.00e+00	1058.00
IUUC-Pte-104200	Pyrenophora teres	52.19	0.00e+00	1080.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	51.20	0.00e+00	1070.00
IUUC-Rno-105462	Rattus norvegicus	86.86	0.00e+00	1886.00
IUUC-Sce-106245	Saccharomyces cerevisiae	51.57	0.00e+00	1065.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	53.43	0.00e+00	1105.00
IUUC-Spo-108034	Schizosaccharomyces pombe	52.91	0.00e+00	1068.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	54.39	0.00e+00	1047.00
IUUC-Smo-109211	Selaginella moellendorffii	45.44	0.00e+00	881.00
IUUC-Sit-110281	Setaria italica	45.54	0.00e+00	905.00
IUUC-Sly-110914	Solanum lycopersicum	44.52	0.00e+00	899.00
IUUC-Stu-112109	Solanum tuberosum	44.33	0.00e+00	905.00
IUUC-Sar-113737	Sorex araneus	86.39	0.00e+00	1902.00
IUUC-Sbi-114089	Sorghum bicolor	45.39	0.00e+00	901.00
IUUC-Sre-115148	Sporisorium reilianum	54.35	0.00e+00	1078.00
IUUC-Ssc-115777	Sus scrofa	87.63	0.00e+00	1933.00
IUUC-Tru-118742	Takifugu rubripes	77.25	0.00e+00	1618.00
IUUC-Tni-120401	Tetraodon nigroviridis	77.15	0.00e+00	1612.00
IUUC-Tca-121672	Theobroma cacao	44.57	0.00e+00	903.00
IUUC-Tre-122009	Trichoderma reesei	52.94	0.00e+00	1036.00
IUUC-Tvi-122259	Trichoderma virens	53.53	0.00e+00	1026.00
IUUC-Tae-125113	Triticum aestivum	46.67	0.00e+00	858.00
IUUC-Tur-126189	Triticum urartu	46.42	0.00e+00	853.00
IUUC-Tme-127055	Tuber melanosporum	52.01	0.00e+00	991.00
IUUC-Tbe-127487	Tupaia belangeri	85.07	0.00e+00	941.00
IUUC-Ttr-128331	Tursiops truncatus	87.24	0.00e+00	1914.00
IUUC-Uma-129387	Ustilago maydis	54.22	0.00e+00	1077.00
IUUC-Vda-129977	Verticillium dahliae	53.94	0.00e+00	1013.00
IUUC-Vvi-130857	Vitis vinifera	45.35	0.00e+00	903.00
IUUC-Xtr-132026	Xenopus tropicalis	63.55	0.00e+00	1276.00
IUUC-Xma-133805	Xiphophorus maculatus	75.72	0.00e+00	1622.00
IUUC-Yli-134547	Yarrowia lipolytica	53.45	0.00e+00	1088.00
IUUC-Zma-135052	Zea mays	45.18	0.00e+00	902.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence