iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062787

Ensembl Protein ID

ENSMODP00000000506.1

UniProt Accession

F6VAK8; F6VAK8_MONDO

Protein Name

O-phosphoseryl-tRNA(Sec) selenium transferase; Selenocysteine synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep-tRNA:Sec-tRNA synthase

Gene Name

SEPSECS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000423.3	ENSMODT00000000520.2	ENSMODP00000000506.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/BCR/BTB_Other	25.23	5.30e-02	33.90	IUUC-Spo-108232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Functional Description
(View)

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.

Protein Sequence
(Fasta)

MNCENFAAGE RLVTPAYVRQ GCEARRSHEH LIRLLLEKGK CPEDGWDEST IELFLHELAI 60
MDSNNFLGNC GVGEREGRVA SGLVARRHYR FIHGIGRSGD IAAVQPKAAG SSLLNKIANL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCACTGTT CCTATTGTTC CTGGTAGTCT TCACGCATGC TCCTCCCTAG TCTCATTGGT 60
TGGCTAGGCG GAAGAGTGGG AGGGGGAAAG CTGCGCAGTC GCGCACGCGT AAATGTACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0648--Protein biosynthesis
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0711--Selenium
KW-0808--Transferase
KW-0820--tRNA-binding

Interpro

IPR015424--PyrdxlP-dep_Trfase
IPR015421--PyrdxlP-dep_Trfase_major_sub1
IPR019872--Sec-tRNA_Se_transferase
IPR008829--SepSecS/SepCysS

Pfam

PF05889--SepSecS

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0016785--F:transferase activity, transferring selenium-containing groups
GO:0000049--F:tRNA binding
GO:0001514--P:selenocysteine incorporation
GO:0097056--P:selenocysteinyl-tRNA(Sec) biosynthetic process

KEGG

mdo:100011061

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Pma-094691	Petromyzon marinus	36.96	1.10e+00	27.70

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence